Abstract:
PURPOSE:To evaluate choroidal thickness, macular thickness, and peripapillary retinal nerve fiber layer (RNFL) thickness in amblyopic eyes compared to fellow and normal control eyes using high-definition spectral-domain optical coherence tomography (SD-OCT). METHODS:Fifty-four without any systemic problem and ocular disease participated in this prospective study. Inclusion criteria included individuals older than 18 years with anisometropic amblyopia. Choroidal thickness, central macular thickness (CMT), and RNFL thickness were measured by using enhanced depth imaging SD-OCT. The choroidal thickness was measured at the fovea and at 500 µm intervals from the foveal center in both temporal and nasal directions. Axial length measurements of the cases were also recorded. RESULTS:Mean peripapillary RNFL thickness of the amblyopic, fellow, and control eyes was 107.5 ± 15.5 µm, 109.3 ± 12.7 µm, and 108.8 ± 8.6 µm, respectively (p = 0.343). The average CMT was 231.7 ± 14.7 µm in amblyopic eyes, 232.5 ± 15.7 μm in fellow eyes, and 230.8 ± 14.8 µm in control eyes (p = 0.599). Mean subfoveal choroidal thickness was significantly greater in the amblyopic eyes than in the fellow and control eyes (396.3 ± 104.3 µm, 361.0 ± 103.9 µm, 390.6 ± 91.7 µm). Mean axial measurement in amblyopic eyes was 22.7 ± 1.3 mm (20.5-26.1), in fellow eyes 23.1 ± 0.9 mm (20.9-25.0), and in control eyes 23.3 ± 0.9 mm. CONCLUSIONS:In adults with anisometropic amblyopia, subfoveal, temporal, and nasal choroidal thickness of amblyopic eyes are significantly thicker than in fellow eyes. However, no significant differences in peripapillary RNFL thickness or CMT were found between amblyopic and fellow or control eyes.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Kantarci FA,Tatar MG,Uslu H,Colak HN,Yildirim A,Goker H,Gurler Bdoi
10.5301/ejo.5000594subject
Has Abstractpub_date
2015-09-01 00:00:00pages
437-42issue
5eissn
1120-6721issn
1724-6016pii
829AB44B-0AE5-4102-B671-68CE8A582EBCjournal_volume
25pub_type
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