Lacrimal function and ocular complications in patients treated with systemic isotretinoin.

Abstract:

PURPOSE:To evaluate the effect on lacrimal function and ocular complications in patients with severe acne vulgaris during systemic treatment with 13-cis-retinoic acid (isotretinoin). METHODS:Forty patients with acne vulgaris were treated with systemic isotretinoin at dosages of 0.5-1 mg/kg per day for two months. Full ophthalmologic examination, Schirmer I test, fluorescein break-up (BUT) and microbiological investigations of the conjunctival flora were done before, during the second month and at least one month after the end of the treatment. RESULTS:The average Schirmer values before and after the treatment were 21.6 mm/5 minutes (SD +/- 7.01) and 18.48 mm/5 minutes (SD +/- 7.87) respectively. After the treatment BUT was less than 10 seconds in 50% of the patients and 55% had blepharitis. Subjective symptoms like dryness, itching and contact lens intolerance occurred in 42.5% and colonization of the conjunctiva by Staphylococcus aureus increased significantly during treatment (p= 0.031). All abnormal findings disappeared one month after the cessation of treatment. DISCUSSION:Isotretinoin causes signs and symptoms of dry eye, probably by reducing meibomian gland function, but ocular complications are generally not serious when low doses are used for a limited time, and are reversible after discontinuation.

journal_name

Eur J Ophthalmol

authors

Bozkurt B,Irkeç MT,Atakan N,Orhan M,Geyik PO

subject

Has Abstract

pub_date

2002-05-01 00:00:00

pages

173-6

issue

3

eissn

1120-6721

issn

1724-6016

journal_volume

12

pub_type

杂志文章
  • Information used to decide on retreatment of exudative age-related macular degeneration with 
anti-VEGF in clinical practice.

    abstract::Purpose. To record the information used in order to make a retreatment decision in patients with exudative age-related macular degeneration (AMD) and to assess if an optical coherence tomography (OCT)-only follow-up clinic would suffice.
Methods. Two hundred patients under treatment with intravitreal anti-vascular end...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000190

    authors: Manousaridis K,Manjunath V,Talks J

    更新日期:2012-08-06 00:00:00

  • Late endoscopic evaluation of the ostium size after external dacryocystorhinostomy.

    abstract:OBJECTIVE:To evaluate the effect of chronicity on the size of the ostium after external dacryocystorhinostomy (DCR) with intubation. METHODS:Design: A retrospective chart review of patients who underwent external DCR with intubation over 10 years from January 2003 at a tertiary hospital. All patients were recruited an...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120976044

    authors: Al Huthail RR,Al-Faky YH

    更新日期:2020-11-24 00:00:00

  • Hyperthyroidism and severity of orbital disease do not change the central corneal thickness in Graves'' ophthalmopathy.

    abstract:PURPOSE:To investigate whether the central corneal thickness (CCT) shows alterations in Graves disease and Graves ophthalmopathy (GO) cases according to the disease severity and hormonal status of the patients. METHODS:A total of 150 patients (62 male, 88 female) with Graves disease and 32 control subjects (11 male, 2...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/EJO.2008.399

    authors: Unal M,Onol M,Konuk O,Aktas Z,Aksoy S

    更新日期:2008-01-01 00:00:00

  • Burn during a routine pterygium excision operation.

    abstract:PURPOSE:To report a patient who sustained a spark fire burn during a routine pterygium operation. METHODS:A 40-year-old woman was referred for pterygium excision in her left eye. During the operation a low temperature cautery caused a spark fire that resulted in left eye corneal burn, upper and lower eyelid burns, and...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210801800425

    authors: Naftali M,Jabaly-Habib H,Mukari A

    更新日期:2008-07-01 00:00:00

  • Retained lens fragments: nucleus fragments are associated with worse prognosis than cortex or epinucleus fragments.

    abstract:PURPOSE:To identify factors that determined the outcome of eyes that underwent pars plana vitrectomy for retained lens fragments after phacoemulsification. METHODS:A retrospective review of the records of 63 eyes that underwent vitrectomy for retained lens fragments after phacoemulsification. Fragments were defined as...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/EJO.2011.6483

    authors: Moisseiev E,Kinori M,Glovinsky Y,Loewenstein A,Moisseiev J,Barak A

    更新日期:2011-11-01 00:00:00

  • Divergent strabismus fixus--a case report.

    abstract::Strabismus fixus is a rare condition and usually is of convergent type in which one or both eyes are anchored in a position of extreme adduction. Convergent type strabismus fixus is considered to be a congenital disorder and a part of congenital extraocular muscle fibrosis syndrome. Villasecca and Martinez described a...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210301300214

    authors: Sharma TK,Grewal JS,MacDonald M

    更新日期:2003-03-01 00:00:00

  • Efficacy and side effects of latanoprost monotherapy compared to adding dorzolamide to timolol in patients with glaucoma and ocular hypertension - A three-month randomised study.

    abstract:PURPOSE:To compare the efficacy and safety of latanoprost monotherapy or dorzolamide and timolol in glaucoma patients inadequately controlled on adrenergic beta-receptor antagonist therapy. METHODS:A total of 164 patients with primary open-angle glaucoma, capsular glaucoma or ocular hypertension were included in a thr...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/EJO.2008.5687

    authors: Garcia Sanchez J,The Spanish Latanoprost Study Group A

    更新日期:2000-07-01 00:00:00

  • Luxated intraocular lens fixation using anterior chamber slipknot of the haptic to the sclera: a simple procedure to fixate intraocular lens to the sclera.

    abstract:PURPOSE:To describe a technique for suturing a luxated intraocular lens (IOL) in the vitreous cavity directly to the ciliary sulcus using intraocular slipknot without IOL extraction. DESIGN:Noncomparative interventional case series. MATERIALS AND METHODS:A three-port vitrectomy was performed in all cases. According t...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210301300604

    authors: Micelli Ferrari T,Cardascia N,Furino C,Recchimurzo N,Boscia F,Sborgia L

    更新日期:2003-07-01 00:00:00

  • Effect of intraocular pressure lowering on the capillary density of optic nerve head and retinal nerve fiber layer in patients with glaucoma.

    abstract:PURPOSE:To evaluate the effect of IOP lowering on the capillary density of optic nerve head and retinal nerve fiber layer in patients with primary open angle glaucoma. METHODS:Twenty eyes of 14 glaucomatous patients and 15 eyes of nine normal patients were enrolled. The most appropriate hypotonic treatment was applied...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120967233

    authors: de Paula A,Perdicchi A,Di Tizio F,Fragiotta S,Scuderi G

    更新日期:2020-10-29 00:00:00

  • Dacryo-fornix-rhinostomy with two flaps.

    abstract::The two most frequent sites of obstruction of the lacrimal pathways are under the lacrimal sac, in the ductus lacrimonasalis, and over the lacrimal sac, in the canaliculi. The obstruction of the first type already has a satisfactory solution with the different forms of dacryo-cysto-rhinostomies. Obstruction of the sec...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Murube del Castillo J,Martinez Baradas A,Hernandez King J,Cruz Vilella ME,Bahamon Caycedo M

    更新日期:1992-04-01 00:00:00

  • Studying the role of 10-2 visual field test in different stages of glaucoma.

    abstract:OBJECTIVE:To assess the role of 10-2 visual field (VF) test in different stages of glaucoma. METHODS:In our prospective comparative study, 24-2 and 10-2 VF tests were done for 115 eyes with different stages of glaucomatous damage or glaucoma suspects. Optical coherence tomography (OCT) was performed in 79 eyes. We com...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672119836904

    authors: Tomairek RH,Aboud SA,Hassan M,Mohamed AH

    更新日期:2020-07-01 00:00:00

  • Deep sclerectomy in primary open-angle glaucoma and exfoliative glaucoma.

    abstract:PURPOSE:To study the effect of deep sclerectomy (DS) in primary open-angle glaucoma (POAG) and exfoliative glaucoma (EXG). METHODS:We retrospectively analyzed the intraocular pressure (IOP)-lowering effect of DS in 235 consecutive eyes. Eyes were divided into 2 groups according to glaucoma subtype: POAG (127 eyes) and...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000762

    authors: Suominen SM,Harju MP,Vesti ET

    更新日期:2016-11-04 00:00:00

  • Visual phenotype of multiple sclerosis in the Afro-Caribbean population and the influence of migration to metropolitan France.

    abstract:PURPOSE:To describe the visual phenotype of multiple sclerosis (MS) in the Afro-Caribbean population living in Martinique (French West Indies) and to specify the influence of the migration to metropolitan France on ocular impairment. DESIGN:Prospective consecutive observational case series. METHODS:A complete ophthal...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210501500313

    authors: Merle H,Smadja D,Merle S,Olindo S,Signate A,Donnio A,Richer R,Bonnan M,Cabre P

    更新日期:2005-05-01 00:00:00

  • Long-term (>8 years) evaluation of progression in patients with low-pressure glaucoma.

    abstract:PURPOSE:To describe the long-term clinical course of patients with low-pressure glaucoma (LPG) and to assess the risk factors for disease progression. METHODS:The Wills Eye Glaucoma Research Center retrospectively reviewed the charts of LPG patients with documented follow-up of >8 years between 2000 and 2013. Medical ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000624

    authors: Erdem E,Williams A,Kuchar SD,Waisbourd M,Spaeth GL

    更新日期:2015-11-01 00:00:00

  • Comparison of performance between two microcatheter systems in ab externo canaloplasty: A retrospective comparison study.

    abstract:PURPOSE:To compare the performance of two different microcatheter systems, iTrack™ 250A and Glaucolight, in ab externo canaloplasty in three major categories: intraocular pressure reduction, drug therapy reintroduction, and evaluation of viscodilation over distension of the inner wall of Schlemm's canal. METHODS:A tot...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672119833547

    authors: Vastardis I,Kontopoulou K,Fili S,Gatzioufas Z,Kohlhaas M

    更新日期:2020-05-01 00:00:00

  • SD-OCT stages of progression of type 2 macular telangiectasia in a patient followed for 3 years.

    abstract:PURPOSE:To describe the natural course of type 2 idiopathic macular telangiectasia (MT) using spectral-domain optical coherence tomography (SD-OCT). METHODS:Analysis of the different stages of progression of type 2 MT during a period of 3 years using multimodal imaging, including SD-OCT correlated with angiographic an...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000363

    authors: Coscas G,Coscas F,Zucchiatti I,Bandello F,Soubrane G,SouÏed E

    更新日期:2013-11-01 00:00:00

  • Late postoperative capsular block syndrome: a case series studied before and after Nd:YAG laser posterior capsulotomy.

    abstract:PURPOSE:To evaluate the clinical characteristics of the unusual late postoperative capsular block syndrome (CBS) and the effect of Nd:YAG laser posterior capsulotomy on visual acuity and refractive error as well as its possible complications. METHODS:In this retrospective cohort study, 12 eyes of 11 patients with late...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000507

    authors: Huerva V,Sánchez MC,Ascaso FJ,Soldevila J

    更新日期:2015-01-01 00:00:00

  • Diagnostic capability of optic nerve head rim width and retinal nerve fiber thickness in open-angle glaucoma.

    abstract:PURPOSE:This study was performed to test the diagnostic capability of the minimum rim width compared to peripapillary retinal nerve fiber layer thickness in patients with glaucoma. METHODS:A case control, observer masked study, was conducted. Minimum rim width and retinal nerve fiber layer thickness were assessed usin...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672117750057

    authors: Di Staso S,Agnifili L,Di Staso F,Climastone H,Ciancaglini M,Scuderi GL

    更新日期:2018-07-01 00:00:00

  • Ocular complications of Garcinia cambogia extract diet pills: Case report.

    abstract:BACKGROUND:Garcinia cambogia contains hydroxycitric acid. Hydroxycitric acid is a potent competitive inhibitor of adenosine triphosphate citrate lyase which is a key enzyme in the synthesis of fatty acids. Hydroxycitric acid also regulates the level of serotonin. In these regards, hydroxycitric acid has been reported t...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672119872364

    authors: Cho HK,Han YS,Park JM

    更新日期:2020-11-01 00:00:00

  • Multiorganism, drug-resistant keratitis treated by corneal crosslinking.

    abstract:PURPOSE:To describe a case of multiorganism, drug-resistant keratitis that responded well to corneal crosslinking (CXL) treatment. METHODS:A 52-year-old man presented to our institute with a 2-month ocular history of infectious keratitis in his right eye, on topical antibacterial, antifungal, and antiprotozoan treatme...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000755

    authors: Kymionis GD,Kouroupaki AI,Liakopoulos DA,Arandjelovic IR,Tsoulnaras KI

    更新日期:2016-07-01 00:00:00

  • Sympathetic ophthalmia associated with ocular and cerebral vasculitis: an angiographic and radiologic study.

    abstract:PURPOSE:To describe a case of sympathetic ophthalmia (SO) associated with ocular and cerebral vasculitis. METHODS:The authors report a 38-year-old woman who presented with bilateral uveitis 7 years after a penetrating trauma to the right eye. Ocular examination included fundus fluorescein and indocyanine green angiogr...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210301300614

    authors: Kadayifçilar S,Irkeç M,Eldem B

    更新日期:2003-07-01 00:00:00

  • Sulcus implantation of a single-piece foldable acrylic intraocular lens after posterior capsular rupture in cataract surgery.

    abstract:PURPOSE:To evaluate the safety of a foldable acrylic single-piece intraocular lens (IOL) in cases of complicated cataract surgery and sulcus implantation. The setting was University and private anterior segment surgery practices. METHODS:In this observational case series study, 13 eyes of 13 patients were included aft...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000160

    authors: Renieri G,Herzog D,Niemann S,Becker M,Kurz S,Thieme H

    更新日期:2012-11-01 00:00:00

  • Ocular and orbital complications following the treatment of retinoblastoma.

    abstract:PURPOSE:To investigate the ocular and orbital complications observed in children treated for retinoblastoma. SUBJECTS AND METHODS:We retrospectively studied 73 children (39 boys, 34 girls) suffering from retinoblastoma. Thirty-six had bilateral tumor and 37 unilateral disease for a total of 109 eyes affected. The foll...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Anteby I,Ramu N,Gradstein L,Miskin H,Pe'er J,Benezra D

    更新日期:1998-04-01 00:00:00

  • Unusual presentation of giant cell angiofibroma of the eyelids.

    abstract:PURPOSE:To describe a case of bilateral eyelid-confined giant cell angiofibroma (GCAF) in a patient with a slowly progressive bilateral eyelid swelling. METHODS:A 40-year-old man with a 5-year history of slowly progressive bilateral eyelid swelling, severe functional impairment, and bilateral cosmetic deformity was st...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067211002000608

    authors: Surace D,Blandamura S,Bernardini FP,Galan A,Lo Giudice G

    更新日期:2010-11-01 00:00:00

  • Bilateral complete avulsion of ocular globes in a Le Fort III maxillofacial fracture: a case report and review of the literature.

    abstract:PURPOSE:The purpose of this paper is to demonstrate a case of bilateral complete avulsion of the globes following maxillofacial trauma. METHODS:A 23-year-old man with bilateral complete globe avulsion following a maxillofacial trauma. Both globes were luxated out of the orbit and suspended on the skin of the upper lid...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210501500119

    authors: Unal S,Argin A,Arslan E,Demirkan F,Aksoy A

    更新日期:2005-01-01 00:00:00

  • Conjunctival scrapings and impression cytology in chronic conjunctivitis. Correlation with microbiology.

    abstract::To assess the utility of exfoliative cytology in the diagnosis of chronic conjunctivitis, we compared its findings with microbiological examination and established the correlation between cytology and microbiology in 32 patients with conjunctivitis lasting four weeks or more, with a nonspecific clinical picture. The m...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Cvenkel B,Globocnik M

    更新日期:1997-01-01 00:00:00

  • Regression patterns of choroidal melanoma: After palladium-103 (103Pd) plaque brachytherapy.

    abstract:PURPOSE::To describe the patterns of regression of choroidal melanoma after treatment with plaque brachytherapy. METHODS::Retrospective interventional case series including 170 consecutive patients treated with 103Pd eye plaque radiation for choroidal melanoma. Outcome measures were changes in tumor thickness, surface...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672118776146

    authors: Maheshwari A,Finger PT

    更新日期:2018-11-01 00:00:00

  • Should we worry about the eyes of celiac patients?

    abstract:PURPOSE:In this article, we evaluate subfoveal choroidal thickness in celiac patients with respect to adherence to the gluten-free diet and nonadherence to the gluten-free diet, comparing with age and sex matched healthy controls using spectral-domain optical coherence tomography. MATERIALS AND METHODS:A case-control ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672119850071

    authors: Doğan G,Şen S,Çavdar E,Mayalı H,Cengiz Özyurt B,Kurt E,Kasırga E

    更新日期:2020-09-01 00:00:00

  • Morbidity of malignant tumours with ocular location in the Bulgarian district of Plovdiv.

    abstract:PURPOSE:To study the actual and standardized morbidity of malignant tumours with ocular location (per 100,000 inhabitants) over a period of ten years. METHODS:Retrospective evaluation of the registers of the Plovdiv District Oncology Centre and the Department of Ophthalmology in the Medical University. It includes 698...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Atanassova-Chilova BK

    更新日期:1996-04-01 00:00:00

  • Escherichia coli endophthalmitis after trans-scleral resection of uveal melanoma.

    abstract:PURPOSE:To report a case of Escherichia coli endophthalmitis after trans-scleral resection of an uveal melanoma. METHODS:A large ciliary body melanoma was treated by trans-scleral resection and full-thickness sclerectomy because of epibulbar tumor extrusion, followed by adjuvant ruthenium plaque therapy. RESULTS:Two ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210201200517

    authors: Balestrazzi A,Blasi MA,Primitivo S,Balestrazzi E

    更新日期:2002-09-01 00:00:00