Abstract：
PURPOSE:Retinopathy is the major cause of ocular morbidity in patients with diabetes mellitus. Chronic hyperglycemia spares no organ and can affect the morphology and function of the various corneal layers, compromising its transparency. This study was conducted to associate the status of corneal endothelium to diabetes mellitus (DM) and identify risk factors of compromised corneal endothelium. METHODS:A total of 220 eyes of randomly selected patients (110 diabetic and 110 nondiabetic) were subjected to detailed slitlamp and fundus evaluation. Corneal endothelial status was evaluated using the Nidek Confoscan 2. Cell density, percentage polymegathism, and pleomorphism were calculated. The findings in diabetic patients were compared to those without disease. The outcome was correlated to diabetic retinopathy (DR). The effects of hypertension, hyperlipidemia, age, gender, type, duration, glycemic control, and grades of DR was also considered. RESULTS:The mean corneal endothelial cell density was -175 cells/mm2 (95% CI -317 to -33 cells/mm2) less in eyes of diabetic patients. The number of endothelial cells with polymegathism was significantly greater among eyes of diabetic patients. There were less corneal endothelial cells with pleomorphism in nondiabetic patients. Polymegathism and pleomorphism of corneal endothelial cells seems to be positively associated with DM type II. Cell density was significantly lower in eyes with DR than those without DR. CONCLUSIONS:Corneal endothelium in diabetic patients seems to be compromised. Evaluation of corneal endothelium should be part of protocol for eye care of diabetic patients.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Shenoy R,Khandekar R,Bialasiewicz A,Al Muniri Adoi
10.1177/112067210901900307subject
Has Abstractpub_date
2009-05-01 00:00:00pages
369-75issue
3eissn
1120-6721issn
1724-6016journal_volume
19pub_type
杂志文章abstract：PURPOSE:To report a case of recurrent cytomegalovirus (CMV) corneal endotheliitis after penetrating keratoplasty. METHODS:Penetrating keratoplasty (PK) was performed in a 49-year-old man with bullous keratopathy. Pigmented keratic precipitates (KPs) were found in the corneal endothelium of the graft 13 days after surg...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067211002000231
更新日期：2010-03-01 00:00:00
abstract：PURPOSE:The aim of this study was to report the 12-year longitudinal trends in indication and corneal transplantation techniques in France from 2004 to 2015. RESULTS:The records of all corneal transplantations performed from 2004 to 2015 in France were retrospectively reviewed. The patient indications and types of tra...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672118762224
更新日期：2018-09-01 00:00:00
abstract：INTRODUCTION::The purpose of the study was to estimate the number of people with diabetes mellitus, the prevalence of diabetes mellitus and the prevalence of blindness and severe visual impairment among people with diabetes mellitus in Hungary based on our recent national representative survey. METHODS::Altogether 105...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1177/1120672118811738
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:Two cases with optic disc pit associated maculopathy, treated with vitrectomy surgery with internal limiting membrane peeling (ILM) and gas tamponade, are presented. METHODS:Interventional case reports. RESULTS:Two patients with serous macular detachment associated with a congenital optic pit underwent vitrec...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210901900230
更新日期：2009-03-01 00:00:00
abstract：PURPOSE:To review the current practice of retreatment with Ozurdex injections in patients with macular edema (ME) secondary to retinal vein occlusion (RVO), and to recommend simple guidelines for Ozurdex reinjection in management of RVO. METHODS:This was a multicenter retrospective study of patients who received more ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.5301/ejo.5000376
更新日期：2014-01-01 00:00:00
abstract：SIGNIFICANCE:Susac's syndrome is a rare retinocochleocerebral immune-mediated endotheliopathy and clinically manifests as a pathognomonic triad of encephalopathy, hearing loss, and branch retinal artery occlusion. This triad is rarely present at symptom onset, thus, it is often initially misdiagnosed. To date, Susac's ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120924545
更新日期：2020-05-07 00:00:00
abstract：PURPOSE:Intravitreal implantation of dexamethasone implant (Ozurdex®) is being widely used for the treatment of macular edema (ME) after branch or central retinal vein occlusion, diabetic ME, and persistent ME associated with uveitis or Irvine-Gass syndrome. We describe a complication: migration of the dexamethasone im...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000715
更新日期：2016-04-12 00:00:00
abstract：PURPOSE:To report the laboratory findings, management strategies, and visual outcomes of culture-proven exogenous fungal endophthalmitis in North China. METHODS:The microbiological and treatment records of patients with culture-positive exogenous fungal endophthalmitis who visited the Affiliated Hospital of Qingdao Un...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672119833896
更新日期：2020-05-01 00:00:00
abstract：:We present an unusual case of Sturge-Weber syndrome whose main clinical manifestations were nevus flammeus, seizures, glaucoma, and acoria. To our knowledge, the combination of Sturge-Weber syndrome and acoria has not been previously reported. ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672118804795
更新日期：2020-01-01 00:00:00
abstract：PURPOSE:Several types of inborn errors of the O-glycan biosynthesis are known, leading to clinically very distinct phenotypes. Children with O-mannosyl glycan biosynthesis defects commonly present as a severe form of congenital muscular dystrophy with decreased alpha-dystroglycan staining, congenital eye anomalies, and...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210601600134
更新日期：2006-01-01 00:00:00
abstract：PURPOSE:The aim of this study is to assess the agreement between manual and automated gonioscopy for iridocorneal angle opening. METHODS:The research is a cross-sectional observational study. Manual and automated gonioscopy were performed to consecutive patients in a glaucoma clinic. Iridocorneal angle opening grading...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672118806436
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:The aim of this article was to study the lower punctum parameters in patients with acquired punctal stenosis using spectral-domain anterior segment optical coherence tomography. SUBJECTS/METHODS:This was a prospective nonrandomized study that included two groups. Group 1 was composed of 32 puncta...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672119871396
更新日期：2019-09-06 00:00:00
abstract：PURPOSE:To study the correlation between final visual acuity after successful anatomic macular hole repair and features on spectral domain optical coherence tomography (SD-OCT). METHODS:Retrospective review of charts of patients who underwent macular hole surgery. Data collection included pre- and postoperative best-c...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067211002000306
更新日期：2010-05-01 00:00:00
abstract：PURPOSE:To determine the long-term visual outcomes and risk factors for visual loss in children with primary congenital glaucoma (PCG) who underwent angle surgery over a 21-year period. METHODS:This was a retrospective study of patients who underwent trabeculotomy, trabeculectomy, or combined trabeculotomy-trabeculect...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000976
更新日期：2017-11-08 00:00:00
abstract：PURPOSE:To assess whether a screening method based on transcranial Doppler (TCD) examination could detect signs of brain hemodynamic impairment in non-insulin-dependent diabetic patients with retinal microangiopathy of varying severity, asymptomatic for cerebrovascular diseases. METHODS:We studied 86 patients stratifi...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1997-04-01 00:00:00
abstract：PURPOSE::To evaluate the predictive value of magnetic resonance imaging in retinoblastoma for the likelihood of high-risk pathologic features. METHODS::A retrospective study of 64 eyes enucleated from 60 retinoblastoma patients. Contrast-enhanced magnetic resonance imaging was performed before enucleation. Main outcom...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672118781200
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:To study the actual and standardized morbidity of malignant tumours with ocular location (per 100,000 inhabitants) over a period of ten years. METHODS:Retrospective evaluation of the registers of the Plovdiv District Oncology Centre and the Department of Ophthalmology in the Medical University. It includes 698...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：PURPOSE:To report a corneal transplant complication associated with intracameral recombinant tissue plasminogen activator (rTPA) treatment of postoperative fibrin reaction. METHODS:In a 71-year-old patient, a triple procedure was performed for perforated rheumatic ulcer and secondary cataract. RESULTS:A dense band ke...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210701700328
更新日期：2007-05-01 00:00:00
abstract：PURPOSE:The purpose of this paper is to demonstrate a case of bilateral complete avulsion of the globes following maxillofacial trauma. METHODS:A 23-year-old man with bilateral complete globe avulsion following a maxillofacial trauma. Both globes were luxated out of the orbit and suspended on the skin of the upper lid...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210501500119
更新日期：2005-01-01 00:00:00
abstract：PURPOSE:To present outcome data on low risk primary trabeculectomy augmented with low dose peroperative (0.1 mg/mL for 1 minute) mitomycin-C (MMC). METHODS:Retrospective case note review. All cases of trabeculectomy utilizing MMC augmentation at a concentration of 0.1 mg/mL with an application time of 1 minute and at ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：2009-11-01 00:00:00
abstract：PURPOSE:Ibopamine is a prodrug of N-methyldopamine that has a non-cycloplegic mydriatic action due to its alpha-adrenergic properties and is able to induce, when topically given, a transient increase of intraocular pressure (IOP) in eyes with hydrodynamic disorders. METHODS:This is a randomized, crossover, open-labele...
journal_title：European journal of ophthalmology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：2004-11-01 00:00:00
abstract：:The risk factors for intraoperative and early postoperative complications were evaluated in 351 consecutive cataract operations at the Oulu University Hospital in 1990. Bleeding into the anterior chamber during the operation was recorded in 8.6%, zonular rupture in 6.6%, posterior capsular rupture in 5.4% and vitreous...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：PURPOSE:To evaluate anterior chamber biometry of the eyes of normal children using ultrasound biomicroscopy (UBM) and to evaluate the differences in biometry between children and adults, and before and after pupil dilation in children. METHODS:Anterior chamber depth (ACD) and trabecular-iris angle (TIA) were measured ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210801800405
更新日期：2008-07-01 00:00:00
abstract：PURPOSE:This study aimed to investigate the role of protein peroxidation by detecting the serum levels of advanced oxidation protein products (AOPP), a novel marker for the degree of oxidative damage to proteins, and total thiol as a marker of antioxidant status in diabetic patients with or without diabetic retinopathy...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210801800521
更新日期：2008-09-01 00:00:00
abstract：PURPOSE:To describe the surgical interventions in congenital pupillary-iris-lens membrane. Six patients with congenital pupillary-iris-lens membrane presented with partial or totally occluded pupils, or increased intraocular pressure (IOP). METHODS:We describe the value of creating 2 paracenteses. The first one is mad...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/EJO.2011.7734
更新日期：2011-09-01 00:00:00
abstract：PURPOSE:To assess the intraoperative vaulting in patients undergoing implantable collamer lens (ICL) implantation with microscope-integrated intraoperative optical coherence tomography (iOCT) and correlate it with the postoperative vaulting. METHODS:Forty eyes of 22 consecutive patients undergoing ICL implantation wer...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000818
更新日期：2017-01-19 00:00:00
abstract：PURPOSE:To compare the clinical results of heparin surface modified (HSM) hydrophilic acrylic intraocular lens (IOL) with those of hydrophobic acrylic IOL. METHODS:One hundred patients with cataract were randomized to receive one of acrylic foldable IOLs after phacoemulsification: HSM hydrophilic acrylic IOL (n=50) Bi...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1177/112067210801800311
更新日期：2008-05-01 00:00:00
abstract：:The purpose of this study was to evaluate the hemodynamic changes occurring in the ophthalmic vasculature of eyes with Behçet's disease in a controlled clinical trial. Both eyes of patients with retinal involvement due to Behçet's disease were consecutively evaluated and were established as having mild or severe retin...
journal_title：European journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1997-07-01 00:00:00
abstract：PURPOSE:To describe a new genetic variation of BEST1 gene in Best vitelliform macular dystrophy. METHODS:A patient with bilateral multiple retinal yellowish lesions at the posterior pole underwent fluorescein angiography, fundus autofluorescence, optical coherence tomography, electrooculogram and blood sample for gene...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120920536
更新日期：2020-04-22 00:00:00
abstract：PURPOSE:The authors report the ophthalmic characteristics of a male proband in a Japanese family with autosomal dominant optic atrophy (DOA) harboring a frameshift mutation in the OPA1 gene. METHODS:Conventional ophthalmologic examinations including static automated perimetry were performed, as well as assessment of t...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210701700216
更新日期：2007-03-01 00:00:00
