Abstract:
PURPOSE:To report the laboratory findings, management strategies, and visual outcomes of culture-proven exogenous fungal endophthalmitis in North China. METHODS:The microbiological and treatment records of patients with culture-positive exogenous fungal endophthalmitis who visited the Affiliated Hospital of Qingdao University from January 2012 to December 2016 were reviewed. RESULTS:A total of 39 eyes (39 patients) were identified over a 5-year period. Exogenous fungal endophthalmitis was associated with penetrating trauma in 22 eyes (56.4%), fungal keratitis in 15 eyes (38.5%), and intraocular surgery in 2 eyes (5.1%). Hyphae were found in 29 of 37 smear samples (78.4%) by direct microscopic examination. Fungal pathogens cultured from 39 samples were identified as 10 genera and 15 species. Filamentous fungi (molds) accounted for 94.9% (37 samples), including Fusarium (19, 48.7%) and Aspergillus (11, 28.2%). Most keratitis cases were caused by Fusarium (11 of 15; 73.3 %). Aspergillus was isolated from nine penetrating ocular trauma cases (9 of 22; 40.9%). Three eyes receiving evisceration had fungal and bacteria coinfection (3 of 39, 7.7%) with Aspergillus and Bacillus. At least, one surgical intervention was performed in all 39 eyes and 28 (71.8%) eyes underwent two or more procedures, including surgeries and intraocular injections. Twenty-nine patients received intraocular antifungal therapy with amphotericin B and/or voriconazole. Visual acuity at discharge from the hospital was significantly better than the initial visual acuity (p < 0.001). Final vision of 20/400 or better was achieved in 22 (56.4%) eyes. CONCLUSIONS:This study highlighted the differences between clinical categories of exogenous fungal endophthalmitis. Trauma was the major etiological factor. Molds were the most common pathogens, with Fusarium ranking first, followed by Aspergillus. Fungal and bacterial coinfection mostly occurred after metal penetrating trauma, and Bacillus was the primary bacterial pathogen. Coinfection may be one reason of evisceration. Immediate intravitreal antifungal therapy combined with vitrectomy was effective for exogenous fungal endophthalmitis. Amphotericin B and voriconazole were commonly used antifungal agents.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Liu MY,Zhang L,Yin XL,Sun SYdoi
10.1177/1120672119833896subject
Has Abstractpub_date
2020-05-01 00:00:00pages
455-461issue
3eissn
1120-6721issn
1724-6016journal_volume
30pub_type
杂志文章abstract:PURPOSE:To present a case of ocular decompression retinopathy occurring after an uncomplicated nonpenetrating glaucoma procedure (deep sclerectomy with mitomycin C). METHODS:A 52-year-old man with medically uncontrolled exfoliation glaucoma in the left eye underwent uneventful deep sclerectomy with mitomycin C. The pa...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2010.5731
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:To determine agreement between peripapillary retinal nerve fiber layer (RNFL) thickness measurements by 2 spectral domain optical coherence tomography (SD-OCT) instruments. METHODS:. This was an observational, cross-sectional study. Both eyes of 89 subjects, 44 healthy subjects (mean age, 47±15 years) and 45 ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000167
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:To report a case of presumed bilateral acute retinal necrosis with delayed onset caused by herpes simplex virus type 2, medical treatment, and surgical approach. METHODS:Retrospective, interventional case described in a 51-year-old patient who complained of unilateral blurred vision with history of nonoperated...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000596
更新日期:2015-07-30 00:00:00
abstract:PURPOSE:To report three cases of bilateral primary choroidal melanoma treated with bilateral plaque radiotherapy. METHODS:Retrospective, single-center case series. RESULTS:Case 1: In 1981, a 50-year-old man was diagnosed with a 5-mm-thick choroidal melanoma in the right eye (OD) and treated with plaque radiotherapy. ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210601600619
更新日期:2006-11-01 00:00:00
abstract::In 1958, Kearns and Sayre described a multisystem entity, now known as Kearns-Sayre syndrome (KSS). The syndrome is defined as exhibiting a triad of thus far unexplained degenerative conditions: progressive external ophthalmoplegia, retinal pigmentary degeneration, and heart block. Commonly accompanying findings inclu...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:To quantify the maximal level of temperature and the time the maximal temperature is achieved and correlate the temperature parameters to the mean rate of endothelial cell loss after standardized ultrasound delivery assisted with four viscoelastic substances or different temperature of balanced salt solution (B...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2005-11-01 00:00:00
abstract:PURPOSE:To determine the incidence, timing and risk factors for glaucoma and visual axis opacification development following surgery for congenital cataract in the first year of life. METHODS:A prospective case series of all cataract surgery performed in Temple Street Children's University Hospital over a 28-year peri...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119862878
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To report a case of recurrent cytomegalovirus (CMV) corneal endotheliitis after penetrating keratoplasty. METHODS:Penetrating keratoplasty (PK) was performed in a 49-year-old man with bullous keratopathy. Pigmented keratic precipitates (KPs) were found in the corneal endothelium of the graft 13 days after surg...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000231
更新日期:2010-03-01 00:00:00
abstract:PURPOSE:To investigate visual function and ocular features in children with attention deficit hyperactivity disorder (ADHD). METHODS:Fifty-one children underwent a detailed ophthalmologic evaluation. Thirty-two were diagnosed with ADHD, and 19 children with attention deficit disorder (ADD). The mean age was 9.9±3.1 ye...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000145
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:To investigate central corneal thickness (CCT) and intraocular pressure (IOP) relationship in eyes with and without previous corneal laser refractive surgery and to compare the estimates of two different tonometersGoldmann applanation and pneumatonometer. METHODS:The study population included 234 glaucoma susp...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.1534
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:Choroidal neovascularization (CNV) is a rare complication after laser photocoagulation for disorders such as central serous chorioretinopathy (CSC). METHODS:We report 2 patients who developed CNV after laser treatment for persistent CSC and were treated by 3 1.25-mg intravitreal injections of bevacizumab in 1-...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000036
更新日期:2012-05-01 00:00:00
abstract::The changes in the cardiovascular system are associated with ocular manifestations, often as a consequence of pathological alteration in the ocular vasculature. The ease of visualization of these retinal changes makes the eye a window to the cardiovascular system. Certain congenital cardiac defects lead to changes in ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1177/1120672120914232
更新日期:2020-11-01 00:00:00
abstract::Strabismus fixus is a rare condition and usually is of convergent type in which one or both eyes are anchored in a position of extreme adduction. Convergent type strabismus fixus is considered to be a congenital disorder and a part of congenital extraocular muscle fibrosis syndrome. Villasecca and Martinez described a...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210301300214
更新日期:2003-03-01 00:00:00
abstract:PURPOSE:To examine the association between Lp(a) concentrations and the severity of retinopathy in 22 younger-onset and 48 older-onset diabetic subjects from the Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR), a population-based study of diabetic retinopathy. METHODS:We used a subset of the WESDR popula...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract:BACKGROUND:Retinitis punctata albescens is a form of retinitis pigmentosa characterized by white fleck-like deposits in the fundus, in most cases caused by pathogenic variants in RLBP1 gene. The purpose of this work is to report the phenotypic and genotypic data of a patient with retinitis punctata albescens carrying a...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120919064
更新日期:2020-04-28 00:00:00
abstract:PURPOSE:To report a case of extreme corneal flattening after initially uneventful Descemet stripping endothelial keratoplasty (DSEK). METHODS:A 76-year-old man underwent uneventful DSEK for pseudophakic bullous keratopathy (PBK) in his left eye. Postoperative evaluations were performed using anterior segment optical c...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000658
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:To report the visual and refractive outcomes of sequential intracorneal ring segment (ICRS) and toric phakic intraocular lens (IOL) insertion for visual rehabilitation in keratoconus. METHODS:A retrospective interventional cohort study was performed through the Corneoplastics unit and Eye Bank, Queen Victoria ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120969600
更新日期:2020-11-02 00:00:00
abstract:PURPOSE:Leber hereditary optic neuropathy (LHON) is recognized as the most common cause of isolated blindness in young men. The current study was designed to test whether LHON as a mitochondrial disease is associated with vascular functional alterations characterized by aortic elastic properties during echocardiography...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800225
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:Brimonidine is a lowering pressure agent currently used in glaucoma. This chronic degenerative condition is characterised by neuronal death, and an agent which offers neuroprotection may slow down or impede the progression of neuronal cell death. METHODS:The effects of brimonidine (BMD) on the short- and long-...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.4056
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:To determine the microbial contamination of the irrigating fluids at the time of phacoemulsification after the use of topical povidone-iodine and antibiotics prophylaxis. METHODS:A total of 119 patients undergoing cataract surgery were enrolled in this prospective study. All patients received 5 mg/mL levofloxa...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.8434
更新日期:2012-03-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-10-01 00:00:00
abstract:PURPOSE:To compare the clinical results of heparin surface modified (HSM) hydrophilic acrylic intraocular lens (IOL) with those of hydrophobic acrylic IOL. METHODS:One hundred patients with cataract were randomized to receive one of acrylic foldable IOLs after phacoemulsification: HSM hydrophilic acrylic IOL (n=50) Bi...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1177/112067210801800311
更新日期:2008-05-01 00:00:00
abstract::To evaluate the present level of reliability of common ultrasonography prior to vitreoretinal surgery, we carried out a prospective study to compare preoperative ultrasonography data with direct intraoperative findings. A total of 228 eyes with different vitreoretinal disorders and opaque or clear media were studied. ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1994-04-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of inferior sutureless sclerotomies without subretinal fluid drainage for the treatment of bullous exudative retinal detachment secondary to diffuse retinal pigment epitheliopathy. METHODS:A retrospective interventional case series of eyes treated with two inferior postequatorial full-...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800618
更新日期:2008-11-01 00:00:00
abstract:PURPOSE:Hand, foot, and mouth disease is a contagious enteroviral infection occurring primarily in children and characterized by vesicular palmoplantar eruptions and erosive stomatitis. There are very few cases of unilateral acute idiopathic maculopathy associated with hand, foot, and mouth infection. We described a ca...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000288
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:To report clinical and confocal microscopy features of late-onset Candida albicans keratitis after Descemet stripping automated keratoplasty (DSAEK). METHODS:We performed clinical and confocal scan on a patient who underwent DSAEK and phacoemulsification for Fuchs endothelial dystrophy and cataract. RESULTS:A...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.6228
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Continuous subcutaneous insulin infusion (CSII) is a treatment for type 1 diabetes that improves metabolic control and reduces micro and macrovascular complications. The aim of this study was to compare the effect of CSII versus traditional multiple daily injections (MDI) therapy on retinal vascul...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672121990576
更新日期:2021-01-26 00:00:00
abstract:PURPOSE:The main purpose of this prospective study was to compare the efficacy, local tolerance, and safety of topical lomefloxacin 0.3% and topical ofloxacin 0.3% in the treatment of acute bacterial conjunctivitis. PATIENTS AND METHODS:Forty patients with acute bacterial conjunctivitis were included in a randomized, ...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1999-10-01 00:00:00
abstract::Bruch's membrane, an extracellular matrix located between the retinal pigment epithelium and the choroid, plays a vital role as structural and functional support to the retinal pigment epithelium. Dysfunction of Bruch's membrane in both age-related macular degeneration and other ocular diseases is caused mostly by ext...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1177/1120672120919337
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:In this article, we evaluate subfoveal choroidal thickness in celiac patients with respect to adherence to the gluten-free diet and nonadherence to the gluten-free diet, comparing with age and sex matched healthy controls using spectral-domain optical coherence tomography. MATERIALS AND METHODS:A case-control ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00