Abstract:
PURPOSE:This study aimed to investigate the role of protein peroxidation by detecting the serum levels of advanced oxidation protein products (AOPP), a novel marker for the degree of oxidative damage to proteins, and total thiol as a marker of antioxidant status in diabetic patients with or without diabetic retinopathy (DR) and to compare the results with those of control subjects. METHODS:The study groups consisted of two separate subgroups: 1) 37 patients (14 male, 23 female) with noninsulin-dependent diabetes mellitus (NIDDM) showing diabetic retinopathy (DR) and 2) 20 patients with NIDDM and without any signs of DR (9 male, 11 female); 26 healthy non-diabetic control subjects (15 male, 11 female) were selected from the patients attending our department for refractive disorders. Venous blood samples of all participants were collected in the morning after an overnight fast, and serum samples storedat -70 degrees C until assay for AOPP, and total thiol. RESULTS:AOPP levels were significantly higher in diabetic patients with (210.9+/-73.0 micronmol/L) or without DR (222.7+/-94.4 micronmol/L) when compared to those of controls (152.4+/-72.04 micronmol/L) (p=0.004). Even though the difference was not statistically significant (p=0.095), total thiol levels in cases with DR (278.7+/-139.1 micronmol/L) were lower than those without DR (334.0+/-129.4 micronmol/L) and controls (353.2+/-145.6 micronmol/L). Correlation tests did not reveal any association between these parameters and age, sex, or duration of DM. CONCLUSIONS:The present study suggests that increased protein oxidation may contribute to the pathogenesis of DR.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Baskol G,Gumus K,Oner A,Arda H,Karakucuk Sdoi
10.1177/112067210801800521subject
Has Abstractpub_date
2008-09-01 00:00:00pages
792-8issue
5eissn
1120-6721issn
1724-6016journal_volume
18pub_type
杂志文章abstract:OBJECTIVE:To assess the role of 10-2 visual field (VF) test in different stages of glaucoma. METHODS:In our prospective comparative study, 24-2 and 10-2 VF tests were done for 115 eyes with different stages of glaucomatous damage or glaucoma suspects. Optical coherence tomography (OCT) was performed in 79 eyes. We com...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119836904
更新日期:2020-07-01 00:00:00
abstract:PURPOSE:The convergence excess esotropia (CEET) is defined when near esotropia is greater than the distance by at least 10 PD while the eye is corrected with the full cycloplegic refraction. The purpose of this study is to evaluate the effect of a modified technique of Y- split recession of the medial rectus muscles on...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120965494
更新日期:2020-10-23 00:00:00
abstract:PURPOSE:To examine the nature and frequency of ocular side effects due to systemic target therapy with BRAF and MEK inhibitors as well as immunotherapy with cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed cell death 1 (PD-1) monoclonal antibodies used in the treatment of cutaneous malignant melanoma (CMM). DE...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120930688
更新日期:2020-05-31 00:00:00
abstract:PURPOSE:This study deals with the role of the topical administration of dorzolamide eyedrops on the oxidative/antioxidant status of aqueous humor in patients with primary open angle glaucoma (POAG). METHODS:A case-control study including 130 patients distributed into three groups was carried out: 1) patients with POAG...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210901900408
更新日期:2009-07-01 00:00:00
abstract::not available. ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.1196
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:To study the short-term effects of intravitreal bevacizumab (Avastin) on retinal blood flow velocity and compare them to clinical outcomes assessed by optical coherence tomography (OCT) and tests of visual acuity. METHODS:The Retinal Function Imager (RFI) was used noninvasively and quantitatively to measure re...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000074
更新日期:2012-05-01 00:00:00
abstract:PURPOSE:To illustrate the successful outcome of pars plana vitrectomy (PPV) with melphalan irrigation for vitreous hemorrhage (VH) with suspected viable retinoblastoma. Despite the high risk of intraocular surgery, it was performed to preserve the only potentially seeing eye with treated retinoblastoma. METHODS:Vitreo...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000683
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:To describe a case of a 46-year-old woman with an asymptomatic history of unilateral multiple serous detachments of the retinal pigment epithelium (PED) in the right eye, treated with photodynamic therapy (PDT) with verteporfin for recent onset of subfoveal choroidal neovascularization (CNV) with chorioretinal ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract:PURPOSE:To describe a technique for suturing a luxated intraocular lens (IOL) in the vitreous cavity directly to the ciliary sulcus using intraocular slipknot without IOL extraction. DESIGN:Noncomparative interventional case series. MATERIALS AND METHODS:A three-port vitrectomy was performed in all cases. According t...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210301300604
更新日期:2003-07-01 00:00:00
abstract:PURPOSE:This study was conducted in 2002-2003 at selected schools of eight health regions of Oman. The authors present risk factors and predictors of progression of myopia between the 7th and 10th grades. METHODS:This was a historical cohort study. A total of 1304 students in 10th grade, both with and without progress...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700115
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:To describe the use of silicone oil (SO) in combination with subretinal recombinant tissue plasminogen activator (rtPA) to achieve dislocation of large subretinal hemorrhage secondary to exudative age-related macular degeneration (AMD). METHODS:A single-eye 81-year-old woman, known for exudative AMD, presented...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120952349
更新日期:2020-08-18 00:00:00
abstract:PURPOSE:To evaluate the role of postoperative prone posturing for a single night in the outcome of trans pars plana vitrectomy (TPPV) with internal limiting membrane (ILM) peel and 20% perfluoroethane (C2F6) internal tamponade for idiopathic macular hole. METHODS:This prospective trial enrolled 14 eyes in 14 consecuti...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000039
更新日期:2012-05-01 00:00:00
abstract:PURPOSE:To evaluate the intraocular pressure-lowering effect, the safety profile, and the success rate of the XEN45 Gel Stent (Allergan, Dublin, Ireland) in patients with pseudoexfoliative glaucoma. METHODS:Retrospective study conducted on patients with pseudoexfoliative glaucoma, with or without cataract, who underwe...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672118795063
更新日期:2019-05-01 00:00:00
abstract:PURPOSE:To compare 4 limbal-conjunctival autograft fixation techniques-conventional suture, commercial fibrin glue, autologous fibrin glue, and cautery-in primary nasal pterygium surgery. METHODS:This is a retrospective and descriptive study. The postoperative patient discomfort, graft edema, ocular inflammation, and ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000924
更新日期:2017-06-26 00:00:00
abstract:OBJECTIVE:To investigate the systemic associations of central serous chorioretinopathy (CSCR) with help of clinical and biochemical investigations. DESIGN:Case-control study. PARTICIPANTS:Eighty seven CSCR patients (case) and 82 Asian-Indian patients with primary non-traumatic rhegmatogenous retinal detachment (contr...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120975698
更新日期:2020-11-25 00:00:00
abstract:PURPOSE:To report an unusual complication of treatment in the case of a Descemets membrane detachment. METHODS:Observational case report. RESULTS:A 79-year-old woman presented for elective cataract surgery. Ocular risk factors identified preoperatively included moderately shallow anterior chambers bilaterally, previo...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.5031
更新日期:2006-09-01 00:00:00
abstract:PURPOSE:Leber hereditary optic neuropathy (LHON) is recognized as the most common cause of isolated blindness in young men. The current study was designed to test whether LHON as a mitochondrial disease is associated with vascular functional alterations characterized by aortic elastic properties during echocardiography...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800225
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:To compare the performance of two different microcatheter systems, iTrack™ 250A and Glaucolight, in ab externo canaloplasty in three major categories: intraocular pressure reduction, drug therapy reintroduction, and evaluation of viscodilation over distension of the inner wall of Schlemm's canal. METHODS:A tot...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119833547
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:We aimed to discuss the possible role of developmental embryologic factors in neural crest cells in the aetiology of keratoconus and Fuchs' heterochromic iridocyclitis by presenting this case. CASE REPORT:We diagnosed bilateral keratoconus and unilateral Fuchs' heterochromic iridocyclitis in a 19 year old wome...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100114
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:To report a real-life experience with the Argus II retinal prosthesis system in blind patients with end-stage retinitis pigmentosa (RP) or choroideremia (CHM), focusing on the pivotal role of optical coherence tomography (OCT) in both preoperative and postoperative management. METHODS:This hospital-based case ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000852
更新日期:2017-01-19 00:00:00
abstract:PURPOSE:Parry-Romberg syndrome (PRS) is a rare disease of unknown etiology and pathogenesis, characterized by progressive hemifacial atrophy. Diverse ocular manifestations were reported in association with PRS, including enophthalmos, lid retraction, blepharoptosis, restrictive strabismus, ocular motor nerve dysfunctio...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000132
更新日期:2010-01-01 00:00:00
abstract::In renal failure the incidence of pingueculae is significantly higher than in a comparable control group but there is no evidence that the calcific precipitation in renal failure is of a dystrophic nature. The lime salts are not located within the area of elastotic degeneration, a prerequisite for dystrophic degenerat...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of intravitreal dexamethasone implant in treatment naïve eyes with diabetic macular edema (DME). METHODS:A retrospective analysis of treatment naïve eyes with DME which received intravitreal dexamethasone implant between January 2016 and March 2018 was done. Demographic deta...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120949761
更新日期:2020-08-10 00:00:00
abstract:PURPOSE:To report the visual and refractive outcomes of sequential intracorneal ring segment (ICRS) and toric phakic intraocular lens (IOL) insertion for visual rehabilitation in keratoconus. METHODS:A retrospective interventional cohort study was performed through the Corneoplastics unit and Eye Bank, Queen Victoria ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120969600
更新日期:2020-11-02 00:00:00
abstract:PURPOSE:To assess the long-term results of viscotrabeculotomy in infants with primary congenital glaucoma and to compare its outcome with conventional trabeculotomy. PATIENTS AND METHODS:A prospective randomized comparative study included infants with primary congenital glaucoma younger than 2 years. Patients were div...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120922453
更新日期:2020-05-26 00:00:00
abstract:PURPOSE:To evaluate changes in anterior chamber morphology with the Pentacam anterior segment analyzer and gonioscopy after laser peripheral iridotomy (LPI) in patients with primary angle closure glaucoma and narrow angle and to compare central corneal thickness measurements performed with Pentacam and ultrasound pachy...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000211
更新日期:2010-03-01 00:00:00
abstract:PURPOSE:To describe the visual phenotype of multiple sclerosis (MS) in the Afro-Caribbean population living in Martinique (French West Indies) and to specify the influence of the migration to metropolitan France on ocular impairment. DESIGN:Prospective consecutive observational case series. METHODS:A complete ophthal...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210501500313
更新日期:2005-05-01 00:00:00
abstract:PURPOSE:To report a case of bilateral retinocytoma associated with calcified vitreous deposits. METHODS:Case report. RESULTS:On routine examination, a 35-year-old asymptomatic father of a child with bilateral retinoblastoma presented bilateral retinocytoma associated with vitreous calcifications, in the vicinity of t...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210601600227
更新日期:2006-03-01 00:00:00
abstract:PURPOSE:To report a case of monolateral preretinal fibrovascularproliferations in a young adult woman, who had suffered from incontinentia pigmenti (IP) during her first month of life. METHODS:Case report. RESULTS:Circumscribed preretinal fibrovascular proliferations, adjacent to a mid-peripheral area of snail track ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210201200418
更新日期:2002-07-01 00:00:00
abstract:PURPOSE:The main purpose of this prospective study was to compare the efficacy, local tolerance, and safety of topical lomefloxacin 0.3% and topical ofloxacin 0.3% in the treatment of acute bacterial conjunctivitis. PATIENTS AND METHODS:Forty patients with acute bacterial conjunctivitis were included in a randomized, ...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1999-10-01 00:00:00