Abstract:
:Blood flow in various tissues of the body shows spontaneous variations. The purpose of this study was to analyze variations over time in the blood flow of the optic nerve head. Blood flow was measured by the laser Doppler flowmeter (LDF) in 12 healthy volunteers, and analyzed by spectral Fourier analysis. The LDF technique allows continuous measurement of flow, volume, and velocity in the microcirculation of the optic nerve head. We found variations expressed in cycles per minute (c/min) at frequencies characteristic of vasomotion (< 10 c/min) of breathing, and of cardiac pulsation. Oscillations at frequency < 10 c/min predominated in volume in all subjects and in flow in all but one. Variations in velocity of 60-90 c/min were identified in 10 of the 12 volunteers. Oscillations in the range of breathing frequency made the smallest contribution to changes in blood flow. Fluctuations in the frequency range of 5 c/min and lower were observed most frequently, and the majority of subjects showed fluctuations of several frequencies. Our results provide evidence that blood flow in the human optic nerve head presents some characteristics already known from the general physiology of the microcirculation.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Osuský R,Schoetzau A,Flammer Jsubject
Has Abstractpub_date
1997-10-01 00:00:00pages
364-9issue
4eissn
1120-6721issn
1724-6016journal_volume
7pub_type
杂志文章abstract:PURPOSE:To describe the unusual complication of retinal pigment epithelial (RPE) tear after intravitreal ranibizumab (Lucentis) for subfoveal fibrovascular pigment epithelial detachment (PED) and its effective management. METHODS:Chart review for case report of RPE tear after ranibizumab. RESULTS:An inferior RPE tear...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700432
更新日期:2007-07-01 00:00:00
abstract:PURPOSE:To calculate the reliability of an eye-dedicated triaging system named Rome Eye Scoring System for Urgency and Emergency (RESCUE). METHODS:There were four coding parameters: pain, redness, loss of vision, and risk of open globe. Each parameter is assigned a score, the sum of which allows color coding. There we...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800321
更新日期:2008-05-01 00:00:00
abstract:PURPOSE:To delineate and discuss a not yet described possible ocular complication of selective intra-arterial chemotherapy (SIAC) for treatment of retinoblastoma. METHODS:A 23-month-old girl with a large unilateral retinoblastoma was treated with repeated SIAC using 5 mg melphalan between July 2010 and January 2012. C...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000393
更新日期:2014-05-01 00:00:00
abstract:PURPOSE:To report a case of bilateral non-simultaneous optic neuropathy and unilateral macular edema in a patient with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome. METHODS:A 61-year-old man with POEMS syndrome had bilateral anterior optic neuropathy and unilat...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210901900129
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:To report a case of monolateral preretinal fibrovascularproliferations in a young adult woman, who had suffered from incontinentia pigmenti (IP) during her first month of life. METHODS:Case report. RESULTS:Circumscribed preretinal fibrovascular proliferations, adjacent to a mid-peripheral area of snail track ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210201200418
更新日期:2002-07-01 00:00:00
abstract:INTRODUCTION:The aim of this study was to evaluate repeatability and reproducibility of newly calculated biomechanical parameters of the cornea, developed by our research group. METHODS:One eye from each of the 23 healthy subjects was measured three times consecutively, three times at different daytimes and on three d...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119864554
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To review and analyze the epidemiological profile, clinical characteristics and visual outcomes in patients attended for traumatic open globe injury (OGI) at our hospital over a 5-year period. DESIGN:Retrospective chart review study. METHODS:Retrospective analysis of all patients attended at Fundación Jiménez...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120962039
更新日期:2020-10-10 00:00:00
abstract:PURPOSE:Among the 500 ABCA4 mutations identified so far in the retina-specific ABC transporter (ABCA4) gene, only 20 have been described in patients with autosomal recessive retinitis pigmentosa (arRP). In this study the gene was screened for mutations in a cohort of 25 patients of Spanish origin, to further assess ABC...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700510
更新日期:2007-09-01 00:00:00
abstract::This work was inspired by a recent juridical development in Italy, whose purpose is to prevent rejection of damage claims whenever it is not possible to prove a causal link between iatrogenic illicit behavior and damage to the patient, despite the fact that the patient has clearly suffered physical or mental injury. I...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2010.6211
更新日期:2011-05-01 00:00:00
abstract:PURPOSE:To report a case of tubulointerstitial nephritis and uveitis syndrome (TINU syndrome) with unusual unilateral neuroretinitis. METHODS:An 11-year-old girl who developed anterior uveitis 3 months after acute tubulointerstitial nephritis, without any etiologic factors for either nephritis or uveitis, is presented...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2004-07-01 00:00:00
abstract:PURPOSE:To describe the surgical interventions in congenital pupillary-iris-lens membrane. Six patients with congenital pupillary-iris-lens membrane presented with partial or totally occluded pupils, or increased intraocular pressure (IOP). METHODS:We describe the value of creating 2 paracenteses. The first one is mad...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.7734
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To evaluate the long-term results of pars plana vitrectomy (PPV) and silicone oil implantation (SOI) for giant retinal tears (GT). METHODS:PPV with SOI was performed for GT in 50 eyes of 46 patients. Thirty-one eyes (62%) of 27 patients suffered from idiopathic GT. A direct injury of the eye preceded GT in 19 ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of intravitreal dexamethasone implant in treatment naïve eyes with diabetic macular edema (DME). METHODS:A retrospective analysis of treatment naïve eyes with DME which received intravitreal dexamethasone implant between January 2016 and March 2018 was done. Demographic deta...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120949761
更新日期:2020-08-10 00:00:00
abstract:PURPOSE:To illustrate the successful outcome of pars plana vitrectomy (PPV) with melphalan irrigation for vitreous hemorrhage (VH) with suspected viable retinoblastoma. Despite the high risk of intraocular surgery, it was performed to preserve the only potentially seeing eye with treated retinoblastoma. METHODS:Vitreo...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000683
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:To investigate central corneal thickness (CCT) and intraocular pressure (IOP) relationship in eyes with and without previous corneal laser refractive surgery and to compare the estimates of two different tonometersGoldmann applanation and pneumatonometer. METHODS:The study population included 234 glaucoma susp...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.1534
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To evaluate rotational stability, astigmatism correction, visual outcomes, and patient satisfaction after implantation of the toric intraocular lens (IOL) Torica-aA following cataract extraction over a 6-month follow-up period. METHODS:This prospective observational study enrolled 40 eyes of 26 patients presen...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000696
更新日期:2016-06-10 00:00:00
abstract:PURPOSE:Characterize the safety and tolerability of lifitegrast ophthalmic solution 5.0% for the treatment of dry eye disease. METHODS:Pooled data from five randomized controlled trials were analyzed. Key inclusion criteria were adults with dry eye disease (Schirmer tear test score ⩾1 and ⩽10 mm, eye dryness score ⩾40...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/1120672118791936
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Continuous subcutaneous insulin infusion (CSII) is a treatment for type 1 diabetes that improves metabolic control and reduces micro and macrovascular complications. The aim of this study was to compare the effect of CSII versus traditional multiple daily injections (MDI) therapy on retinal vascul...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672121990576
更新日期:2021-01-26 00:00:00
abstract:PURPOSE:To evaluate the additional therapeutic effect of single intravitreal bevacizumab injection on standard laser treatment in the management of proliferative diabetic retinopathy. METHODS:A prospective, fellow-eye sham controlled clinical trial was conducted on 80 eyes of 40 high-risk characteristic proliferative ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1177/112067210801800215
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:To report on the efficacy and safety of combined phacoemulsification and an Ahmed valve glaucoma drainage implant with respect to visual acuity improvement, intraocular pressure (IOP) control, and requirement for antiglaucoma medication. METHODS:A retrospective chart review was conducted of 41 eyes (31 patient...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800205
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:To report a case of extreme corneal flattening after initially uneventful Descemet stripping endothelial keratoplasty (DSEK). METHODS:A 76-year-old man underwent uneventful DSEK for pseudophakic bullous keratopathy (PBK) in his left eye. Postoperative evaluations were performed using anterior segment optical c...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000658
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:To prospectively compare the clinical results of two cataract surgery procedures through a 4.0-mm incision, differing only in the wound location (superior or lateral). METHODS:168 eyes with cataract were randomly assigned to either procedure. Except for incision location, surgical methods were identical. Uncor...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-10-01 00:00:00
abstract:PURPOSE:To look for ophthalmologic abnormalities in 15 patients with Wolfram syndrome, also known as DIDMOAD syndrome (diabetes insipidus, diabetes mellitus, optic atrophy and deafness). METHODS:Fifteen patients from four inbred families diagnosed as having Wolfram syndrome at the National Center for Diabetes, Endocri...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210201200202
更新日期:2002-03-01 00:00:00
abstract:PURPOSE:To evaluate the ability of scanning laser polarimetry (SLP) with a fixed corneal polarization compensator (GDx-FCC Nerve Fiber Analyzer) compared to one with a variable one (GDx-VCC) in the discrimination between healthy and early glaucomatous eyes. METHODS:Forty patients with early glaucomatous visual field d...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210501500409
更新日期:2005-07-01 00:00:00
abstract:PURPOSE:Pterygium is an invasive and highly vascularized growth, thought to arise from activated and proliferating limbal epithelial stem cells. Epidemiologic studies have found the increase of active angiogenic and epithelial growth factors in pterygia, and implicated that these molecules could be involved directly or...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800104
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:To investigate the efficacy of intravitreal dexamethasone implants (DEX) after anti-VEGF failure in retinal vein occlusion macular oedema. METHODS:Retrospective cohort study of DEX implant (0.7 mg) given after anti-VEGF 'failure'. Switch to DEX occurred if a ⩽ +5 ETDRS letter gain and ⩽20% reduction in central...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120978355
更新日期:2020-12-27 00:00:00
abstract::Most cases of retinoblastoma are diagnosed before the age of 5 years. The cases in older age groups can have variable presentations leading to misdiagnosis and management challenges. We report a case of retinoblastoma in an 8-year-old female who was primarily referred as a case of sympathetic ophthalmia due to a co-in...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120939388
更新日期:2020-07-02 00:00:00
abstract:PURPOSE:Two cases with optic disc pit associated maculopathy, treated with vitrectomy surgery with internal limiting membrane peeling (ILM) and gas tamponade, are presented. METHODS:Interventional case reports. RESULTS:Two patients with serous macular detachment associated with a congenital optic pit underwent vitrec...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210901900230
更新日期:2009-03-01 00:00:00
abstract:PURPOSE:To investigate the ocular and orbital complications observed in children treated for retinoblastoma. SUBJECTS AND METHODS:We retrospectively studied 73 children (39 boys, 34 girls) suffering from retinoblastoma. Thirty-six had bilateral tumor and 37 unilateral disease for a total of 109 eyes affected. The foll...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1998-04-01 00:00:00
abstract:PURPOSE:To describe a rare presentation of pituitary apoplexy as unilateral abducens nerve palsy demonstrating the various presentations of the condition. METHODS:Case report. RESULTS:A 48-year-old man presented with isolated right abducens nerve palsy. Magnetic resonance imaging showed a large pituitary macroadenoma...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000136
更新日期:2010-01-01 00:00:00