Abstract:
PURPOSE:Pterygium is an invasive and highly vascularized growth, thought to arise from activated and proliferating limbal epithelial stem cells. Epidemiologic studies have found the increase of active angiogenic and epithelial growth factors in pterygia, and implicated that these molecules could be involved directly or indirectly in the pathogenesis of pterygia as causative factors. The aim of this study was to investigate the association of polymorphisms of transforming growth factor (TGF) and vascular endothelial growth factor (VEGF) with pterygium. METHODS:A total of 133 pterygium patients and 105 volunteers without pterygium were enrolled in this study. Polymerase chain reaction based restriction fragment length polymorphism analysis was used to resolve the TGF-Beta1-509 and VEGF-460 genotypes. RESULTS:There was no significant difference in the allele frequency or genotype of TGF-Beta1-509 or VEGF-460 between total pterygium and the control group. No interaction between TGF-Beta1-509 and VEGF-460 was found either. CONCLUSIONS:These results indicate that TGF-Beta1-509 and VEGF-460 polymorphisms were not highly associated with the pathology of pterygium. However, it may still be worthwhile to continue to search for angiogenic gene polymorphisms in order to predict the development of pterygium.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Bau DT,Chiang CC,Tsai YY,Lee CC,Tsai Y,Lin CC,Tsai CH,Tsai FJdoi
10.1177/112067210801800104subject
Has Abstractpub_date
2008-01-01 00:00:00pages
21-6issue
1eissn
1120-6721issn
1724-6016journal_volume
18pub_type
杂志文章abstract:PURPOSE:To assess and investigate the relationship between diurnal variations in intraocular pressure (IOP) and biomechanical properties of cornea. METHODS:Sixty-two healthy volunteers were recruited. Corneal compensated IOP (IOPcc), Goldmann-correlated IOP (IOPg), corneal resistance factor (CRF), and corneal hysteres...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210901900518
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:The study was conducted to assess the central corneal thickness (CCT) of the healthy cornea with a recently developed noncontact specular microscope (EM-3000; Tomey) and compare the results with those measured with a contact specular microscope and an ultrasound pachymeter. Agreement between measurements taken ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000504
更新日期:2010-09-01 00:00:00
abstract:PURPOSE:The purpose of this study was to assess indications and outcome of carotid Doppler ultrasound requested by ophthalmologists from an eye hospital over a period of three years. METHODS:This retrospective study was designed to analyse data for all patients referred to have carotid Doppler ultrasound from 1999 to ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00
abstract:PURPOSE:This study aimed to investigate the role of protein peroxidation by detecting the serum levels of advanced oxidation protein products (AOPP), a novel marker for the degree of oxidative damage to proteins, and total thiol as a marker of antioxidant status in diabetic patients with or without diabetic retinopathy...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800521
更新日期:2008-09-01 00:00:00
abstract:PURPOSE:To assess the role of risk factors for amblyopia, such as family history and neonatal background, for the prediction of either strabismic amblyopia or refractive amblyopia. METHODS:In this retrospective case-control model, the study population included all children born at the Hospital de Braga during 1997-201...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5001036
更新日期:2018-03-01 00:00:00
abstract:SIGNIFICANCE:Susac's syndrome is a rare retinocochleocerebral immune-mediated endotheliopathy and clinically manifests as a pathognomonic triad of encephalopathy, hearing loss, and branch retinal artery occlusion. This triad is rarely present at symptom onset, thus, it is often initially misdiagnosed. To date, Susac's ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120924545
更新日期:2020-05-07 00:00:00
abstract:PURPOSE::To describe the patterns of regression of choroidal melanoma after treatment with plaque brachytherapy. METHODS::Retrospective interventional case series including 170 consecutive patients treated with 103Pd eye plaque radiation for choroidal melanoma. Outcome measures were changes in tumor thickness, surface...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672118776146
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:Characterize the safety and tolerability of lifitegrast ophthalmic solution 5.0% for the treatment of dry eye disease. METHODS:Pooled data from five randomized controlled trials were analyzed. Key inclusion criteria were adults with dry eye disease (Schirmer tear test score ⩾1 and ⩽10 mm, eye dryness score ⩾40...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/1120672118791936
更新日期:2019-07-01 00:00:00
abstract::In 1958, Kearns and Sayre described a multisystem entity, now known as Kearns-Sayre syndrome (KSS). The syndrome is defined as exhibiting a triad of thus far unexplained degenerative conditions: progressive external ophthalmoplegia, retinal pigmentary degeneration, and heart block. Commonly accompanying findings inclu...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:The present study compared the expression of brain-derived neurotrophic factor (BDNF) in the lateral geniculate body between form deprivation amblyopia kittens and normal kittens to examine the significance of BDNF in the lateral geniculate body in the pathogenesis of amblyopia. METHODS:Twenty kittens were div...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120953341
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To compare lateral rectus recession (LRc) and medial rectus advancement (MRadv) for correction of consecutive exotropia (CXT). METHODS:Of the 43 exotropic patients 20 of them underwent LRc (group 1) and 23 of them underwent MRadv (group 2). Postoperative exodrift, strabismic angle, dose effect relationship wer...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120983199
更新日期:2021-01-09 00:00:00
abstract:PURPOSE:To compare retinal nerve fiber layer thickness (RNFLT) and inner macula thickness changes measured with Fourier-domain optical coherence tomography (FD-OCT) and scanning laser polarimetry during the course of acute optic neuritis (ON). METHODS:Nine eyes of 7 consecutive patients with multiple sclerosis (MS) we...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2010.5844
更新日期:2011-07-01 00:00:00
abstract:PURPOSE:The aim of this study is to assess the agreement between manual and automated gonioscopy for iridocorneal angle opening. METHODS:The research is a cross-sectional observational study. Manual and automated gonioscopy were performed to consecutive patients in a glaucoma clinic. Iridocorneal angle opening grading...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672118806436
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:Ibopamine is a prodrug of N-methyldopamine that has a non-cycloplegic mydriatic action due to its alpha-adrenergic properties and is able to induce, when topically given, a transient increase of intraocular pressure (IOP) in eyes with hydrodynamic disorders. METHODS:This is a randomized, crossover, open-labele...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:2004-11-01 00:00:00
abstract::This prospective study of 123 patients undergoing cataract extraction determined the preoperative and surgical factors predisposing to an exaggerated postoperative inflammatory response. It is important to identify the patients at increased risk of complications requiring additional prophylaxis or more intensive posto...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:To study the functional results of macular surgery and determine pre-operative features associated with better final visual outcome. METHODS:Forty-two consecutive patients underwent surgical removal of subfoveal choroidal neovascularization (CNV), related to age-related macular degeneration (AMD) in 8 eyes, de...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100313
更新日期:2001-07-01 00:00:00
abstract:PURPOSE:Good binocular potential has been a fundamental defining characteristic of acute acquired concomitant esotropia (AACE) type II. The purpose of this study was to ascertain the clinical features and surgical outcome in children with AACE type II who underwent repeated surgery for the sake of binocularity. METHOD...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000301
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:To evaluate the use of the resorbable polylactic acid polymer implants (Resorb X) in the management of orbital floor blow-out fractures as regards safety, cosmetic, and functional results. METHODS:In a prospective, interventional case series, 22 patients with traumatic blow-out floor fractures underwent lower ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120928005
更新日期:2020-05-31 00:00:00
abstract:PURPOSE:To present outcome data on low risk primary trabeculectomy augmented with low dose peroperative (0.1 mg/mL for 1 minute) mitomycin-C (MMC). METHODS:Retrospective case note review. All cases of trabeculectomy utilizing MMC augmentation at a concentration of 0.1 mg/mL with an application time of 1 minute and at ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2009-11-01 00:00:00
abstract:PURPOSE:To investigate the early neurodegenerative changes of inner retina and choroid in type 1 and type 2 diabetic patients without retinopathy and with early-stage retinopathy. METHODS:In this observational cross-sectional study, 90 right eyes of 90 naive type 1 and 2 diabetic patients without diabetic retinopathy ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000887
更新日期:2017-05-11 00:00:00
abstract::The purpose of this study was to evaluate the hemodynamic changes occurring in the ophthalmic vasculature of eyes with Behçet's disease in a controlled clinical trial. Both eyes of patients with retinal involvement due to Behçet's disease were consecutively evaluated and were established as having mild or severe retin...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1997-07-01 00:00:00
abstract:PURPOSE:Timely screening of premature babies is an important initial step in the management of retinopathy of prematurity (ROP) as earlier treatment results in improved visual prognosis. Screening criteria for ROP currently recommended by the American Academy of Pediatrics may not be applicable in developing countries....
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000417
更新日期:2010-07-01 00:00:00
abstract:PURPOSE:To verify the diagnostic value of closed chamber thermometry and humidity measurement in normal and dry eye patients. METHODS:In 20 patients (40 eyes) with dry eye and 20 normal sex- and age-matched controls (40 eyes), aged from 11 to 61 years (mean 37.52 yrs, standard deviation, (SD) 14.81) temperature was me...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210301300403
更新日期:2003-05-01 00:00:00
abstract:PURPOSE:To compare between mitomycin C alone, porcine extracellular matrix alone, and combined low dose mitomycin C with porcine extracellular matrix in term of efficacy and safety in phaco-trabeculectomy surgery. STUDY DESIGN:Prospective comparative. METHODS:Sixty eyes of 60 patients complaining of primary open angl...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120944339
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:To review methods of assessing bulbar redness, particularly with respect to the practicality of comparing different rating systems. METHODS:The published literature was reviewed and discussed by a panel of experts and a narrative review prepared. RESULTS:Bulbar hyperemia is a common clinical sign and an impor...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.5301/ejo.5000626
更新日期:2015-07-01 00:00:00
abstract:INTRODUCTION:Preretinal hemorrhages can be located in subhyaloid or sub-internal limiting membrane (ILM) space. Though optical coherence tomography (OCT) may help to distinguish the exact location of hemorrhage in selected cases, it is often difficult to discern clinically. The purpose is to describe a novel clinical s...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120934958
更新日期:2020-06-22 00:00:00
abstract:PURPOSE:To study the correlation between final visual acuity after successful anatomic macular hole repair and features on spectral domain optical coherence tomography (SD-OCT). METHODS:Retrospective review of charts of patients who underwent macular hole surgery. Data collection included pre- and postoperative best-c...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000306
更新日期:2010-05-01 00:00:00
abstract:PURPOSE:To present the results of a retrospective comparative unicentric institutional study of the incidence of postcataract surgery endophthalmitis before and after the introduction of the European Society of Cataract and Refractive Surgeons (ESCRS) protocol in 2007 in our department. METHODS:This study included 15,...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000417
更新日期:2014-07-01 00:00:00
abstract:INTRODUCTION:To identify novel velocity waveform parameters of the ophthalmic artery and central retinal artery by computer-aided image processing of Doppler ultrasonography measurements, and to evaluate correlations between the waveform parameters and different demographics and disease severity of open-angle glaucoma ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119848259
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:The purpose of this paper is to demonstrate a case of bilateral complete avulsion of the globes following maxillofacial trauma. METHODS:A 23-year-old man with bilateral complete globe avulsion following a maxillofacial trauma. Both globes were luxated out of the orbit and suspended on the skin of the upper lid...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210501500119
更新日期:2005-01-01 00:00:00