Abstract:
PURPOSE:To evaluate the efficacy and safety of needle revision and examine factors predictive of failure. METHODS:In total, 157 eyes of 131 patients that underwent needle revision augmented with either 5-fluorouracil or betamethasone for trabeculectomy failure were included in this retrospective study. Complete failure was defined as additional glaucoma surgery, ciliodestructive procedures, loss of light perception, sight-threatening complications, hypotony maculopathy, and surgical bleb revision. Success was defined as intraocular pressure ⩽ 18 (criterion A), ⩽15 (criterion B), and ⩽12 mmHg (criterion C) reached with (qualified) or without (complete) medications, and absence of any criteria of complete failure. RESULTS:The median (interquartile range) follow-up was 25.0 (41.0) months. Complete failure rates were 19%, 26%, and 31% at 1, 2, and 3 years, respectively. For criterion A, qualified and complete success rates were, respectively, 77% and 69% at 1 year, 66% and 51% at 2 years, and 60% and 47% at 3 years. For criterion B, qualified and complete success rates were, respectively, 67% and 61% at 1 year, 48% and 42% at 2 years, and 44% and 39% at 3 years. For criterion C, qualified and complete success rates were, respectively, 43% and 41% at 1 year, 27% and 25% at 2 years, and 24% and 23% at 3 years. High baseline intraocular pressure and primary surgery were associated with higher and lower risks of complete failure, respectively. CONCLUSION:Needle revision is an effective and safe procedure to rescue failing trabeculectomy postponing or avoiding further glaucoma surgery. Eyes with low target intraocular pressure may have poor long-term outcomes.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Rabiolo A,Marchese A,Bettin P,Monteduro D,Galasso M,Dolci MP,Di Matteo F,Fiori M,Ciampi C,Bandello Fdoi
10.1177/1120672119830861subject
Has Abstractpub_date
2020-03-01 00:00:00pages
350-359issue
2eissn
1120-6721issn
1724-6016journal_volume
30pub_type
杂志文章abstract:PURPOSE:To study the morphologic characteristics of the optic nerve (ON) by using an experimental model of knockout mice for the expression of the P27(Kip1) gene, mainly involved in cell cycle arrest, apoptosis control, and retinoblastoma protein phosphorylation. METHODS:Eyeballs with the retrobulbar ON attached were ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700317
更新日期:2007-05-01 00:00:00
abstract:PURPOSE:Malignant melanoma associated with a blue nevus is a rare diagnosis. Additionally, only a handful of cases of malignant melanoma associated with blue nevi involving the ocular structures have been reported. We report a probable case of malignant melanoma associated with a blue nevus with metastasis to multiple ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.6375
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To describe our clinical experience with the efficacy and safety of micropulse transscleral cyclophotocoagulation as a treatment for glaucoma. METHODS:In this retrospective case series, we reviewed the charts of 95 consecutive patients with various glaucoma subtypes who underwent micropulse transscleral cyclop...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119839303
更新日期:2020-07-01 00:00:00
abstract:PURPOSE:To report a case of optic nerve and dura mater involvement as the first sign of multiple myeloma. METHODS:Case report. RESULTS:A 43-year-old woman presented with a headache and decreased vision in both eyes. Ophthalmic examination revealed anterior uveitis and subretinal mass around the optic nerves with acco...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000489
更新日期:2015-01-01 00:00:00
abstract:PURPOSE:To compare topographic indices of surface regularity in dry eye patients and in normal subjects (controls) and to investigate the short-term effect of lacrimal punctal plugs on these indices in dry eye patients. METHODS:The surface regularity index (SRI) and surface asymmetry index (SAI) of the TMS-2 corneal t...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100202
更新日期:2001-04-01 00:00:00
abstract:PURPOSE:Retinopathy is the major cause of ocular morbidity in patients with diabetes mellitus. Chronic hyperglycemia spares no organ and can affect the morphology and function of the various corneal layers, compromising its transparency. This study was conducted to associate the status of corneal endothelium to diabete...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210901900307
更新日期:2009-05-01 00:00:00
abstract::Two cases of idiopathic sclerochoroidal calcification are reported with follow-up of two and ten years. In addition we have reviewed 102 cases of choroidal osteoma, including six misleading case reports which actually described idiopathic sclerochoroidal calcification and not choroidal osteoma. Clinical manifestation ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract:PURPOSE:To identify PAX6 mutations in patients from four Japanese families with aniridia. METHODS:Polymerase chain reaction (PCR)-single stand conformational polymorphism (SSCP) analysis (SSCA) was performed in probands of the families, and restriction analysis using MaeIII or AvaI was carried out in other affected fa...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1177/112067210001000213
更新日期:2000-04-01 00:00:00
abstract:PURPOSE:To report a case series of anterior uveitis after Transepithelial Photorefractive Keratectomy (TransPRK) and determine its incidence, demographics and associated clinical features over a study period of 1 year. METHODS:This retrospective case series comprised of 200 eyes (100 patients) which underwent elective...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120974946
更新日期:2020-11-25 00:00:00
abstract:PURPOSE:Polymethylmethacrylate (PMMA) segments are normally used in additive surgery to treat both corneal ectasia post laser-assisted in situ keratomileusis and keratoconus. The aim of this work was to develop an experimental animal model to induce wound healing in the deep stroma in corneas of hens. METHODS:PMMA seg...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000108
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:To describe the use of silicone oil (SO) in combination with subretinal recombinant tissue plasminogen activator (rtPA) to achieve dislocation of large subretinal hemorrhage secondary to exudative age-related macular degeneration (AMD). METHODS:A single-eye 81-year-old woman, known for exudative AMD, presented...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120952349
更新日期:2020-08-18 00:00:00
abstract:PURPOSE:We report spectral domain optical coherence tomography findings of the peripheral retina in a patient with senile (acquired) retinoschisis. METHODS:This is an observational case report. Spectral domain optical coherence tomography was performed to image the peripheral retina at the area of retinoschisis in a 7...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000610
更新日期:2010-11-01 00:00:00
abstract:PURPOSE:To report on phototherapeutic keratectomy (PTK) in myopic patients who developed spontaneous recurrent corneal erosions (RCE) following IntraLASIK. METHODS:Recurrent corneal erosions developed spontaneously 3-6 months following IntraLASIK in 4 eyes of 4 myopic patients. Diffuse lamellar keratitis (DLK) subsequ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000097
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:To evaluate the effect of IOP lowering on the capillary density of optic nerve head and retinal nerve fiber layer in patients with primary open angle glaucoma. METHODS:Twenty eyes of 14 glaucomatous patients and 15 eyes of nine normal patients were enrolled. The most appropriate hypotonic treatment was applied...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120967233
更新日期:2020-10-29 00:00:00
abstract:PURPOSE:To compare the performance of two different microcatheter systems, iTrack™ 250A and Glaucolight, in ab externo canaloplasty in three major categories: intraocular pressure reduction, drug therapy reintroduction, and evaluation of viscodilation over distension of the inner wall of Schlemm's canal. METHODS:A tot...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119833547
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:The present study compared the expression of brain-derived neurotrophic factor (BDNF) in the lateral geniculate body between form deprivation amblyopia kittens and normal kittens to examine the significance of BDNF in the lateral geniculate body in the pathogenesis of amblyopia. METHODS:Twenty kittens were div...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120953341
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Garcinia cambogia contains hydroxycitric acid. Hydroxycitric acid is a potent competitive inhibitor of adenosine triphosphate citrate lyase which is a key enzyme in the synthesis of fatty acids. Hydroxycitric acid also regulates the level of serotonin. In these regards, hydroxycitric acid has been reported t...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119872364
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:Fabry disease retinal vascular involvement has been widely reported, with narrowing of the retinal arterioles, dilation and irregularity of the retinal veins, and exaggerated tortuosity of the retinal vessels. We evaluated retinal vessel diameter in Fabry disease, by means of a dedicated software, aiming to pro...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119886985
更新日期:2021-01-01 00:00:00
abstract:INTRODUCTION:Parinaud syndrome, caused by midbrain infarction, usually manifests as an ocular conjugate upgaze palsy. However, this sign should not point out straightforwardly to Parinaud syndrome, as other lesions in the central nervous system could cause it. CASE DESCRIPTION:The case of a 47-year-old woman showing a...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119855845
更新日期:2020-11-01 00:00:00
abstract::The risk factors for intraoperative and early postoperative complications were evaluated in 351 consecutive cataract operations at the Oulu University Hospital in 1990. Bleeding into the anterior chamber during the operation was recorded in 8.6%, zonular rupture in 6.6%, posterior capsular rupture in 5.4% and vitreous...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1994-07-01 00:00:00
abstract:AIM:A multicentre, randomized, placebo-controlled double-masked study was conducted to assess the efficacy and safety of Rimexolone 1% eye drops in reducing inflammation after cataract surgery and intra-ocular lens implantation. METHODS:Rimexolone 1% (124 patients) or placebo (58 patients) was given, four times a day ...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:To determine the relationship between movements of the posterior and anterior eye segments during arbitrary gaze shifts and to obtain information for monitoring fixation during radiotherapy for ocular diseases. METHODS:We examined eye movements of ten emmetropic volunteers in a 1.5 T magnetic resonance system....
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210301300212
更新日期:2003-03-01 00:00:00
abstract:PURPOSE:To evaluate persistency (time on initial therapy) and the clinical impact of latanoprost versus beta-blocker monotherapy in treating glaucoma. METHODS:This observational, multicenter, retrospective medical chart review study conducted in four European countries included patients with primary open-angle glaucom...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1177/112067210301304s03
更新日期:2003-07-01 00:00:00
abstract::Indocyanine green video-angiography (ICG) was done twice on three patients with choroidal osteoma. Choroidal osteoma consisted of two portions, a yellow-white area and a surrounding orange area. The early phase of ICG angiography showed hypofluorescence due to blockage, corresponding to the osteoma. However, the hypof...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract:PURPOSE:This study was conducted in 2002-2003 at selected schools of eight health regions of Oman. The authors present risk factors and predictors of progression of myopia between the 7th and 10th grades. METHODS:This was a historical cohort study. A total of 1304 students in 10th grade, both with and without progress...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700115
更新日期:2007-01-01 00:00:00
abstract:PURPOSE:To describe a new technique to split the lens nucleus inside the capsular bag, using a novel pair of instruments. METHODS:Two identical instruments are employed on the horizontal axis to promote nuclear splitting into 2 or more fragments. Each instrument has a portion that functions as a hook (H); an anterior ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000567
更新日期:2015-07-01 00:00:00
abstract:PURPOSE:To describe a case of intraocular lens opacification resembling pseudophakic pseudoexfoliation affecting an AkreosFit intraocular lens (IOL). METHODS:Single case analysis. RESULTS:A patient had IOL opacification resembling pseudophakic pseudoexfoliation. CONCLUSIONS:An 83-year-old woman with normal tension g...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2009-11-01 00:00:00
abstract:PURPOSE:To describe the unusual complication of retinal pigment epithelial (RPE) tear after intravitreal ranibizumab (Lucentis) for subfoveal fibrovascular pigment epithelial detachment (PED) and its effective management. METHODS:Chart review for case report of RPE tear after ranibizumab. RESULTS:An inferior RPE tear...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700432
更新日期:2007-07-01 00:00:00
abstract::Although it is now possible to significantly reduce the incidence of blindness secondary to diabetes mellitus, large numbers of diabetic patients still experience visual loss due to retinal complications of the disease. This implies that protocols for the diagnosis and treatment of diabetic retinopathy used in the var...
journal_title:European journal of ophthalmology
pub_type: 社论
doi:10.1177/112067219900900302
更新日期:1999-07-01 00:00:00
abstract:PURPOSE:The authors wondered whether the spectrum of endophthalmitis and the type of therapy had changed. METHODS:Files of patients who were operated upon for endophthalmitis between 1988 and 2000 were retrospectively analyzed. They were divided into Group 1 (operated upon 1988 to 1994) and Group 2 (1995 to 2000). RE...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210601600217
更新日期:2006-03-01 00:00:00