Abstract:
BACKGROUND:Garcinia cambogia contains hydroxycitric acid. Hydroxycitric acid is a potent competitive inhibitor of adenosine triphosphate citrate lyase which is a key enzyme in the synthesis of fatty acids. Hydroxycitric acid also regulates the level of serotonin. In these regards, hydroxycitric acid has been reported to exhibit weight loss activity. Adverse reactions of G. cambogia from numerous clinical studies demonstrated relatively mild reactions. However, there are some complications of G. cambogia reported in the past: acute liver injury, acute hepatitis, and hepatic failure. However, ocular complications of G. cambogia have not been reported yet. CASE PRESENTATION:A 35-year-old female visited our clinic with decreased vision in the left eye and ocular pain in both eyes for the last 6 days. She also complained of headache, dizziness, and nausea. She had taken G. cambogia extract more than the recommended dose. There was myopic shift with anterior chamber shallowing in both eyes, especially in the left eye. Moreover, swelling and retinal folds of peripapillary retinal nerve fiber layer and macula were observed in both eyes. These ocular complications of G. cambogia extract resolved after discontinuation of the extract and topical and oral steroid treatment. Herein, we report the first case of ocular complications of G. cambogia extract diet pill assessed with optical coherence tomography of optic disk and macula along with dual Scheimpflug analyzer. CONCLUSION:It is necessary that physicians dealing with obesity advice patients about possible visual disturbance of this extract when taken in overdose so that they can see an ophthalmologist immediately.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Cho HK,Han YS,Park JMdoi
10.1177/1120672119872364subject
Has Abstractpub_date
2020-11-01 00:00:00pages
NP21-NP26issue
6eissn
1120-6721issn
1724-6016journal_volume
30pub_type
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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doi:
更新日期:1997-01-01 00:00:00
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更新日期:2015-11-01 00:00:00
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更新日期:2019-03-01 00:00:00
abstract:PURPOSE:To evaluate the changes of corneal biomechanics and the intraocular pressure during pregnancy in a Chinese healthy female population. METHODS:A total of 222 unrelated Chinese females were recruited: 52 non-pregnant, 15 pregnant in the first trimester, 68 pregnant in the second trimester, and 87 pregnant in the...
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journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
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journal_title:European journal of ophthalmology
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更新日期:2019-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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更新日期:2019-06-12 00:00:00
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更新日期:2020-08-27 00:00:00
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journal_title:European journal of ophthalmology
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doi:10.1177/112067210701700530
更新日期:2007-09-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2012-09-01 00:00:00
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更新日期:2006-07-01 00:00:00