Abstract:
PURPOSE:To describe the detailed surgical technique used for harvesting and transplantation of autologous nasal mucosa grafts for ocular surface reconstruction, to evaluate the clinical results and utility of autologous nasal mucosa grafts in ocular surface diseases. METHODS:Autologous nasal mucosa was harvested from either the middle or inferior turbinate. It was transplanted on 11 eyes with severe ocular surface diseases including 4 eyes with chemical burns, 2 eyes with thermal burns, 1 eye with Stevens-Johnson syndrome, 1 eye with erythema multiforme major, and 3 eyes with extensively recurred pterygiums. Clinical outcomes were assessed based on ocular manifestation, epithelization, and visual acuity. RESULTS:The mean follow-up period was 19.9 months (range 13-32 months). Nasal mucosal tissues were safely excised, and their mucosal harvest sites were completely healed in 2 weeks without postoperative complications. All nasal mucosa autograft survived successfully with rapid epithelization, well-developed horizontal vascularization, and abundant mucin secretion. Clinical success, intact ocular surface epithelium without epithelial erosion more than 4 weeks, was achieved in all eyes. There was no recurrence of significant ulceration, conjunctivalization, fibrovascularization, symblepharon, or pterygium. CONCLUSIONS:Goblet cell transplantation using autologous turbinate nasal mucosa presents a promising treatment method in patients with severe ocular surface disorders.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Chun YS,Park IK,Kim JCdoi
10.5301/EJO.2011.6336subject
Has Abstractpub_date
2011-09-01 00:00:00pages
545-51issue
5eissn
1120-6721issn
1724-6016pii
803E2681-8966-4EA6-9B4E-1A505D7C8E70journal_volume
21pub_type
杂志文章abstract:PURPOSE:To describe a new technique to split the lens nucleus inside the capsular bag, using a novel pair of instruments. METHODS:Two identical instruments are employed on the horizontal axis to promote nuclear splitting into 2 or more fragments. Each instrument has a portion that functions as a hook (H); an anterior ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000567
更新日期:2015-07-01 00:00:00
abstract:PURPOSE:To discover the effect of detachment of the posterior vitreous cortex on pattern electroretinogram (PERG) P50 amplitudes in the uninvolved fellow eyes (FE) of patients with macular holes (MH), and to determine the prognostic value of the PERG in identifying the FE of patients with MH that could be at risk for t...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067219900900106
更新日期:1999-01-01 00:00:00
abstract:PURPOSE:To study the impact of ocular hypotensive lipids (OHL) on the incidence, progression, and response to treatment of clinically significant diabetic macular edema (CSDME). METHODS:A total of 379 patients (232 female, 147 male) with a history of diabetes mellitus (DM) and primary open-angle glaucoma (POAG) were i...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000109
更新日期:2012-09-01 00:00:00
abstract:PURPOSE:Evaluate the long term outcomes of myopic-LASIK in a late adolescent population (age ⩾17 and <20 at the time of surgery). METHODS:Monocentric retrospective case series study. Eyes with at least 3 years of follow-up time were included. Primary outcome measures were long term efficacy, safety and stability of th...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120969039
更新日期:2020-10-30 00:00:00
abstract:PURPOSE:To report transient vitreomacular traction (VMT) syndrome following acute blunt trauma associated with incomplete posterior vitreous detachment. METHODS:The authors present the analysis of 2 eyes of consecutive patients with acute VMT following mild blunt trauma. Both patients reported a sudden decrease in vis...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.6425
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To compare diagnostic capabilities and agreement between Oculus-Spark perimetry and 3 procedures of glaucoma morphologic analysis. METHODS:A total of 102 normal eyes and 104 consecutive eyes with suspected or confirmed glaucoma (1 eye per subject) were analyzed in a prospective observational case-control study...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000233
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:To determine the safety and efficacy of photodynamic therapy with verteporfin (V-PDT) in the treatment of exudative idiopathic polypoidal choroidal vasculopathy (IPCV) lesions that were not suitable for laser photocoagulation. METHODS:This was a prospective, open label study in two centers involving 30 consecu...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1177/112067210601600506
更新日期:2006-09-01 00:00:00
abstract:PURPOSE:To investigate the mean values of intraocular pressure (IOP) measured with noncontact tonometer (NCT) and evaluate the factors that may affect IOP. METHODS:A total of 850 subjects who were admitted to our clinic between March 2005 and February 2006 were recruited for the study. Subjects having blepharitis, con...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210901900109
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:To evaluate and compare the glaucoma discrimination ability of macula, macular ganglion cell complex (mGCC), and peripapillary nerve fiber layer (ppNFL) thickness in Chinese patients using Fourier-domain optical coherence tomography (FD-OCT). METHODS:A total of 64 normal subjects (N), 47 glaucoma suspects (GS)...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000131
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:To describe the morphologic alterations in ultrasound biomicroscopy (UBM) present in peripheral vitreoretinal toxocariasis. METHODS:An observational prospective study of case series. Fifteen eyes of 15 patients with clinical and laboratory diagnosis of peripheral vitreoretinal toxocariasis were enrolled. The p...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210401400208
更新日期:2004-03-01 00:00:00
abstract:PURPOSE:To describe the visual phenotype of multiple sclerosis (MS) in the Afro-Caribbean population living in Martinique (French West Indies) and to specify the influence of the migration to metropolitan France on ocular impairment. DESIGN:Prospective consecutive observational case series. METHODS:A complete ophthal...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210501500313
更新日期:2005-05-01 00:00:00
abstract:PURPOSE:Pterygium is an invasive and highly vascularized growth, thought to arise from activated and proliferating limbal epithelial stem cells. Epidemiologic studies have found the increase of active angiogenic and epithelial growth factors in pterygia, and implicated that these molecules could be involved directly or...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800104
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:To assess the long-term results of viscotrabeculotomy in infants with primary congenital glaucoma and to compare its outcome with conventional trabeculotomy. PATIENTS AND METHODS:A prospective randomized comparative study included infants with primary congenital glaucoma younger than 2 years. Patients were div...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120922453
更新日期:2020-05-26 00:00:00
abstract:PURPOSE:To discuss how optical coherence tomography can be used to identify separated lenticular planes during small incision lenticule extraction (SMILE). METHODS:SMILE procedures were performed on 26 eyes of 13 patients. An anterior segment optical coherence tomography examination was performed after laser scan. Ant...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119853207
更新日期:2020-09-01 00:00:00
abstract:AIM:To review published literature concerning cataract surgery and dry eye disease (DED). METHODS:A search was undertaken using the following: PubMed (all years), Web of Science (all years), Ovid MEDLINE(R) (1946 to 12 December 2019), Ovid MEDLINE(R) Daily Update 10 December 2019, MEDLINE and MEDLINE non-indexed items...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1177/1120672120929958
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To describe the use of silicone oil (SO) in combination with subretinal recombinant tissue plasminogen activator (rtPA) to achieve dislocation of large subretinal hemorrhage secondary to exudative age-related macular degeneration (AMD). METHODS:A single-eye 81-year-old woman, known for exudative AMD, presented...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120952349
更新日期:2020-08-18 00:00:00
abstract:PURPOSE:To report one case of multiple and bilateral choroidal tumors from a poorly differentiated small cell neuroendocrine carcinoma of unknown primary. METHODS:The case of a 30-years-old white female who developed multiple and bilateral choroidal tumors from a poorly differentiated small cell neuroendocrine carcino...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.3247
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:Cataract formation represents a serious problem in the elderly, and has a large impact on healthcare budget. The oxidative stress form and intensity might determine the cataract type and pigmentation, making efforts in the cataract prevention challenge more complex. METHODS:This is a retrospective cross-sectio...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800501
更新日期:2008-09-01 00:00:00
abstract:PURPOSE:To survey the routine practice of consultant ophthalmic surgeons in the United Kingdom in preventing postoperative endophthalmitis following cataract surgery. METHODS:This is a cross-sectional questionnaire-based study. A questionnaire was sent to consultant ophthalmic surgeons in university teaching hospital ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1177/112067210601600306
更新日期:2006-05-01 00:00:00
abstract:INTRODUCTION:Parinaud syndrome, caused by midbrain infarction, usually manifests as an ocular conjugate upgaze palsy. However, this sign should not point out straightforwardly to Parinaud syndrome, as other lesions in the central nervous system could cause it. CASE DESCRIPTION:The case of a 47-year-old woman showing a...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119855845
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of intravitreal dexamethasone implant in treatment naïve eyes with diabetic macular edema (DME). METHODS:A retrospective analysis of treatment naïve eyes with DME which received intravitreal dexamethasone implant between January 2016 and March 2018 was done. Demographic deta...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120949761
更新日期:2020-08-10 00:00:00
abstract:PURPOSE:To report on a case of episcleral hemangioma in a child. METHODS:A 3-year-old boy presented with a 4-week history of limbal mass in the left eye and had an excision of that mass. RESULTS:There was an 8 x 7 mm oval lesion, 3-4 mm below the inferior limbus. It was reddish, sharply elevated with smooth surface, ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210901900220
更新日期:2009-03-01 00:00:00
abstract:PURPOSE:Malignant melanoma associated with a blue nevus is a rare diagnosis. Additionally, only a handful of cases of malignant melanoma associated with blue nevi involving the ocular structures have been reported. We report a probable case of malignant melanoma associated with a blue nevus with metastasis to multiple ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.6375
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To conduct an observational, multicenter study to evaluate real-world clinical efficacy and safety of the 0.2 µg/day fluocinolone acetonide (FAc) implant in the treatment of patients with chronic diabetic macular edema (DME) in 3 large hospital ophthalmology departments in the United Kingdom. METHODS:Fluocinol...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.5301/ejo.5000929
更新日期:2017-05-11 00:00:00
abstract:PURPOSE:To compare the IOP readings of an ocular blood flow (OBF) tonograph (OBF Labs UK Ltd) with Goldmann applanation tonometry. METHODS:194 patients were studied. In group 1, the software version 8.2 of the OBF tonograph was used in 214 eyes of 107 patients and in group 2, the 11.2 version of the tonograph was used...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1998-07-01 00:00:00
abstract::Ultrasound tissue characterization parameters of size and acoustic concentration can be used to sub-classify uveal melanoma and estimate the patient's risk of death. Histologically determined microcirculation patterns have also been found to sub-classify uveal melanoma and predict patient's risk of death. This study e...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract:PURPOSE:To evaluate the effect on lacrimal function and ocular complications in patients with severe acne vulgaris during systemic treatment with 13-cis-retinoic acid (isotretinoin). METHODS:Forty patients with acne vulgaris were treated with systemic isotretinoin at dosages of 0.5-1 mg/kg per day for two months. Full...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:2002-05-01 00:00:00
abstract:INTRODUCTION:Scleral buckling (SB) has been the first technique to repair a retinal detachment (RD) and it is still largely in use. Pars plana vitrectomy (PPV) is currently the most common technique, being more versatile and easier to approach. Here we report on a new SB variant, modified by using some of the latest te...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120945091
更新日期:2020-07-22 00:00:00
abstract:PURPOSE:Preservatives in glaucoma medications have been associated with ocular toxicity. We compared ocular signs and symptoms in patients with open-angle glaucoma or ocular hypertension treated in monotherapy with preserved or preservative-free prostaglandin analogues. METHODS:Observational cross-sectional clinical s...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672118805877
更新日期:2019-11-01 00:00:00
abstract:PURPOSE:Mutations in the ABCA4 gene result in a broad spectrum of severe retinal degeneration, including Stargardt macular dystrophy, fundus flavimaculatus, autosomal recessive retinitis pigmentosa, and cone-rod dystrophy. In addition to the detection of well-characterized mutations, genetic testing frequently yields n...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5001019
更新日期:2018-01-01 00:00:00