Technique for autologous nasal mucosa transplantation in severe ocular surface disease.

Abstract:

PURPOSE:To describe the detailed surgical technique used for harvesting and transplantation of autologous nasal mucosa grafts for ocular surface reconstruction, to evaluate the clinical results and utility of autologous nasal mucosa grafts in ocular surface diseases. METHODS:Autologous nasal mucosa was harvested from either the middle or inferior turbinate. It was transplanted on 11 eyes with severe ocular surface diseases including 4 eyes with chemical burns, 2 eyes with thermal burns, 1 eye with Stevens-Johnson syndrome, 1 eye with erythema multiforme major, and 3 eyes with extensively recurred pterygiums. Clinical outcomes were assessed based on ocular manifestation, epithelization, and visual acuity. RESULTS:The mean follow-up period was 19.9 months (range 13-32 months). Nasal mucosal tissues were safely excised, and their mucosal harvest sites were completely healed in 2 weeks without postoperative complications. All nasal mucosa autograft survived successfully with rapid epithelization, well-developed horizontal vascularization, and abundant mucin secretion. Clinical success, intact ocular surface epithelium without epithelial erosion more than 4 weeks, was achieved in all eyes. There was no recurrence of significant ulceration, conjunctivalization, fibrovascularization, symblepharon, or pterygium. CONCLUSIONS:Goblet cell transplantation using autologous turbinate nasal mucosa presents a promising treatment method in patients with severe ocular surface disorders.

journal_name

Eur J Ophthalmol

authors

Chun YS,Park IK,Kim JC

doi

10.5301/EJO.2011.6336

subject

Has Abstract

pub_date

2011-09-01 00:00:00

pages

545-51

issue

5

eissn

1120-6721

issn

1724-6016

pii

803E2681-8966-4EA6-9B4E-1A505D7C8E70

journal_volume

21

pub_type

杂志文章
  • Symmetric bimanual phacofragmentation: a new approach for nucleus disassembly.

    abstract:PURPOSE:To describe a new technique to split the lens nucleus inside the capsular bag, using a novel pair of instruments. METHODS:Two identical instruments are employed on the horizontal axis to promote nuclear splitting into 2 or more fragments. Each instrument has a portion that functions as a hook (H); an anterior ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000567

    authors: Jacobovitz S,Roitberg M,Massote V,Martins B,Vasconcelos-Santos DV

    更新日期:2015-07-01 00:00:00

  • Pattern reversal electroretinograms in patients with unilateral idiopathic full thickness macular holes.

    abstract:PURPOSE:To discover the effect of detachment of the posterior vitreous cortex on pattern electroretinogram (PERG) P50 amplitudes in the uninvolved fellow eyes (FE) of patients with macular holes (MH), and to determine the prognostic value of the PERG in identifying the FE of patients with MH that could be at risk for t...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067219900900106

    authors: Gündüz K

    更新日期:1999-01-01 00:00:00

  • Impact of ocular hypotensive lipids on clinically significant diabetic macular edema.

    abstract:PURPOSE:To study the impact of ocular hypotensive lipids (OHL) on the incidence, progression, and response to treatment of clinically significant diabetic macular edema (CSDME). METHODS:A total of 379 patients (232 female, 147 male) with a history of diabetes mellitus (DM) and primary open-angle glaucoma (POAG) were i...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000109

    authors: Patel AS,Patel CC,Goyal A,Anchala A,Adrean S,Hughes B,Mahmoud TH

    更新日期:2012-09-01 00:00:00

  • Laser-assisted in situ keratomileusis long term outcomes in late adolescence.

    abstract:PURPOSE:Evaluate the long term outcomes of myopic-LASIK in a late adolescent population (age ⩾17 and <20 at the time of surgery). METHODS:Monocentric retrospective case series study. Eyes with at least 3 years of follow-up time were included. Primary outcome measures were long term efficacy, safety and stability of th...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120969039

    authors: Alió Del Barrio JL,Canto-Cerdán M,Bo M,Subirana N,Alió JL

    更新日期:2020-10-30 00:00:00

  • Transient vitreomacular traction syndrome caused by traumatic incomplete posterior vitreous detachment.

    abstract:PURPOSE:To report transient vitreomacular traction (VMT) syndrome following acute blunt trauma associated with incomplete posterior vitreous detachment. METHODS:The authors present the analysis of 2 eyes of consecutive patients with acute VMT following mild blunt trauma. Both patients reported a sudden decrease in vis...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/EJO.2011.6425

    authors: Lorusso M,Micelli Ferrari L,Leozappa M,Modoni AP,Micelli Ferrari T

    更新日期:2011-09-01 00:00:00

  • Oculus-Spark perimetry compared with 3 procedures of glaucoma morphologic analysis (GDx, HRT, and OCT).

    abstract:PURPOSE:To compare diagnostic capabilities and agreement between Oculus-Spark perimetry and 3 procedures of glaucoma morphologic analysis. METHODS:A total of 102 normal eyes and 104 consecutive eyes with suspected or confirmed glaucoma (1 eye per subject) were analyzed in a prospective observational case-control study...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000233

    authors: Gonzalez de la Rosa M,Gonzalez-Hernandez M,Sanchez-Garcia M,Rodriguez de la Vega R,Diaz-Aleman T,Pareja Rios A

    更新日期:2013-05-01 00:00:00

  • Photodynamic therapy with verteporfin in the treatment of exudative idiopathic polypoidal choroidal vasculopathy.

    abstract:PURPOSE:To determine the safety and efficacy of photodynamic therapy with verteporfin (V-PDT) in the treatment of exudative idiopathic polypoidal choroidal vasculopathy (IPCV) lesions that were not suitable for laser photocoagulation. METHODS:This was a prospective, open label study in two centers involving 30 consecu...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1177/112067210601600506

    authors: Mauget-Faÿsse M,Quaranta-El Maftouhi M,De La Marnièrre E,Leys A

    更新日期:2006-09-01 00:00:00

  • Factors affecting intraocular pressure measured by noncontact tonometer.

    abstract:PURPOSE:To investigate the mean values of intraocular pressure (IOP) measured with noncontact tonometer (NCT) and evaluate the factors that may affect IOP. METHODS:A total of 850 subjects who were admitted to our clinic between March 2005 and February 2006 were recruited for the study. Subjects having blepharitis, con...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210901900109

    authors: Yazici A,Sen E,Ozdal P,Aksakal FN,Altinok A,Oncul H,Koklu G

    更新日期:2009-01-01 00:00:00

  • Fourier domain OCT measurement of macular, macular ganglion cell complex, and peripapillary RNFL thickness in glaucomatous Chinese eyes.

    abstract:PURPOSE:To evaluate and compare the glaucoma discrimination ability of macula, macular ganglion cell complex (mGCC), and peripapillary nerve fiber layer (ppNFL) thickness in Chinese patients using Fourier-domain optical coherence tomography (FD-OCT). METHODS:A total of 64 normal subjects (N), 47 glaucoma suspects (GS)...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000131

    authors: Chen J,Huang H,Wang M,Sun X,Qian S

    更新日期:2012-11-01 00:00:00

  • Ultrasound biomicroscopy findings in peripheral vitreoretinal toxocariasis.

    abstract:PURPOSE:To describe the morphologic alterations in ultrasound biomicroscopy (UBM) present in peripheral vitreoretinal toxocariasis. METHODS:An observational prospective study of case series. Fifteen eyes of 15 patients with clinical and laboratory diagnosis of peripheral vitreoretinal toxocariasis were enrolled. The p...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210401400208

    authors: Cella W,Ferreira E,Torigoe AM,Macchiaverni-Filho N,Balarin V

    更新日期:2004-03-01 00:00:00

  • Visual phenotype of multiple sclerosis in the Afro-Caribbean population and the influence of migration to metropolitan France.

    abstract:PURPOSE:To describe the visual phenotype of multiple sclerosis (MS) in the Afro-Caribbean population living in Martinique (French West Indies) and to specify the influence of the migration to metropolitan France on ocular impairment. DESIGN:Prospective consecutive observational case series. METHODS:A complete ophthal...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210501500313

    authors: Merle H,Smadja D,Merle S,Olindo S,Signate A,Donnio A,Richer R,Bonnan M,Cabre P

    更新日期:2005-05-01 00:00:00

  • Evaluation of transforming growth factor and vascular endothelial growth factor polymorphisms in Taiwan Chinese patients with pterygium.

    abstract:PURPOSE:Pterygium is an invasive and highly vascularized growth, thought to arise from activated and proliferating limbal epithelial stem cells. Epidemiologic studies have found the increase of active angiogenic and epithelial growth factors in pterygia, and implicated that these molecules could be involved directly or...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210801800104

    authors: Bau DT,Chiang CC,Tsai YY,Lee CC,Tsai Y,Lin CC,Tsai CH,Tsai FJ

    更新日期:2008-01-01 00:00:00

  • Five-year results of viscotrabeculotomy versus conventional trabeculotomy in primary congenital glaucoma: A randomized controlled study.

    abstract:PURPOSE:To assess the long-term results of viscotrabeculotomy in infants with primary congenital glaucoma and to compare its outcome with conventional trabeculotomy. PATIENTS AND METHODS:A prospective randomized comparative study included infants with primary congenital glaucoma younger than 2 years. Patients were div...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120922453

    authors: Elwehidy AS,Hagras SM,Bayoumi N,AbdelGhafar AE,Badawi AE

    更新日期:2020-05-26 00:00:00

  • Identification of separated lenticular planes using optical coherence tomography.

    abstract:PURPOSE:To discuss how optical coherence tomography can be used to identify separated lenticular planes during small incision lenticule extraction (SMILE). METHODS:SMILE procedures were performed on 26 eyes of 13 patients. An anterior segment optical coherence tomography examination was performed after laser scan. Ant...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672119853207

    authors: Zheng K,Han T,Zhao F,Han Y,Zhou X

    更新日期:2020-09-01 00:00:00

  • Cataract surgery and dry eye disease: A review.

    abstract:AIM:To review published literature concerning cataract surgery and dry eye disease (DED). METHODS:A search was undertaken using the following: PubMed (all years), Web of Science (all years), Ovid MEDLINE(R) (1946 to 12 December 2019), Ovid MEDLINE(R) Daily Update 10 December 2019, MEDLINE and MEDLINE non-indexed items...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1177/1120672120929958

    authors: Naderi K,Gormley J,O'Brart D

    更新日期:2020-09-01 00:00:00

  • Silicone oil-induced displacement of subretinal hemorrhage in age-related macular degeneration.

    abstract:PURPOSE:To describe the use of silicone oil (SO) in combination with subretinal recombinant tissue plasminogen activator (rtPA) to achieve dislocation of large subretinal hemorrhage secondary to exudative age-related macular degeneration (AMD). METHODS:A single-eye 81-year-old woman, known for exudative AMD, presented...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120952349

    authors: Corbelli E,Iuliano L,Fogliato G,Bandello F,Codenotti M

    更新日期:2020-08-18 00:00:00

  • Multiple bilateral choroidal metastatic tumors from a small-cell neuroendocrine carcinoma.

    abstract:PURPOSE:To report one case of multiple and bilateral choroidal tumors from a poorly differentiated small cell neuroendocrine carcinoma of unknown primary. METHODS:The case of a 30-years-old white female who developed multiple and bilateral choroidal tumors from a poorly differentiated small cell neuroendocrine carcino...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/EJO.2008.3247

    authors: Nicolo' M,Piccolino FC,Ghiglione D,Nicol G,Calabria G

    更新日期:2005-01-01 00:00:00

  • Oxidative stress intensity in lens and aqueous depending on age-related cataract type and brunescense.

    abstract:PURPOSE:Cataract formation represents a serious problem in the elderly, and has a large impact on healthcare budget. The oxidative stress form and intensity might determine the cataract type and pigmentation, making efforts in the cataract prevention challenge more complex. METHODS:This is a retrospective cross-sectio...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210801800501

    authors: Zoric L,Elek-Vlajic S,Jovanovic M,Kisic B,Djokic O,Canadanovic V,Cosic V,Jaksic V

    更新日期:2008-09-01 00:00:00

  • Prophylaxis against infection in cataract surgery: a survey of routine practice.

    abstract:PURPOSE:To survey the routine practice of consultant ophthalmic surgeons in the United Kingdom in preventing postoperative endophthalmitis following cataract surgery. METHODS:This is a cross-sectional questionnaire-based study. A questionnaire was sent to consultant ophthalmic surgeons in university teaching hospital ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.1177/112067210601600306

    authors: Ang GS,Barras CW

    更新日期:2006-05-01 00:00:00

  • Acute upward gaze palsy: Not always Parinaud syndrome.

    abstract:INTRODUCTION:Parinaud syndrome, caused by midbrain infarction, usually manifests as an ocular conjugate upgaze palsy. However, this sign should not point out straightforwardly to Parinaud syndrome, as other lesions in the central nervous system could cause it. CASE DESCRIPTION:The case of a 47-year-old woman showing a...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672119855845

    authors: Rossi S,Frisullo G,Iorio R

    更新日期:2020-11-01 00:00:00

  • Efficacy and safety of intravitreal dexamethasone implant in treatment naïve eyes with diabetic macular edema: Real world experience.

    abstract:PURPOSE:To evaluate the efficacy and safety of intravitreal dexamethasone implant in treatment naïve eyes with diabetic macular edema (DME). METHODS:A retrospective analysis of treatment naïve eyes with DME which received intravitreal dexamethasone implant between January 2016 and March 2018 was done. Demographic deta...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120949761

    authors: Ratra D,Sharma U,Dalan D

    更新日期:2020-08-10 00:00:00

  • Episcleral hemangioma as an isolated finding.

    abstract:PURPOSE:To report on a case of episcleral hemangioma in a child. METHODS:A 3-year-old boy presented with a 4-week history of limbal mass in the left eye and had an excision of that mass. RESULTS:There was an 8 x 7 mm oval lesion, 3-4 mm below the inferior limbus. It was reddish, sharply elevated with smooth surface, ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210901900220

    authors: Al-Ghadeer H,Al-Rajhi A,Riley F

    更新日期:2009-03-01 00:00:00

  • Multiple bilateral ocular metastases from malignant melanoma associated with blue nevi.

    abstract:PURPOSE:Malignant melanoma associated with a blue nevus is a rare diagnosis. Additionally, only a handful of cases of malignant melanoma associated with blue nevi involving the ocular structures have been reported. We report a probable case of malignant melanoma associated with a blue nevus with metastasis to multiple ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/EJO.2011.6375

    authors: Kelmenson AT,Grover S

    更新日期:2011-09-01 00:00:00

  • Diabetic macular edema outcomes in eyes treated with fluocinolone acetonide 0.2 µg/d intravitreal implant: real-world UK experience.

    abstract:PURPOSE:To conduct an observational, multicenter study to evaluate real-world clinical efficacy and safety of the 0.2 µg/day fluocinolone acetonide (FAc) implant in the treatment of patients with chronic diabetic macular edema (DME) in 3 large hospital ophthalmology departments in the United Kingdom. METHODS:Fluocinol...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,多中心研究

    doi:10.5301/ejo.5000929

    authors: El-Ghrably I,Steel DHW,Habib M,Vaideanu-Collins D,Manvikar S,Hillier RJ

    更新日期:2017-05-11 00:00:00

  • Clinical comparison of the ocular blood flow tonograph and the Goldmann applanation tonometer.

    abstract:PURPOSE:To compare the IOP readings of an ocular blood flow (OBF) tonograph (OBF Labs UK Ltd) with Goldmann applanation tonometry. METHODS:194 patients were studied. In group 1, the software version 8.2 of the OBF tonograph was used in 214 eyes of 107 patients and in group 2, the 11.2 version of the tonograph was used...

    journal_title:European journal of ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Esgin H,Alimgil ML,Erda S

    更新日期:1998-07-01 00:00:00

  • Correlation of microcirculation architecture with ultrasound backscatter parameters of uveal melanoma.

    abstract::Ultrasound tissue characterization parameters of size and acoustic concentration can be used to sub-classify uveal melanoma and estimate the patient's risk of death. Histologically determined microcirculation patterns have also been found to sub-classify uveal melanoma and predict patient's risk of death. This study e...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Coleman DJ,Rondeau MJ,Silverman RH,Folberg R,Rummelt V,Woods SM,Lizzi FL

    更新日期:1995-04-01 00:00:00

  • Lacrimal function and ocular complications in patients treated with systemic isotretinoin.

    abstract:PURPOSE:To evaluate the effect on lacrimal function and ocular complications in patients with severe acne vulgaris during systemic treatment with 13-cis-retinoic acid (isotretinoin). METHODS:Forty patients with acne vulgaris were treated with systemic isotretinoin at dosages of 0.5-1 mg/kg per day for two months. Full...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Bozkurt B,Irkeç MT,Atakan N,Orhan M,Geyik PO

    更新日期:2002-05-01 00:00:00

  • Wide-angle 3D viewing system with valved trocar applied to chandelier-assisted scleral buckling.

    abstract:INTRODUCTION:Scleral buckling (SB) has been the first technique to repair a retinal detachment (RD) and it is still largely in use. Pars plana vitrectomy (PPV) is currently the most common technique, being more versatile and easier to approach. Here we report on a new SB variant, modified by using some of the latest te...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120945091

    authors: La Spina C,Del Turco C,Bogetto C,Panico E,Giobbio DC,Panico C

    更新日期:2020-07-22 00:00:00

  • Objective ocular surface tolerance in patients with glaucoma treated with topical preserved or unpreserved prostaglandin analogues.

    abstract:PURPOSE:Preservatives in glaucoma medications have been associated with ocular toxicity. We compared ocular signs and symptoms in patients with open-angle glaucoma or ocular hypertension treated in monotherapy with preserved or preservative-free prostaglandin analogues. METHODS:Observational cross-sectional clinical s...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672118805877

    authors: El Ameen A,Vandermeer G,Khanna RK,Pisella PJ

    更新日期:2019-11-01 00:00:00

  • Novel ABCA4 mutation leads to loss of a conserved C-terminal motif: implications for predicting pathogenicity based on genetic testing.

    abstract:PURPOSE:Mutations in the ABCA4 gene result in a broad spectrum of severe retinal degeneration, including Stargardt macular dystrophy, fundus flavimaculatus, autosomal recessive retinitis pigmentosa, and cone-rod dystrophy. In addition to the detection of well-characterized mutations, genetic testing frequently yields n...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5001019

    authors: Wangtiraumnuay N,Capasso J,Tsukikawa M,Levin A,Biswas-Fiss E

    更新日期:2018-01-01 00:00:00