Abstract:
PURPOSE:To investigate whether topical nonsteroidal antiinflammatory drugs (NSAIDs) are useful, in the absence of concomitant corticosteroid therapy, in limiting postoperative inflammation after uncomplicated cataract surgery. METHODS:A total of 328 patients were enrolled in a prospective, randomized, double-masked, parallel-group, active-controlled study. Anterior chamber inflammation (ACI) was evaluated as the primary efficacy parameter. Only patients with moderate inflammation (ACI score of < or =4) the day after surgery were randomized and treated with NSAIDs. A novel topical formulation containing 0.2% sodium naproxen was compared with 0.1% diclofenac. Both were administered three times a day for 14 consecutive days. Ocular inflammation was measured after 7 and 14 days by using slit-lamp biomicroscopy. Safety parameters were also evaluated at the same time. RESULTS:Both treatments were equally effective in controlling postsurgical inflammation. No statistically significant differences between treatment groups were observed for the safety variables. No serious adverse events (AEs) occurred during the course of the study. The most frequent AE reported with naproxen was eye redness. CONCLUSIONS:NSAIDs can effectively be used without concurrent administration of corticosteroids to control postoperative inflammation after uncomplicated cataract surgery. In addition, naproxen ophthalmic solution may be considered a suitable alternative to the currently available NSAIDs.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Russo P,Papa V,Russo S,Di Bella A,Pabst G,Milazzo G,Balestrazzi A,Caporossi A,Naproxen Study Group.subject
Has Abstractpub_date
2005-09-01 00:00:00pages
598-606issue
5eissn
1120-6721issn
1724-6016journal_volume
15pub_type
临床试验,杂志文章,随机对照试验abstract:PURPOSE:The effect of elevated blood glucose level on the myogenic response of human retinal arterioles to acute increases in blood pressure is investigated. METHODS:The vascular response to raised blood pressure (Bayliss effect) was measured in 12 healthy volunteers by use of the retinal vessel analyzer (RVA). For a ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210501500109
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To report on the presence of 4 different structures visualized by confocal microscopy in patients whose clinical presentation suggested infection by Acanthamoeba. METHODS:Data and charts of 28 consecutive patients were analyzed in a retrospective study. Four types of structures were recognized by confocal micr...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000817
更新日期:2017-01-19 00:00:00
abstract:PURPOSE:To describe and compare long-term (> or = 36 months) effects of patients with 86 primary pterygia treated with bare sclera extirpation (BSE) followed by Beta-RT or by sham irradiation. METHODS:Prospective, multicenter, randomized, double-blind study. After BSE of their pterygium, patients were randomized to ei...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/112067210801800301
更新日期:2008-05-01 00:00:00
abstract:PURPOSE:To evaluate accuracy and inter-rater reliability of RetCam fundus images and digital camera fluorangioscopic images in acute retinopathy of prematurity (ROP) by comparing diagnoses given by trainee ophthalmologists with those provided by expert ophthalmologists. METHODS:This is a multicenter retrospective ob...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.5301/ejo.5000319
更新日期:2013-11-01 00:00:00
abstract:PURPOSE:To investigate the low mesopic contrast sensitivity function (LMCSF) of patients implanted with different modern optical bifocal and trifocal designs of multifocal intraocular lenses (mfIOLs). METHODS:This prospective, comparative, nonrandomized consecutive case series included 180 eyes that underwent cataract...
journal_title:European journal of ophthalmology
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doi:10.5301/ejo.5000777
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abstract:PURPOSE:To assess the long-term results of viscotrabeculotomy in infants with primary congenital glaucoma and to compare its outcome with conventional trabeculotomy. PATIENTS AND METHODS:A prospective randomized comparative study included infants with primary congenital glaucoma younger than 2 years. Patients were div...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120922453
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abstract:PURPOSE:To evaluate the effect of posterior sub-tenon triamcinolone acetonide (TA) injection on clinical, angiographic, and optical coherence tomographic (OCT) parameters in refractory diabetic macular edema (DME). METHODS:In a double-masked placebo-controlled clinical trial, 64 eyes were randomly assigned to two grou...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1177/112067210501500614
更新日期:2005-11-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of laser in situ keratomileusis (LASIK) in partially refractive accommodative esotropia (pRAE) and fully refractive accommodative esotropia (fRAE). METHODS:Forty-two eyes of 21 patients who had LASIK for correcting hyperopic refractive error were evaluated. Refractive errors...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210901900508
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:Twenty-two people with a history of grass pollen allergic conjunctivitis were enrolled outside the pollen season in this study to compare the efficacy of 0.05% mequitazine eyedrops with topical 2% disodium cromoglycate. METHODS:This randomized, double-blind study compared right and left eyes. Subjects received...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/112067210001000103
更新日期:2000-01-01 00:00:00
abstract:PURPOSE:To document incidence of and risk factors for development of retinopathy of prematurity (ROP) in a population of low birthweight infants (< 1500 g). METHODS:The authors registered clinical characteristics (birthweight, gestational age (GA), Clinical Risk Index for Babies (CRIB), Apgar score, respiratory charac...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672103013009-1009
更新日期:2003-11-01 00:00:00
abstract:PURPOSE:To evaluate the use of the resorbable polylactic acid polymer implants (Resorb X) in the management of orbital floor blow-out fractures as regards safety, cosmetic, and functional results. METHODS:In a prospective, interventional case series, 22 patients with traumatic blow-out floor fractures underwent lower ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120928005
更新日期:2020-05-31 00:00:00
abstract:PURPOSE:To review and analyze the epidemiological profile, clinical characteristics and visual outcomes in patients attended for traumatic open globe injury (OGI) at our hospital over a 5-year period. DESIGN:Retrospective chart review study. METHODS:Retrospective analysis of all patients attended at Fundación Jiménez...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2020-10-10 00:00:00
abstract:PURPOSE:To evaluate the efficacy of switching from bevacizumab to ranibizumab in patients with diabetic macular edema (DME). METHODS:This was a retrospective study of patients with DME initially treated with bevacizumab and switched to ranibizumab. Visual acuity (VA) and central retinal thickness (CRT) were retrieved ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2017-03-10 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2020-12-08 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.1534
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To report the visual and refractive outcomes of sequential intracorneal ring segment (ICRS) and toric phakic intraocular lens (IOL) insertion for visual rehabilitation in keratoconus. METHODS:A retrospective interventional cohort study was performed through the Corneoplastics unit and Eye Bank, Queen Victoria ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120969600
更新日期:2020-11-02 00:00:00
abstract::Strabismus fixus is a rare condition and usually is of convergent type in which one or both eyes are anchored in a position of extreme adduction. Convergent type strabismus fixus is considered to be a congenital disorder and a part of congenital extraocular muscle fibrosis syndrome. Villasecca and Martinez described a...
journal_title:European journal of ophthalmology
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doi:10.1177/112067210301300214
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abstract:PURPOSE:This study was performed to test the diagnostic capability of the minimum rim width compared to peripapillary retinal nerve fiber layer thickness in patients with glaucoma. METHODS:A case control, observer masked study, was conducted. Minimum rim width and retinal nerve fiber layer thickness were assessed usin...
journal_title:European journal of ophthalmology
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abstract:PURPOSE:To report a case of Escherichia coli endophthalmitis after trans-scleral resection of an uveal melanoma. METHODS:A large ciliary body melanoma was treated by trans-scleral resection and full-thickness sclerectomy because of epibulbar tumor extrusion, followed by adjuvant ruthenium plaque therapy. RESULTS:Two ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2002-09-01 00:00:00
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journal_title:European journal of ophthalmology
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journal_title:European journal of ophthalmology
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abstract:PURPOSE:To evaluate visual outcomes, eye movement abnormalities, and postoperative complications after secondary posterior chamber intraocular lens (IOL) implantation in aphakic children who had initial LAC correction. METHODS:A retrospective study was carried out on 53 patients (94 eyes). Following aphakic surgery an...
journal_title:European journal of ophthalmology
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更新日期:2008-11-01 00:00:00
abstract::In myopia patients, Rh and acid phosphatase were typed in two groups: group 1 consisted of 214 patients with low myopia (-6 D or less); group 2 of 124 patients with high myopia (more than -6 D). Statistical analysis of the markers showed a good Hardy-Weinberg equilibrium for both groups. In the Rh system there was a s...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract:PURPOSE:To report a case of a combined branch retinal artery and vein occlusion in a patient with hepatitis C treated with interferon and ribavirin. METHODS:A 29-year-old man with a 1-week history of sudden visual field defect and decrease of central visual acuity was examined. RESULTS:Ophthalmoscopy and fluorescein ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.4623
更新日期:2005-01-01 00:00:00
abstract::Vascular involvement is a well known manifestation of Behçet's disease (BD) and may effect systemic and regional circulation in patients with BD. We evaluated ophthalmic and central retinal artery flow velocities in these patients. Mean ophthalmic and central retinal artery flow velocities were lower in patients with ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract:PURPOSE:To determine the outcome, including the intraoperative and postoperative complications, of phacoemulsification with intraocular lens (IOL) implantation in myopic eyes with axial length of 26 mm or more that had undergone previous pars plana vitrectomy (PPV). METHODS:This prospective study comprised 37 highly m...
journal_title:European journal of ophthalmology
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更新日期:2011-07-01 00:00:00
abstract:PURPOSE:Cataract formation represents a serious problem in the elderly, and has a large impact on healthcare budget. The oxidative stress form and intensity might determine the cataract type and pigmentation, making efforts in the cataract prevention challenge more complex. METHODS:This is a retrospective cross-sectio...
journal_title:European journal of ophthalmology
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更新日期:2008-09-01 00:00:00
abstract:PURPOSE:To investigate the early neurodegenerative changes of inner retina and choroid in type 1 and type 2 diabetic patients without retinopathy and with early-stage retinopathy. METHODS:In this observational cross-sectional study, 90 right eyes of 90 naive type 1 and 2 diabetic patients without diabetic retinopathy ...
journal_title:European journal of ophthalmology
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abstract:PURPOSE:The convergence excess esotropia (CEET) is defined when near esotropia is greater than the distance by at least 10 PD while the eye is corrected with the full cycloplegic refraction. The purpose of this study is to evaluate the effect of a modified technique of Y- split recession of the medial rectus muscles on...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2020-10-23 00:00:00
abstract:PURPOSE:Timely screening of premature babies is an important initial step in the management of retinopathy of prematurity (ROP) as earlier treatment results in improved visual prognosis. Screening criteria for ROP currently recommended by the American Academy of Pediatrics may not be applicable in developing countries....
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000417
更新日期:2010-07-01 00:00:00