Abstract：
PURPOSE:To evaluate the efficacy of switching from bevacizumab to ranibizumab in patients with diabetic macular edema (DME). METHODS:This was a retrospective study of patients with DME initially treated with bevacizumab and switched to ranibizumab. Visual acuity (VA) and central retinal thickness (CRT) were retrieved at fixed timepoints prior to and after the switch. RESULTS:Forty eyes of 32 patients were included in the study. The difference in VA between any of these fixed timepoints was not statistically significant. A significant gain in VA was found in eyes that lost more than 0.1 logMAR during treatment with the last 3 bevacizumab injections. The mean CRT was significantly lower after the first 3 ranibizumab injections and at the final follow-up (p<0.001), a 67 ± 14 μm and 78 ± 18 μm reduction in thickness, respectively. CONCLUSIONS:Switching to ranibizumab resulted in a significant decrease in the CRT of eyes with DME, and should be considered when there is a lack of response or deterioration while on bevacizumab injections. A significant gain in VA was observed in a subgroup of eyes that lost more than one line while receiving the last 3 bevacizumab injections prior to the switch.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Katz G,Moisseiev E,Goldenberg D,Moisseiev J,Lomnicky Y,Abend Y,Treister G,Levkovitch-Verbin Hdoi
10.5301/ejo.5000838subject
Has Abstractpub_date
2017-03-10 00:00:00pages
210-214issue
2eissn
1120-6721issn
1724-6016pii
84D01779-6B50-48AA-93F4-5DBBE1D5D227journal_volume
27pub_type
杂志文章abstract：PURPOSE:To verify the diagnostic value of closed chamber thermometry and humidity measurement in normal and dry eye patients. METHODS:In 20 patients (40 eyes) with dry eye and 20 normal sex- and age-matched controls (40 eyes), aged from 11 to 61 years (mean 37.52 yrs, standard deviation, (SD) 14.81) temperature was me...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210301300403
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abstract：PURPOSE:We aimed to discuss the possible role of developmental embryologic factors in neural crest cells in the aetiology of keratoconus and Fuchs' heterochromic iridocyclitis by presenting this case. CASE REPORT:We diagnosed bilateral keratoconus and unilateral Fuchs' heterochromic iridocyclitis in a 19 year old wome...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210101100114
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abstract：:This prospective study of 123 patients undergoing cataract extraction determined the preoperative and surgical factors predisposing to an exaggerated postoperative inflammatory response. It is important to identify the patients at increased risk of complications requiring additional prophylaxis or more intensive posto...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:In renal failure the incidence of pingueculae is significantly higher than in a comparable control group but there is no evidence that the calcific precipitation in renal failure is of a dystrophic nature. The lime salts are not located within the area of elastotic degeneration, a prerequisite for dystrophic degenerat...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：OBJECTIVE:To assess the role of 10-2 visual field (VF) test in different stages of glaucoma. METHODS:In our prospective comparative study, 24-2 and 10-2 VF tests were done for 115 eyes with different stages of glaucomatous damage or glaucoma suspects. Optical coherence tomography (OCT) was performed in 79 eyes. We com...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
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abstract：PURPOSE:To report a case of optic nerve and dura mater involvement as the first sign of multiple myeloma. METHODS:Case report. RESULTS:A 43-year-old woman presented with a headache and decreased vision in both eyes. Ophthalmic examination revealed anterior uveitis and subretinal mass around the optic nerves with acco...
journal_title：European journal of ophthalmology
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doi：10.5301/ejo.5000489
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abstract：PURPOSE:To describe the natural course of type 2 idiopathic macular telangiectasia (MT) using spectral-domain optical coherence tomography (SD-OCT). METHODS:Analysis of the different stages of progression of type 2 MT during a period of 3 years using multimodal imaging, including SD-OCT correlated with angiographic an...
journal_title：European journal of ophthalmology
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doi：10.5301/ejo.5000363
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abstract：PURPOSE:To evaluate changes in anterior chamber morphology with the Pentacam anterior segment analyzer and gonioscopy after laser peripheral iridotomy (LPI) in patients with primary angle closure glaucoma and narrow angle and to compare central corneal thickness measurements performed with Pentacam and ultrasound pachy...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067211002000211
更新日期：2010-03-01 00:00:00
abstract：PURPOSE:To evaluate the efficiency and safety of refractive lens exchange for the correction of high myopia. METHODS:We made a prospective study of the results of refractive lens exchange in 72 eyes that had undergone this surgical procedure between January 1996 and January 2001. Lens extraction by phacoemulsification...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210201200507
更新日期：2002-09-01 00:00:00
abstract：INTRODUCTION::The purpose of the study was to estimate the number of people with diabetes mellitus, the prevalence of diabetes mellitus and the prevalence of blindness and severe visual impairment among people with diabetes mellitus in Hungary based on our recent national representative survey. METHODS::Altogether 105...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,多中心研究
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更新日期：2019-03-01 00:00:00
abstract：PURPOSE:To present an unusual case of simultaneous bilateral retinal detachment (RD) following a coronary artery bypass graft in a patient with acute myocardial infarction (AMI). METHODS:A 78-year-old man was first seen for bilateral sudden visual loss after surgical treatment of AMI. The patient underwent ultrasound ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210701700530
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abstract：PURPOSE:To evaluate persistency (time on initial therapy) and the clinical impact of latanoprost versus beta-blocker monotherapy in treating glaucoma. METHODS:This observational, multicenter, retrospective medical chart review study conducted in four European countries included patients with primary open-angle glaucom...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.1177/112067210301304s03
更新日期：2003-07-01 00:00:00
abstract：PURPOSE:To study sex differences in corneal biomechanical parameters in Egypt as regards to corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and corneal-compensated intraocular pressure (IOPcc). METHODS:This is a cross-sectional observational study that include...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000572
更新日期：2015-09-01 00:00:00
abstract：PURPOSE:To examine the nature and frequency of ocular side effects due to systemic target therapy with BRAF and MEK inhibitors as well as immunotherapy with cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed cell death 1 (PD-1) monoclonal antibodies used in the treatment of cutaneous malignant melanoma (CMM). DE...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120930688
更新日期：2020-05-31 00:00:00
abstract：PURPOSE:To report one case of multiple and bilateral choroidal tumors from a poorly differentiated small cell neuroendocrine carcinoma of unknown primary. METHODS:The case of a 30-years-old white female who developed multiple and bilateral choroidal tumors from a poorly differentiated small cell neuroendocrine carcino...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/EJO.2008.3247
更新日期：2005-01-01 00:00:00
abstract：PURPOSE:To report a corneal transplant complication associated with intracameral recombinant tissue plasminogen activator (rTPA) treatment of postoperative fibrin reaction. METHODS:In a 71-year-old patient, a triple procedure was performed for perforated rheumatic ulcer and secondary cataract. RESULTS:A dense band ke...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210701700328
更新日期：2007-05-01 00:00:00
abstract：PURPOSE:To describe the demographics and clinical characteristics of work-related open-globe injuries (OGIs) at a level I trauma center over a 10-year period. METHODS:Retrospective series. RESULTS:A total of 183 eyes with work-related OGIs were identified. The majority of injuries occurred in men (96.7%). The anatomi...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000209
更新日期：2013-03-01 00:00:00
abstract：PURPOSE:To compare the symptoms, signs, and results of objective tests for dry eye syndrome (DES) in type 1 diabetes mellitus (T1DM) patients and controls. METHODS:A total of 104 children with T1DM and 104 age- and sex-matched controls were compared in terms of the symptoms, signs, and results of objective tests for D...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210701700601
更新日期：2007-11-01 00:00:00
abstract：PURPOSE:To compare the results of viscocanalostomy with and without mitomycin-C (MMC). METHODS:Retrospective results of 15 standard viscocanalostomy (VCO) operations (Group 1) were compared with the prospective results of 15 VCO operations performed with intraoperative adjunctive MMC (Group 2). MMC (0.2 mg/mL) was app...
journal_title：European journal of ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1177/112067210501500204
更新日期：2005-03-01 00:00:00
abstract：PURPOSE:Parry-Romberg syndrome (PRS) is a rare disease of unknown etiology and pathogenesis, characterized by progressive hemifacial atrophy. Diverse ocular manifestations were reported in association with PRS, including enophthalmos, lid retraction, blepharoptosis, restrictive strabismus, ocular motor nerve dysfunctio...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067211002000132
更新日期：2010-01-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy of AcrySof SN60WF aspheric intraocular lens (IOL) in decreasing spherical aberration and total higher order aberrations (HOAs) after cataract surgery compared to the spherical SN60AT lens. METHODS:Wavefront analysis was conducted on 28 eyes of 28 patients that underwent un-complicated ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210701700307
更新日期：2007-05-01 00:00:00
abstract：PURPOSE:To evaluate the efficacy and safety of needle revision and examine factors predictive of failure. METHODS:In total, 157 eyes of 131 patients that underwent needle revision augmented with either 5-fluorouracil or betamethasone for trabeculectomy failure were included in this retrospective study. Complete failur...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672119830861
更新日期：2020-03-01 00:00:00
abstract：PURPOSE:To determine the visual outcome, intraocular lens (IOL) stability and posterior capsule opacification (PCO) rate of a hydrophobic acrylic intraocular lens. SETTING:Vienna Institute for Research in Ocular Surgery, Hanusch Hospital, Vienna, Austria. DESIGN:This double-masked randomised study included patients w...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120960591
更新日期：2020-09-29 00:00:00
abstract：PURPOSE:To report transient vitreomacular traction (VMT) syndrome following acute blunt trauma associated with incomplete posterior vitreous detachment. METHODS:The authors present the analysis of 2 eyes of consecutive patients with acute VMT following mild blunt trauma. Both patients reported a sudden decrease in vis...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/EJO.2011.6425
更新日期：2011-09-01 00:00:00
abstract：PURPOSE:Ibopamine is a prodrug of N-methyldopamine that has a non-cycloplegic mydriatic action due to its alpha-adrenergic properties and is able to induce, when topically given, a transient increase of intraocular pressure (IOP) in eyes with hydrodynamic disorders. METHODS:This is a randomized, crossover, open-labele...
journal_title：European journal of ophthalmology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：2004-11-01 00:00:00
abstract：PURPOSE:Dacryocystorhinostomy (DCR) is the standard surgical treatment for adult nasolacrimal duct obstruction. There have been relatively few studies of closed nasolacrimal duct intubation in adults. The aim of this study was to determine rates of anatomic patency following this procedure. METHODS:The authors carried...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210701700402
更新日期：2007-07-01 00:00:00
abstract：PURPOSE:To analyze angiographic changes in choroidal neovascular membranes (CNVM) after strontium-plaque (90Sr) irradiation for exudative age-related macular degeneration (AMD) using masked measurement of the CNVM areas and a masked subjective comparison of CNVM size and leakage. METHODS:We studied the baseline, 3, 6,...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/EJO.2008.4739
更新日期：2001-07-01 00:00:00
abstract：PURPOSE:To compare the IOP readings of an ocular blood flow (OBF) tonograph (OBF Labs UK Ltd) with Goldmann applanation tonometry. METHODS:194 patients were studied. In group 1, the software version 8.2 of the OBF tonograph was used in 214 eyes of 107 patients and in group 2, the 11.2 version of the tonograph was used...
journal_title：European journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1998-07-01 00:00:00
abstract：PURPOSE:Literature regarding different superior oblique (SO) weakening procedures showed variable results. Here, we aim to evaluate the effect of a novel superior oblique tendon suture lengthening (SOSL) procedure on weakening of SO in patients with A-pattern exotropia associated with dissociated vertical deviation and...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120968726
更新日期：2020-11-11 00:00:00
abstract：PURPOSE:To evaluate the safety of a foldable acrylic single-piece intraocular lens (IOL) in cases of complicated cataract surgery and sulcus implantation. The setting was University and private anterior segment surgery practices. METHODS:In this observational case series study, 13 eyes of 13 patients were included aft...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000160
更新日期：2012-11-01 00:00:00
