Fibrin reaction after uveitic cataract surgery: treatment and prevention.

Abstract:

PURPOSE:To describe the management with intracameral recombinant tissue plasminogen activator (rtPA) of severe fibrin effusion after phacoemulsification, and its prevention with sustained-release dexamethasone intravitreal implant. METHODS:A 59-year-old man with chronic HLA-B27-associated uveitis underwent phacoemulsification followed by a sustained-release dexamethasone intravitreal implant. RESULTS:A postoperative severe fibrin reaction was completely resolved after intracameral injection of rtPA. At the time of the phacoemulsification of the fellow eye, a dexamethasone implant was injected 5 days prior to surgery, with no fibrin formation. CONCLUSIONS:Intracameral rtPA may be successfully used in the management of severe fibrin reaction. Dexamethasone intravitreal implant to control postoperative inflammation may take several days until it achieves high concentrations in the vitreous.

journal_name

Eur J Ophthalmol

authors

da Rocha Lima B,Pichi F,Nucci P,Srivastava SK,Lowder CY

doi

10.5301/ejo.5000442

subject

Has Abstract

pub_date

2014-07-01 00:00:00

pages

626-8

issue

4

eissn

1120-6721

issn

1724-6016

pii

5420AB1C-4183-422B-933F-83C86EAF5DD8

journal_volume

24

pub_type

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