Optical coherence tomography angiography in age-related macular degeneration: The game changer.

Abstract:

:Optical coherence tomography angiography is one of the biggest advances in ophthalmic imaging. It enables a depth-resolved assessment of the retinal and choroidal blood flow, far exceeding the levels of detail commonly obtained with dye angiographies. One of the first applications of optical coherence tomography angiography was in detecting the presence of choroidal neovascularization in age-related macular degeneration and establishing its position in relation to the retinal pigmented epithelium and Bruch's membrane, and thereby classifying the CNV as type 1, type 2, type 3, or mixed lesions. Optical coherence tomography angiograms, due to the longer wavelength used by optical coherence tomography, showed a more distinct choroidal neovascularization vascular pattern than fluorescein angiography, since there is less suffering from light scattering or is less obscured by overlying subretinal hemorrhages or exudation. Qualitative and quantitative assessments of optical coherence tomography angiography findings in exudative and nonexudative age-related macular degeneration have been largely investigated within the past 3 years both in clinical and experimental settings. This review constitutes an up-to-date of all the potential applications of optical coherence tomography angiography in age-related macular degeneration in order to better understand how to translate its theoretical usefulness into the current clinical practice.

journal_name

Eur J Ophthalmol

authors

Lupidi M,Cerquaglia A,Chhablani J,Fiore T,Singh SR,Cardillo Piccolino F,Corbucci R,Coscas F,Coscas G,Cagini C

doi

10.1177/1120672118766807

subject

Has Abstract

pub_date

2018-07-01 00:00:00

pages

349-357

issue

4

eissn

1120-6721

issn

1724-6016

journal_volume

28

pub_type

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