Abstract:
PURPOSE:Malignant melanoma associated with a blue nevus is a rare diagnosis. Additionally, only a handful of cases of malignant melanoma associated with blue nevi involving the ocular structures have been reported. We report a probable case of malignant melanoma associated with a blue nevus with metastasis to multiple bilateral ocular structures. METHODS:Observational case report. RESULTS:We report a case of a 27-year-old man with lymph node biopsy-proven malignant melanoma as well as a separate skin biopsy of a blue nevus, who developed multiple bilateral pigmented ocular lesions on the sclera, iris, trabecular meshwork, and choroid. CONCLUSIONS:Although ocular histopathologic evidence could not be obtained, our case likely represents a case of explosive widespread metastasis probably originating from a blue nevus of unknown location, which involved both eyes and adnexae.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Kelmenson AT,Grover Sdoi
10.5301/EJO.2011.6375subject
Has Abstractpub_date
2011-09-01 00:00:00pages
671-3issue
5eissn
1120-6721issn
1724-6016pii
DC7935B4-9AA5-4CD6-82F3-DA8CDDB7A457journal_volume
21pub_type
杂志文章abstract:PURPOSE:Mutations in the ABCA4 gene result in a broad spectrum of severe retinal degeneration, including Stargardt macular dystrophy, fundus flavimaculatus, autosomal recessive retinitis pigmentosa, and cone-rod dystrophy. In addition to the detection of well-characterized mutations, genetic testing frequently yields n...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5001019
更新日期:2018-01-01 00:00:00
abstract:PURPOSE:To compare topographic indices of surface regularity in dry eye patients and in normal subjects (controls) and to investigate the short-term effect of lacrimal punctal plugs on these indices in dry eye patients. METHODS:The surface regularity index (SRI) and surface asymmetry index (SAI) of the TMS-2 corneal t...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100202
更新日期:2001-04-01 00:00:00
abstract:PURPOSE:To compare retinal nerve fiber layer thickness (RNFLT) and inner macula thickness changes measured with Fourier-domain optical coherence tomography (FD-OCT) and scanning laser polarimetry during the course of acute optic neuritis (ON). METHODS:Nine eyes of 7 consecutive patients with multiple sclerosis (MS) we...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2010.5844
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The aim of this article was to study the lower punctum parameters in patients with acquired punctal stenosis using spectral-domain anterior segment optical coherence tomography. SUBJECTS/METHODS:This was a prospective nonrandomized study that included two groups. Group 1 was composed of 32 puncta...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119871396
更新日期:2019-09-06 00:00:00
abstract:PURPOSE:To investigate color perception and contrast sensitivity with and without additional glare in pseudophakic patients with a conventional intraocular lens (IOL) in one eye and a blue light-filtering IOL in the fellow eye. METHODS:Twenty-three bilaterally pseudophakic patients with a conventional IOL (AcrySof SA6...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210901900210
更新日期:2009-03-01 00:00:00
abstract:PURPOSE:The imaging quality provided by a piggyback integrated by a monofocal intraocular lens (IOL) + a bifocal IOL of zero power and +3.75 diopters of addition is compared with the optics quality of a simple multifocal IOL of the same power and addition. METHODS:The imaging quality was evaluated by determining the m...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000109
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:To evaluate the safety of a foldable acrylic single-piece intraocular lens (IOL) in cases of complicated cataract surgery and sulcus implantation. The setting was University and private anterior segment surgery practices. METHODS:In this observational case series study, 13 eyes of 13 patients were included aft...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000160
更新日期:2012-11-01 00:00:00
abstract::Ultrasound tissue characterization parameters of size and acoustic concentration can be used to sub-classify uveal melanoma and estimate the patient's risk of death. Histologically determined microcirculation patterns have also been found to sub-classify uveal melanoma and predict patient's risk of death. This study e...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVE OF THE STUDY:Inborn lens opacity is the most frequent cause of childhood blindness. In this study, we aimed to define the presumed genetic cause of a congenital cataract present in a Mauritanian family over the last nine generations. METHODS:A family history of the disease and eye examination were carried ou...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672118804757
更新日期:2019-11-01 00:00:00
abstract::Cone-rod dystrophy (CORD) is one of the inherited retinal diseases that result in central visual field deterioration and decreased visual acuity (VA). In CORD patients, impaired photoreceptor cells are observed as the disruption of ellipsoid zone (EZ) on optical coherence tomography (OCT) images. In the present study,...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672121990561
更新日期:2021-01-26 00:00:00
abstract:PURPOSE:This study was performed to test the diagnostic capability of the minimum rim width compared to peripapillary retinal nerve fiber layer thickness in patients with glaucoma. METHODS:A case control, observer masked study, was conducted. Minimum rim width and retinal nerve fiber layer thickness were assessed usin...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672117750057
更新日期:2018-07-01 00:00:00
abstract:PURPOSE:To compare higher order aberrations (HOA) in AcrySof SN60AT and Acrysof IQ SN60WF intraocular lenses (IOLs) and natural crystalline lenses in an age-matched population. METHODS:Sixty-nine eyes of 55 patients were examined. Group I included AcrySof spheric lenses, group II AcrySof aspheric lenses, and group III...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800511
更新日期:2008-09-01 00:00:00
abstract::We sent questionnaires to 424 retina specialists in order to compile information on the use of fluorescein angiography in pregnant women. Four-hundred and three specialists responded. Of these, 313 (78%) had never performed fluorescein angiography on a pregnant woman. Ninety specialists (22%) had performed at least on...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1991-04-01 00:00:00
abstract::Electroretinogram (ERG) changes with age have been studied widely, but there is no general agreement about the age at which ERG parameters reach adult values. We studied 296 eyes from 148 healthy subjects, divided into 14 age groups, ranging from 1 week to 21 years. Although most of the maturational changes or ERG tak...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:Anthrax is a rare infection transmitted to humans from animals or animal products. In cutaneous anthrax it may produce lesions of the eyelids which can lead to cicatricial ectropion. METHODS:We examined three women and five men with anthrax of the eyelids. Intravenous penicillin G was used alone as therapy. R...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100212
更新日期:2001-04-01 00:00:00
abstract:PURPOSE:To investigate the mean values of intraocular pressure (IOP) measured with noncontact tonometer (NCT) and evaluate the factors that may affect IOP. METHODS:A total of 850 subjects who were admitted to our clinic between March 2005 and February 2006 were recruited for the study. Subjects having blepharitis, con...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210901900109
更新日期:2009-01-01 00:00:00
abstract::Non-arteritic anterior ischemic optic neuropathy (NAION) is characterized by the progressive and irreversible death of retinal ganglion cells (RGCs) which is caused by the insufficient blood supply to the optic nerve (ON) head. At present, hormone therapy is used to reduce optic edema, followed by nerve nutrition ther...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120974283
更新日期:2020-11-21 00:00:00
abstract:PURPOSE:To evaluate the additional therapeutic effect of single intravitreal bevacizumab injection on standard laser treatment in the management of proliferative diabetic retinopathy. METHODS:A prospective, fellow-eye sham controlled clinical trial was conducted on 80 eyes of 40 high-risk characteristic proliferative ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1177/112067210801800215
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:To evaluate visual and anatomic outcomes following pars plana vitrectomy and intravitreal or subretinal tissue plasminogen activator for submacular hemorrhage in patients with age-related macular degeneration. METHODS:This was a retrospective study on patients with a minimum follow-up of 12 months undertaken a...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119891625
更新日期:2019-12-09 00:00:00
abstract:PURPOSE:To evaluate the changes in retinal nerve fiber layer thickness (RNFLT), ganglion cell layer thickness (GCLT), retinal thickness (RT), and subfoveal choroidal thickness (SFCT) in eyes that received pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling for idiopathic macular hole (IMH) and to ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000851
更新日期:2017-05-11 00:00:00
abstract:PURPOSE:Choroidal neovascularization (CNV) is a rare complication after laser photocoagulation for disorders such as central serous chorioretinopathy (CSC). METHODS:We report 2 patients who developed CNV after laser treatment for persistent CSC and were treated by 3 1.25-mg intravitreal injections of bevacizumab in 1-...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000036
更新日期:2012-05-01 00:00:00
abstract:PURPOSE:To evaluate the safety and efficacy of intravitreal injections of crystalline triamcinolone acetonide as an adjunctive procedure in pars plana vitrectomy for proliferative diabetic retinopathy. METHODS:This nonrandomized comparative study included 30 patients (32 eyes) who underwent standardized pars plana vit...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1177/112067210301300508
更新日期:2003-06-01 00:00:00
abstract::A 50-year-old white man complained of "inflammation" of his right eyelid since January 1989. In June 1990, he had undergone a gastrectomy for an adenocarcinoma of the stomach. In August 1990, his right eye showed a painless, firm infiltration of the upper and lower lid, ulceration and loss of eyelashes of the upper li...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of AcrySof SN60WF aspheric intraocular lens (IOL) in decreasing spherical aberration and total higher order aberrations (HOAs) after cataract surgery compared to the spherical SN60AT lens. METHODS:Wavefront analysis was conducted on 28 eyes of 28 patients that underwent un-complicated ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700307
更新日期:2007-05-01 00:00:00
abstract:PURPOSE:To investigate the efficacy of intravitreal dexamethasone implants (DEX) after anti-VEGF failure in retinal vein occlusion macular oedema. METHODS:Retrospective cohort study of DEX implant (0.7 mg) given after anti-VEGF 'failure'. Switch to DEX occurred if a ⩽ +5 ETDRS letter gain and ⩽20% reduction in central...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120978355
更新日期:2020-12-27 00:00:00
abstract:PURPOSE:To evaluate the effect of IOP lowering on the capillary density of optic nerve head and retinal nerve fiber layer in patients with primary open angle glaucoma. METHODS:Twenty eyes of 14 glaucomatous patients and 15 eyes of nine normal patients were enrolled. The most appropriate hypotonic treatment was applied...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120967233
更新日期:2020-10-29 00:00:00
abstract:PURPOSE:To describe eye health-care services provided by in patient Departments of Ophthalmology in Hungary as of 1998. METHODS:A standardised questionnaire was sent to all Hungarian in-patient ophthalmic departments. The response rate was 100%, and data from six university departments and 56 hospitals with ophthalmic...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210201200310
更新日期:2002-05-01 00:00:00
abstract:PURPOSE:A pilot study was carried out to evaluate the practicality, reliability, and validity of an objective structured clinical examination (OSCE) for assessing the clinical skills and abilities of specialists in ophthalmology. METHODS:Ten unfolded OSCE style, criterion referenced questions were asked to nine candid...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210601600415
更新日期:2006-07-01 00:00:00
abstract:PURPOSE:To investigate the ocular and orbital complications observed in children treated for retinoblastoma. SUBJECTS AND METHODS:We retrospectively studied 73 children (39 boys, 34 girls) suffering from retinoblastoma. Thirty-six had bilateral tumor and 37 unilateral disease for a total of 109 eyes affected. The foll...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1998-04-01 00:00:00
abstract::Most cases of retinoblastoma are diagnosed before the age of 5 years. The cases in older age groups can have variable presentations leading to misdiagnosis and management challenges. We report a case of retinoblastoma in an 8-year-old female who was primarily referred as a case of sympathetic ophthalmia due to a co-in...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120939388
更新日期:2020-07-02 00:00:00