Abstract:
:Diseases of the optic nerve head involving changes in blood flow are common. However, the pathophysiology is not always fully understood. Several non-invasive methods for measuring optic nerve head blood flow are available, but currently no gold standard has been established. Methods for measuring blood flow in optic neuropathies including colour Doppler imaging, retinal function imager, optical coherence tomography angiography and laser speckle flowgraphy are reviewed. Ultrasound colour Doppler imaging is a fast measurement technique where several different parameters, especially the blood flow velocity, can be calculated. Though used for many years in ophthalmology, its use is not standardized and it requires significant observer skills. The retinal function imager is a direct method where the haemoglobin in erythrocytes is visualized and blood flow velocities in retinal vessels are calculated from a series of photos. The technique is not suitable for direct measurement of blood flow within the optic nerve head. Laser speckle flowgraphy uses a laser light which creates a light scatter pattern in the tissue. Particles moving in the area causes changes in the speckle pattern from which a relative blood flow can be estimated. It is, however, not known whether optic nerve head microcirculation is measurable with the technique. Optical coherence tomography angiography uses multiple scans to evaluate blood flow with good reproducibility but often problems with artefacts. The technique is continuously being refined and increasingly used in research as a tool for the study of blood flow in retinopathies and optic neuropathies. Most of the conducted studies are based on small sample sizes, but some of the methods show promising results in an optic nerve head blood flow research setting. Further and larger studies are required to provide standardized and comparable measurements before one or more of the methods can be considered clinical helpful in daily practice.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Vosborg F,Malmqvist L,Hamann Sdoi
10.1177/1120672119858891subject
Has Abstractpub_date
2020-03-01 00:00:00pages
235-244issue
2eissn
1120-6721issn
1724-6016journal_volume
30pub_type
杂志文章,评审abstract:PURPOSE:To report the results of corneal collagen crosslinking (CXL) in a patient with corneal ectasia developed after excimer laser-assisted lamellar keratoplasty for keratoconus and a secondary photorefractive keratectomy (PRK) for residual refractive error. METHODS:A 33-year-old woman, who had originally been treat...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000019
更新日期:2012-03-01 00:00:00
abstract:AIM:To review published literature concerning cataract surgery and dry eye disease (DED). METHODS:A search was undertaken using the following: PubMed (all years), Web of Science (all years), Ovid MEDLINE(R) (1946 to 12 December 2019), Ovid MEDLINE(R) Daily Update 10 December 2019, MEDLINE and MEDLINE non-indexed items...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1177/1120672120929958
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To compare the performance of two different microcatheter systems, iTrack™ 250A and Glaucolight, in ab externo canaloplasty in three major categories: intraocular pressure reduction, drug therapy reintroduction, and evaluation of viscodilation over distension of the inner wall of Schlemm's canal. METHODS:A tot...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119833547
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy, safety, and tolerability of Timogel® preservative-free once daily compared to timolol 0.5% ophthalmic solution bid in patients with ocular hypertension (OHT) and patients with primary open-angle glaucoma (POAG). METHODS:A total of 75 patients with OHT and patients with POAG treated wi...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000006
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:To describe the demographics and clinical characteristics of work-related open-globe injuries (OGIs) at a level I trauma center over a 10-year period. METHODS:Retrospective series. RESULTS:A total of 183 eyes with work-related OGIs were identified. The majority of injuries occurred in men (96.7%). The anatomi...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000209
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:To report a case of optic nerve and dura mater involvement as the first sign of multiple myeloma. METHODS:Case report. RESULTS:A 43-year-old woman presented with a headache and decreased vision in both eyes. Ophthalmic examination revealed anterior uveitis and subretinal mass around the optic nerves with acco...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000489
更新日期:2015-01-01 00:00:00
abstract::Although it is now possible to significantly reduce the incidence of blindness secondary to diabetes mellitus, large numbers of diabetic patients still experience visual loss due to retinal complications of the disease. This implies that protocols for the diagnosis and treatment of diabetic retinopathy used in the var...
journal_title:European journal of ophthalmology
pub_type: 社论
doi:10.1177/112067219900900302
更新日期:1999-07-01 00:00:00
abstract::Two cases of idiopathic sclerochoroidal calcification are reported with follow-up of two and ten years. In addition we have reviewed 102 cases of choroidal osteoma, including six misleading case reports which actually described idiopathic sclerochoroidal calcification and not choroidal osteoma. Clinical manifestation ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract::Purpose. Extraocular muscle (EOM) pulleys are important in eye movement physiology and may play a role in the outcome of strabismus surgery. Few studies have evaluated "normal" position of EOM pulleys. We sought to assess intraoperatively medial rectus (MR) pulley location and variations in a prospective observational...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000187
更新日期:2013-01-21 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1177/112067210901900317
更新日期:2009-05-01 00:00:00
abstract::Idiopathic macular holes have long been considered to be a stable, untreatable condition with little or no chance of spontaneous visual improvement. Within the last few years, surgical intervention has been developed for the management of idiopathic Stage 3 and Stage 4 holes. With pars plana vitrectomy surgery, at lea...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract:PURPOSE:To evaluate and compare the glaucoma discrimination ability of macula, macular ganglion cell complex (mGCC), and peripapillary nerve fiber layer (ppNFL) thickness in Chinese patients using Fourier-domain optical coherence tomography (FD-OCT). METHODS:A total of 64 normal subjects (N), 47 glaucoma suspects (GS)...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000131
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:To evaluate the changes of corneal biomechanics and the intraocular pressure during pregnancy in a Chinese healthy female population. METHODS:A total of 222 unrelated Chinese females were recruited: 52 non-pregnant, 15 pregnant in the first trimester, 68 pregnant in the second trimester, and 87 pregnant in the...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120902034
更新日期:2020-01-27 00:00:00
abstract:PURPOSE:To assess the long-term anatomical and functional results of balloon buckle surgery for rhegmatogenous retinal detachment. PATIENTS AND METHODS:Twenty-five selected detachments with a single break or a group of breaks close together were treated with a temporary parabulbar balloon. Adhesion was obtained with t...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100410
更新日期:2001-10-01 00:00:00
abstract:PURPOSE:To emphasize the demographic and occupational characteristics of ophthalmologists primarily involved in retinopathy of prematurity (ROP) care and to ascertain their practices and preferences. METHODS:A questionnaire was sent to all Turkish ophthalmologists known to be primarily involved in ROP. They were asked...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000272
更新日期:2013-07-01 00:00:00
abstract:PURPOSE:To evaluate the changes in retinal nerve fiber layer thickness (RNFLT), ganglion cell layer thickness (GCLT), retinal thickness (RT), and subfoveal choroidal thickness (SFCT) in eyes that received pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling for idiopathic macular hole (IMH) and to ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000851
更新日期:2017-05-11 00:00:00
abstract:PURPOSE:The purpose of this paper is to demonstrate a case of bilateral complete avulsion of the globes following maxillofacial trauma. METHODS:A 23-year-old man with bilateral complete globe avulsion following a maxillofacial trauma. Both globes were luxated out of the orbit and suspended on the skin of the upper lid...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210501500119
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To compare ocular findings in eyes with primary open-angle glaucoma (POAG) and exfoliation glaucoma (EG) at the time of diagnosis when identical diagnostic criteria for glaucoma were applied. METHODS:We conducted a study on records of 519 consecutive, unselected patients with chronic glaucoma filing for cost-f...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000516
更新日期:2015-03-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1177/1120672117754168
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:To evaluate the safety and efficacy of intravitreal injections of crystalline triamcinolone acetonide as an adjunctive procedure in pars plana vitrectomy for proliferative diabetic retinopathy. METHODS:This nonrandomized comparative study included 30 patients (32 eyes) who underwent standardized pars plana vit...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1177/112067210301300508
更新日期:2003-06-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800628
更新日期:2008-11-01 00:00:00
abstract:PURPOSE:To report the outcome of a single intravitreal triamcinolone acetonide (IVTA) injection as an adjunctive treatment with systemic medication for refractory uveitic cystoid macular edema (CME). METHODS:This was a retrospective, noncomparative, interventional case series. Medical records of 25 patients (35 eyes) ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2010.6062
更新日期:2011-01-01 00:00:00
abstract:PURPOSE:To evaluate choroidal thickness, macular thickness, and peripapillary retinal nerve fiber layer (RNFL) thickness in amblyopic eyes compared to fellow and normal control eyes using high-definition spectral-domain optical coherence tomography (SD-OCT). METHODS:Fifty-four without any systemic problem and ocular d...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000594
更新日期:2015-09-01 00:00:00
abstract::The objectives of this study were two-fold: to identify tear histamine content and its relationship to changes in tear histaminase activity during the early (EPR) and late phases (LPR) of the allergic reaction induced by a conjunctival provocation test (CPT) and to evaluate the effects of lodoxamide on histamine relea...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-04-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of symmetric bilateral medial rectus recession in large-angle esotropic Duane retraction syndrome (DRS) with moderate to severe globe retraction. METHODS:In a retrospective study, medical reports of 30 patients with esotropia of equal or more than 20 prism diopters (pd) and moderate to...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120968731
更新日期:2020-11-04 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1177/112067210301304s03
更新日期:2003-07-01 00:00:00
abstract:PURPOSE:To report clinical and confocal microscopy features of late-onset Candida albicans keratitis after Descemet stripping automated keratoplasty (DSAEK). METHODS:We performed clinical and confocal scan on a patient who underwent DSAEK and phacoemulsification for Fuchs endothelial dystrophy and cataract. RESULTS:A...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.6228
更新日期:2011-07-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:
更新日期:1998-10-01 00:00:00
abstract:PURPOSE:To compare the clinical results of heparin surface modified (HSM) hydrophilic acrylic intraocular lens (IOL) with those of hydrophobic acrylic IOL. METHODS:One hundred patients with cataract were randomized to receive one of acrylic foldable IOLs after phacoemulsification: HSM hydrophilic acrylic IOL (n=50) Bi...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1177/112067210801800311
更新日期:2008-05-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700510
更新日期:2007-09-01 00:00:00