Changes of vascular endothelial growth factor after vitrectomy for macular edema secondary to retinal vein occlusion.


PURPOSE:To examine whether vitrectomy combined with retinal photocoagulation reduces the vitreous level of vascular endothelial growth factor (VEGF) in patients with macular edema associated with retinal vein occlusion (RVO). METHODS:The authors measured VEGF levels in vitreous samples from four eyes of four patients with RVO during vitrectomy and fluid samples obtained during revitrectomy 3 to 9 months postoperatively for complications: an epiretinal membrane in two patients, macular holes in one patient, and vitreous hemorrhage in one patient. During vitrectomy, retinal photocoagulation was performed on the ischemic region of the retina in all cases (mean of 510 shots). RESULTS:In four eyes with RVO, there was a difference in the vitreous VEGF levels between the vitreous samples obtained during vitrectomy (mean of 2692 pg/mL, range of 15.6-9040 pg/mL) and the fluid samples obtained at the time of revitrectomy (mean of 947 pg/mL, range of 15.6-3430 pg/mL). CONCLUSIONS:The results suggest that the vitreous levels of VEGF may be reduced by vitrectomy combined with retinal photocoagulation for macular edema with RVO. It may be important to reduce the vitreous levels of VEGF by vitrectomy and retinal photocoagulation for ischemic retina in macular edema with RVO.


Eur J Ophthalmol


Noma H,Funatsu H,Mimura T,Hori S




Has Abstract


2008-11-01 00:00:00












  • Comparison of primary open-angle glaucoma and exfoliation glaucoma at diagnosis.

    abstract:PURPOSE:To compare ocular findings in eyes with primary open-angle glaucoma (POAG) and exfoliation glaucoma (EG) at the time of diagnosis when identical diagnostic criteria for glaucoma were applied. METHODS:We conducted a study on records of 519 consecutive, unselected patients with chronic glaucoma filing for cost-f...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Tarkkanen AH,Kivelä TT

    更新日期:2015-03-01 00:00:00

  • Oculofacial alterations in NBAS-SOPH like mutations: Case report.

    abstract:PURPOSE:To describe the clinical features of a rare case of NBAS-SOPH-like mutations; to emphasize special aspects of the ocular and oro-facial regions. METHODS:Case report. CASE DESCRIPTION:We present a 5-year-old girl initially examined for her dysmorphic features, mental delay, strabismus, and high myopia. During ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Nucci F,Lembo A,Farronato M,Farronato G,Nucci P,Serafino M

    更新日期:2020-03-01 00:00:00

  • Isolated unilateral abducens cranial nerve palsy: a rare presentation of pituitary apoplexy.

    abstract:PURPOSE:To describe a rare presentation of pituitary apoplexy as unilateral abducens nerve palsy demonstrating the various presentations of the condition. METHODS:Case report. RESULTS:A 48-year-old man presented with isolated right abducens nerve palsy. Magnetic resonance imaging showed a large pituitary macroadenoma...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Matti AI,Rudkin AK,Lee AW,Chen CS

    更新日期:2010-01-01 00:00:00

  • Regression patterns of choroidal melanoma: After palladium-103 (103Pd) plaque brachytherapy.

    abstract:PURPOSE::To describe the patterns of regression of choroidal melanoma after treatment with plaque brachytherapy. METHODS::Retrospective interventional case series including 170 consecutive patients treated with 103Pd eye plaque radiation for choroidal melanoma. Outcome measures were changes in tumor thickness, surface...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Maheshwari A,Finger PT

    更新日期:2018-11-01 00:00:00

  • Surgical management of idiopathic macular holes.

    abstract::Idiopathic macular holes have long been considered to be a stable, untreatable condition with little or no chance of spontaneous visual improvement. Within the last few years, surgical intervention has been developed for the management of idiopathic Stage 3 and Stage 4 holes. With pars plana vitrectomy surgery, at lea...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,评审


    authors: Del Priore LV

    更新日期:1994-01-01 00:00:00

  • Prophylaxis against infection in cataract surgery: a survey of routine practice.

    abstract:PURPOSE:To survey the routine practice of consultant ophthalmic surgeons in the United Kingdom in preventing postoperative endophthalmitis following cataract surgery. METHODS:This is a cross-sectional questionnaire-based study. A questionnaire was sent to consultant ophthalmic surgeons in university teaching hospital ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,多中心研究


    authors: Ang GS,Barras CW

    更新日期:2006-05-01 00:00:00

  • Retinopathy of prematurity: screening guidelines need to be reevaluated for developing countries.

    abstract:PURPOSE:Timely screening of premature babies is an important initial step in the management of retinopathy of prematurity (ROP) as earlier treatment results in improved visual prognosis. Screening criteria for ROP currently recommended by the American Academy of Pediatrics may not be applicable in developing countries....

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Başmak H,Niyaz L,Sahin A,Erol N,Gürsoy HH

    更新日期:2010-07-01 00:00:00

  • Evaluation of transforming growth factor and vascular endothelial growth factor polymorphisms in Taiwan Chinese patients with pterygium.

    abstract:PURPOSE:Pterygium is an invasive and highly vascularized growth, thought to arise from activated and proliferating limbal epithelial stem cells. Epidemiologic studies have found the increase of active angiogenic and epithelial growth factors in pterygia, and implicated that these molecules could be involved directly or...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Bau DT,Chiang CC,Tsai YY,Lee CC,Tsai Y,Lin CC,Tsai CH,Tsai FJ

    更新日期:2008-01-01 00:00:00

  • Dacryo-fornix-rhinostomy with two flaps.

    abstract::The two most frequent sites of obstruction of the lacrimal pathways are under the lacrimal sac, in the ductus lacrimonasalis, and over the lacrimal sac, in the canaliculi. The obstruction of the first type already has a satisfactory solution with the different forms of dacryo-cysto-rhinostomies. Obstruction of the sec...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Murube del Castillo J,Martinez Baradas A,Hernandez King J,Cruz Vilella ME,Bahamon Caycedo M

    更新日期:1992-04-01 00:00:00

  • Ranibizumab for persistent diabetic macular edema after bevacizumab treatment.

    abstract:PURPOSE:To evaluate the efficacy of switching from bevacizumab to ranibizumab in patients with diabetic macular edema (DME). METHODS:This was a retrospective study of patients with DME initially treated with bevacizumab and switched to ranibizumab. Visual acuity (VA) and central retinal thickness (CRT) were retrieved ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Katz G,Moisseiev E,Goldenberg D,Moisseiev J,Lomnicky Y,Abend Y,Treister G,Levkovitch-Verbin H

    更新日期:2017-03-10 00:00:00

  • Endophthalmitis associated with fungal keratitis and penetrating injuries in North China.

    abstract:PURPOSE:To report the laboratory findings, management strategies, and visual outcomes of culture-proven exogenous fungal endophthalmitis in North China. METHODS:The microbiological and treatment records of patients with culture-positive exogenous fungal endophthalmitis who visited the Affiliated Hospital of Qingdao Un...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Liu MY,Zhang L,Yin XL,Sun SY

    更新日期:2020-05-01 00:00:00

  • Luxated intraocular lens fixation using anterior chamber slipknot of the haptic to the sclera: a simple procedure to fixate intraocular lens to the sclera.

    abstract:PURPOSE:To describe a technique for suturing a luxated intraocular lens (IOL) in the vitreous cavity directly to the ciliary sulcus using intraocular slipknot without IOL extraction. DESIGN:Noncomparative interventional case series. MATERIALS AND METHODS:A three-port vitrectomy was performed in all cases. According t...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Micelli Ferrari T,Cardascia N,Furino C,Recchimurzo N,Boscia F,Sborgia L

    更新日期:2003-07-01 00:00:00

  • Intravitreal steroid slow-release device replacing repeated intravitreal triamcinolone injections for sympathetic ophthalmia.

    abstract:PURPOSE:To report on the intraocular use of a steroid slow-release device in an attempt to avoid multiple intraocular triamcinolone injections in chronic sympathetic ophthalmia. METHODS:A 47-year-old patient with sympathetic ophthalmia had received 17 intravitreal triamcinolone injections to suppress the uveitis, to i...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Jonas JB,Rensch F

    更新日期:2008-09-01 00:00:00

  • Sulcus implantation of a single-piece foldable acrylic intraocular lens after posterior capsular rupture in cataract surgery.

    abstract:PURPOSE:To evaluate the safety of a foldable acrylic single-piece intraocular lens (IOL) in cases of complicated cataract surgery and sulcus implantation. The setting was University and private anterior segment surgery practices. METHODS:In this observational case series study, 13 eyes of 13 patients were included aft...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Renieri G,Herzog D,Niemann S,Becker M,Kurz S,Thieme H

    更新日期:2012-11-01 00:00:00

  • Specificity of in vivo confocal cornea microscopy in Acanthamoeba keratitis.

    abstract:PURPOSE:To report on the presence of 4 different structures visualized by confocal microscopy in patients whose clinical presentation suggested infection by Acanthamoeba. METHODS:Data and charts of 28 consecutive patients were analyzed in a retrospective study. Four types of structures were recognized by confocal micr...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Füst Á,Tóth J,Simon G,Imre L,Nagy ZZ

    更新日期:2017-01-19 00:00:00

  • Novel ABCA4 mutation leads to loss of a conserved C-terminal motif: implications for predicting pathogenicity based on genetic testing.

    abstract:PURPOSE:Mutations in the ABCA4 gene result in a broad spectrum of severe retinal degeneration, including Stargardt macular dystrophy, fundus flavimaculatus, autosomal recessive retinitis pigmentosa, and cone-rod dystrophy. In addition to the detection of well-characterized mutations, genetic testing frequently yields n...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Wangtiraumnuay N,Capasso J,Tsukikawa M,Levin A,Biswas-Fiss E

    更新日期:2018-01-01 00:00:00

  • Divergent strabismus fixus--a case report.

    abstract::Strabismus fixus is a rare condition and usually is of convergent type in which one or both eyes are anchored in a position of extreme adduction. Convergent type strabismus fixus is considered to be a congenital disorder and a part of congenital extraocular muscle fibrosis syndrome. Villasecca and Martinez described a...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Sharma TK,Grewal JS,MacDonald M

    更新日期:2003-03-01 00:00:00

  • Surgical management of consecutive exotropia: Long-term outcomes.

    abstract:PURPOSE:To compare lateral rectus recession (LRc) and medial rectus advancement (MRadv) for correction of consecutive exotropia (CXT). METHODS:Of the 43 exotropic patients 20 of them underwent LRc (group 1) and 23 of them underwent MRadv (group 2). Postoperative exodrift, strabismic angle, dose effect relationship wer...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Ceylan OM,Oğuz YG,Ayyıldız Ö,Köksal S,Yumuşak E,Mutlu FM

    更新日期:2021-01-09 00:00:00

  • The effects of 2% ibopamine eye drops on the intraocular pressure and pupil motility of patients with open-angle glaucoma.

    abstract:PURPOSE:Ibopamine is a prodrug of N-methyldopamine that has a non-cycloplegic mydriatic action due to its alpha-adrenergic properties and is able to induce, when topically given, a transient increase of intraocular pressure (IOP) in eyes with hydrodynamic disorders. METHODS:This is a randomized, crossover, open-labele...

    journal_title:European journal of ophthalmology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Giuffrè I,Taverniti L,Di Staso S

    更新日期:2004-11-01 00:00:00

  • Evaluation of macular thickness after uncomplicated cataract surgery using optical coherence tomography.

    abstract:PURPOSE:To evaluate central macular thickness (CMT) after cataract surgery in selected groups of patients. 
 METHODS:The study comprised 4 groups-patients with epiretinal membrane, patients with high myopia, patients with diabetes without retinopathy, and healthy subjects-who underwent phacoemulsification and intraocu...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Giansanti F,Bitossi A,Giacomelli G,Virgili G,Pieretti G,Giuntoli M,Abbruzzese G,Menchini U

    更新日期:2013-09-01 00:00:00

  • Comparison of 3 pupillometers for determining scotopic pupil diameter.

    abstract:PURPOSE:The pupil diameter under low ambient illumination is diagnostically valuable for refractive surgery. The aim of study was to compare the NeurOptics® Pupillometer, Sirius®, and Ocular Wavefront Analyser® in determining scotopic pupil diameter. MATERIALS AND METHODS:A total of 96 eyes of 48 subjects were include...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Altan C,Kaya V,Basarir B,Celik U,Azman E,Akar S,Demirok A,Yilmaz OF

    更新日期:2012-11-01 00:00:00

  • Dry eye syndrome in diabetic children.

    abstract:PURPOSE:To compare the symptoms, signs, and results of objective tests for dry eye syndrome (DES) in type 1 diabetes mellitus (T1DM) patients and controls. METHODS:A total of 104 children with T1DM and 104 age- and sex-matched controls were compared in terms of the symptoms, signs, and results of objective tests for D...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Akinci A,Cetinkaya E,Aycan Z

    更新日期:2007-11-01 00:00:00

  • Comparative study of astigmatism through superior and lateral small incisions.

    abstract:PURPOSE:To prospectively compare the clinical results of two cataract surgery procedures through a 4.0-mm incision, differing only in the wound location (superior or lateral). METHODS:168 eyes with cataract were randomly assigned to either procedure. Except for incision location, surgical methods were identical. Uncor...

    journal_title:European journal of ophthalmology

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Mendívil A

    更新日期:1996-10-01 00:00:00

  • Conjunctival scrapings and impression cytology in chronic conjunctivitis. Correlation with microbiology.

    abstract::To assess the utility of exfoliative cytology in the diagnosis of chronic conjunctivitis, we compared its findings with microbiological examination and established the correlation between cytology and microbiology in 32 patients with conjunctivitis lasting four weeks or more, with a nonspecific clinical picture. The m...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Cvenkel B,Globocnik M

    更新日期:1997-01-01 00:00:00

  • Palbebral anthrax.

    abstract:PURPOSE:Anthrax is a rare infection transmitted to humans from animals or animal products. In cutaneous anthrax it may produce lesions of the eyelids which can lead to cicatricial ectropion. METHODS:We examined three women and five men with anthrax of the eyelids. Intravenous penicillin G was used alone as therapy. R...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Celebi S,Aykan U,Alagöz G,Esmerligil S

    更新日期:2001-04-01 00:00:00

  • One-year follow-up of the XEN® implant with mitomycin-C in pseudoexfoliative glaucoma patients.

    abstract:PURPOSE:To evaluate the intraocular pressure-lowering effect, the safety profile, and the success rate of the XEN45 Gel Stent (Allergan, Dublin, Ireland) in patients with pseudoexfoliative glaucoma. METHODS:Retrospective study conducted on patients with pseudoexfoliative glaucoma, with or without cataract, who underwe...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Ibáñez-Muñoz A,Soto-Biforcos VS,Chacón-González M,Rúa-Galisteo O,Arrieta-Los Santos A,Lizuain-Abadía ME,Del Río Mayor JL

    更新日期:2019-05-01 00:00:00

  • SD-OCT stages of progression of type 2 macular telangiectasia in a patient followed for 3 years.

    abstract:PURPOSE:To describe the natural course of type 2 idiopathic macular telangiectasia (MT) using spectral-domain optical coherence tomography (SD-OCT). METHODS:Analysis of the different stages of progression of type 2 MT during a period of 3 years using multimodal imaging, including SD-OCT correlated with angiographic an...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Coscas G,Coscas F,Zucchiatti I,Bandello F,Soubrane G,SouÏed E

    更新日期:2013-11-01 00:00:00

  • Late-onset Candida keratitis after Descemet stripping automated endothelial keratoplasty: clinical and confocal microscopic report.

    abstract:PURPOSE:To report clinical and confocal microscopy features of late-onset Candida albicans keratitis after Descemet stripping automated keratoplasty (DSAEK). METHODS:We performed clinical and confocal scan on a patient who underwent DSAEK and phacoemulsification for Fuchs endothelial dystrophy and cataract. RESULTS:A...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Ortiz-Gomariz A,Higueras-Esteban A,Gutiérrez-Ortega ÁR,González-Méijome JM,Arance-Gil A,Villa-Collar C

    更新日期:2011-07-01 00:00:00

  • Impact of low mesopic contrast sensitivity outcomes in different types of modern multifocal intraocular lenses.

    abstract:PURPOSE:To investigate the low mesopic contrast sensitivity function (LMCSF) of patients implanted with different modern optical bifocal and trifocal designs of multifocal intraocular lenses (mfIOLs). METHODS:This prospective, comparative, nonrandomized consecutive case series included 180 eyes that underwent cataract...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Plaza-Puche AB,Alio JL,Sala E,Mojzis P

    更新日期:2016-11-04 00:00:00

  • Surgical repair of large cyclodialysis clefts.

    abstract:PURPOSE:To describe a new surgical technique to effectively close large (>180 degrees) cyclodialysis clefts. METHODS:Our method involves the use of procedures commonly associated with repair of retinal detachment and complex cataract extraction: phacoemulsification with placement of a capsular tension ring followed by...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章


    authors: Gross JB,Davis GH,Bell NP,Feldman RM,Blieden LS

    更新日期:2017-05-11 00:00:00