Abstract:
PURPOSE:To report the outcome of a single intravitreal triamcinolone acetonide (IVTA) injection as an adjunctive treatment with systemic medication for refractory uveitic cystoid macular edema (CME). METHODS:This was a retrospective, noncomparative, interventional case series. Medical records of 25 patients (35 eyes) with quiescent uveitic CME who were treated with oral immunosuppressive therapy and underwent 4 mg/0.1 mL IVTA injection were reviewed. Data was collected 6 months post-injection and included details of uveitis, best-corrected visual acuity (BCVA), CME, systemic therapy required, and potential complications of IVTA injection. RESULTS:Thirty eyes (85%) responded with improvement in vision. The mean BCVA improvement was 0.33 (from 0.67 to 0.34 logarithm of the minimum angle of resolution; Snellen equivalent, between 2 and 3 lines) (p<0.001), at a mean time of 6.2 weeks (range 2-16). Resolution of CME was achieved in 31 (88%) of the treated eyes. Following initial response to IVTA, CME relapsed in 8 eyes (26%) after a mean time of 4.2 months (range 2.5-5.5). The dosage of oral corticosteroids and/or second-line immunosuppressive agents was able to be reduced or stopped in 22 patients, 29 of 35 eyes (82.8%). The most common adverse effect was increased intraocular pressure, in 17 (49%) of the treated eyes. Steroid-induced cataract was observed in 6 eyes (17%). CONCLUSIONS:Intravitreal triamcinolone acetonide appears to be an effective supplementary tool in the management of CME refractory to systemic immunosuppressive therapy. Retreatment might be required in some and may be associated with elevated intraocular pressure and cataract.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Habot-Wilner Z,Sallam A,Pacheco PA,Do HH,McCluskey P,Lightman Sdoi
10.5301/EJO.2010.6062subject
Has Abstractpub_date
2011-01-01 00:00:00pages
S56-61eissn
1120-6721issn
1724-6016pii
FAF60F5D-AF35-40A4-8BCB-3A28F23F419Ajournal_volume
21 Suppl 6pub_type
杂志文章abstract:PURPOSE:To report a case of central retinal artery occlusion after Descemet membrane reposition by intracameral air. METHODS:An otherwise healthy 60-year-old woman presented with white mature cataract in her left eye. Ocular exam of both eyes was within normal limits. After an uneventful topical phacoemulsification, a...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119870740
更新日期:2019-08-21 00:00:00
abstract:BACKGROUND:Garcinia cambogia contains hydroxycitric acid. Hydroxycitric acid is a potent competitive inhibitor of adenosine triphosphate citrate lyase which is a key enzyme in the synthesis of fatty acids. Hydroxycitric acid also regulates the level of serotonin. In these regards, hydroxycitric acid has been reported t...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119872364
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To investigate the efficacy of intravitreal dexamethasone implants (DEX) after anti-VEGF failure in retinal vein occlusion macular oedema. METHODS:Retrospective cohort study of DEX implant (0.7 mg) given after anti-VEGF 'failure'. Switch to DEX occurred if a ⩽ +5 ETDRS letter gain and ⩽20% reduction in central...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120978355
更新日期:2020-12-27 00:00:00
abstract:PURPOSE:To delineate and discuss a not yet described possible ocular complication of selective intra-arterial chemotherapy (SIAC) for treatment of retinoblastoma. METHODS:A 23-month-old girl with a large unilateral retinoblastoma was treated with repeated SIAC using 5 mg melphalan between July 2010 and January 2012. C...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000393
更新日期:2014-05-01 00:00:00
abstract::Purpose. To compare long-term variability of retinal nerve fiber layer thickness (RNFLT) measurements made with the RTVue-100 Fourier-domain optical coherence tomograph (RTVue-OCT) and scanning laser polarimetry with variable (GDx-VCC) and enhanced (GDx-ECC) corneal compensation. Methods. One eye each of 110 Caucasian...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000178
更新日期:2013-01-21 00:00:00
abstract:PURPOSE:To compare the inhibitory effects of a topical combination product, cromolyn sodium (DSCG) 4% with the antihistamine, chlorpheniramine, with those of topical ketotifen 0.05% on the clinical allergic reaction induced by the conjunctival allergen challenge (CAC). METHODS:Ten allergic but non-active patients were...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/112067210301300202
更新日期:2003-03-01 00:00:00
abstract:PURPOSE:To evaluate epithelial healing and visual outcome after laser-assisted subepithelial keratectomy (LASEK) without alcohol de-epithelialization and to compare this technique to photorefractive keratectomy (PRK) in myopia. METHODS:In a series of 1953 patients undergoing bilateral myopic PRK, an epithelial flap co...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1177/112067210301300802
更新日期:2003-10-01 00:00:00
abstract:PURPOSE:To assess the difference in best-corrected visual acuity (BCVA) at presentation between the first and second eye in patients with bilateral neovascular age-related macular degeneration (AMD). METHODS:We reviewed the charts of all patients who had a clinical examination for neovascular AMD at the University Eye...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000649
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:To assess efficacy and safety of angle-supported phakic intraocular lenses (PIOL) implanted after scleral buckling for retinal detachment. SETTING:Private practice in Siena, Italy. METHODS:Retrospective, noncomparative consecutive case series. Inclusion criteria for retrospective evaluation were previous unco...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700319
更新日期:2007-05-01 00:00:00
abstract:PURPOSE:We aimed to discuss the possible role of developmental embryologic factors in neural crest cells in the aetiology of keratoconus and Fuchs' heterochromic iridocyclitis by presenting this case. CASE REPORT:We diagnosed bilateral keratoconus and unilateral Fuchs' heterochromic iridocyclitis in a 19 year old wome...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100114
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy and safety of fixed-combination brimonidine tartrate 0.2%/timolol 0.5% ophthalmic solution dosed BID and demonstrate non-inferiority to concomitant use of brimonidine tartrate 0.2% BID and timolol 0.5% BID in glaucoma and ocular hypertension patients with intraocular pressure (IOP) unco...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.4076
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:This study aimed to assess details of therapy required to achieve an intraocular pressure (IOP) of ⩽12 mmHg in patients with severe glaucoma of different etiologies. METHODS:Patients with a follow-up of at least 1 year, who fulfilled inclusion criteria were selected, and data analyzed with respect to baseline ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120979903
更新日期:2020-12-08 00:00:00
abstract:PURPOSE:Pterygium is an invasive and highly vascularized growth, thought to arise from activated and proliferating limbal epithelial stem cells. Epidemiologic studies have found the increase of active angiogenic and epithelial growth factors in pterygia, and implicated that these molecules could be involved directly or...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800104
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:To present an unusual case of simultaneous bilateral retinal detachment (RD) following a coronary artery bypass graft in a patient with acute myocardial infarction (AMI). METHODS:A 78-year-old man was first seen for bilateral sudden visual loss after surgical treatment of AMI. The patient underwent ultrasound ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700530
更新日期:2007-09-01 00:00:00
abstract::A 62-year-old female developed pseudophakic bullous keratopathy after cataract surgery and underwent Descemet stripping automated endothelial keratoplasty (DSAEK). Intraoperatively, a white opacified pre-Descemet's layer was noticed after scoring and removal of trypan blue stained Descemet's membrane (DM), and endothe...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120974271
更新日期:2020-11-30 00:00:00
abstract:PURPOSE:To carry out a pilot study comparing the size of various types of metallic intraocular foreign bodies as imaged on computed tomographic (CT) scan to their actual size, and to determine the features of different types of metals on CT scan. METHODS:Metallic foreign bodies of predetermined standardized sizes were...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210901900528
更新日期:2009-09-01 00:00:00
abstract:PURPOSE:To determine the long-term visual outcomes and risk factors for visual loss in children with primary congenital glaucoma (PCG) who underwent angle surgery over a 21-year period. METHODS:This was a retrospective study of patients who underwent trabeculotomy, trabeculectomy, or combined trabeculotomy-trabeculect...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000976
更新日期:2017-11-08 00:00:00
abstract:PURPOSE:To present the results of a retrospective comparative unicentric institutional study of the incidence of postcataract surgery endophthalmitis before and after the introduction of the European Society of Cataract and Refractive Surgeons (ESCRS) protocol in 2007 in our department. METHODS:This study included 15,...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000417
更新日期:2014-07-01 00:00:00
abstract:PURPOSE:To describe a case of multiorganism, drug-resistant keratitis that responded well to corneal crosslinking (CXL) treatment. METHODS:A 52-year-old man presented to our institute with a 2-month ocular history of infectious keratitis in his right eye, on topical antibacterial, antifungal, and antiprotozoan treatme...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000755
更新日期:2016-07-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to compare the outcomes of transepithelial photorefractive keratectomy (Trans-PRK) with femtosecond laser assisted in situ keratomileusis (FS-LASIK) for the correction of low to moderate myopia. METHODS:A retrospective cohort study design was used. The study group included pa...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120980346
更新日期:2020-12-14 00:00:00
abstract:INTRODUCTION::The purpose of the study was to estimate the number of people with diabetes mellitus, the prevalence of diabetes mellitus and the prevalence of blindness and severe visual impairment among people with diabetes mellitus in Hungary based on our recent national representative survey. METHODS::Altogether 105...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究
doi:10.1177/1120672118811738
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:To investigate the systemic associations of central serous chorioretinopathy (CSCR) with help of clinical and biochemical investigations. DESIGN:Case-control study. PARTICIPANTS:Eighty seven CSCR patients (case) and 82 Asian-Indian patients with primary non-traumatic rhegmatogenous retinal detachment (contr...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120975698
更新日期:2020-11-25 00:00:00
abstract:PURPOSE:To evaluate the anatomic success rate, visual acuity (VA) changes, and complications of 23-G vitrectomy without associated scleral procedures for the treatment of primary rhegmatogenous retinal detachment (PRRD). METHODS:Patients diagnosed with PRRD were considered for inclusion. Patients with evidence of pr...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000234
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:To evaluate the effect and safety of fovea-sparing internal limiting membrane (ILM) peeling (FSIP) for myopic traction maculopathy comparing with that of total ILM peeling (TP). METHODS:PubMed, Web of science, Embase, Cochrane, EBSCO and CNKI, published until January 2020, were searched. Postoperative best-cor...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120970111
更新日期:2020-11-03 00:00:00
abstract:PURPOSE:To evaluate the efficacy, safety, and tolerability of Timogel® preservative-free once daily compared to timolol 0.5% ophthalmic solution bid in patients with ocular hypertension (OHT) and patients with primary open-angle glaucoma (POAG). METHODS:A total of 75 patients with OHT and patients with POAG treated wi...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000006
更新日期:2012-01-01 00:00:00
abstract::In myopia patients, Rh and acid phosphatase were typed in two groups: group 1 consisted of 214 patients with low myopia (-6 D or less); group 2 of 124 patients with high myopia (more than -6 D). Statistical analysis of the markers showed a good Hardy-Weinberg equilibrium for both groups. In the Rh system there was a s...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract:PURPOSE:The purpose of this paper is to demonstrate a case of bilateral complete avulsion of the globes following maxillofacial trauma. METHODS:A 23-year-old man with bilateral complete globe avulsion following a maxillofacial trauma. Both globes were luxated out of the orbit and suspended on the skin of the upper lid...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210501500119
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:We evaluate the functional and anatomic outcome after intravitreal ranibizumab treatment in patients with choroidal neovascularization (CNV) related to chronic central serous chorioretinopathy (CSC). METHODS:This is a small case series of 5 eyes with CNV associated with chronic CSC treated with intravitreal in...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000524
更新日期:2010-09-01 00:00:00
abstract:PURPOSE:To examine the nature and frequency of ocular side effects due to systemic target therapy with BRAF and MEK inhibitors as well as immunotherapy with cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed cell death 1 (PD-1) monoclonal antibodies used in the treatment of cutaneous malignant melanoma (CMM). DE...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120930688
更新日期:2020-05-31 00:00:00
abstract:PURPOSE:To evaluate the effect of intracameral Bevacizumab on trabeculectomy success rates. METHODS:A prospective, randomized, interventional clinical trial. Patients with primary open-angle glaucoma were randomly assigned to two groups: trabeculectomy with mitomycin C and trabeculectomy with mitomycin C and intracame...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1177/1120672119874682
更新日期:2020-11-01 00:00:00