Photodynamic therapy with verteporfin in the treatment of exudative idiopathic polypoidal choroidal vasculopathy.

Abstract:

PURPOSE:To determine the safety and efficacy of photodynamic therapy with verteporfin (V-PDT) in the treatment of exudative idiopathic polypoidal choroidal vasculopathy (IPCV) lesions that were not suitable for laser photocoagulation. METHODS:This was a prospective, open label study in two centers involving 30 consecutive patients (31 eyes) diagnosed with exudative IPCV using fluorescein angiography (FA), indocyanine green angiography (ICGA), and optical coherence tomography (OCT). All patients underwent complete ophthalmologic examination including best-corrected visual acuity (VA) measurement, contrast sensitivity (CS) testing, FA, ICGA, and OCT. OCT was used to assess the stage of the polypoidal dilations (active or scarred) and the evolution of the signs associated with exudation. Study patients were treated with V-PDT and followed up at 6 weeks and 3, 6, and 12 months. Re-treatment was applied, at an interval of 3 months, until there was an absence of leakage on FA and hyperfluorescence on ICGA. RESULTS:Thirty eyes (29 patients) completed the 12 months post-treatment visit and were retained for further analysis. The mean number of V-PDT treatments was 2.5 (SD 1.1). At 12 months post-treatment, the mean foveal thickness had significantly (p<0.03) decreased to 224 (SD 104) microm from the baseline 292 (SD 124) microm while the mean VA had significantly (p<0.02) improved to 0.50 (SD O.38) from the baseline 0.38 (SD 0.24). Serous detachment of the macula completely resolved in 83.3% of the eyes while 73.3% of the polypoidal dilations were occluded at 12 months. CONCLUSIONS:The results suggest that V-PDT is effective and relatively safe in treating exudative IPCV.

journal_name

Eur J Ophthalmol

authors

Mauget-Faÿsse M,Quaranta-El Maftouhi M,De La Marnièrre E,Leys A

doi

10.1177/112067210601600506

subject

Has Abstract

pub_date

2006-09-01 00:00:00

pages

695-704

issue

5

eissn

1120-6721

issn

1724-6016

journal_volume

16

pub_type

杂志文章,多中心研究
  • Late onset posttraumatic Propionibacterium acnes endophthalmitis.

    abstract:PURPOSE:To report a case of late onset posttraumatic endophthalmitis secondary to Propionibacterium acnes infection. METHODS:Interventional case report. RESULTS:A 28-year-old man developed endophthalmitis 6 months after a penetrating trauma. The patient underwent pars plana lensectomy and vitrectomy along with inject...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/EJO.2008.3552

    authors: Abu El-Asrar AM,Al-Obeidan SA,Yeboah EA

    更新日期:2004-01-01 00:00:00

  • Acute upward gaze palsy: Not always Parinaud syndrome.

    abstract:INTRODUCTION:Parinaud syndrome, caused by midbrain infarction, usually manifests as an ocular conjugate upgaze palsy. However, this sign should not point out straightforwardly to Parinaud syndrome, as other lesions in the central nervous system could cause it. CASE DESCRIPTION:The case of a 47-year-old woman showing a...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672119855845

    authors: Rossi S,Frisullo G,Iorio R

    更新日期:2020-11-01 00:00:00

  • Transplantation failure due to inadvertent reversal of human donor corneas.

    abstract:PURPOSE:To emphasize and create awareness of the possibility of inadvertently grafting an inverted corneal button and describe 4 cases that showed this phenomenon on human donor corneas during preservation and transportation from an eye bank. METHODS:Three out of 4 tissues showed inadvertent inversion during transport...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000711

    authors: Parekh M,Ruzza A,Elbadawy H,Ferrari S,Salvalaio G,Camposampiero D,Ponzin D

    更新日期:2016-02-15 00:00:00

  • Intravitreal steroid slow-release device replacing repeated intravitreal triamcinolone injections for sympathetic ophthalmia.

    abstract:PURPOSE:To report on the intraocular use of a steroid slow-release device in an attempt to avoid multiple intraocular triamcinolone injections in chronic sympathetic ophthalmia. METHODS:A 47-year-old patient with sympathetic ophthalmia had received 17 intravitreal triamcinolone injections to suppress the uveitis, to i...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210801800531

    authors: Jonas JB,Rensch F

    更新日期:2008-09-01 00:00:00

  • Retinopathy of prematurity: a nationwide survey to evaluate current practices and preferences of ophthalmologists.

    abstract:PURPOSE:To emphasize the demographic and occupational characteristics of ophthalmologists primarily involved in retinopathy of prematurity (ROP) care and to ascertain their practices and preferences. METHODS:A questionnaire was sent to all Turkish ophthalmologists known to be primarily involved in ROP. They were asked...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000272

    authors: Sekeroglu MA,Hekimoglu E,Sekeroglu HT,Arslan U

    更新日期:2013-07-01 00:00:00

  • Aflibercept: A review of its effect on the treatment of exudative age-related macular degeneration.

    abstract::Considerable improvement has been achieved in the way in which exudative age-related macular degeneration is conventionally treated and in the associated visual outcomes and prognosis, thanks to the agents with effects against vascular endothelial growth factor (anti-VEGF). By comparison to earlier treatment approache...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,评审

    doi:10.1177/1120672119832432

    authors: Papadopoulos Z

    更新日期:2019-07-01 00:00:00

  • Alterations in antithrombin III activity and other blood coagulation parameters after retinal detachment surgery.

    abstract:PURPOSE:To evaluate perioperative changes in blood coagulation in patients undergoing retinal detachment surgery. MATERIALS:Prospective study of 56 patients, aged from 19 to 82 (mean +/- S.D. 53 +/- 16.8) years, undergoing retinal detachment surgery (encirclement with scleral buckling) under general anesthesia. Exclud...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210001000408

    authors: Malukiewicz-Wiśniewska G,Kotschy M

    更新日期:2000-10-01 00:00:00

  • Unusual presentation of Retinoblastoma.

    abstract::Most cases of retinoblastoma are diagnosed before the age of 5 years. The cases in older age groups can have variable presentations leading to misdiagnosis and management challenges. We report a case of retinoblastoma in an 8-year-old female who was primarily referred as a case of sympathetic ophthalmia due to a co-in...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120939388

    authors: Narang S,Sindhu M,Jinagal J,Handa U,Kochhar S

    更新日期:2020-07-02 00:00:00

  • Comparison of clinical results between heparin surface modified hydrophilic acrylic and hydrophobic acrylic intraocular lens.

    abstract:PURPOSE:To compare the clinical results of heparin surface modified (HSM) hydrophilic acrylic intraocular lens (IOL) with those of hydrophobic acrylic IOL. METHODS:One hundred patients with cataract were randomized to receive one of acrylic foldable IOLs after phacoemulsification: HSM hydrophilic acrylic IOL (n=50) Bi...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,随机对照试验

    doi:10.1177/112067210801800311

    authors: Kang S,Kim MJ,Park SH,Joo CK

    更新日期:2008-05-01 00:00:00

  • Sealed implantation of foldable intraocular lenses.

    abstract:PURPOSE:To evaluate the safety and efficacy of sealed implantation, a simple technique for implanting foldable intraocular lenses (IOLs). METHODS:This was a retrospective study including consecutive patients who underwent phacoemulsification cataract using the sealed implantation technique. Sealed implantation is a te...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000997

    authors: Nath D,Blumenthal EZ,Sharma M,Mimouni M

    更新日期:2017-08-30 00:00:00

  • Studying the role of 10-2 visual field test in different stages of glaucoma.

    abstract:OBJECTIVE:To assess the role of 10-2 visual field (VF) test in different stages of glaucoma. METHODS:In our prospective comparative study, 24-2 and 10-2 VF tests were done for 115 eyes with different stages of glaucomatous damage or glaucoma suspects. Optical coherence tomography (OCT) was performed in 79 eyes. We com...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672119836904

    authors: Tomairek RH,Aboud SA,Hassan M,Mohamed AH

    更新日期:2020-07-01 00:00:00

  • Unilateral optic atrophy preceding Coats disease in a girl with Parry-Romberg syndrome.

    abstract:PURPOSE:Parry-Romberg syndrome (PRS) is a rare disease of unknown etiology and pathogenesis, characterized by progressive hemifacial atrophy. Diverse ocular manifestations were reported in association with PRS, including enophthalmos, lid retraction, blepharoptosis, restrictive strabismus, ocular motor nerve dysfunctio...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067211002000132

    authors: Nasser O,Greiner K,Amer R

    更新日期:2010-01-01 00:00:00

  • Eye health care in Hungary.

    abstract:PURPOSE:To describe eye health-care services provided by in patient Departments of Ophthalmology in Hungary as of 1998. METHODS:A standardised questionnaire was sent to all Hungarian in-patient ophthalmic departments. The response rate was 100%, and data from six university departments and 56 hospitals with ophthalmic...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210201200310

    authors: Németh J,Molnár F,Kocur I

    更新日期:2002-05-01 00:00:00

  • Non-surgical management of congenital ichthyosis using hyaluronic acid gel injection.

    abstract:AIM:To test if hyaluronic acid gel injection in the upper eyelid achieves correction of congenital cicatricial ectropion and reduction in lagophthalmos, in preparation for intraocular surgery. METHODS:This case reports the long-term outcome of hyaluronic acid gel injection in the upper eyelid for the correction of ect...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672118805622

    authors: Cicinelli MV,Dave TV,Madhuri BK,Tiple S,Naik MN

    更新日期:2020-01-01 00:00:00

  • Long-term visual outcomes of vitrectomy for cystoid macular edema due to nonischemic central retinal vein occlusion.

    abstract:PURPOSE:To report the long-term surgical outcome of vitrectomy for cystoid macular edema due to nonischemic central retinal vein occlusion (CRVO). METHODS:A retrospective chart review of 25 consecutive eyes (25 patients) with cystoid macular edema due to nonischemic CRVO treated with vitrectomy was performed. All pati...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210601600609

    authors: Furukawa M,Kumagai K,Ogino N,Uemura A,Larson E

    更新日期:2006-11-01 00:00:00

  • Achieving low target intraocular pressures in severe glaucoma.

    abstract:PURPOSE:This study aimed to assess details of therapy required to achieve an intraocular pressure (IOP) of ⩽12 mmHg in patients with severe glaucoma of different etiologies. METHODS:Patients with a follow-up of at least 1 year, who fulfilled inclusion criteria were selected, and data analyzed with respect to baseline ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120979903

    authors: Warjri GB,Sidhu T,Kishan A,Behera AK,Shakrawal J,Selvan H,Dada T,Pandey V,Sihota R

    更新日期:2020-12-08 00:00:00

  • Sensitivity and specificity of machine learning classifiers and spectral domain OCT for the diagnosis of glaucoma.

    abstract::Purpose. To investigate the sensitivity and specificity of machine learning classifiers (MLC) and spectral domain optical coherence tomography (SD-OCT) for the diagnosis of glaucoma. Methods. Sixty-two patients with early to moderate glaucomatous visual field damage and 48 healthy individuals were included. All subjec...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000183

    authors: Vidotti VG,Costa VP,Silva FR,Resende GM,Cremasco F,Dias M,Gomi ES

    更新日期:2012-06-15 00:00:00

  • Do children and adolescents with attention deficit hyperactivity disorder have ocular abnormalities?

    abstract:PURPOSE:To investigate visual function and ocular features in children with attention deficit hyperactivity disorder (ADHD). METHODS:Fifty-one children underwent a detailed ophthalmologic evaluation. Thirty-two were diagnosed with ADHD, and 19 children with attention deficit disorder (ADD). The mean age was 9.9±3.1 ye...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/ejo.5000145

    authors: Mezer E,Wygnanski-Jaffe T

    更新日期:2012-11-01 00:00:00

  • Optical coherence tomography angiography in myopic choroidal neovascularization after intravitreal ranibizumab.

    abstract:PURPOSE::To describe the optical coherence tomography angiography characteristics of myopic patients with choroidal neovascularization secondary to pathologic myopia during ranibizumab therapy. METHODS::Nineteen patients were enrolled in this prospective study (13 females, 6 males, mean age 55.25 ± 9.63 years) for a t...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672118785495

    authors: Cennamo G,Amoroso F,Schiemer S,Velotti N,Alfieri M,de Crecchio G

    更新日期:2019-03-01 00:00:00

  • Systemic evaluation of patients with central serous chorioretinopathy: A case-control study.

    abstract:OBJECTIVE:To investigate the systemic associations of central serous chorioretinopathy (CSCR) with help of clinical and biochemical investigations. DESIGN:Case-control study. PARTICIPANTS:Eighty seven CSCR patients (case) and 82 Asian-Indian patients with primary non-traumatic rhegmatogenous retinal detachment (contr...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/1120672120975698

    authors: Kumawat D,Ravi AK,Sahay P,Alam T,Desai A,Kumar A

    更新日期:2020-11-25 00:00:00

  • Transient vitreomacular traction syndrome caused by traumatic incomplete posterior vitreous detachment.

    abstract:PURPOSE:To report transient vitreomacular traction (VMT) syndrome following acute blunt trauma associated with incomplete posterior vitreous detachment. METHODS:The authors present the analysis of 2 eyes of consecutive patients with acute VMT following mild blunt trauma. Both patients reported a sudden decrease in vis...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/EJO.2011.6425

    authors: Lorusso M,Micelli Ferrari L,Leozappa M,Modoni AP,Micelli Ferrari T

    更新日期:2011-09-01 00:00:00

  • Optic nerve alterations in PTEN +/- mice.

    abstract:PURPOSE:To study the morphologic characteristics of the optic nerve (ON) by using an experimental model of knockout mice for the expression of the PTEN gene, mainly involved in cell cycle arrest, apoptosis control, and cell size regulation. METHODS:The eyeballs with the retrobulbar ON attached were obtained from 26-we...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.5301/EJO.2008.4510

    authors: Lopez-Sanchez E,Frances-Muoz E,Menezo JL,Pinazo-Duran MD

    更新日期:2006-05-01 00:00:00

  • Can intravitreal tissue plasminogen activator and SF6 gas facilitate management of macular degeneration with photodynamic therapy?

    abstract:PURPOSE:To describe the safety and efficacy of intravitreal tissue plasminogen activator (tPA) and sulfur hexafluoride (SF6) gas with sequential photodynamic therapy (PDT) in the management of submacular hemorrhage (SMH) associated with macular degeneration (MD). METHODS:Consecutive case series of five patients presen...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210801800415

    authors: Muqit MM,Ghanchi FD

    更新日期:2008-07-01 00:00:00

  • Palbebral anthrax.

    abstract:PURPOSE:Anthrax is a rare infection transmitted to humans from animals or animal products. In cutaneous anthrax it may produce lesions of the eyelids which can lead to cicatricial ectropion. METHODS:We examined three women and five men with anthrax of the eyelids. Intravenous penicillin G was used alone as therapy. R...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210101100212

    authors: Celebi S,Aykan U,Alagöz G,Esmerligil S

    更新日期:2001-04-01 00:00:00

  • A new parameter for assessing the thickness of the retinal nerve fiber layer for glaucoma diagnosis.

    abstract:PURPOSE:To investigate a new method for assessing the thickness of the retinal nerve fiber layer thickness (NFLT) for glaucoma diagnosis, using scanning laser polarimetry. MATERIAL AND METHODS:Thirty eyes of thirty patients with ocular hypertension or glaucoma were examined using a scanning laser polarimeter. NFL T wa...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067219900900204

    authors: Kogure S,Iijima H,Tsukahara S

    更新日期:1999-04-01 00:00:00

  • Evaluation of a recently developed noncontact specular microscope in comparison with conventional pachymetry devices.

    abstract:PURPOSE:The study was conducted to assess the central corneal thickness (CCT) of the healthy cornea with a recently developed noncontact specular microscope (EM-3000; Tomey) and compare the results with those measured with a contact specular microscope and an ultrasound pachymeter. Agreement between measurements taken ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067211002000504

    authors: Módis L Jr,Szalai E,Németh G,Berta A

    更新日期:2010-09-01 00:00:00

  • Dacryo-fornix-rhinostomy with two flaps.

    abstract::The two most frequent sites of obstruction of the lacrimal pathways are under the lacrimal sac, in the ductus lacrimonasalis, and over the lacrimal sac, in the canaliculi. The obstruction of the first type already has a satisfactory solution with the different forms of dacryo-cysto-rhinostomies. Obstruction of the sec...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Murube del Castillo J,Martinez Baradas A,Hernandez King J,Cruz Vilella ME,Bahamon Caycedo M

    更新日期:1992-04-01 00:00:00

  • Escherichia coli endophthalmitis after trans-scleral resection of uveal melanoma.

    abstract:PURPOSE:To report a case of Escherichia coli endophthalmitis after trans-scleral resection of an uveal melanoma. METHODS:A large ciliary body melanoma was treated by trans-scleral resection and full-thickness sclerectomy because of epibulbar tumor extrusion, followed by adjuvant ruthenium plaque therapy. RESULTS:Two ...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:10.1177/112067210201200517

    authors: Balestrazzi A,Blasi MA,Primitivo S,Balestrazzi E

    更新日期:2002-09-01 00:00:00

  • Favorable long-term results of primary pterygium removal by bare sclera extirpation followed by a single 90Strontium application.

    abstract:PURPOSE:To describe and compare long-term (> or = 36 months) effects of patients with 86 primary pterygia treated with bare sclera extirpation (BSE) followed by Beta-RT or by sham irradiation. METHODS:Prospective, multicenter, randomized, double-blind study. After BSE of their pterygium, patients were randomized to ei...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1177/112067210801800301

    authors: Mourits MP,Wyrdeman HK,Jurgenliemk-Schulz IM,Bidlot E

    更新日期:2008-05-01 00:00:00

  • Electroretinographic changes during childhood and adolescence.

    abstract::Electroretinogram (ERG) changes with age have been studied widely, but there is no general agreement about the age at which ERG parameters reach adult values. We studied 296 eyes from 148 healthy subjects, divided into 14 age groups, ranging from 1 week to 21 years. Although most of the maturational changes or ERG tak...

    journal_title:European journal of ophthalmology

    pub_type: 杂志文章

    doi:

    authors: Rodriguez-Saez E,Otero-Costas J,Moreno-Montañes J,Relova JL

    更新日期:1993-01-01 00:00:00