Abstract:
PURPOSE:To determine the safety and efficacy of photodynamic therapy with verteporfin (V-PDT) in the treatment of exudative idiopathic polypoidal choroidal vasculopathy (IPCV) lesions that were not suitable for laser photocoagulation. METHODS:This was a prospective, open label study in two centers involving 30 consecutive patients (31 eyes) diagnosed with exudative IPCV using fluorescein angiography (FA), indocyanine green angiography (ICGA), and optical coherence tomography (OCT). All patients underwent complete ophthalmologic examination including best-corrected visual acuity (VA) measurement, contrast sensitivity (CS) testing, FA, ICGA, and OCT. OCT was used to assess the stage of the polypoidal dilations (active or scarred) and the evolution of the signs associated with exudation. Study patients were treated with V-PDT and followed up at 6 weeks and 3, 6, and 12 months. Re-treatment was applied, at an interval of 3 months, until there was an absence of leakage on FA and hyperfluorescence on ICGA. RESULTS:Thirty eyes (29 patients) completed the 12 months post-treatment visit and were retained for further analysis. The mean number of V-PDT treatments was 2.5 (SD 1.1). At 12 months post-treatment, the mean foveal thickness had significantly (p<0.03) decreased to 224 (SD 104) microm from the baseline 292 (SD 124) microm while the mean VA had significantly (p<0.02) improved to 0.50 (SD O.38) from the baseline 0.38 (SD 0.24). Serous detachment of the macula completely resolved in 83.3% of the eyes while 73.3% of the polypoidal dilations were occluded at 12 months. CONCLUSIONS:The results suggest that V-PDT is effective and relatively safe in treating exudative IPCV.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Mauget-Faÿsse M,Quaranta-El Maftouhi M,De La Marnièrre E,Leys Adoi
10.1177/112067210601600506subject
Has Abstractpub_date
2006-09-01 00:00:00pages
695-704issue
5eissn
1120-6721issn
1724-6016journal_volume
16pub_type
杂志文章,多中心研究abstract:PURPOSE:To report a case of late onset posttraumatic endophthalmitis secondary to Propionibacterium acnes infection. METHODS:Interventional case report. RESULTS:A 28-year-old man developed endophthalmitis 6 months after a penetrating trauma. The patient underwent pars plana lensectomy and vitrectomy along with inject...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.3552
更新日期:2004-01-01 00:00:00
abstract:INTRODUCTION:Parinaud syndrome, caused by midbrain infarction, usually manifests as an ocular conjugate upgaze palsy. However, this sign should not point out straightforwardly to Parinaud syndrome, as other lesions in the central nervous system could cause it. CASE DESCRIPTION:The case of a 47-year-old woman showing a...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119855845
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To emphasize and create awareness of the possibility of inadvertently grafting an inverted corneal button and describe 4 cases that showed this phenomenon on human donor corneas during preservation and transportation from an eye bank. METHODS:Three out of 4 tissues showed inadvertent inversion during transport...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000711
更新日期:2016-02-15 00:00:00
abstract:PURPOSE:To report on the intraocular use of a steroid slow-release device in an attempt to avoid multiple intraocular triamcinolone injections in chronic sympathetic ophthalmia. METHODS:A 47-year-old patient with sympathetic ophthalmia had received 17 intravitreal triamcinolone injections to suppress the uveitis, to i...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800531
更新日期:2008-09-01 00:00:00
abstract:PURPOSE:To emphasize the demographic and occupational characteristics of ophthalmologists primarily involved in retinopathy of prematurity (ROP) care and to ascertain their practices and preferences. METHODS:A questionnaire was sent to all Turkish ophthalmologists known to be primarily involved in ROP. They were asked...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000272
更新日期:2013-07-01 00:00:00
abstract::Considerable improvement has been achieved in the way in which exudative age-related macular degeneration is conventionally treated and in the associated visual outcomes and prognosis, thanks to the agents with effects against vascular endothelial growth factor (anti-VEGF). By comparison to earlier treatment approache...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1177/1120672119832432
更新日期:2019-07-01 00:00:00
abstract:PURPOSE:To evaluate perioperative changes in blood coagulation in patients undergoing retinal detachment surgery. MATERIALS:Prospective study of 56 patients, aged from 19 to 82 (mean +/- S.D. 53 +/- 16.8) years, undergoing retinal detachment surgery (encirclement with scleral buckling) under general anesthesia. Exclud...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210001000408
更新日期:2000-10-01 00:00:00
abstract::Most cases of retinoblastoma are diagnosed before the age of 5 years. The cases in older age groups can have variable presentations leading to misdiagnosis and management challenges. We report a case of retinoblastoma in an 8-year-old female who was primarily referred as a case of sympathetic ophthalmia due to a co-in...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120939388
更新日期:2020-07-02 00:00:00
abstract:PURPOSE:To compare the clinical results of heparin surface modified (HSM) hydrophilic acrylic intraocular lens (IOL) with those of hydrophobic acrylic IOL. METHODS:One hundred patients with cataract were randomized to receive one of acrylic foldable IOLs after phacoemulsification: HSM hydrophilic acrylic IOL (n=50) Bi...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1177/112067210801800311
更新日期:2008-05-01 00:00:00
abstract:PURPOSE:To evaluate the safety and efficacy of sealed implantation, a simple technique for implanting foldable intraocular lenses (IOLs). METHODS:This was a retrospective study including consecutive patients who underwent phacoemulsification cataract using the sealed implantation technique. Sealed implantation is a te...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000997
更新日期:2017-08-30 00:00:00
abstract:OBJECTIVE:To assess the role of 10-2 visual field (VF) test in different stages of glaucoma. METHODS:In our prospective comparative study, 24-2 and 10-2 VF tests were done for 115 eyes with different stages of glaucomatous damage or glaucoma suspects. Optical coherence tomography (OCT) was performed in 79 eyes. We com...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119836904
更新日期:2020-07-01 00:00:00
abstract:PURPOSE:Parry-Romberg syndrome (PRS) is a rare disease of unknown etiology and pathogenesis, characterized by progressive hemifacial atrophy. Diverse ocular manifestations were reported in association with PRS, including enophthalmos, lid retraction, blepharoptosis, restrictive strabismus, ocular motor nerve dysfunctio...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000132
更新日期:2010-01-01 00:00:00
abstract:PURPOSE:To describe eye health-care services provided by in patient Departments of Ophthalmology in Hungary as of 1998. METHODS:A standardised questionnaire was sent to all Hungarian in-patient ophthalmic departments. The response rate was 100%, and data from six university departments and 56 hospitals with ophthalmic...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210201200310
更新日期:2002-05-01 00:00:00
abstract:AIM:To test if hyaluronic acid gel injection in the upper eyelid achieves correction of congenital cicatricial ectropion and reduction in lagophthalmos, in preparation for intraocular surgery. METHODS:This case reports the long-term outcome of hyaluronic acid gel injection in the upper eyelid for the correction of ect...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672118805622
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To report the long-term surgical outcome of vitrectomy for cystoid macular edema due to nonischemic central retinal vein occlusion (CRVO). METHODS:A retrospective chart review of 25 consecutive eyes (25 patients) with cystoid macular edema due to nonischemic CRVO treated with vitrectomy was performed. All pati...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210601600609
更新日期:2006-11-01 00:00:00
abstract:PURPOSE:This study aimed to assess details of therapy required to achieve an intraocular pressure (IOP) of ⩽12 mmHg in patients with severe glaucoma of different etiologies. METHODS:Patients with a follow-up of at least 1 year, who fulfilled inclusion criteria were selected, and data analyzed with respect to baseline ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120979903
更新日期:2020-12-08 00:00:00
abstract::Purpose. To investigate the sensitivity and specificity of machine learning classifiers (MLC) and spectral domain optical coherence tomography (SD-OCT) for the diagnosis of glaucoma. Methods. Sixty-two patients with early to moderate glaucomatous visual field damage and 48 healthy individuals were included. All subjec...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000183
更新日期:2012-06-15 00:00:00
abstract:PURPOSE:To investigate visual function and ocular features in children with attention deficit hyperactivity disorder (ADHD). METHODS:Fifty-one children underwent a detailed ophthalmologic evaluation. Thirty-two were diagnosed with ADHD, and 19 children with attention deficit disorder (ADD). The mean age was 9.9±3.1 ye...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000145
更新日期:2012-11-01 00:00:00
abstract:PURPOSE::To describe the optical coherence tomography angiography characteristics of myopic patients with choroidal neovascularization secondary to pathologic myopia during ranibizumab therapy. METHODS::Nineteen patients were enrolled in this prospective study (13 females, 6 males, mean age 55.25 ± 9.63 years) for a t...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672118785495
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:To investigate the systemic associations of central serous chorioretinopathy (CSCR) with help of clinical and biochemical investigations. DESIGN:Case-control study. PARTICIPANTS:Eighty seven CSCR patients (case) and 82 Asian-Indian patients with primary non-traumatic rhegmatogenous retinal detachment (contr...
journal_title:European journal of ophthalmology
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doi:10.1177/1120672120975698
更新日期:2020-11-25 00:00:00
abstract:PURPOSE:To report transient vitreomacular traction (VMT) syndrome following acute blunt trauma associated with incomplete posterior vitreous detachment. METHODS:The authors present the analysis of 2 eyes of consecutive patients with acute VMT following mild blunt trauma. Both patients reported a sudden decrease in vis...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.6425
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To study the morphologic characteristics of the optic nerve (ON) by using an experimental model of knockout mice for the expression of the PTEN gene, mainly involved in cell cycle arrest, apoptosis control, and cell size regulation. METHODS:The eyeballs with the retrobulbar ON attached were obtained from 26-we...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.4510
更新日期:2006-05-01 00:00:00
abstract:PURPOSE:To describe the safety and efficacy of intravitreal tissue plasminogen activator (tPA) and sulfur hexafluoride (SF6) gas with sequential photodynamic therapy (PDT) in the management of submacular hemorrhage (SMH) associated with macular degeneration (MD). METHODS:Consecutive case series of five patients presen...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800415
更新日期:2008-07-01 00:00:00
abstract:PURPOSE:Anthrax is a rare infection transmitted to humans from animals or animal products. In cutaneous anthrax it may produce lesions of the eyelids which can lead to cicatricial ectropion. METHODS:We examined three women and five men with anthrax of the eyelids. Intravenous penicillin G was used alone as therapy. R...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100212
更新日期:2001-04-01 00:00:00
abstract:PURPOSE:To investigate a new method for assessing the thickness of the retinal nerve fiber layer thickness (NFLT) for glaucoma diagnosis, using scanning laser polarimetry. MATERIAL AND METHODS:Thirty eyes of thirty patients with ocular hypertension or glaucoma were examined using a scanning laser polarimeter. NFL T wa...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067219900900204
更新日期:1999-04-01 00:00:00
abstract:PURPOSE:The study was conducted to assess the central corneal thickness (CCT) of the healthy cornea with a recently developed noncontact specular microscope (EM-3000; Tomey) and compare the results with those measured with a contact specular microscope and an ultrasound pachymeter. Agreement between measurements taken ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000504
更新日期:2010-09-01 00:00:00
abstract::The two most frequent sites of obstruction of the lacrimal pathways are under the lacrimal sac, in the ductus lacrimonasalis, and over the lacrimal sac, in the canaliculi. The obstruction of the first type already has a satisfactory solution with the different forms of dacryo-cysto-rhinostomies. Obstruction of the sec...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract:PURPOSE:To report a case of Escherichia coli endophthalmitis after trans-scleral resection of an uveal melanoma. METHODS:A large ciliary body melanoma was treated by trans-scleral resection and full-thickness sclerectomy because of epibulbar tumor extrusion, followed by adjuvant ruthenium plaque therapy. RESULTS:Two ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2002-09-01 00:00:00
abstract:PURPOSE:To describe and compare long-term (> or = 36 months) effects of patients with 86 primary pterygia treated with bare sclera extirpation (BSE) followed by Beta-RT or by sham irradiation. METHODS:Prospective, multicenter, randomized, double-blind study. After BSE of their pterygium, patients were randomized to ei...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/112067210801800301
更新日期:2008-05-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00