Bilateral primary choroidal melanoma treated with bilateral plaque radiotherapy: a report of three cases.

Abstract:

PURPOSE:To report three cases of bilateral primary choroidal melanoma treated with bilateral plaque radiotherapy. METHODS:Retrospective, single-center case series. RESULTS:Case 1: In 1981, a 50-year-old man was diagnosed with a 5-mm-thick choroidal melanoma in the right eye (OD) and treated with plaque radiotherapy. In 1994, a 6.8-mm-thick choroidal melanoma in the left eye (OS) was treated with plaque radiotherapy. Final visual acuity was light perception OD and 20/20 OS at 24 years follow-up. Case 2: In 1983, a 53-year-old woman was diagnosed with a 3.5-mm-thick choroidal melanoma OS and treated with plaque radiotherapy. In 2001, an enlarging 2.5-mm-thick choroidal melanoma OD was treated with plaque radiotherapy. Final visual acuity was 20/30 OD and 20/20 OS at 22 years follow-up. Case 3: In 2001, a 92-year-old man was diagnosed with a 7.9-mm-thick choroidal melanoma OD treated with plaque radiotherapy. In 2003, an enlarging 2.8-mm-thick juxtapapillary choroidal melanoma was treated with plaque radiotherapy. Final visual acuity was 20/70 OD and 20/60 OS at 2.5 years follow-up. No patient showed ocular melanocytosis. Stable tumor regression was achieved in all six eyes. Metastatic disease did not develop in any case over 16 years of follow-up. CONCLUSIONS:Monitoring of both eyes of patients with uveal melanoma is important for the remote possibility of melanoma in the second eye. In these three patients, plaque radiotherapy allowed for preservation of the globes and some vision.

journal_name

Eur J Ophthalmol

authors

Furuta M,Shields CL,Uysal Y,Shields JA

doi

10.1177/112067210601600619

subject

Has Abstract

pub_date

2006-11-01 00:00:00

pages

879-82

issue

6

eissn

1120-6721

issn

1724-6016

journal_volume

16

pub_type

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