Abstract:
PURPOSE:To describe the safety and efficacy of intravitreal tissue plasminogen activator (tPA) and sulfur hexafluoride (SF6) gas with sequential photodynamic therapy (PDT) in the management of submacular hemorrhage (SMH) associated with macular degeneration (MD). METHODS:Consecutive case series of five patients presenting with acute SMH from neovascular MD between May 2004 and January 2006 in a UK Eye Centre. Duration of visual loss was less than 7 weeks. Treatment involved intravitreal injections of tPA, SF6 gas to achieve pneumatic displacement of SMH, and 24 hours prone posturing. Displacement of SMH was assessed by digital photography, and choroidal neovascularization (CNV) was reclassified using angiography. PDT was applied when indicated within 1 to 12 days postoperatively. RESULTS:Adequate displacement of SMH allowed visualization of CNV within 24 hours in three of five patients. One patient with large SMH of 7 weeks duration had partial displacement of SMH. Three patients were reclassified with classic CNV after tPA-SF6 injection, and successfully underwent PDT. CONCLUSIONS:Intravitreal tPA and SF6 assisted pneumatic displacement of SMH is a safe and effective intervention. This technique facilitates more accurate angiographic classification of CNV. PDT may be sequentially and rapidly applied as early as 1 day after injections. The technique may be offered to patients with neovascular MD presenting with acute SMH.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Muqit MM,Ghanchi FDdoi
10.1177/112067210801800415subject
Has Abstractpub_date
2008-07-01 00:00:00pages
591-4issue
4eissn
1120-6721issn
1724-6016journal_volume
18pub_type
杂志文章abstract:PURPOSE:To evaluate the efficacy of AcrySof SN60WF aspheric intraocular lens (IOL) in decreasing spherical aberration and total higher order aberrations (HOAs) after cataract surgery compared to the spherical SN60AT lens. METHODS:Wavefront analysis was conducted on 28 eyes of 28 patients that underwent un-complicated ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700307
更新日期:2007-05-01 00:00:00
abstract:PURPOSE:The present study compared the expression of brain-derived neurotrophic factor (BDNF) in the lateral geniculate body between form deprivation amblyopia kittens and normal kittens to examine the significance of BDNF in the lateral geniculate body in the pathogenesis of amblyopia. METHODS:Twenty kittens were div...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120953341
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:Various methods have been used for testing peripheral visual field disturbances such as defects caused by drug toxicity. Static threshold perimetry with Humphrey Field Analyzer (HFA) is widely available. The aim of this study was to better define the normal thresholds for peripheral visual field (PVF) sensitivi...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.6299
更新日期:2011-07-01 00:00:00
abstract:PURPOSE:A pilot study was carried out to evaluate the practicality, reliability, and validity of an objective structured clinical examination (OSCE) for assessing the clinical skills and abilities of specialists in ophthalmology. METHODS:Ten unfolded OSCE style, criterion referenced questions were asked to nine candid...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210601600415
更新日期:2006-07-01 00:00:00
abstract:OBJECTIVE:To investigate the systemic associations of central serous chorioretinopathy (CSCR) with help of clinical and biochemical investigations. DESIGN:Case-control study. PARTICIPANTS:Eighty seven CSCR patients (case) and 82 Asian-Indian patients with primary non-traumatic rhegmatogenous retinal detachment (contr...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120975698
更新日期:2020-11-25 00:00:00
abstract::Blood flow in various tissues of the body shows spontaneous variations. The purpose of this study was to analyze variations over time in the blood flow of the optic nerve head. Blood flow was measured by the laser Doppler flowmeter (LDF) in 12 healthy volunteers, and analyzed by spectral Fourier analysis. The LDF tech...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1997-10-01 00:00:00
abstract::Although it is now possible to significantly reduce the incidence of blindness secondary to diabetes mellitus, large numbers of diabetic patients still experience visual loss due to retinal complications of the disease. This implies that protocols for the diagnosis and treatment of diabetic retinopathy used in the var...
journal_title:European journal of ophthalmology
pub_type: 社论
doi:10.1177/112067219900900302
更新日期:1999-07-01 00:00:00
abstract:PURPOSE:To analyze the anatomic and functional consequences of wine-cork injury to the eye in relation to the patient's age and the type of cork and wine. METHODS:We retrospectively studied 13 patients, six women and seven men, presenting to our department with bottle-cork injury to the eye between January 1999 and Ju...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210301300308
更新日期:2003-04-01 00:00:00
abstract:PURPOSE:To report a case of extreme corneal flattening after initially uneventful Descemet stripping endothelial keratoplasty (DSEK). METHODS:A 76-year-old man underwent uneventful DSEK for pseudophakic bullous keratopathy (PBK) in his left eye. Postoperative evaluations were performed using anterior segment optical c...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000658
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:To investigate localized retinal dysfunction in hypertensive patients using multifocal electroretinogram (mfERG) and to assess its sensitivity as an early predictor for the development of retinopathy in hypertensive patients. METHODS:Ninety-eight eyes were included in this case-control study. Twenty-eight eyes...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120934750
更新日期:2020-06-12 00:00:00
abstract:OBJECTIVE OF THE STUDY:Inborn lens opacity is the most frequent cause of childhood blindness. In this study, we aimed to define the presumed genetic cause of a congenital cataract present in a Mauritanian family over the last nine generations. METHODS:A family history of the disease and eye examination were carried ou...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672118804757
更新日期:2019-11-01 00:00:00
abstract:PURPOSE::To evaluate the predictive value of magnetic resonance imaging in retinoblastoma for the likelihood of high-risk pathologic features. METHODS::A retrospective study of 64 eyes enucleated from 60 retinoblastoma patients. Contrast-enhanced magnetic resonance imaging was performed before enucleation. Main outcom...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672118781200
更新日期:2019-03-01 00:00:00
abstract:PURPOSE:To describe the detailed surgical technique used for harvesting and transplantation of autologous nasal mucosa grafts for ocular surface reconstruction, to evaluate the clinical results and utility of autologous nasal mucosa grafts in ocular surface diseases. METHODS:Autologous nasal mucosa was harvested from ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.6336
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To describe and compare long-term (> or = 36 months) effects of patients with 86 primary pterygia treated with bare sclera extirpation (BSE) followed by Beta-RT or by sham irradiation. METHODS:Prospective, multicenter, randomized, double-blind study. After BSE of their pterygium, patients were randomized to ei...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/112067210801800301
更新日期:2008-05-01 00:00:00
abstract:PURPOSE:To evaluate the changes in retinal nerve fiber layer thickness (RNFLT), ganglion cell layer thickness (GCLT), retinal thickness (RT), and subfoveal choroidal thickness (SFCT) in eyes that received pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling for idiopathic macular hole (IMH) and to ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000851
更新日期:2017-05-11 00:00:00
abstract::Purpose. To investigate the sensitivity and specificity of machine learning classifiers (MLC) and spectral domain optical coherence tomography (SD-OCT) for the diagnosis of glaucoma. Methods. Sixty-two patients with early to moderate glaucomatous visual field damage and 48 healthy individuals were included. All subjec...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000183
更新日期:2012-06-15 00:00:00
abstract:PURPOSE:Leber hereditary optic neuropathy (LHON) is recognized as the most common cause of isolated blindness in young men. The current study was designed to test whether LHON as a mitochondrial disease is associated with vascular functional alterations characterized by aortic elastic properties during echocardiography...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800225
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:To study the morphologic characteristics of the optic nerve (ON) by using an experimental model of knockout mice for the expression of the P27(Kip1) gene, mainly involved in cell cycle arrest, apoptosis control, and retinoblastoma protein phosphorylation. METHODS:Eyeballs with the retrobulbar ON attached were ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700317
更新日期:2007-05-01 00:00:00
abstract:PURPOSE:To report a case of a combined branch retinal artery and vein occlusion in a patient with hepatitis C treated with interferon and ribavirin. METHODS:A 29-year-old man with a 1-week history of sudden visual field defect and decrease of central visual acuity was examined. RESULTS:Ophthalmoscopy and fluorescein ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.4623
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To evaluate the role of postoperative prone posturing for a single night in the outcome of trans pars plana vitrectomy (TPPV) with internal limiting membrane (ILM) peel and 20% perfluoroethane (C2F6) internal tamponade for idiopathic macular hole. METHODS:This prospective trial enrolled 14 eyes in 14 consecuti...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000039
更新日期:2012-05-01 00:00:00
abstract:SIGNIFICANCE:Susac's syndrome is a rare retinocochleocerebral immune-mediated endotheliopathy and clinically manifests as a pathognomonic triad of encephalopathy, hearing loss, and branch retinal artery occlusion. This triad is rarely present at symptom onset, thus, it is often initially misdiagnosed. To date, Susac's ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120924545
更新日期:2020-05-07 00:00:00
abstract:PURPOSE:To examine whether vitrectomy combined with retinal photocoagulation reduces the vitreous level of vascular endothelial growth factor (VEGF) in patients with macular edema associated with retinal vein occlusion (RVO). METHODS:The authors measured VEGF levels in vitreous samples from four eyes of four patients ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800628
更新日期:2008-11-01 00:00:00
abstract:PURPOSE:To evaluate the efficiency and safety of refractive lens exchange for the correction of high myopia. METHODS:We made a prospective study of the results of refractive lens exchange in 72 eyes that had undergone this surgical procedure between January 1996 and January 2001. Lens extraction by phacoemulsification...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210201200507
更新日期:2002-09-01 00:00:00
abstract:AIM:To review published literature concerning cataract surgery and dry eye disease (DED). METHODS:A search was undertaken using the following: PubMed (all years), Web of Science (all years), Ovid MEDLINE(R) (1946 to 12 December 2019), Ovid MEDLINE(R) Daily Update 10 December 2019, MEDLINE and MEDLINE non-indexed items...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
doi:10.1177/1120672120929958
更新日期:2020-09-01 00:00:00
abstract:PURPOSE:To report on whole body positron emission tomography/computed tomography (PET/CT) screening for metastasis at diagnosis of primary uveal melanoma. METHODS:Since August 2003, 333 consecutive patients were diagnosed with uveal melanoma and underwent whole body screening for metastatic disease with PET/CT along w...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000049
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To investigate whether topical nonsteroidal antiinflammatory drugs (NSAIDs) are useful, in the absence of concomitant corticosteroid therapy, in limiting postoperative inflammation after uncomplicated cataract surgery. METHODS:A total of 328 patients were enrolled in a prospective, randomized, double-masked, p...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:The aim of this article was to study the lower punctum parameters in patients with acquired punctal stenosis using spectral-domain anterior segment optical coherence tomography. SUBJECTS/METHODS:This was a prospective nonrandomized study that included two groups. Group 1 was composed of 32 puncta...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119871396
更新日期:2019-09-06 00:00:00
abstract:PURPOSE:To report the laboratory findings, management strategies, and visual outcomes of culture-proven exogenous fungal endophthalmitis in North China. METHODS:The microbiological and treatment records of patients with culture-positive exogenous fungal endophthalmitis who visited the Affiliated Hospital of Qingdao Un...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119833896
更新日期:2020-05-01 00:00:00
abstract:PURPOSE:To describe the morphologic alterations in ultrasound biomicroscopy (UBM) present in peripheral vitreoretinal toxocariasis. METHODS:An observational prospective study of case series. Fifteen eyes of 15 patients with clinical and laboratory diagnosis of peripheral vitreoretinal toxocariasis were enrolled. The p...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210401400208
更新日期:2004-03-01 00:00:00
abstract:PURPOSE:Twenty-two people with a history of grass pollen allergic conjunctivitis were enrolled outside the pollen season in this study to compare the efficacy of 0.05% mequitazine eyedrops with topical 2% disodium cromoglycate. METHODS:This randomized, double-blind study compared right and left eyes. Subjects received...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1177/112067210001000103
更新日期:2000-01-01 00:00:00