Abstract:
PURPOSE:To investigate localized retinal dysfunction in hypertensive patients using multifocal electroretinogram (mfERG) and to assess its sensitivity as an early predictor for the development of retinopathy in hypertensive patients. METHODS:Ninety-eight eyes were included in this case-control study. Twenty-eight eyes of healthy subjects served as a control group (group I). Seventy eyes belonged to patients with systemic hypertension assigned into two groups; group II including 39 eyes of hypertensive patients with normal fundus and group III including 31 eyes of patients with signs of hypertensive retinopathy. All participants were subjected to complete ophthalmic and electrophysiological examination using mfERG. N1 and P1 wave amplitudes and implicit times from the central hexagon and four concentric rings across the visual field were analyzed. RESULTS:mfERG amplitudes were significantly reduced in hypertensive group with retinopathy than in controls. N1 amplitude was significantly reduced in the most eccentric ring in eyes of hypertensive patients with normal fundus. CONCLUSION:mfERG is a sensitive objective tool for assessment of retinal dysfunction in hypertensive patients. mfERG amplitude is a promising predictor for early development of retinopathy in systemic hypertension.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Farouk AA,ElHadidy R,Attia Abd ElSalam E,Zedan R,Azmy Rdoi
10.1177/1120672120934750subject
Has Abstractpub_date
2020-06-12 00:00:00pages
1120672120934750eissn
1120-6721issn
1724-6016pub_type
杂志文章abstract::Ocular injuries are a frequent cause of monocular blindness and cause disfigurement and discomfort. We developed a measure of severity for eye injuries using a multi-attribute utility (MAU) model. The severity index scoring was applied to eye injuries that presented at hospitals in Wisconsin, U.S.A. The resulting dist...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
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journal_title:European journal of ophthalmology
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