Abstract：
PURPOSE:Leber hereditary optic neuropathy (LHON) is recognized as the most common cause of isolated blindness in young men. The current study was designed to test whether LHON as a mitochondrial disease is associated with vascular functional alterations characterized by aortic elastic properties during echocardiography. METHODS:A total of 19 patients with typical features of LHON aged 42+/-13 years (10 males) were included. Their results were compared to 19 age- and gender-matched healthy controls. Aortic stiffness index was calculated from the echocardiographically derived aortic diameters and the clinical blood pressure data. RESULTS:In this patient population, the point mutation was present in 3460G>A position in five cases, in 11778G>A position in five cases, and in 14484T>C position in nine patients. Diastolic aortic diameter (26.0+/-2.5 mm vs 28.4+/-4.1 mm, p<0.05) and aortic stiffness index (5.1+/-2.6 vs 12.0+/-7.9, p<0.05) were significantly increased in LHON patients compared to controls. CONCLUSIONS:Aortic stiffness can be increased in LHON disease, but further studies are warranted to confirm these findings in a larger LHON patient population with a more reliable method focusing on the pathophysiologic background.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Nemes A,De Coo IF,Spruijt L,Smeets HJ,Chinnery PF,Soliman OI,Geleijnse ML,Ten Cate FJdoi
10.1177/112067210801800225subject
Has Abstractpub_date
2008-03-01 00:00:00pages
309-12issue
2eissn
1120-6721issn
1724-6016journal_volume
18pub_type
杂志文章abstract：PURPOSE:To describe a case of sympathetic ophthalmia (SO) associated with ocular and cerebral vasculitis. METHODS:The authors report a 38-year-old woman who presented with bilateral uveitis 7 years after a penetrating trauma to the right eye. Ocular examination included fundus fluorescein and indocyanine green angiogr...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210301300614
更新日期：2003-07-01 00:00:00
abstract：AIM:To test if hyaluronic acid gel injection in the upper eyelid achieves correction of congenital cicatricial ectropion and reduction in lagophthalmos, in preparation for intraocular surgery. METHODS:This case reports the long-term outcome of hyaluronic acid gel injection in the upper eyelid for the correction of ect...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672118805622
更新日期：2020-01-01 00:00:00
abstract：PURPOSE:The imaging quality provided by a piggyback integrated by a monofocal intraocular lens (IOL) + a bifocal IOL of zero power and +3.75 diopters of addition is compared with the optics quality of a simple multifocal IOL of the same power and addition. METHODS:The imaging quality was evaluated by determining the m...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067211002000109
更新日期：2010-01-01 00:00:00
abstract：INTRODUCTION:To identify novel velocity waveform parameters of the ophthalmic artery and central retinal artery by computer-aided image processing of Doppler ultrasonography measurements, and to evaluate correlations between the waveform parameters and different demographics and disease severity of open-angle glaucoma ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672119848259
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:To determine the visual outcome, intraocular lens (IOL) stability and posterior capsule opacification (PCO) rate of a hydrophobic acrylic intraocular lens. SETTING:Vienna Institute for Research in Ocular Surgery, Hanusch Hospital, Vienna, Austria. DESIGN:This double-masked randomised study included patients w...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120960591
更新日期：2020-09-29 00:00:00
abstract：PURPOSE:To compare the clinical results of heparin surface modified (HSM) hydrophilic acrylic intraocular lens (IOL) with those of hydrophobic acrylic IOL. METHODS:One hundred patients with cataract were randomized to receive one of acrylic foldable IOLs after phacoemulsification: HSM hydrophilic acrylic IOL (n=50) Bi...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,随机对照试验
doi：10.1177/112067210801800311
更新日期：2008-05-01 00:00:00
abstract：PURPOSE:To report the visual and refractive outcomes of sequential intracorneal ring segment (ICRS) and toric phakic intraocular lens (IOL) insertion for visual rehabilitation in keratoconus. METHODS:A retrospective interventional cohort study was performed through the Corneoplastics unit and Eye Bank, Queen Victoria ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120969600
更新日期：2020-11-02 00:00:00
abstract：PURPOSE:To report a case of acute frosted branch angiitis associated with acquired toxoplasmosis in which a late peripheral chorioretinal scar developed. RESULTS:A 32-year-old man without systemic symptoms presented with sudden visual loss in his left eye. Examination demonstrated frosted branch angiitis without necro...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067210301300812
更新日期：2003-10-01 00:00:00
abstract：PURPOSE:To describe the demographics and clinical characteristics of work-related open-globe injuries (OGIs) at a level I trauma center over a 10-year period. METHODS:Retrospective series. RESULTS:A total of 183 eyes with work-related OGIs were identified. The majority of injuries occurred in men (96.7%). The anatomi...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000209
更新日期：2013-03-01 00:00:00
abstract：PURPOSE:To evaluate the short-term efficacy and safety of intravitreal bevacizumab in myopic choroidal neovascularization (mCNV). METHODS:In this noncomparative, consecutive, interventional case series, 12 eyes of 11 patients with mCNV without any previous treatment were included. Patients received intravitreal bevaci...
journal_title：European journal of ophthalmology
pub_type： 临床试验,杂志文章
doi：10.1177/112067210701700422
更新日期：2007-07-01 00:00:00
abstract：PURPOSE:To report management of diplopia with botulinum toxin injection in traumatic multiple ocular motor cranial neuropathies. METHODS:Alternate prism and cover measurement of deviation in different positions of gaze, examination of ductions, field of binocular single vision, and complete ocular anterior and poste...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000202
更新日期：2012-11-01 00:00:00
abstract：PURPOSE:To describe the long-term clinical course of patients with low-pressure glaucoma (LPG) and to assess the risk factors for disease progression. METHODS:The Wills Eye Glaucoma Research Center retrospectively reviewed the charts of LPG patients with documented follow-up of >8 years between 2000 and 2013. Medical ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000624
更新日期：2015-11-01 00:00:00
abstract：OBJECTIVE:To investigate the systemic associations of central serous chorioretinopathy (CSCR) with help of clinical and biochemical investigations. DESIGN:Case-control study. PARTICIPANTS:Eighty seven CSCR patients (case) and 82 Asian-Indian patients with primary non-traumatic rhegmatogenous retinal detachment (contr...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120975698
更新日期：2020-11-25 00:00:00
abstract：PURPOSE:To evaluate accuracy and inter-rater reliability of RetCam fundus images and digital camera fluorangioscopic images in acute retinopathy of prematurity (ROP) by comparing diagnoses given by trainee ophthalmologists with those provided by expert ophthalmologists. METHODS:This is a multicenter retrospective ob...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,多中心研究
doi：10.5301/ejo.5000319
更新日期：2013-11-01 00:00:00
abstract：PURPOSE:To report a case of Candida albicans keratitis after Descemet stripping with automated endothelial keratoplasty (DSAEK) due to fungal contamination of the donor cornea. METHODS:Case report. RESULTS:A 73-year-old woman underwent phacoemulsification with intraocular lens (IOL) implantation and DSAEK with 1 week...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000499
更新日期：2014-11-01 00:00:00
abstract：PURPOSE:To compare the outcomes after switching between bevacizumab and ranibizumab therapy due to poor treatment effect in neovascular age-related macular degeneration (AMD). METHODS:This is a retrospective review of patients with neovascular AMD with first treatment using intravitreal bevacizumab (group 1) or ranibi...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000480
更新日期：2015-01-01 00:00:00
abstract：:Age-related macular degeneration is a condition (a) characterized by accumulation of membranous debris on both sides of the retinal pigment epithelium (RPE) basement membrane. Clinical manifestations of drusen, atrophy of the RPE/choriocapillaris, RPE detachment, and choroidal new vessel (CNV) formation occur after ag...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,评审
doi：
更新日期：1998-10-01 00:00:00
abstract：UNLABELLED:PURPOSE. To report a case of scleral dislocation mimicking glaucoma progression. METHODS:Interventional case report. RESULTS:A 71-year-old man was referred for glaucoma surgery in his right eye because of perimetry defect progression and uncontrolled intraocular pressure despite maximal medical therapy. A ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000165
更新日期：2013-03-01 00:00:00
abstract：PURPOSE:To prospectively compare the clinical results of two cataract surgery procedures through a 4.0-mm incision, differing only in the wound location (superior or lateral). METHODS:168 eyes with cataract were randomly assigned to either procedure. Except for incision location, surgical methods were identical. Uncor...
journal_title：European journal of ophthalmology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1996-10-01 00:00:00
abstract：PURPOSE:Timely screening of premature babies is an important initial step in the management of retinopathy of prematurity (ROP) as earlier treatment results in improved visual prognosis. Screening criteria for ROP currently recommended by the American Academy of Pediatrics may not be applicable in developing countries....
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067211002000417
更新日期：2010-07-01 00:00:00
abstract：PURPOSE:To evaluate the changes of corneal biomechanics and the intraocular pressure during pregnancy in a Chinese healthy female population. METHODS:A total of 222 unrelated Chinese females were recruited: 52 non-pregnant, 15 pregnant in the first trimester, 68 pregnant in the second trimester, and 87 pregnant in the...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120902034
更新日期：2020-01-27 00:00:00
abstract：PURPOSE:To evaluate the use of the resorbable polylactic acid polymer implants (Resorb X) in the management of orbital floor blow-out fractures as regards safety, cosmetic, and functional results. METHODS:In a prospective, interventional case series, 22 patients with traumatic blow-out floor fractures underwent lower ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120928005
更新日期：2020-05-31 00:00:00
abstract：PURPOSE:The study was conducted to assess the central corneal thickness (CCT) of the healthy cornea with a recently developed noncontact specular microscope (EM-3000; Tomey) and compare the results with those measured with a contact specular microscope and an ultrasound pachymeter. Agreement between measurements taken ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067211002000504
更新日期：2010-09-01 00:00:00
abstract：PURPOSE:To analyze the relationship between retinal nerve fiber layer thickness (RNFLT) and intraocular pressure (IOP) variation in glaucoma suspects (GS) and patients with primary open-angle glaucoma (POAG). METHODS:Thirty-one GS and 34 POAG patients underwent ophthalmologic examination and 24-h IOP measurements. GS ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/1120672120957584
更新日期：2020-09-09 00:00:00
abstract：AIM:To review published literature concerning cataract surgery and dry eye disease (DED). METHODS:A search was undertaken using the following: PubMed (all years), Web of Science (all years), Ovid MEDLINE(R) (1946 to 12 December 2019), Ovid MEDLINE(R) Daily Update 10 December 2019, MEDLINE and MEDLINE non-indexed items...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,评审
doi：10.1177/1120672120929958
更新日期：2020-09-01 00:00:00
abstract：PURPOSE:To report a case of presumed bilateral acute retinal necrosis with delayed onset caused by herpes simplex virus type 2, medical treatment, and surgical approach. METHODS:Retrospective, interventional case described in a 51-year-old patient who complained of unilateral blurred vision with history of nonoperated...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000596
更新日期：2015-07-30 00:00:00
abstract：PURPOSE:To study the correlation between final visual acuity after successful anatomic macular hole repair and features on spectral domain optical coherence tomography (SD-OCT). METHODS:Retrospective review of charts of patients who underwent macular hole surgery. Data collection included pre- and postoperative best-c...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.1177/112067211002000306
更新日期：2010-05-01 00:00:00
abstract：PURPOSE:To describe a new technique for remnant removal in cases of posterior capsular rupture during cataract surgery and Soemmering ring extraction during intraocular lens (IOL) removal. METHODS:An IOL injector, inserted into the anterior chamber, provides a new exit for residual lens fragments. Passive fluid flow, ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000962
更新日期：2017-06-26 00:00:00
abstract：:Electroretinogram (ERG) changes with age have been studied widely, but there is no general agreement about the age at which ERG parameters reach adult values. We studied 296 eyes from 148 healthy subjects, divided into 14 age groups, ranging from 1 week to 21 years. Although most of the maturational changes or ERG tak...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
abstract：PURPOSE:To report on phototherapeutic keratectomy (PTK) in myopic patients who developed spontaneous recurrent corneal erosions (RCE) following IntraLASIK. METHODS:Recurrent corneal erosions developed spontaneously 3-6 months following IntraLASIK in 4 eyes of 4 myopic patients. Diffuse lamellar keratitis (DLK) subsequ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5000097
更新日期：2012-01-01 00:00:00
