Abstract：
PURPOSE:To analyze the relationship between retinal nerve fiber layer thickness (RNFLT) and intraocular pressure (IOP) variation in glaucoma suspects (GS) and patients with primary open-angle glaucoma (POAG). METHODS:Thirty-one GS and 34 POAG patients underwent ophthalmologic examination and 24-h IOP measurements. GS had IOPs ranging from 19 to 24 mmHg and/or suspicious appearance of the optic nerve. POAG patients had reproducible abnormal visual fields. We only included patients who presented with short-term IOP fluctuation >6 mm Hg (∆IOP). Only one eye per patient was included through a randomized process. Peripapillary RNFLT was assessed by spectral-domain optical coherence tomography. We correlated RNFLT with IOP parameters. RESULTS:Mean IOP was similar between GS and POAG groups (15.6 ± 3.47 vs 15.6 ± 2.83 mmHg, p = 0.90) as was IOP peak at 6 AM (21.7 ± 3.85 vs 21.3 ± 3.80 mmHg, p = 0.68). Statistically significant negative correlations were found in POAG group between IOP at 6 AM and RNFLT in global (rs = -0.543; p < 0.001), inferior (rs = -0.540; p < 0.001), superior (rs = -0.405; p = 0.009), and nasal quadrants (rs = -0.561; p < 0.001). Negative correlations were also found between ∆IOP and RNFLT in global (rs = -0.591; p < 0.001), and all other sectors (p < 0.05). In GS IOP at 6 AM correlated only with inferior quadrant (rs = -0.307; p = 0.047). CONCLUSION:IOP at 6 AM and ∆IOP had negative correlations with RNFLT quadrants in POAG. In GS this correlation occurred between IOP at 6 AM and inferior quadrant. These findings may indicate potential risk factors for glaucoma progression.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Cronemberger S,Veloso AW,Veiga C,Scarpelli G,Sasso YC,Merola RVdoi
10.1177/1120672120957584subject
Has Abstractpub_date
2020-09-09 00:00:00pages
1120672120957584eissn
1120-6721issn
1724-6016pub_type
杂志文章abstract：PURPOSE:To describe a case of rubella retinopathy complicated by bilateral choroidal neovascularization (CNV) and late development of large choroidal excavation (LCE). METHODS:A 19-year-old woman with a diagnosis of rubella retinopathy underwent her annual ophthalmologic examination, including visual acuity testing an...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：10.5301/ejo.5001056
更新日期：2018-03-01 00:00:00
abstract：:Retinal ganglion cells (RGCs) undergo programmed cell death (apoptosis) after axonal injury. This cell death is mediated by several mechanisms, including deprivation of neurotrophic factors, alterations in gene expression, and production of reactive oxygen species. However, death of RGCs is delayed after axonal injury...
journal_title：European journal of ophthalmology
pub_type： 杂志文章,评审
doi：
更新日期：1999-01-01 00:00:00
abstract：PURPOSE:We evaluate the functional and anatomic outcome after intravitreal ranibizumab treatment in patients with choroidal neovascularization (CNV) related to chronic central serous chorioretinopathy (CSC). METHODS:This is a small case series of 5 eyes with CNV associated with chronic CSC treated with intravitreal in...
journal_title：European journal of ophthalmology
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doi：10.1177/112067211002000524
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
pub_type： 杂志文章,多中心研究
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abstract：PURPOSE:The study was conducted to assess the central corneal thickness (CCT) of the healthy cornea with a recently developed noncontact specular microscope (EM-3000; Tomey) and compare the results with those measured with a contact specular microscope and an ultrasound pachymeter. Agreement between measurements taken ...
journal_title：European journal of ophthalmology
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abstract：PURPOSE:To evaluate the efficacy, safety, and tolerability of Timogel® preservative-free once daily compared to timolol 0.5% ophthalmic solution bid in patients with ocular hypertension (OHT) and patients with primary open-angle glaucoma (POAG). METHODS:A total of 75 patients with OHT and patients with POAG treated wi...
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journal_title：European journal of ophthalmology
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更新日期：2004-01-01 00:00:00
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更新日期：2017-05-11 00:00:00
abstract：:not available. ...
journal_title：European journal of ophthalmology
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doi：10.5301/EJO.2008.1196
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更新日期：2002-07-01 00:00:00
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journal_title：European journal of ophthalmology
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：:Two cases of idiopathic sclerochoroidal calcification are reported with follow-up of two and ten years. In addition we have reviewed 102 cases of choroidal osteoma, including six misleading case reports which actually described idiopathic sclerochoroidal calcification and not choroidal osteoma. Clinical manifestation ...
journal_title：European journal of ophthalmology
pub_type： 杂志文章
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更新日期：1991-10-01 00:00:00
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pub_type： 临床试验,杂志文章
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journal_title：European journal of ophthalmology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：
更新日期：2004-11-01 00:00:00
