Abstract：
PURPOSE::To describe the optical coherence tomography angiography characteristics of myopic patients with choroidal neovascularization secondary to pathologic myopia during ranibizumab therapy. METHODS::Nineteen patients were enrolled in this prospective study (13 females, 6 males, mean age 55.25 ± 9.63 years) for a total of 20 eyes examined (14 right eyes, 6 left eyes). Images were analyzed independently by two examiners. RESULTS::Mean follow-up was 5.75 ± 1.88 months, with a mean intravitreal injections of 1.90 ± 0.44. Mean best-corrected visual acuity at baseline was 0.39 ± 0.18 logMAR versus 0.26 ± 0.16 logMAR 6 months after treatment. The neovascular area (Z = -2.091, p = 0.037) was significantly reduced after treatment, whereas vessel density was not (Z = -1.848, p = 0.065). Moreover, the best-corrected visual acuity was increased (Z = -3.055, p = 0.002). Neovascular area was significantly correlated with best-corrected visual acuity, at both baseline and follow-up (p < 0.05). CONCLUSION::Our data suggest that optical coherence tomography angiography is a reproducible non-invasive examination with which to monitor changes in the neovascular area in patients with pathologic myopia treated with ranibizumab.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Cennamo G,Amoroso F,Schiemer S,Velotti N,Alfieri M,de Crecchio Gdoi
10.1177/1120672118785495subject
Has Abstractpub_date
2019-03-01 00:00:00pages
239-243issue
2eissn
1120-6721issn
1724-6016journal_volume
29pub_type
杂志文章abstract：:Most cases of retinoblastoma are diagnosed before the age of 5 years. The cases in older age groups can have variable presentations leading to misdiagnosis and management challenges. We report a case of retinoblastoma in an 8-year-old female who was primarily referred as a case of sympathetic ophthalmia due to a co-in...
journal_title：European journal of ophthalmology
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abstract：PURPOSE:To compare demographic and clinical data, systemic disease association, visual prognosis, and complications found in childhood and adult onset of intermediate uveitis (IU). METHODS:Retrospective cohort study of 287 patients with IU: 122 (42.5%) children at onset (<16 years), 165 (57.5%) adults. The data were e...
journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
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journal_title：European journal of ophthalmology
pub_type： 杂志文章,评审
doi：
更新日期：1998-10-01 00:00:00
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