Abstract:
PURPOSE:To describe our clinical experience with the efficacy and safety of micropulse transscleral cyclophotocoagulation as a treatment for glaucoma. METHODS:In this retrospective case series, we reviewed the charts of 95 consecutive patients with various glaucoma subtypes who underwent micropulse transscleral cyclophotocoagulation. Patients were offered micropulse transscleral cyclophotocoagulation if they had perimetric glaucoma refractory to intraocular pressure-lowering topical medications and who were poor candidates for traditional filtering surgery. Eligible patients were treated with the Micropulse P3 device (IQ 810 Laser Systems; Iridex, Mountain View, CA, USA) at 2.0-2.5 W for a duration of 90 s per hemisphere at a 31.3% duty cycle. If a retreatment was needed, the power was increased to up to 3.0 W with other parameters remaining the same. Patients were considered successfully treated if their intraocular pressure was lowered by at least 20% compared to their baseline. The main outcome measure was post-operative intraocular pressure; secondary outcome measures included the number of adverse events and complications that occurred with treatment. RESULTS:The glaucoma subtypes treated included primary open-angle glaucoma (n = 51), exfoliation glaucoma (n = 24), chronic angle-closure glaucoma (n = 15), and congenital/juvenile glaucoma (n = 5). The mean pre-operative intraocular pressure was 25.1 ± 5.3 mm Hg and the mean post-operative intraocular pressure at 12 months was 17.5 ± 5.1 mm Hg (p = 0.004). The mean number of intraocular pressure-lowering medications used preoperatively was 3.0 ± 1.1; the mean number of medications used at the 12-month post-operative visit was 1.4 ± 1.0 (p = 0.03). Success with one treatment was achieved in 73 (76.8%) of patients. With multiple treatments, all patients had significant intraocular pressure-lowering compared to baseline. The maximum number of treatments received by any single patient was 5. There were no instances of prolonged intraocular inflammation or long-term hypotony. CONCLUSION:Micropulse transscleral cyclophotocoagulation appears to be a safe and efficacious treatment for glaucoma. Given its improved safety profile compared to continuous-wave transscleral cyclophotocoagulation, it deserves consideration as a primary procedure.
journal_name
Eur J Ophthalmoljournal_title
European journal of ophthalmologyauthors
Nguyen AT,Maslin J,Noecker RJdoi
10.1177/1120672119839303subject
Has Abstractpub_date
2020-07-01 00:00:00pages
700-705issue
4eissn
1120-6721issn
1724-6016journal_volume
30pub_type
杂志文章abstract:PURPOSE:Retinopathy is the major cause of ocular morbidity in patients with diabetes mellitus. Chronic hyperglycemia spares no organ and can affect the morphology and function of the various corneal layers, compromising its transparency. This study was conducted to associate the status of corneal endothelium to diabete...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210901900307
更新日期:2009-05-01 00:00:00
abstract::Purpose. To record the information used in order to make a retreatment decision in patients with exudative age-related macular degeneration (AMD) and to assess if an optical coherence tomography (OCT)-only follow-up clinic would suffice. Methods. Two hundred patients under treatment with intravitreal anti-vascular end...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000190
更新日期:2012-08-06 00:00:00
abstract:PURPOSE:The effect of elevated blood glucose level on the myogenic response of human retinal arterioles to acute increases in blood pressure is investigated. METHODS:The vascular response to raised blood pressure (Bayliss effect) was measured in 12 healthy volunteers by use of the retinal vessel analyzer (RVA). For a ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210501500109
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:Leber hereditary optic neuropathy (LHON) is recognized as the most common cause of isolated blindness in young men. The current study was designed to test whether LHON as a mitochondrial disease is associated with vascular functional alterations characterized by aortic elastic properties during echocardiography...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210801800225
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:To prospectively compare the clinical results of two cataract surgery procedures through a 4.0-mm incision, differing only in the wound location (superior or lateral). METHODS:168 eyes with cataract were randomly assigned to either procedure. Except for incision location, surgical methods were identical. Uncor...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1996-10-01 00:00:00
abstract:OBJECTIVE:Riboflavin UVA (collagen crosslinking [CXL]) treatment for keratoconus is a method for stabilizing or improving corneal properties. Our aim was to evaluate changes in corneal topography indices after CXL. METHODS:A total of 38 eyes of 25 patients (mean age 29.36 ± 9.7 years) were treated with CXL technique...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000249
更新日期:2013-09-01 00:00:00
abstract:PURPOSE:To analyze and compare the high performance liquid chromatography (HPLC) runs of tear proteins from diabetic (DIDRY) and non-diabetic (DRY) dry-eye patients, and healthy subjects (CTRL). The patterns were analyzed using multivariate statistical methods. METHODS:Tears (total 56 eyes: CTRL: n=16, DIDRY: n=21, an...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210101100105
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:To report the results of corneal collagen crosslinking (CXL) in a patient with corneal ectasia developed after excimer laser-assisted lamellar keratoplasty for keratoconus and a secondary photorefractive keratectomy (PRK) for residual refractive error. METHODS:A 33-year-old woman, who had originally been treat...
journal_title:European journal of ophthalmology
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doi:10.5301/ejo.5000019
更新日期:2012-03-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000442
更新日期:2014-07-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of the ISNT rule in normal eyes of Koreans. METHODS:We retrospectively reviewed medical records of 890 subjects with fundus photographs and evaluated the presence of the cup and ISNT rule satisfaction. If the ISNT rule was violated, the quadrants in which the neuroretinal rim was thinn...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672119876824
更新日期:2021-01-01 00:00:00
abstract:PURPOSE:To assess the frequency of pseudoexfoliation syndrome (PEX) and evaluate its association with specific ocular diseases in patients attending the Department of Ophthalmology at Gaziosmanpasa University Hospital. METHODS:A prospective study was conducted at the Gaziosmanpasa University Hospital between December ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067211002000621
更新日期:2010-11-01 00:00:00
abstract::This prospective study of 123 patients undergoing cataract extraction determined the preoperative and surgical factors predisposing to an exaggerated postoperative inflammatory response. It is important to identify the patients at increased risk of complications requiring additional prophylaxis or more intensive posto...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of AcrySof SN60WF aspheric intraocular lens (IOL) in decreasing spherical aberration and total higher order aberrations (HOAs) after cataract surgery compared to the spherical SN60AT lens. METHODS:Wavefront analysis was conducted on 28 eyes of 28 patients that underwent un-complicated ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700307
更新日期:2007-05-01 00:00:00
abstract:PURPOSE:To evaluate the effect and safety of fovea-sparing internal limiting membrane (ILM) peeling (FSIP) for myopic traction maculopathy comparing with that of total ILM peeling (TP). METHODS:PubMed, Web of science, Embase, Cochrane, EBSCO and CNKI, published until January 2020, were searched. Postoperative best-cor...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120970111
更新日期:2020-11-03 00:00:00
abstract:PURPOSE:To report on whole body positron emission tomography/computed tomography (PET/CT) screening for metastasis at diagnosis of primary uveal melanoma. METHODS:Since August 2003, 333 consecutive patients were diagnosed with uveal melanoma and underwent whole body screening for metastatic disease with PET/CT along w...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000049
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To evaluate and compare the glaucoma discrimination ability of macula, macular ganglion cell complex (mGCC), and peripapillary nerve fiber layer (ppNFL) thickness in Chinese patients using Fourier-domain optical coherence tomography (FD-OCT). METHODS:A total of 64 normal subjects (N), 47 glaucoma suspects (GS)...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000131
更新日期:2012-11-01 00:00:00
abstract:PURPOSE:To determine the relationship between movements of the posterior and anterior eye segments during arbitrary gaze shifts and to obtain information for monitoring fixation during radiotherapy for ocular diseases. METHODS:We examined eye movements of ten emmetropic volunteers in a 1.5 T magnetic resonance system....
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210301300212
更新日期:2003-03-01 00:00:00
abstract:PURPOSE:The authors report the ophthalmic characteristics of a male proband in a Japanese family with autosomal dominant optic atrophy (DOA) harboring a frameshift mutation in the OPA1 gene. METHODS:Conventional ophthalmologic examinations including static automated perimetry were performed, as well as assessment of t...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700216
更新日期:2007-03-01 00:00:00
abstract:PURPOSE:To study the morphologic characteristics of the optic nerve (ON) by using an experimental model of knockout mice for the expression of the P27(Kip1) gene, mainly involved in cell cycle arrest, apoptosis control, and retinoblastoma protein phosphorylation. METHODS:Eyeballs with the retrobulbar ON attached were ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/112067210701700317
更新日期:2007-05-01 00:00:00
abstract:PURPOSE:To describe and compare long-term (> or = 36 months) effects of patients with 86 primary pterygia treated with bare sclera extirpation (BSE) followed by Beta-RT or by sham irradiation. METHODS:Prospective, multicenter, randomized, double-blind study. After BSE of their pterygium, patients were randomized to ei...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1177/112067210801800301
更新日期:2008-05-01 00:00:00
abstract:PURPOSE:To describe the detailed surgical technique used for harvesting and transplantation of autologous nasal mucosa grafts for ocular surface reconstruction, to evaluate the clinical results and utility of autologous nasal mucosa grafts in ocular surface diseases. METHODS:Autologous nasal mucosa was harvested from ...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2011.6336
更新日期:2011-09-01 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To assess the association between appearance of dissociated optic nerve fiber layer (DONFL) after internal limiting membrane (ILM) peeling and changes in the macular nerve fiber layer (NFL) area by spectral-domain optical coherence tomography (SD-OCT). METHODS:This study included 132 consecutive patients who h...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2018-05-01 00:00:00
abstract:PURPOSE:To evaluate the safety and efficacy of sealed implantation, a simple technique for implanting foldable intraocular lenses (IOLs). METHODS:This was a retrospective study including consecutive patients who underwent phacoemulsification cataract using the sealed implantation technique. Sealed implantation is a te...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/ejo.5000997
更新日期:2017-08-30 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.5301/EJO.2008.3247
更新日期:2005-01-01 00:00:00
abstract::The purpose of this study was to evaluate the hemodynamic changes occurring in the ophthalmic vasculature of eyes with Behçet's disease in a controlled clinical trial. Both eyes of patients with retinal involvement due to Behçet's disease were consecutively evaluated and were established as having mild or severe retin...
journal_title:European journal of ophthalmology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1997-07-01 00:00:00
abstract:INTRODUCTION:Preretinal hemorrhages can be located in subhyaloid or sub-internal limiting membrane (ILM) space. Though optical coherence tomography (OCT) may help to distinguish the exact location of hemorrhage in selected cases, it is often difficult to discern clinically. The purpose is to describe a novel clinical s...
journal_title:European journal of ophthalmology
pub_type: 杂志文章
doi:10.1177/1120672120934958
更新日期:2020-06-22 00:00:00
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journal_title:European journal of ophthalmology
pub_type: 杂志文章
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更新日期:2000-10-01 00:00:00
abstract::Wet age-related macular degeneration is a chronic condition culminating, in most cases, in blindness. The introduction of anti-angiogenic agents in 2006 has represented a major breakthrough in the treatment of the disease, but timely and effective treatment with regular follow-up and monitoring is mandatory to stabili...
journal_title:European journal of ophthalmology
pub_type: 杂志文章,评审
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更新日期:2020-07-01 00:00:00
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journal_title:European journal of ophthalmology
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更新日期:2018-03-01 00:00:00