The effect of clinical severity and eyelid rash on ocular involvement in primary varicella infection.

Abstract:

PURPOSE:To describe ocular manifestations in primary varicella infection and their relationship to systemic severity and the associated eyelid rash. METHODS:One hundred consecutive children with primary varicella were examined prospectively. The cases were classified as mild, moderate, and severe according to the severity of clinical presentation. Excluding the presence of eyelid rash, children with ocular findings were assigned to group 1 (G1), and those without ocular findings were assigned to group 2 (G2). Patients in G1 were also evaluated according to the nature of ocular manifestations and the course of uveitis. RESULTS:Twenty-one percent of patients had ocular involvement (G1) and 79% had no ocular involvement (G2). While chickenpox had a mild course in 85.7% of patients in G1 and 88.6% of patients in G2, all others had a moderate course. None of the children had a severe course. A varicella eyelid rash was present in 28.6% of patients in G1 and 13.9% in G2. Among ocular findings, 38.1% of patients had conjunctivitis, 57.1% had anterior uveitis, and 4.8% had disciform keratouveitis. There was no significant association between severity of chickenpox and severity of ocular involvement (p=0.712). There was also no relationship between eyelid rash and ocular involvement (p=0.787). CONCLUSIONS:There is neither an association between the severity of chickenpox and the severity of ocular involvement nor an association between the presence of a varicella eyelid rash and the development of uveitis. As the prognosis regarding sequelae of ocular involvement in varicella infection is good, only those patients with ocular signs and symptoms need be referred by pediatricians for an ophthalmologic examination.

journal_name

Eur J Ophthalmol

authors

Sungur G,Hazirolan D,Duran S,Satana B,Arikan I,Duman S

subject

Has Abstract

pub_date

2009-11-01 00:00:00

pages

905-8

issue

6

eissn

1120-6721

issn

1724-6016

pii

DE206FE3-1F87-43AC-A44F-F0517F54A627

journal_volume

19

pub_type

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