Photoacoustic microscopy for evaluating a lipopolysaccharide-induced inflammation model in mice.

abstract：:We investigate the optical wavelength dependence in quantitative photoacoustic (QPA) assessment of red blood cell (RBC) aggregation and oxygen saturation (sO2 ) during pulsatile blood flow. Experimentally, the pulsatile flow was imaged with a 700 to 900 nm laser using the VevoLAZR. Theoretically, the photoacoustic (PA...

journal_title：Journal of biophotonics

authors： Bok TH,Hysi E,Kolios MC

更新日期：2018-08-01 00:00:00

abstract：:We combined Michelson-interferometer-based off-axis digital holographic microscopy (DHM) with a common flow cytometry (FCM) arrangement. Utilizing object recognition procedures and holographic autofocusing during the numerical reconstruction of the acquired off-axis holograms, sharply focused quantitative phase images...

journal_title：Journal of biophotonics

authors： Min J,Yao B,Trendafilova V,Ketelhut S,Kastl L,Greve B,Kemper B

更新日期：2019-09-01 00:00:00

abstract：:We report a compact, cost-effective tuned amplifier for frequency-selective amplification of the modulated signal in heterodyne detected nonlinear optical microscopy. Our method improved the signal to noise ratio by an order of magnitude compared to conventional lock-in detection, as demonstrated through stimulated Ra...

journal_title：Journal of biophotonics

authors： Slipchenko MN,Oglesbee RA,Zhang D,Wu W,Cheng JX

更新日期：2012-10-01 00:00:00

abstract：:For a precise manipulation of particles and cells with laser light as well as for the understanding and the control of the underlying processes it is important to visualize and quantify the response of the specimens. Thus, we investigated if digital holographic microscopy (DHM) can be used in combination with microflu...

journal_title：Journal of biophotonics

authors： Kemper B,Langehanenberg P,Höink A,von Bally G,Wottowah F,Schinkinger S,Guck J,Käs J,Bredebusch I,Schnekenburger J,Schütze K

更新日期：2010-07-01 00:00:00

abstract：:Initially, it has been shown that the phase thickness and refractivity (the latter interpreted as the difference of the refractivity indices of an object and surrounding medium) depend on the functional state of mitochondria. The refractivity of various objects decreased in response to energy depletion. This dependenc...

journal_title：Journal of biophotonics

authors： Tychinsky V

更新日期：2009-09-01 00:00:00

abstract：:The fluorescence lifetime of nicotinamide adenine dinucleotide (NADH) is commonly used in conjunction with the phasor approach as a molecular biomarker to provide information on cellular metabolism of autofluorescence imaging of cells and tissue. However, in the phasor approach, the bound and free lifetime defining th...

journal_title：Journal of biophotonics

authors： Ranjit S,Malacrida L,Stakic M,Gratton E

更新日期：2019-11-01 00:00:00

abstract：:Skin fibrosis, often referred to as skin scarring, is a significant international health problem with limited treatment options. The hallmarks of skin fibrosis are increased fibroblast proliferation, collagen production, and migration speed. Recently published clinical observations indicate that visible red light may ...

journal_title：Journal of biophotonics

authors： Mamalis A,Koo E,Garcha M,Murphy WJ,Isseroff RR,Jagdeo J

更新日期：2016-12-01 00:00:00

abstract：:223 Radium (223 Ra) is widely used in nuclear medicine to treat patients with osseous metastatic prostate cancer. In clinical practice 223 Ra cannot be imaged directly; however, gamma photons produced by its short-lived daughter nuclides can be captured by conventional gamma cameras. In this work, we show that 223 Ra ...

journal_title：Journal of biophotonics

authors： Boschi F,De Sanctis F,Spinelli AE

更新日期：2018-04-01 00:00:00

abstract：:The possibilities of using Mueller matrix (MM) imaging polarimetry to assess meat quality have not yet been sufficiently explored. In the current study, the fresh porcine muscles are imaged at room temperature with a wide-field MM imaging polarimeter over 26 hours to visualize dynamics of tissue optical properties thr...

journal_title：Journal of biophotonics

authors： Peyvasteh M,Popov A,Bykov A,Pierangelo A,Novikova T,Meglinski I

更新日期：2020-11-21 00:00:00

abstract：:The broad range of applications of spatially-offset Raman spectroscopy (SORS) were found to involve samples having only marginal differences in Raman cross-sections between the surface and subsurface targets. We report the results of a feasibility study to evaluate the potential of the approach to identify the presenc...

journal_title：Journal of biophotonics

authors： Khan KM,Dutta SB,Krishna H,Majumder SK

更新日期：2016-09-01 00:00:00

abstract：:Single-molecule localisation based super-resolution fluorescence imaging produces maps of the coordinates of fluorescent molecules in a region of interest. Cluster analysis algorithms provide information concerning the clustering characteristics of these molecules, often through the generation of cluster heat maps bas...

journal_title：Journal of biophotonics

authors： Griffié J,Boelen L,Burn G,Cope AP,Owen DM

更新日期：2015-11-01 00:00:00

abstract：:Biophotonics is a highly interdisciplinary field where physicists, chemists, biologists, physicians and engineers work together to solve the problems appearing in biology and medicine. In China, the Biophotonics discipline is often referred to as Biomedical Photonics, under the first-level disciplines Biomedical Engin...

journal_title：Journal of biophotonics

authors： Shi H,Luo Q

更新日期：2017-12-01 00:00:00

abstract：:Laser therapy, also known as Photobiomodulation (PBM) is indicated to reduce pain associated with different pathologies and applied using protocols that vary in wavelength, irradiance and fluence. Its mechanisms of action are still unclear and possibly able to directly impact on pain transmission, reducing nociceptor ...

journal_title：Journal of biophotonics

authors： Zupin L,Ottaviani G,Rupel K,Biasotto M,Zacchigna S,Crovella S,Celsi F

更新日期：2019-10-01 00:00:00

abstract：:In this work we aim to show how it is possible to exploit the second harmonic generation (SHG) signal for producing multimodal microscopic images of biological tissues. SHG microscopy constitutes an important tool for high-resolution, high-contrast, three-dimensional studies of live cell and tissue architectures. The ...

journal_title：Journal of biophotonics

authors： Bianchini P,Diaspro A

更新日期：2008-12-01 00:00:00

abstract：:A murine model of cutaneous leishmaniasis with green fluorescent protein positive (GFP+) L. major enables the monitoring of parasitic load via measurements of GFP fluorescence intensity, allowing for a faster and more efficient way of monitoring the clinical outcome of photodynamic therapy (PDT). This model may provid...

journal_title：Journal of biophotonics

authors： Latorre-Esteves E,Akilov OE,Rai P,Beverley SM,Hasan T

更新日期：2010-06-01 00:00:00

abstract：:Nanofluidics enables the imaging of stretched single molecules with potential applications for single molecule sequence mapping. Lab-on-a-chip devices for single cell trapping and lyzing, genomic DNA extraction from single cells, and optical mapping of genomic length DNA has been demonstrated separately. Yet the pursu...

journal_title：Journal of biophotonics

authors： Marie R,Kristensen A

更新日期：2012-08-01 00:00:00

abstract：:This contribution covers recent original research papers in the biophotonics field. The content is organized into main techniques such as multiphoton microscopy, Raman spectroscopy, infrared spectroscopy, optical coherence tomography and photoacoustic tomography, and their applications in the context of fluid, cell, t...

journal_title：Journal of biophotonics

authors： Krafft C

更新日期：2016-12-01 00:00:00

abstract：:Fluctuations in brain water content has attracted increasing interest, particularly as regards studies of the glymphatic system, which is connected with the complex organization of dural lymphatic vessels, responsible for cleaning tissue. Disturbances of glymphatic circulation are associated with several brain disorde...

journal_title：Journal of biophotonics

authors： Myllylä T,Harju M,Korhonen V,Bykov A,Kiviniemi V,Meglinski I

更新日期：2018-08-01 00:00:00

abstract：:The processes associated with pollen germination were studied in vitro for two tree species, Salix caprea and Fraxinus excelsior under different nutrient conditions. The results provide evidence of changes in chemical composition of the pollen grains during germination. From the comparison of spectra of the pollen gra...

journal_title：Journal of biophotonics

authors： Schulte F,Panne U,Kneipp J

更新日期：2010-08-01 00:00:00

abstract：:5-aminolevulinic acid (ALA) and its methylated ester (MAL) are the most common topical agents used in photodynamic therapy (PDT) as precursors of the photosensitizer protoporphyrin IX (PpIX). The induction of newly PpIX depends on incubation time of each photosensitizer in the tissue and the presence of high intralesi...

journal_title：Journal of biophotonics

authors： Lima CA,Goulart VP,Bechara EJ,Correa L,Zezell DM

更新日期：2016-12-01 00:00:00

abstract：:The content of dermal beta-carotene can be a good indicator showing the body health. Because, it is involved in production of vitamin A maintaining healthy skin and mucous membranes. Also, it reduces the risk of cardiovascular diseases and its antioxidant capacity prevents the formation of cancerous cells. In this wor...

journal_title：Journal of biophotonics

authors： Morovati A,Ansari MA,Tuchin VV

更新日期：2020-09-01 00:00:00

abstract：:Nanosecond pulsed laser irradiation can trigger a release of nucleic acids from gold nanoparticles, but the involved nanoeffects are not fully understood yet. Here we investigate the release of coumarin labeled siRNA from 15 to 30 nm gold particles after nanosecond pulsed laser irradiation. Temperatures in the particl...

journal_title：Journal of biophotonics

authors： Rudnitzki F,Feineis S,Rahmanzadeh R,Endl E,Lutz J,Groll J,Hüttmann G

更新日期：2018-09-01 00:00:00

abstract：:Basidiomycetes, that is, mushroom-type fungi, are known to produce pigments in response to environmental impacts. As antioxidants with a high level of unsaturation, these compounds can neutralize highly oxidative species. In the event of close contact with other microbes, the enzymatically controlled pigment productio...

journal_title：Journal of biophotonics

authors： Tauber JP,Matthäus C,Lenz C,Hoffmeister D,Popp J

更新日期：2018-06-01 00:00:00

abstract：:Photoacoustic microscopy (PAM) provides a fundamentally new tool for a broad range of studies of biological structures and functions. However, the use of PAM has been largely limited to small vertebrates due to the large size/weight and the inconvenience of the equipment. Here, we describe a portable optical-resolutio...

journal_title：Journal of biophotonics

authors： Jin T,Guo H,Yao L,Xie H,Jiang H,Xi L

更新日期：2018-04-01 00:00:00

abstract：:We suggest to use a combination of optical tweezers and single-image quantitative differential interference contrast (DIC) emulated by a spatial light modulator (SLM) to study physiological shape changes in thrombocytes after activation and demonstrate the effectiveness of this system for the given task. A specially d...

journal_title：Journal of biophotonics

authors： Khan S,Jesacher A,Nussbaumer W,Bernet S,Ritsch-Marte M

更新日期：2011-09-01 00:00:00

abstract：:Ionizing radiation (IR) induces DNA damage and low-level laser therapy (LLLT) has been investigated to prevent or repair detrimental outcomes resulting from IR exposure. Few in vitro studies, however, explore the biological mechanisms underlying those LLLT benefits. Thus, in this work, fibroblasts and tumor cells are ...

journal_title：Journal of biophotonics

authors： Ramos Silva C,Cabral FV,de Camargo CF,Núñez SC,Mateus Yoshimura T,de Lima Luna AC,Maria DA,Ribeiro MS

更新日期：2016-12-01 00:00:00

abstract：:The purpose of this study was to evaluate early vascular and tomographic changes in the retina of diabetic patients using artificial intelligence (AI). The study included 74 age-matched normal eyes, 171 diabetic eyes without retinopathy (DWR) eyes and 69 mild non-proliferative diabetic retinopathy (NPDR) eyes. All pat...

journal_title：Journal of biophotonics

authors： Govindaswamy N,Ratra D,Dalan D,Doralli S,Tirumalai AA,Nagarajan R,Mochi T,Shetty N,Sinha Roy A

更新日期：2020-09-01 00:00:00

abstract：:Therapeutically exploiting vascular and metabolic endpoints becomes critical to translational cancer studies because altered vascularity and deregulated metabolism are two important cancer hallmarks. The metabolic and vascular phenotypes of three sibling breast tumor lines with different metastatic potential are inves...

journal_title：Journal of biophotonics

authors： Zhu C,Li M,Vincent T,Martin HL,Crouch BT,Martinez AF,Madonna MC,Palmer GM,Dewhirst MW,Ramanujam N

更新日期：2019-04-01 00:00:00

abstract：:The purpose of this study was to evaluate thermal and near-infrared (NIR) reflectance imaging methods for the assessment of the activity of root caries lesions. In addition, changes in the lesion structure were monitored with polarization sensitive optical coherence tomography (PS-OCT). Artificial bovine and natural r...

journal_title：Journal of biophotonics

authors： Lee RC,Darling CL,Staninec M,Ragadio A,Fried D

更新日期：2017-03-01 00:00:00

abstract：:Surface-enhanced Raman scattering (SERS) spectroscopy possesses the most promising advantage of multiplex detection for biosensing applications, which is achieved due to the narrow 'fingerprint' Raman spectra from the analyte molecules. We developed an ultrasensitive platform for the multiplex detection of cancer biom...

journal_title：Journal of biophotonics

authors： Dinish US,Balasundaram G,Chang YT,Olivo M

更新日期：2014-11-01 00:00:00