Abstract:
:The effects of blockade of dopaminergic receptors as well as the lesions of dopaminergic neurons on the behaviour of rats in "motivational" and "motor" tests were examined. Both systemic injection of haloperidol and 6-OHDA lesions in the ventral tegmental area (VTA) or substantia nigra, pars compacta (SN/pC) induced a decrease in the number of wins made by thirsty animals fighting for water in a water competition test. The rats with lesions in the VTA became insensitive to motivational thirst stimuli. The reaction of rats lesioned in the SN/pC was still dependent on the level of thirst. Both groups did not differ from controls in the amount of water intake. In the rotating rod test the animals with destroyed nigrostriatal system showed a substantial motor impairment, while destruction of the mesolimbic system had no effect in that test. The role of dopaminergic systems in terms of their involvement in the control of motivational arousal and motor performance has been discussed.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Papp M,Bal Adoi
10.1016/0031-9384(86)90042-9subject
Has Abstractpub_date
1986-01-01 00:00:00pages
773-9issue
6eissn
0031-9384issn
1873-507Xpii
0031-9384(86)90042-9journal_volume
38pub_type
杂志文章abstract::There are several techniques used to measure body composition in experimental models including dual energy X-ray absorptiometry (DEXA) and quantitative magnetic resonance (QMR). DEXA/QMR data have been compared in mice, but have not been compared previously in rats. The goal of this study was to compare DEXA and QMR d...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2010.12.004
更新日期:2011-04-18 00:00:00
abstract::In 1975, at the start of my junior year in college, I took a course on experimental methods in psychology from Dr. James C. Smith, when he was a Visiting Professor at Penn State University. That experience set me on the professional path of studying the neural bases of taste function and ingestion on which I remain to...
journal_title:Physiology & behavior
pub_type: 历史文章,杂志文章
doi:10.1016/j.physbeh.2015.04.026
更新日期:2015-12-01 00:00:00
abstract::Twenty-four-hour recordings of electrophysiological correlates of the sleep-waking cycle in the rat were performed during different stages of cuff pedestal treatment. It was found that rats adapted to live on pedestals with the cuff raised displayed undisturbed patterns of sleep and wakefulness. Lowering the cuff for ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(84)90283-x
更新日期:1984-06-01 00:00:00
abstract::The effects of daily single injections of 20 mg/kg cocaine on locomotor activity, core temperature, and heart rate were determined by radiotelemetry. There was a progressive increase in locomotor activity over the 30-day treatment period. Cocaine-induced activity was 9-12-fold greater than that of saline-treated anima...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(96)00250-8
更新日期:1996-11-01 00:00:00
abstract::The objective of this study was to determine whether humans could detect long-chain fatty acids when these lipid molecules are delivered to the oral cavity by edible taste strips. For suprathreshold studies, up to 1.7 μmol of stearic acid or linoleic acid was incorporated into 0.03 mm thick, one-inch square taste stri...
journal_title:Physiology & behavior
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.physbeh.2012.04.006
更新日期:2012-07-16 00:00:00
abstract::Ghrelin, an acylated upper gastrointestinal peptide, is the only known orexigenic hormone. Considerable evidence implicates ghrelin in mealtime hunger and meal initiation. Circulating levels decrease with feeding and increase before meals, achieving concentrations sufficient to stimulate hunger and food intake. Prepra...
journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/j.physbeh.2006.05.022
更新日期:2006-08-30 00:00:00
abstract::Applying high temperature cooling concepts, i.e. high temperature cooling (T(supply) is 16-20°C) HVAC systems, in the built environment allows the reduction in the use of (high quality) energy. However, application of high temperature cooling systems can result in whole body and local discomfort of the occupants. Non-...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2012.07.008
更新日期:2012-09-10 00:00:00
abstract::Twenty-one healthy volunteers took part in the study, the aim of which was to determine the influence of acute pain on skin impedance, skin temperature and heart rate. Acute pain was induced by cold exposure. Skin impedance, heart rate and facial skin temperature were recorded before, during and after the painful stim...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(90)90064-b
更新日期:1990-01-01 00:00:00
abstract::The present studies sought to determine whether prenatal cocaine administration (15 mg/kg b.i.d. between gestational ages 1-20) had enduring effects on emotional behavior of rats. Rats prenatally treated with cocaine interacted less with other rats in the social interaction test of anxiety at both 30 and 120 days of a...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(00)00245-6
更新日期:2000-07-01 00:00:00
abstract:BACKGROUND:This cohort study evaluates whether the association between low-grade inflammation and incident depressive symptoms is independent of abdominal obesity and metabolic disturbances. METHODS:A cohort of 1167 non-depressed men aged 35 to 80 years were followed up over 5 years to assess incident depressive sympt...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2014.11.058
更新日期:2015-02-01 00:00:00
abstract::Recent research suggests that gratitude is associated with better cardiovascular health. Here, we investigated whether trait and/or state gratitude was associated with cardiovascular responses to acute stress. Eighty-six young adults completed measures of gratitude and had their cardiovascular responses monitored thro...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2020.112896
更新日期:2020-07-01 00:00:00
abstract::Sexual behavior in female rats is dependent on gonadal steroids. In ovariectomized rats, progesterone treatment typically exerts a biphasic effect on copulatory behavior induced by prior treatment with estradiol. Thus, there is an initial augmentation of the facilitative effect of estradiol occurring 4-10 h after prog...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90378-f
更新日期:1992-11-01 00:00:00
abstract:OBJECTIVE:Epilepsy is the most common neurological chronic condition worldwide, affecting about 2% of world population. Temporal lobe epilepsy (TLE) reaches 40% of all cases of this condition, and it is highly refractory to pharmacological treatment. Physical activity has been suggested as complementary therapy for epi...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2016.12.040
更新日期:2017-03-15 00:00:00
abstract::To extend our previous study on the behavioral effects of testosterone propionate (TP) and dihydrotestosterone propionate (DHTP) to a dose-range producing supra-physiological plasma androgen levels, 4 castrated cynomolgus monkeys were tested with the same 4 females during successive 4-week treatment periods while rece...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(87)90040-0
更新日期:1987-01-01 00:00:00
abstract::Compared were the light-dark pattern of absolute energy intake and macronutrient selection of male Wistar rats intracerebroventricularly infused with glucagon (5 ng/h) or saline for 7 days in a three-way selection of macronutrients. Glucagon infusion induced a decrease in 24 h and nocturnal energy intake, whereas no s...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(95)02108-6
更新日期:1996-02-01 00:00:00
abstract::Schedule-induced polydipsia was studied in rats on a variable second-order schedule in Experiments 1 and 2. Drinking occurred only following presentations of the pellet reinforcer and was not induced by a stimulus that was associated with pellet delivery. Moreover, it was shown that lever pressing for food was not com...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(75)90158-4
更新日期:1975-02-01 00:00:00
abstract::Pretreatment with the GABA(A) receptor antagonist, bicuculline or the GABA(B) receptor antagonist, saclofen, into the nucleus accumbens (Nacc) shell, respectively, potentiates and reduces feeding elicited by the mu opioid agonist, [D-Ala(2), Nme(4), Gly-ol(5)]-enkephalin (DAMGO), administered into the same site. DAMGO...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(03)00087-8
更新日期:2003-07-01 00:00:00
abstract::It has been recognized for some time that a number of different neuropeptides exert powerful effects on food intake. During the last few years, the neurocircuitry within which these peptides operate has also begun to be elucidated. Peptidergic feeding-regulatory neurones are found both in the hypothalamus and the brai...
journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/s0031-9384(01)00611-4
更新日期:2001-11-01 00:00:00
abstract::Male rats, fitted with indwelling gastric fistulas, were tested with either a closed fistula (normal drinking) or an open fistula (sham drinking) following either intracellular dehydration (with NaCl), extracellular dehydration (with PEG), or the combination of the two stimuli. In normal drinking tests, the combined s...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(90)90068-f
更新日期:1990-04-01 00:00:00
abstract::Although the involvement of two types of vasopressin (AVP) receptors, v1a and v1b, in neural regulation of social behavior is well documented in rodents, there is no report on combined actions of them in regulation of social behavior. In this study, we investigated behavioral differences between wild-type (WT) and v1a...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2018.09.016
更新日期:2018-12-01 00:00:00
abstract::Any odor-guided behavior might require generalization and/or discrimination over a wide range of odorant intensities. Proboscis extension conditioning (PEC) and electroantennogram (EAG) assays were used to investigate stimulus-intensity dynamics during olfactory processing in the honey bee. Experiments that tested gen...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(96)00357-5
更新日期:1997-01-01 00:00:00
abstract::Sedentary, adult rats of both sexes fed Purina chow and a 32% sucrose solution overate, gained excess weight and had higher Lee Indexes of obesity than control animals fed only Purina chow. The magnitude of these effects was similar in the males and females. Animals of both sexes fed the sucrose diet showed a slower r...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(82)90012-9
更新日期:1982-08-01 00:00:00
abstract::Bariatric surgery is an effective treatment for obesity that involves both peripheral and central mechanisms. To elucidate central pathways by which oral and visceral signals are influenced by high-fat diet (HFD) and Roux-en-Y gastric bypass (RYGB) surgery, we recorded from neurons in the caudal visceral nucleus of th...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2015.07.025
更新日期:2015-12-01 00:00:00
abstract::The purpose of this study was to examine the interchangeability of a new perceived recovery status scale (PRS) of 100 points through a comparison to the original 10-point version. This study also aimed to test the interchangeability of CR100 scale (Borg's rate of perceived exertion scale) in comparison to the CR10. Tw...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2019.112641
更新日期:2019-10-15 00:00:00
abstract::Rats given restricted feeding and allowed free access to activity wheels increase activity, decrease food intake, and lose body weight compared to nonexercised controls. The phenomenon is of interest because of the relationship between exercise and anorexia nervosa. This study determined if another factor that energiz...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(93)90161-8
更新日期:1993-03-01 00:00:00
abstract::Ibotenic acid (IBO) is assumed to lesion neurons and to spare fibers of passage. The effects of such lesions in the amygdaloid complex of rats were compared to those of radio frequency lesions (RF) on a passive avoidance task. Both lesions impaired the acquisition of the passive avoidance response. Plasma corticostero...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(85)90119-2
更新日期:1985-02-01 00:00:00
abstract::Rats' voluntary ethanol intake varies with dispositional factors and energy status. The joint influences of these were of interest here. We previously reported that rats selectively bred for high voluntary saccharin intake (HiS) consume more ethanol and express more robust conditioning of preference for flavors paired...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2012.12.001
更新日期:2013-01-17 00:00:00
abstract::In vivo voltammetry has been widely employed to monitor the effects of drugs on dopamine metabolism. In the present study, we report on the use of a newly designed assembly for implantation of carbon fiber microelectrodes for voltammetric measurements in freely moving animals. The assembly consists of an electrode hol...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(87)90357-x
更新日期:1987-01-01 00:00:00
abstract::The 'post-lunch' dip is a bi-circadian phenomenon, largely unrelated to lunch, and worsened by a disturbed prior night's sleep. Despite anecdotal claims of adverse effects of larger lunches on afternoon driving ability, there is little actual driving data to support this belief. Although there have been various (non-d...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2011.11.025
更新日期:2012-02-28 00:00:00
abstract::Non-parturient female rats were primed with oestrogen and given 5 minutes of vaginal-cervical stimulation before foster pups were introduced to them. Virgin and multiparous Wistar rats were used and half the females were ovariectomised. Half of each group was given vaginal-cervical stimulation and the other half was h...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(86)90378-1
更新日期:1986-01-01 00:00:00