Abstract：
:Sedentary, adult rats of both sexes fed Purina chow and a 32% sucrose solution overate, gained excess weight and had higher Lee Indexes of obesity than control animals fed only Purina chow. The magnitude of these effects was similar in the males and females. Animals of both sexes fed the sucrose diet showed a slower rate of weight loss during food deprivation than the chow controls. Access to an activity wheel led to a reduction in caloric intake and the elimination of obesity in male rats. In the chow fed male rats activity led to a smaller, transient suppression in caloric intake and a slightly lower level of body weight than the sedentary chow controls. Access to activity did not affect body weight in the female rats in either dietary condition. Rather, both active groups of female rats appeared to compensate for the energy cost of voluntary activity by a small increase in food consumption. Long-term exposure to activity was associated with more rapid weight loss during food deprivation in both males and females. These data reveal that high levels of activity and obesity can co-exist when normal female rats are fed a palatable diet but that activity eliminates this form of obesity in the male rat.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Hirsch E,Ball E,Godkin Ldoi
10.1016/0031-9384(82)90012-9subject
Has Abstractpub_date
1982-08-01 00:00:00pages
253-62issue
2eissn
0031-9384issn
1873-507Xpii
0031-9384(82)90012-9journal_volume
29pub_type
杂志文章abstract：:The circadian rhythm of hamster locomotor activity "splits" into two distinct circadian components during conditions of constant illumination. To determine if the circadian rhythm of body temperature also splits under these conditions, body temperature and locomotor activity were monitored concurrently in animals hous...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(84)90191-4
更新日期：1984-05-01 00:00:00
abstract：:Rats exposed to a relatively high dose (7.5 g/kg body weight) of alcohol on either the fifth or tenth postnatal day of age have been reported to have long-lasting deficits in spatial learning ability as tested on the Morris water maze task. The question arises concerning the level of alcohol required to achieve this e...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00424-1
更新日期：1998-01-01 00:00:00
abstract：:Rats' voluntary ethanol intake varies with dispositional factors and energy status. The joint influences of these were of interest here. We previously reported that rats selectively bred for high voluntary saccharin intake (HiS) consume more ethanol and express more robust conditioning of preference for flavors paired...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2012.12.001
更新日期：2013-01-17 00:00:00
abstract：:The objective of the study was to confirm the satiety/energy intake effect of a novel fat emulsion (Olibra) versus placebo in the short term. A randomized, double-blind, placebo-controlled, crossover design was used. 41 subjects participated in the study (n=21: junior-normal weight: age 23.7+/-2.8 years; BMI: 22.0+/-1...
journal_title：Physiology & behavior
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.physbeh.2008.05.006
更新日期：2008-09-03 00:00:00
abstract：BACKGROUND:Previous research has reported no effect of exercise modality (aerobic vs. resistance) on energy intake (EI). However, the relatively low energy cost of resistance training, the absence of total energy expenditure (TEE) measurements and the short duration of these studies justify further investigation. OBJE...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.03.031
更新日期：2014-05-10 00:00:00
abstract：:Food preference and fish-attractive parameters were studied on 1000 15- to 18-month-old Nile crocodiles, using two-choice preference tests. All three experimental groups preferred live fish over dead fish and live chicks, while ground meat was the last choice. As for fish attractiveness, motion, freshness, size, color...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(91)90489-b
更新日期：1991-07-01 00:00:00
abstract：:The regulation of food and fluid intake in lactating women was examined by comparing maternal intake during lactation, 6 weeks postpartum, to intake in two groups of nonpregnant, nonlactating women. All subjects completed a questionnaire and then filled out a food-intake diary for seven consecutive days. Lactating wom...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(93)90071-m
更新日期：1993-10-01 00:00:00
abstract：:During later life sleep depth (slow-wave sleep, SWS) and maintenance exhibit deleterious changes, with possible negative effects on daytime function. This study assessed the effect of chronic, supervised exercise on sleep using laboratory-based polysomnography (PSG) and repeated measures in older adults. Thirteen men ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.12.031
更新日期：2015-03-01 00:00:00
abstract：:Central manipulation of neuromodulators is critical to establishing causal links between brain function and behavioral output. The absence of a rigorous method of evaluating intracerebroventricular (i.c.v.) injection efficacy in small model organisms is one reason why peripheral administration of neuroactive substance...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2012.04.017
更新日期：2012-07-16 00:00:00
abstract：:The effects of pinealectomy on locomotor behavior responses to cold, heat or pain were assessed in freely moving rats. External cold (4 degrees C) or heat (36 degrees C) stress produced increases of locomotion (including horizontal and vertical movement, and total distance traveled), increases of number of turnings (i...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(94)90120-1
更新日期：1994-03-01 00:00:00
abstract：:KINSEY, S. G., BAILEY, M. T., SHERIDAN, J. F., PADGETT, D. A. The inflammatory response to social defeat is increased in older mice. PHYSIOL BEHAV 91(0) 000-000, 2007. Previous research indicates that repeated social defeat of mice causes increased lymphocyte trafficking to the spleen, elevated proinflammatory cytokin...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2007.11.003
更新日期：2008-02-27 00:00:00
abstract：:We examined the effects of 30 min of cycling exercise at a moderate intensity of 50% peak oxygen uptake, compared to 30 min of rest, on changes in emotional responses to pictorial foreground stimuli that reliably elicit unpleasant, neutral, and pleasant affect. Emotional responses were measured by self-reports of vale...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2006.10.001
更新日期：2007-02-28 00:00:00
abstract：:To test the hypothesis that hepatic vagal afferents mediate the satiety effect of pancreatic glucagon, we tested the effects of selective surgical and pharmacological lesions of the abdominal vagus on glucagon's potency to inhibit feeding. Surgical disconnection of only the hepatic branch of the abdominal vagus blocke...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(83)90207-x
更新日期：1983-09-01 00:00:00
abstract：:Although female aggression is found in many species and in a variety of contexts, little is known about its physiological bases. To compare neuroendocrine responses to aggression in females and males, we staged aggressive interactions between free-living territorial mountain spiny lizards and same-sex intruders and me...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(00)00345-0
更新日期：2000-11-01 00:00:00
abstract：:The present experiment was designed to determine if intromissions alone could induce a reward state as evaluated by conditioned place preference (CPP). We also compared the rewarding properties of one ejaculation and a morphine injection. We evaluated if intromissions alone could induce CPP in males with one or three ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2009.09.012
更新日期：2009-12-07 00:00:00
abstract：:Numerous studies have dealt with the role of opiate system in tasks aimed at measurement of cognitive behavior, but the role of morphine dependence on learning and memory is still controversial. In this study chronic exposure to morphine was employed to evaluate learning ability and spatial short-term memory (working ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2007.11.002
更新日期：2008-02-27 00:00:00
abstract：:Pleasant and unpleasant flavors and odors can modulate pain perception, and the efficacy of sweet flavors in reducing pain seems to be related to its hedonic value. Chronic variate stress paradigm is a model of depression, and is suggested to induce anhedonia. We observed previously that lithium may prevent behavioral...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2006.04.004
更新日期：2006-07-30 00:00:00
abstract：:Rats shifted from a 32% to 4% sucrose solution consume substantially less 4% sucrose than unshifted animals that experience only the 4% solution. This negative contrast effect was found to be attenuated by lesions of the lateral aspects of the amygdala (basolateral, lateral, and basomedial nuclei) and eliminated by le...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(84)90035-0
更新日期：1984-11-01 00:00:00
abstract：:In addition to the well-known activation of the pituitary-adrenal axis, acute exposure to severe stressors includes a temporary analgesia in rats. Thus, the present study investigates whether the pituitary was involved in the mediation of analgesia induced by severe cold-water swim (CWS) stress. Flinch-jump thresholds...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(79)90122-7
更新日期：1979-07-01 00:00:00
abstract：:Alzheimer's disease (AD) is one of the major neurological diseases of the elderly. How to safely and effectively remove the toxic Aβ42 peptide through blood-brain barrier (BBB) is considered to be an effective method for the prevention and treatment of AD. The compounds whose molecule weight is less than 400 Da and th...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.11.016
更新日期：2015-02-01 00:00:00
abstract：BACKGROUND:There is no consensus about how resilience is related to the different types of stress such as daily or chronic stress and psychopathology. The main objective of this study is to evaluate the relationship between resilience and the different measures of stress such as perceived stress, chronic stress, life e...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.02.001
更新日期：2019-04-01 00:00:00
abstract：:Fatigue is common in a host of neurological and psychiatric disorders including depression and often continues unabated even after primary symptoms of disease are treated. Its high estimated prevalence combined with the lack of effective medicines has engaged the preclinical research community to search for fatigue mo...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2018.11.042
更新日期：2019-02-01 00:00:00
abstract：:Body temperature (Tb) was monitored telemetrically in adult deer mice kept in an environmental chamber at low ambient temperature (Ta = 15 degrees C). Mice were challenged with various doses of 2-deoxy-D-glucose (2DG, a glycolysis inhibitor) or mercaptoacetate (MA, a fatty acid oxidation inhibitor) or a combination of...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(96)00495-7
更新日期：1997-04-01 00:00:00
abstract：:Neonatal capsaicin treatment (50 mg/kg SC in two-day-old rats) increased thermal pain thresholds in both sexes when measured at different ages, decreased the responsiveness of adult females to specific noxious stimulation, and differentially decreased the magnitude of vaginocervical stimulation (VS)-produced analgesia...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(91)90412-h
更新日期：1991-11-01 00:00:00
abstract：:There is evidence that alterations in heart rate and blood pressure variability (BPV) are associated with cardiovascular disease. We used a mice model to investigate the effects of acute and chronic stress on blood pressure variability (BPV) and heat rate variability (HRV). Shaker stress was given acutely (5 min, 150 ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2004.08.004
更新日期：2004-10-30 00:00:00
abstract：:Male Wistar rats living in colonies of 4 males plus 4 females were compared to noncolony males, cohabitating with a female. Irreversible dominance relationships developed between one dominant male (D) and three subordinates (S). Dominants developed high basal testosterone levels and large preputial glands. Subordinate...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90078-g
更新日期：1992-05-01 00:00:00
abstract：:In the following experiments, an attempt was made to determine the role of the ovary in the control of food intake and body weight regulation during lactation. In the first study, it was found that concentrations of estradiol benzoate effective in suppressing food intake and body weight in nonlactating animals were no...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(76)90016-0
更新日期：1976-12-01 00:00:00
abstract：:Midbrain raphe lesions induced aggressive behavior which was characterized by defensive aggression rather than offensive aggression in nature. Furthermore, raphe-lesioned rats exhibited muricide. This muricide included not only mouse-killing but also mouse-eating behavior. Both dorsal and medial raphe lesioned (dm-R) ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(77)90166-4
更新日期：1977-07-01 00:00:00
abstract：:The results of several studies strongly indicate a bidirectional relationship among gonadal hormones and pain. While gonadal hormones play a key role in pain modulation, they have been found to be affected by pain therapies in different experimental and clinical conditions. However, the effects of pain and pain therap...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2012.12.014
更新日期：2013-02-17 00:00:00
abstract：:Rats are nocturnal feeders. The present results show that when either the cost of procuring a meal or the cost of consuming it increases differentially in the dark relative to the light, rats shift their feeding activity to the light phase of the light/dark cycle. These results suggest that some of the same factors th...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(83)90081-1
更新日期：1983-10-01 00:00:00
