Short-term effects of a novel fat emulsion on appetite and food intake.

Abstract:

:The objective of the study was to confirm the satiety/energy intake effect of a novel fat emulsion (Olibra) versus placebo in the short term. A randomized, double-blind, placebo-controlled, crossover design was used. 41 subjects participated in the study (n=21: junior-normal weight: age 23.7+/-2.8 years; BMI: 22.0+/-1.6 kg/m(2); n = 20: senior-overweight: age 43.6+/-4.9 years; BMI: 27.7+/-1.6 kg/m(2)). An energy intake and satiety test (with questionnaires) took place on 2 occasions, with placebo or test yoghurt as breakfast. In the junior-normal weight subjects, consumption of test yoghurt reduced hunger and desire to eat during the morning (area under curve, p<0.05) and increased the time elapsed between consumption of the yoghurt and the point at which hunger scores returned to baseline; 234+/-79 min in the test condition compared to 174+/-58 min in the placebo condition (p<0.05). No significant differences in appetite scores between the test and placebo yoghurt were seen for the senior-overweight subjects. No effect on energy intake was seen in the total group, in the junior-normal weight and senior-overweight subjects. In conclusion, the Olibra emulsion exerted a suppressive effect on the area under the curve of appetite ratings over 3 h in normal weight women aged 18 to 30 years. The Olibra emulsion did not affect subsequent energy intake in either group.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Diepvens K,Steijns J,Zuurendonk P,Westerterp-Plantenga MS

doi

10.1016/j.physbeh.2008.05.006

subject

Has Abstract

pub_date

2008-09-03 00:00:00

pages

114-7

issue

1-2

eissn

0031-9384

issn

1873-507X

pii

S0031-9384(08)00154-6

journal_volume

95

pub_type

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