Abstract：
:To extend our previous study on the behavioral effects of testosterone propionate (TP) and dihydrotestosterone propionate (DHTP) to a dose-range producing supra-physiological plasma androgen levels, 4 castrated cynomolgus monkeys were tested with the same 4 females during successive 4-week treatment periods while receiving 800 micrograms, 1.6 mg, 3.2 mg, 6.4 mg and 12.8 mg of TP or DHTP SC/day in counterbalanced order (16 pairs, 828 1-hr tests). Both androgens increased male sexual activity, but DHTP was less effective than TP in increasing the numbers of ejaculations per test and failed to restore ejaculations to intact levels. Giving androgen-treated males single injections of 50 micrograms and 100 micrograms estradiol benzoate (EB) was without any additional effect on behavior (16 pairs, 256 tests). To examine hormonal effects in the brain, castrated males were given either 3H-T or 3H-DHT, and tissues were examined by high performance liquid chromatography (hplc). After 3H-T, 3H-E2 and unchanged 3H-T were the major forms of radioactivity in nuclei from hypothalamus, preoptic area and amygdala. After 3H-DHT, unchanged 3H-DHT predominated. The lower behavioral effectiveness of DHT could not be ascribed to its failure to enter the brain. The data suggested a role for unchanged T in the regulation of ejaculatory behavior in a male primate.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Michael RP,Bonsall RW,Zumpe Ddoi
10.1016/0031-9384(87)90040-0subject
Has Abstractpub_date
1987-01-01 00:00:00pages
527-37issue
4eissn
0031-9384issn
1873-507Xpii
0031-9384(87)90040-0journal_volume
40pub_type
杂志文章abstract：BACKGROUND:There is no consensus about how resilience is related to the different types of stress such as daily or chronic stress and psychopathology. The main objective of this study is to evaluate the relationship between resilience and the different measures of stress such as perceived stress, chronic stress, life e...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.02.001
更新日期：2019-04-01 00:00:00
abstract：:In nature the degu has been observed to deposit and to investigate scents. This study employed a captive group of these animals to investigate their responses to conspecific urinary marks in a neutral arena. Both sex classes served as subjects. They were presented with urine obtained from males, from females and a sal...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(85)90027-7
更新日期：1985-06-01 00:00:00
abstract：:Mice are impaired relative to rats in place and matching-to-place learning when tests are given in a swimming pool. The rat advantage may stem from a superior spatial ability or from adaptation to a niche that has prepared them for competency in the water. In the present study, mice (C57BL/6) were compared with rats (...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(96)00176-x
更新日期：1996-11-01 00:00:00
abstract：:Bilateral intracranial injections of puromycin (10 micrograms/0.5 microliter vehicle) into the preoptic area (POA) of steroid-primed ovariectomized rats resulted in a significant decrease in the lordosis response when compared to saline treated controls. To determine the extent of puromycin diffusion after intracrania...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(84)90162-8
更新日期：1984-09-01 00:00:00
abstract：:Cage stocking density can be manipulated by changing in cage size and group size in the cage. The effects of these two factors were investigated in three developmental stages in male rats: juvenile, post-pubertal, and adult. An open-field test was conducted to measure exploratory behavior which was influenced by level...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2005.01.008
更新日期：2005-03-16 00:00:00
abstract：:Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) are adrenal androgens that have been associated with a sense of well-being in humans. We describe two experiments done to test the hypothesis that an increase in DHEA or DHEAS secretion is associated with the inclination to exercise using a hamst...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(99)00108-0
更新日期：1999-10-01 00:00:00
abstract：:There is increasing evidence, both electrophysiological and behavioral, that bitter and sweet stimuli drive parallel pathways in the gustatory brainstem. Here we report two lines of investigation that suggest significant interactions among these parallel systems. First, responses recorded from single cells in the hams...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(94)90365-4
更新日期：1994-12-01 00:00:00
abstract：UNLABELLED:Monosodium glutamate (MSG), a flavor enhancer used in food, administered to neonatal rats causes neuronal lesions and leads to anxiety when adulthood. AIMS:We investigated the anxiolytic-like effect of diphenyl diselenide (PhSe)2 and its mechanisms on anxiety induced by MSG. MAIN METHODS:Neonatal male and ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2015.11.038
更新日期：2016-03-01 00:00:00
abstract：:The 24-hour sleep-wake cycle of untreated, normal rats and of capsaicin-treated rats was continuously recorded by telemetry. Recordings were made on two baseline days at 22 degrees C, two days at 29 degrees C, and two final days at 22 degrees C. In untreated animals the daily amount of waking was reduced by the elevat...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(83)90148-8
更新日期：1983-03-01 00:00:00
abstract：:Siberian hamsters (Phodopus sungorus) increase food hoarding, but not food intake, after a fast. Because the physiological mechanisms underlying these changes in food hoarding are virtually unknown, we sought insight into these mechanisms by allowing hamsters to self-select their diet from food sources varying in macr...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(99)00167-5
更新日期：1999-12-01 00:00:00
abstract：:The purpose of the present study was to determine the effects of restricting food and water intake to the light period on sleep and brain temperature (Tbr). Sprague-Dawley male rats were anesthetized and provided with electrodes and thermistors for electroencephalographic (EEG) and Tbr recordings. Baseline recordings ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(99)00137-7
更新日期：1999-11-01 00:00:00
abstract：:The role of protein, carbohydrate and fat ingestion on self-rated mood and subsequent food intake was investigated using self-reports of spontaneous food intake. Eight male and 30 female undergraduate students were instructed to list everything they ate, when they ate it, and their mood at the time of ingestion. They ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(87)90154-5
更新日期：1987-01-01 00:00:00
abstract：:Alcohol dehydrogenases (ADH) are key enzymes of ethanol metabolism that mediate its oxidation to acetaldehyde. ADHs are also able to oxidize some types of neurotransmitters such as dopamine, serotonin and norepinephrine. Increased level of ADHs activity, induced by chronic alcohol consumption, is presumably associated...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2017.07.022
更新日期：2017-10-01 00:00:00
abstract：:Twenty-four-day old weanling male and female rats were either lesioned in the septal area, gonadectomized, lesioned and gonadectomized, or untreated. Tests for reactivity to electric shock were conducted at 26 and at 40 days of age. Neither males nor females showed any effect of the lesions are measured by flinch and ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(77)90046-4
更新日期：1977-11-01 00:00:00
abstract：:To study some metabolic features during feeding in food-restricted rats two groups of animals were maintained on a 2 hr feeding/22 hr fast schedule. Group D (n = 38) received a meal every day from 8:00 to 10:00 a.m. Group N (n = 34) was given the meal from 8:00 to 10:00 p.m. The average total amount of food ingested b...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(85)90399-3
更新日期：1985-11-01 00:00:00
abstract：:Disruption of attachment relations in early life is linked to greater vulnerability to depressive illness at later ages. Evidence suggests this process involves stress-induced activation of central inflammatory factors, though the specific mediators and processes involved are not known. We used a guinea pig model in w...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2018.11.040
更新日期：2019-02-01 00:00:00
abstract：:Sheep of calm or nervous temperament differ in their physiological (cortisol secretion) and behavioural (motor activity) responses to stressors, perhaps due to variation in genes that regulate glucocorticoid synthesis or brain dopamine activity. Using ewes that had been selected over 20 generations for nervous (n=58) ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2015.10.022
更新日期：2016-01-01 00:00:00
abstract：:We studied the effects of the androgenic hormone, androsterone sulfate, a 17-ketosteroid, on long term potentiation in the dentate gyrus (DG) of urethane anesthesized rats. Intravenous injection of 10 mg of the hormone dissolved in Nutralipid produced a significant increase of the population spike (PS), but not of the...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(00)00354-1
更新日期：2000-12-01 00:00:00
abstract：:Endothelium-aggressive factors are associated with the development of atherosclerosis. Exercise training can either prevent or attenuate this process, but little is known about the effects of high-intensity interval training (HIIT) in adolescents. Thus, we assessed the effects of HIIT on endothelial function, lipid pr...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.112728
更新日期：2020-01-01 00:00:00
abstract：:The Mashona mole rat, Cryptomys darlingi, is a social, subterranean African rodent that is rarely, if ever, exposed to light, and that exhibits a regressed visual system. This study investigated locomotor activity patterns of Mashona mole rats (n=12) under different light cycles. Activity was measured using either inf...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2004.11.005
更新日期：2005-02-15 00:00:00
abstract：:Thermoregulatory behavior and feeding status are strongly related in ectotherms. A trade-off between maintenance of energy balance and digestion efficiency has been recently proposed to affect thermoregulation in these animals. On the other hand, competition for basking sites has been described between Iberian turtles...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2011.12.020
更新日期：2012-03-20 00:00:00
abstract：:Unlike rats, Siberian hamsters exhibit seasonal changes in energy balance that are controlled by the photoperiod (daylength). In Siberian hamsters, body weight and fat, and food intake peak in long, summer-like days and reach nadirs in short, winter-like days. The purpose of the present experiments was to test whether...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(94)00203-h
更新日期：1995-01-01 00:00:00
abstract：:We have previously reported that the opioid receptor blocker, naloxone, is less effective in reducing palatable food intake in offspring exposed to a maternal cafeteria diet during the perinatal period, implicating a desensitization of the central opioid pathway in the programming of food preferences. The present stud...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.04.007
更新日期：2014-06-22 00:00:00
abstract：:Weight gain and appetite regulation are complex interplays between internal and external cues. Our aim was to investigate the association of eating behaviors with ghrelin taking into account lifestyle. We conducted a cross-sectional analysis in a sample of first-year university students at the Université de Sherbrooke...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2011.04.013
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:Otitis media (OM), or middle ear infections, are one of the most common diseases during early childhood. OM has been linked to changes in food preferences through potential effects on taste signalling, and thereby, to increased weight. OBJECTIVES:We investigated the associations between OM, taste sensitivit...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.112570
更新日期：2019-09-01 00:00:00
abstract：:Three different techniques were used to study the effects of 72 hr deprivation of paradoxical sleep on percentages total sleep, light slow wave sleep, deep slow wave sleep and paradoxical sleep during deprivation and recovery periods in rats. The paradoxical sleep deprivation methods used were the classical platform, ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(86)90341-0
更新日期：1986-01-01 00:00:00
abstract：:The aim of the study was to investigate the illuminance selected in the morning by subjects whose face was cooled and whose tympanic temperature has been lowered by 0.15-0.25 degrees C. The hypothesis tested was that a difference between the actual core temperature and its set point (load error) will influence the pre...
journal_title：Physiology & behavior
pub_type： 临床试验,杂志文章
doi：10.1016/j.physbeh.2003.12.015
更新日期：2004-03-01 00:00:00
abstract：:A large body of evidence suggests that endogenous opioids are involved in the regulation of feeding. As the striatum and globus pallidus have relatively high concentrations of opioid receptors, these areas are possible sites of action for the stimulatory effects of opiates on feeding. To test these possibilities, male...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(84)90153-7
更新日期：1984-09-01 00:00:00
abstract：:The subfornical organ (SFO), as one of the sensory circumventricular organs (CVOs), is among the only central nervous system structures which interfaces directly with circulating substances that do not cross the blood brain barrier. Here we describe a growing literature showing that circulating indicators of cardiovas...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2013.02.012
更新日期：2013-09-10 00:00:00
abstract：:Changes in phasic events in the elderly are reviewed. Such phasic events may in part be determined by the macrostructure of sleep (sleep stages). Therefore, a brief description of sleep architecture and EEG morphology in the aged person is given. Second, there is a marked variability among individuals in the number of...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/0031-9384(93)90095-w
更新日期：1993-10-01 00:00:00
