当前位置： SCI文献检索 > PHYSIOLOGY & BEHAVIOR期刊下所有文献 > Benextramine, a putative neuropeptide Y receptor antagonist, attenuates the termination of receptivity.

Benextramine, a putative neuropeptide Y receptor antagonist, attenuates the termination of receptivity.

Abstract：

:Sexual behavior in female rats is dependent on gonadal steroids. In ovariectomized rats, progesterone treatment typically exerts a biphasic effect on copulatory behavior induced by prior treatment with estradiol. Thus, there is an initial augmentation of the facilitative effect of estradiol occurring 4-10 h after progesterone. This is followed by a profound inhibitory effect, essentially terminating receptivity. We hypothesized that the receptivity terminating effect of progesterone could be due to increased synthesis and release of neuropeptide Y in relevant brain regions. Rats were tested for female sexual behavior 4 h after progesterone (52 h postestradiol). Immediately following this test, benextramine was administered (0, 3, or 15 mg/kg, IP). Subsequently, behavioral tests were administered 24, 48, 72, and 96 h postbenextramine. Benextramine treatment attenuated the inhibitory effects of progesterone on receptivity (lordosis quotients and percent of responding animals) without affecting either proceptive or rejection behaviors. These data suggest that blockade of NPY (and alpha-adrenergic) receptors is associated with selective enhancements of specific components of sexual behavior in female rats. Specifically, blockade of NPY receptors by benextramine is associated with continued receptivity.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Clark JT

doi

10.1016/0031-9384(92)90378-f

subject

Has Abstract

pub_date

1992-11-01 00:00:00

pages

965-9

issue

5

eissn

0031-9384

issn

1873-507X

pii

0031-9384(92)90378-F

journal_volume

52

pub_type

杂志文章

相关文献

PHYSIOLOGY & BEHAVIOR文献大全
  • Gastric compliance in bulimia nervosa.

    abstract：:Bulimia nervosa (BN) is a psychiatric illness characterized by eating binges followed by inappropriate behavioral attempts to compensate for the binges, usually vomiting or laxative abuse. Patients with BN have disturbances in the development of satiety during a meal as well as disturbances in functions of the upper g...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2005.11.010

    authors： Zimmerli EJ,Walsh BT,Guss JL,Devlin MJ,Kissileff HR

    更新日期：2006-02-28 00:00:00

  • Mood and appetite: Their relationship with discretionary and total daily energy intake.

    abstract：BACKGROUND:Negative affect is shown consistently to promote unhealthy food choices and dietary intake in laboratory studies. However, this relationship in naturalistic settings is less clear and previous research is limited by dietary assessment methodology and neglects to account for several important moderating varia...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2019.05.011

    authors： Fong M,Li A,Hill AJ,Cunich M,Skilton MR,Madigan CD,Caterson ID

    更新日期：2019-08-01 00:00:00

  • Sexual experience blocks the ability of clitoral stimulation to induce a conditioned place preference in the rat.

    abstract：:We have previously established the rewarding value of clitoral stimulation (CLS) through the demonstration that manual, distributed, CLS induces a significant conditioned place preference (CPP) and conditioned partner preference in naïve, hormonally primed and non-hormonally primed rats. The present experiment asks wh...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2013.06.005

    authors： Parada M,Jafari N,Pfaus JG

    更新日期：2013-07-02 00:00:00

  • Naloxone-sensitive potentiation at granule cell synapses in the ventral dentate gyrus and stress ulcers.

    abstract：:Continuous perfusion of the granule cells in the ventral dentate gyrus with naloxone blocked the long-term potentiation (LTP) induced by high-frequency electrical stimulation of the posterolateral amygdala in freely-moving rats. This treatment also aggravated the stomach ulceration produced by cold restraint. LTP, on ...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(92)90121-h

    authors： Henke PG

    更新日期：1992-04-01 00:00:00

  • Reliability of event-related potentials: the influence of number of trials and electrodes.

    abstract：:The reliability of event-related potentials (ERPs) is an important factor determining the value of studies relating ERP components to individual differences. However, studies examining the reliability of ERPs are surprisingly scarce. The current study examines the test-retest reliability of ERP components (VPP, N170, ...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2014.03.008

    authors： Huffmeijer R,Bakermans-Kranenburg MJ,Alink LR,van Ijzendoorn MH

    更新日期：2014-05-10 00:00:00

  • Promoting children's healthy eating in obesogenic environments: Lessons learned from the rat.

    abstract：:Current statistics on children's eating patterns and obesity rates are consistent with the idea that genetic taste predispositions, traditional feeding practices, and the obesogenic environment combine to increase the likelihood of unhealthy outcomes in many individuals. In this paper, we focus on one particular level...

    journal_title：Physiology & behavior

    pub_type： 杂志文章,评审

    doi：10.1016/j.physbeh.2011.05.017

    authors： Birch LL,Anzman-Frasca S

    更新日期：2011-09-26 00:00:00

  • Fluoxetine prevents the development of depressive-like behavior in a mouse model of cancer related fatigue.

    abstract：:Cancer patients frequently suffer from fatigue, a complex syndrome associated with tiredness and depressed mood. Cancer-related fatigue (CRF) can be present at the time of diagnosis, escalates during treatment, and can persist for years after treatment. CRF negatively influences quality of life, limits functional inde...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2014.12.045

    authors： Norden DM,Devine R,Bicer S,Jing R,Reiser PJ,Wold LE,Godbout JP,McCarthy DO

    更新日期：2015-03-01 00:00:00

  • Water adulteration with citric acid: effects on drinking and responsivity to regulatory challenges.

    abstract：:Rats with permanent access to a water supply adulterated with citric acid (CA) displayed persistent reductions in fluid intake and fluid/food ratios; and at appropriate concentrations of CA, they also exhibited lowered body weights and drinking deficits after fluid deprivation and after hypertonic NaCl injections. Unl...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(86)90025-9

    authors： Watson PJ,Beatey S,Wagner F,Stahl T

    更新日期：1986-01-01 00:00:00

  • Effects of intracerebroventricular injection of dynorphin, leumorphin and alpha neo-endorphin on operant feeding in pigs.

    abstract：:Young pigs, which are useful experimental animals for biomedical research, were prepared with lateral intracerebroventricular (ICV) cannulae and housed individually in cages fitted with operant panels, with food and water ad lib. ICV injection of 200 micrograms of dynorphin A 1-17 or 1-13 resulted in a significant mea...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(90)90233-t

    authors： Baldwin BA,de la Riva C,Ebenezer IS

    更新日期：1990-12-01 00:00:00

  • Influences of feeding and drinking on circadian rhythms of opioid peptides in plasma, hypothalamus and pituitary gland in rats.

    abstract：:Changes of plasma, hypothalamic and pituitary immunoreactive beta-endorphin (IR-beta-end), methionine-enkephalin (IR-Met-enk) and ACTH (IR-ACTH) were studied under various conditions of feeding and watering in rats. When rats were fed from 17:00 to 09:00 hr and water was given ad lib, plasma IR-beta-end and IR-ACTH ha...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(86)90294-5

    authors： Takahashi H,Motomatsu T,Nawata H,Kato K,Ibayashi H,Nobunaga M

    更新日期：1986-01-01 00:00:00

  • Diphenyl diselenide ameliorates monosodium glutamate induced anxiety-like behavior in rats by modulating hippocampal BDNF-Akt pathway and uptake of GABA and serotonin neurotransmitters.

    abstract：UNLABELLED:Monosodium glutamate (MSG), a flavor enhancer used in food, administered to neonatal rats causes neuronal lesions and leads to anxiety when adulthood. AIMS:We investigated the anxiolytic-like effect of diphenyl diselenide (PhSe)2 and its mechanisms on anxiety induced by MSG. MAIN METHODS:Neonatal male and ...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2015.11.038

    authors： Rosa SG,Quines CB,Stangherlin EC,Nogueira CW

    更新日期：2016-03-01 00:00:00

  • Annual rhythm and hormonal control of predatory behavior in female ferrets.

    abstract：:The predatory behavior of female ferrets shows seasonal fluctuations which appear to be affected by estradiol. Under natural lighting conditions in the laboratory the annual rhythm of the behavior was observed during anestrus, estrus, pregnancy, pseudopregnancy and lactating period. Females in heat failed to show pred...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(86)90287-8

    authors： Harrer S,Schmidt WJ

    更新日期：1986-01-01 00:00:00

  • Taste cells in the gut and on the tongue. Their common, paraneuronal features.

    abstract：:Chemoreception of foodstuff in the gut is performed by endocrine cells dispersed in the gut epithelium. They are bipolar cells extending an apical process to the gut lumen and releasing their messenger substances from the cell base in response to the apical stimuli. The cells share cell-biological features with neuron...

    journal_title：Physiology & behavior

    pub_type： 杂志文章,评审

    doi：10.1016/0031-9384(91)90198-w

    authors： Fujita T

    更新日期：1991-05-01 00:00:00

  • Preproenkephalin mRNA levels are regulated by acute stress and estrogen stimulation.

    abstract：:Enkephalins facilitate female reproductive behavior. Within the limbic system and hypothalamus, estrogen induced the expression of preproenkephalin (PPE) mRNA. Estrogen injection caused a biphasic increase in the PPE mRNA levels within the ventromedial hypothalamic nucleus and posterodorsal medial amygdala. The first ...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/s0031-9384(99)00261-9

    authors： Sinchak K,Eckersell C,Quezada V,Norell A,Micevych P

    更新日期：2000-06-01 00:00:00

  • Sleep on a high heat capacity mattress increases conductive body heat loss and slow wave sleep.

    abstract：:Environmental temperature can strongly affect sleep. The habitual sleep phase is usually located between evening decline and morning rise of the circadian rhythm of core body temperature (CBT). However, the thermophysiological mechanisms promoting or disturbing sleep are not yet fully understood. The purpose of this s...

    journal_title：Physiology & behavior

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.physbeh.2017.12.014

    authors： Kräuchi K,Fattori E,Giordano A,Falbo M,Iadarola A,Aglì F,Tribolo A,Mutani R,Cicolin A

    更新日期：2018-03-01 00:00:00

  • Effects of different types of isocaloric parenteral nutrients on food intake and metabolic concomitants.

    abstract：:Whether spontaneous food intake (SFI) is controlled by infused nutrient type or its caloric content, irrespective of nutrient type, was investigated. Rats were infused for 4 days with isocaloric solutions of different nutrient type but sharing the same intermediary metabolic oxidative pathway, providing 25% of daily c...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(95)00028-h

    authors： Bodoky G,Meguid MM,Yang ZJ,Laviano A

    更新日期：1995-07-01 00:00:00

  • Coping facilitated troponin T increases and hypo-responsivity in the copeptin-HPA-axis during acute mental stress in a black cohort: The SABPA study.

    abstract：BACKGROUND:Defensive coping (DefS) was associated with a vulnerable cardiovascular profile in blacks. The copeptin/vasopressin system is a manifestation of hypothalamic-pituitary-adrenal-axis activity and may act as an acute compensatory mechanism when there is a disruption in volume-loading homeostasis, i.e. when card...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2019.05.012

    authors： Myburgh CE,Malan L,Möller M,Magnusson M,Melander O,Rauch HGL,Steyn F,Malan NT

    更新日期：2019-08-01 00:00:00

  • Intermittent access to sweet high-fat liquid induces increased palatability and motivation to consume in a rat model of binge consumption.

    abstract：:Binge eating disorders are characterized by discrete episodes of rapid and excessive food consumption. In rats, giving intermittent access to sweet fat food mimics this aspect of binge eating. These models typically employ solid food; however, the total amount consumed depends on motivation, palatability and satiety, ...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2013.03.005

    authors： Lardeux S,Kim JJ,Nicola SM

    更新日期：2013-04-10 00:00:00

  • Activity rhythm degrades after strenuous exercise in chronic fatigue syndrome.

    abstract：:Post-exertional exacerbation of symptoms is one of the major characteristics of chronic fatigue syndrome (CFS). In this study, we evaluated the hypothesis that disturbances in circadian chronobiological regulation may play a role in generating this phenomenon. We recorded physical activity for 6-day periods in 16 wome...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/s0031-9384(02)00808-9

    authors： Ohashi K,Yamamoto Y,Natelson BH

    更新日期：2002-09-01 00:00:00

  • Potentiation of panic-like behaviors of the rat by subconvulsive doses of strychnine.

    abstract：:The present study was carried out to determine possible panicogenic effects of strychnine administered in subconvulsive doses to rats. Two experiments were conducted to assess two major features of panic in animal models: panic-related flight (through the observation of wild running [WR]) and defensive fights. In the ...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2003.10.003

    authors： de Paula HM,Hoshino K

    更新日期：2004-01-01 00:00:00

  • Sexual experience of male rats influences anxiety-like behavior and androgen levels.

    abstract：:There is a wide body of literature to suggest that sexual experience may influence androgen secretion in various species, in turn, androgens may also influence anxiety. We hypothesized that sexual experience may alter anxiety behavior and secretion of endogenous androgens. Experiment 1: anxiety behavior of rats with a...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2007.04.018

    authors： Edinger KL,Frye CA

    更新日期：2007-10-22 00:00:00

  • Decreased dominance in a limited access test but normal maternal behavior in micrencephalic rats.

    abstract：:Micrencephalic offspring produced by gestational treatment with the antimitotic compound/methylazoxymethanol acetate (MAM) are remarkable for substantial preservation of function concurrent with severe neural stunting. Altered behaviors in these micrencephalics, including light shyness and response perseveration, are ...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(95)00154-b

    authors： Ferguson SA,Arrowood JW,Schultetus RS,Holson RR

    更新日期：1995-11-01 00:00:00

  • Validity and reliability of Polar® RS800CX heart rate monitor, measuring heart rate in dogs during standing position and at trot on a treadmill.

    abstract：UNLABELLED:The aim of the present study was to assess criterion validity, and relative and absolute reliability of Polar® RS800CX heart rate monitor, compared to simultaneously recorded electrocardiogram (ECG) data, in measuring heart rate of dogs during standing position and at trot on a treadmill. METHODS:Heart beat...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2013.03.002

    authors： Essner A,Sjöström R,Ahlgren E,Lindmark B

    更新日期：2013-04-10 00:00:00

  • Conditioned taste aversion dependent regulation of amygdala gene expression.

    abstract：:The present experiments investigated gene expression in the amygdala following contingent taste/LiCl treatment that supports development of conditioned taste aversion (CTA). The use of whole genome chips and stringent data set filtering led to the identification of 168 genes regulated by CTA compared to non-contingent...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2011.11.001

    authors： Panguluri SK,Kuwabara N,Kang Y,Cooper N,Lundy RF

    更新日期：2012-02-28 00:00:00

  • Different ontogenetic patterns of testosterone production reflect divergent male reproductive strategies in chimpanzees and bonobos.

    abstract：:Male reproductive effort is often strongly related to levels of the steroid hormone testosterone. However, little research has examined whether levels of testosterone throughout development might be tied to individual or species differences in the reproductive strategies pursued by adult males. Here, we tested the hyp...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2013.03.003

    authors： Wobber V,Hare B,Lipson S,Wrangham R,Ellison P

    更新日期：2013-05-27 00:00:00

  • Effects of prenatal testosterone propionate treatment on saccharin preference of adult rats exposed to ethanol in utero.

    abstract：:Prenatal exposure to alcohol feminizes saccharin consumption patterns in adult male rats. To study the involvement of testosterone in this effect, testosterone propionate (TP) was administered to pregnant dams in an attempt to reverse that feminized saccharin consumption pattern in the male offspring. Female offspring...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(87)90016-3

    authors： McGivern RF,Holcomb C,Poland RE

    更新日期：1987-01-01 00:00:00

  • Dual 24-hour feeding response to 2DG in rats: daytime increase and nighttime decrease.

    abstract：:Thirty-six rats were injected IP with 2DG (0, 250, or 500 mg/kg) at 7-day intervals, once at light onset (7 a.m.) and once at dark onset (7 p.m.), and postinjection food intake was monitored for 24 hours. Five hundred mg/kg 2DG caused food intake to rise above control levels during the first 6 hours of daylight, regar...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(89)90179-0

    authors： Thompson CI,Fleming RL,Franken KA,Hornback DA,Boha SP

    更新日期：1989-01-01 00:00:00

  • Aversive viscerally referred states and thirst accompanying the sating of hunger motivation by rapid digestion of glucosaccharides.

    abstract：:Associative conditioning of satiety indicates that concentrated maltodextrin (cMD) may induce a mildly aversive visceral signal within 20 min of its ingestion, as well as satiating normally. Individuals' awareness of this adverse state was tested on ratings of statistically distinct descriptions of factors liable to s...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2010.11.027

    authors： Booth DA,O'Leary G,Li L,Higgs S

    更新日期：2011-03-01 00:00:00

  • Partner preference: assessing the role of the female goat.

    abstract：:For domestic ruminants, the male is thought to have the control over mate choice. The aim of this study was to assess the potential role the female goat plays in choosing a sexual partner. Approach frequency and proximity time to various social or sexual stimuli in a Y-maze apparatus were used as partner preference as...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/j.physbeh.2010.01.022

    authors： Margiasso ME,Longpre KM,Katz LS

    更新日期：2010-04-19 00:00:00

  • Design and performance of an accurate demand feeder for the study of feeding behaviour in sea bass, Dicentrarchus labrax L.

    abstract：:A new demand feeder was designed for the automatic and accurate feeding of fish. The feeding device is microcomputer controlled and permits the continuous recording of feeding behaviour. The electromechanical feeder consists of a sliding door powered by a solenoid which provides only one weighed pellet when activated ...

    journal_title：Physiology & behavior

    pub_type： 杂志文章

    doi：10.1016/0031-9384(94)90244-5

    authors： Sánchez-Vázquez FJ,Martínez M,Zamora S,Madrid JA

    更新日期：1994-10-01 00:00:00