Taste cells in the gut and on the tongue. Their common, paraneuronal features.

Abstract:

:Chemoreception of foodstuff in the gut is performed by endocrine cells dispersed in the gut epithelium. They are bipolar cells extending an apical process to the gut lumen and releasing their messenger substances from the cell base in response to the apical stimuli. The cells share cell-biological features with neurons and are classified as paraneurons. Noteworthy, the gut paraneurons do not seem to be stimulated by monosodium glutamate (MSG) as our dog experiment indicates. Administration of 50 mM MSG into the duodenal loop of anesthetized dogs did not cause changes in the volume and protein output in the pancreatic juice. The gustatory cells in the taste bud show essentially the same structure and function as the gut endocrine cells. A single gustatory cell type (type III) seems to receive different chemical stimuli, whereas different endocrine cell types in the gut react to different stimuli. The gustatory cells possess numerous peptidergic-type granules besides synapse-associated small clear vesicles. The former granules, in the guinea pig and dog, are abundant in the cytoplasm, giving an endocrine-like appearance to the cell. Peptidic signal substances contained in the granules remain to be identified. Comparison of the gustatory cells in the taste bud with the endocrine cells in the gut and with other paraneurons may put into front certain hitherto unexplored structures and functions of the cells.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Fujita T

doi

10.1016/0031-9384(91)90198-w

subject

Has Abstract

pub_date

1991-05-01 00:00:00

pages

883-5

issue

5

eissn

0031-9384

issn

1873-507X

pii

0031-9384(91)90198-W

journal_volume

49

pub_type

杂志文章,评审
  • Effects of opiate antagonists on feeding and spontaneous locomotion in deer.

    abstract::The effects of opioid antagonists on seasonal changes in feeding behavior of white-tailed deer (Odocoileus virginianus) during fall, winter, and summer, as well as in bottle-fed fawns are described. Naltrexone had no effect on the amount of milk ingested by bottle-fed fawns. After weaning naltrexone significantly decr...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(85)90267-7

    authors: Plotka ED,Morley JE,Levine AS,Seal US

    更新日期:1985-12-01 00:00:00

  • Opiate antagonists and copulatory behavior of male hamsters.

    abstract::A possible role of endogenous opioids in male copulatory behavior was examined in six experiments which studied the effects of opiate antagonists on the copulatory behavior of male hamsters (Mesocricetus auratus). In Experiment 1, the acute administration of naloxone hydrochloride (4 mg/kg, SC) ten minutes before test...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(86)90048-x

    authors: Wu FM,Noble RG

    更新日期:1986-01-01 00:00:00

  • Dehydroepiandrosterone and exercise in golden hamsters.

    abstract::Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) are adrenal androgens that have been associated with a sense of well-being in humans. We describe two experiments done to test the hypothesis that an increase in DHEA or DHEAS secretion is associated with the inclination to exercise using a hamst...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(99)00108-0

    authors: Pieper DR,Lobocki CA,Lichten EM,Malaczynski J

    更新日期:1999-10-01 00:00:00

  • Brain catalase activity is highly correlated with ethanol-induced locomotor activity in mice.

    abstract::It has been demonstrated that acute administration of lead to mice enhances brain catalase activity and ethanol-induced locomotion. These effects of lead seem to be related, since they show similar time courses and occur at similar doses. In the present study, in an attempt to further evaluate the relation between bra...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(01)00511-x

    authors: Correa M,Sanchis-Segura C,Aragon CM

    更新日期:2001-07-01 00:00:00

  • Assessment of behavioral determinants influencing success of supervised exercise therapy in patients with intermittent claudication: A cross sectional survey.

    abstract:BACKGROUND:Supervised exercise therapy is the first step in treatment of intermittent claudication. However, adherence to supervised exercise therapy is low. Limited access and reimbursement issues are known reasons, though lack of motivation is often leading. Behavioral determinants influencing motivation and thus adh...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2019.112732

    authors: Bolt LJJ,Jacobs MLYE,Sigterman TA,Krasznai AG,Sikkink CJJM,Schurink GWH,Bouwman LH

    更新日期:2020-03-01 00:00:00

  • Odor detection performance in hypothyroid and euthyroid rats.

    abstract::The influence of hypothyroidism on the odor detection ability of male Long-Evans rats was determined using high-precision olfactometry and a go/no-go operant task. Nonparametric signal detection measures of sensitivity and responsitivity, as well as measures of S+ response latency, the number of aborted trials, and se...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(95)00145-x

    authors: Brosvic GM,Risser JM,Mackay-Sim A,Doty RL

    更新日期:1996-01-01 00:00:00

  • The role of prolactin and testosterone in mediating seasonal differences in the self-grooming behavior of male meadow voles, Microtus pennsylvanicus.

    abstract::Self-grooming in response to the odors of conspecifics is a form of olfactory communication among meadow voles. The amount of time meadow voles spend self-grooming when they encounter the odors of conspecifics varies seasonally, with males targeting the odors of reproductively active females only during the breeding s...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2005.05.011

    authors: Leonard ST,Alizadeh-Naderi R,Stokes K,Ferkin MH

    更新日期:2005-07-21 00:00:00

  • Social stress enhances IL-1beta and TNF-alpha production by Porphyromonas gingivalis lipopolysaccharide-stimulated CD11b+ cells.

    abstract::Psychological stress is associated with an increased expression of markers of peripheral inflammation, and there is a growing literature describing a link between periodontal pathogens and systemic inflammation. The hypothesis of the present work is that exposing mice to the social stressor, called social disruption (...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2009.06.013

    authors: Bailey MT,Kinsey SG,Padgett DA,Sheridan JF,Leblebicioglu B

    更新日期:2009-09-07 00:00:00

  • Conditioned aversion to a taste perceived while grooming.

    abstract::Four experiments were conducted to determine how the characteristics of conditioned taste aversion (CTA), as described from studies conducted in the drinking and feeding contexts, applied in the grooming context. In Experiment 1, sodium saccharin was mixed with a "neutral-tasting" jelly and applied to the fur of male ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(82)90057-9

    authors: Reidinger RF Jr,Beauchamp GK,Barth M

    更新日期:1982-04-01 00:00:00

  • Effects of hypothalamic knife cuts on the ingestive responses to glucose and insulin.

    abstract::Parasagittal knife cuts through the perifornical hypothalamus either medial or lateral to the fornix produced hyperphagia and obesity and altered the rat's ingestive responses to dilute glucose solutions. The lateral knife cut rats drank less dilute glucose solution under both nondeprived and food deprived conditions ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(75)90280-2

    authors: Sclafani A,Gale SK,Springer D

    更新日期:1975-07-01 00:00:00

  • Alpha 2-adrenoceptor antagonists and male sexual behavior: II. Erectile and ejaculatory reflexes.

    abstract::Three alpha 2-adrenoceptor antagonists, yohimbine, idazoxan, and imiloxan, all shown to have stimulatory effects on sexual arousal/motivation, were studied to identify their possible effects on the other two major components of male copulatory behavior: erection and ejaculation. Genital reflex ex copula tests were use...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(87)90124-7

    authors: Smith ER,Lee RL,Schnur SL,Davidson JM

    更新日期:1987-01-01 00:00:00

  • Could a deficiency in growth hormone signaling be beneficial to the aging brain?

    abstract::Several studies have shown that growth hormone (GH)-deficient/resistant animals have a prolonged lifespan compared with their normal siblings. Studies in our laboratory have suggested that both Ames dwarf and GH receptor/GH binding protein knockout (GH-R-KO) mice do not experience age-induced cognitive aging at the sa...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2003.10.018

    authors: Kinney-Forshee BA,Kinney NE,Steger RW,Bartke A

    更新日期:2004-02-01 00:00:00

  • Mechanisms for AgRP neuron-mediated regulation of appetitive behaviors in rodents.

    abstract::The obesity epidemic is a major health and economic burden facing both developed and developing countries worldwide. Interrogation of the central and peripheral mechanisms regulating ingestive behaviors have primarily focused on food intake, and in the process uncovered a detailed neuroanatomical framework controlling...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,评审

    doi:10.1016/j.physbeh.2017.10.006

    authors: Thomas MA,Xue B

    更新日期:2018-06-01 00:00:00

  • Early trauma and adult obesity: is psychological dysfunction the mediating mechanism?

    abstract::Several studies have shown that physical and/or sexual abuse during childhood may lead to the development of obesity later in life. Despite these consistent findings, the mechanism for the increased risk of obesity following developmental trauma is unknown. It has been suggested that psychological dysfunction, includi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2009.08.010

    authors: D'Argenio A,Mazzi C,Pecchioli L,Di Lorenzo G,Siracusano A,Troisi A

    更新日期:2009-12-07 00:00:00

  • Aggression in female mice: contrasting effects of amiflamine (FLA 336), a selective and reversible MAO-type A inhibitor.

    abstract::The effects of FLA 336 on the attack by resident groups of female mice on strange female intruders were assessed. This MAO-type A inhibitor clearly suppressed attack in treated subjects without producing major alterations in other activities but there was no clear dose-response relationship. The substance also increas...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(93)90132-y

    authors: Wallian L,Brain PF,Haug M

    更新日期:1993-08-01 00:00:00

  • Relative hedonic value modulates anticipatory contrast.

    abstract::Intake of an initial substance (e.g., 0.15% saccharin) is suppressed when the presentation of this substance precedes the availability of a preferred solution (e.g., 32% sucrose) in brief daily pairings. The present experiments show that degree of this anticipatory contrast effect is related to the relative hedonic va...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(94)90386-7

    authors: Flaherty CF,Turovsky J,Krauss KL

    更新日期:1994-06-01 00:00:00

  • Quality and intensity of binary odor mixtures.

    abstract::The perceived intensity and quality of binary mixtures consisting of the common but dissimilar odorants, benzaldehyde (almond), eugenol (cloves), propionic acid (vinegar) and (-)-carvone (spearmint), were determined over a wide range of environmentally relevant concentrations. Consistent data were obtained from each o...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(84)90118-5

    authors: Laing DG,Panhuber H,Willcox ME,Pittman EA

    更新日期:1984-08-01 00:00:00

  • Effect of load carriage and natural terrain conditions on cognitive performance in desert environments.

    abstract:BACKGROUND:Correct decision making is a critical component of cognitive performance of a soldier, which may be influenced by the load carriage and terrain conditions during their deployment in desert environment. PURPOSE:The present study was aimed to investigate the effects of loads and terrain conditions on the cogn...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2017.06.014

    authors: Bhattacharyya D,Pal M,Chatterjee T,Majumdar D

    更新日期:2017-10-01 00:00:00

  • Hippocampal conditioned responses in the absence of entorhinal input.

    abstract::Hippocampal unit responses to conditioned stimuli were analyzed in intact rats and in rats deprived of the input from the entorhinal cortex to the hippocampus. Cells in normal rats responded more intensely to a conditioned stimulus when it was applied within 1 min from a previous one. The rats with lesions had smaller...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(75)90108-0

    authors: Segal M

    更新日期:1975-09-01 00:00:00

  • Bitter-responsive brainstem neurons: characteristics and functions.

    abstract::The sensation that humans describe as "bitter" is evoked by a large group of chemically diverse ligands. Bitter stimuli are avoided by a range of species and elicit reflex rejection, behaviors considered adaptations to the toxicity of many of these compounds. We review novel evidence for neurons that are narrowly tune...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2009.02.042

    authors: Travers SP,Geran LC

    更新日期:2009-07-14 00:00:00

  • Effects of attention and rewarded activity on immune parameters and wound healing in pigs.

    abstract::Challenging animals with a demanding situation they are able to cope with and where they are rewarded may be a source of positive emotions and possibly of increased welfare. In order to test if this results in changes of immunological parameters and wound healing, 56 pigs (7-20 weeks of age), housed in groups of 8 ani...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2006.07.001

    authors: Ernst K,Tuchscherer M,Kanitz E,Puppe B,Manteuffel G

    更新日期:2006-10-30 00:00:00

  • The role of adrenocorticotropin and norepinephrine in appetitive learning in the rat.

    abstract::This study examines the involvement of ACTH/4-10 and norepinephrine during training and testing of a complex maze task. Hormones were administered post-trial to eliminate effects on processes other than learning and memory during training and testing sessions. ACTH/4-10, but not NE, facilitates acquisition of an appet...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(83)90015-x

    authors: O'Reilly HM,Coleman GJ,Ng KT

    更新日期:1983-02-01 00:00:00

  • The "novelty response" in an electric fish: response properties and habituation.

    abstract::The electromotor behavior evoked by novel sensory stimuli in the electrogenic teleost fish Gnathonemus petersii was examined. Novelty responses (NRs) consisted of a transient accelerations of the rate of electric organ discharges following a change in sensory input. NRs were basically similar in nontreated and in immo...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(99)00153-5

    authors: Post N,von der Emde G

    更新日期:1999-12-01 00:00:00

  • Responses to basic taste qualities in rats selectively bred for high versus low saccharin intake.

    abstract::Rats selectively bred for relatively high (HiS) and relatively low (LoS) saccharin intake were offered sweet (sucrose), bitter (quinine, sucrose octaacetate), salty (sodium chloride), starchy (Polycose((R))), and sour (citric acid) solutions at several concentrations; sucrose/quinine, and sucrose/citric acid mixtures ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(99)00246-2

    authors: Dess NK

    更新日期:2000-05-01 00:00:00

  • Olfactory bulbectomy in rats modulates feeding pattern but not total food intake.

    abstract::The role of olfactory input in the regulation of food intake and feeding patterns in rats was investigated by performing bilateral olfactory bulbectomy. Compared to control rats, bulbectomized rats ate the same amounts of food, but did so via a decrease in meal size, and a doubling in meal number. Although no increase...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(93)90238-b

    authors: Meguid MM,Gleason JR,Yang ZJ

    更新日期:1993-09-01 00:00:00

  • Enhancement of opioid-mediated analgesia by ingestion of amniotic fluid: onset latency and duration.

    abstract::Ingestion of placenta and amniotic fluid has been shown to enhance opioid-mediated analgesia produced by morphine injection, footshock, vaginal/cervical stimulation, and during late pregnancy in rats. The present study was designed to determine how soon after ingestion the enhancement begins and how long it lasts. Tai...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(89)90058-9

    authors: Doerr JC,Kristal MB

    更新日期:1989-11-01 00:00:00

  • A selective serotonin reuptake inhibitor reduces REM sleep in the homing pigeon.

    abstract::Avian and mammalian 'rapid eye movement' sleep (REM sleep) resemble each other in several aspects. However, the question of whether REM sleep has a shared evolutionary ancestry in birds and mammals has yet to be thoroughly explored. The brain regions and neurotransmitter systems involved in the generation of mammalian...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2005.12.003

    authors: Fuchs T,Siegel JJ,Burgdorf J,Bingman VP

    更新日期:2006-03-30 00:00:00

  • Chronic administration of phosphatidylserine during ontogeny enhances subject-environment interactions and radial maze performance in C57BL/6 mice.

    abstract::A longitudinal behavioral study was performed in mice exposed to the bovine brain phospholipid phosphatidylserine (BC-PS) from birth until sixty days. Examination of treated and control pups revealed no effect of the treatment on body weight nor on sensorimotor reflexes. At one and two months of age, when placed in an...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(90)90090-q

    authors: Ammassari-Teule M,Fagioli S,Maritati M,Populin R,Pavone F

    更新日期:1990-04-01 00:00:00

  • Comparison between the central effects of CRH and AVP in steers.

    abstract::In cattle, the in vivo effects of centrally administered corticotropin-releasing hormone (CRH) or arginine vasopressin (AVP) from the perspective of stress regulation have not been fully elucidated. We compared behavioral, adrenocorticotropic, and autonomic nervous responses to intracerebroventricularly infused bCRH o...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2007.10.014

    authors: Yayou K,Sato Y,Ito S,Nakamura M

    更新日期:2008-02-27 00:00:00

  • Spices and energy balance.

    abstract::The sensory properties of foods and beverages are primary determinants of food choice. Some flavor components have an inherent hedonic valence that influences ingestive behavior. However, these hedonic impressions may be modified and others newly formed through their association with the post-ingestive consequences of...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2011.10.028

    authors: Mattes RD

    更新日期:2012-11-05 00:00:00