Odor detection performance in hypothyroid and euthyroid rats.

Abstract:

:The influence of hypothyroidism on the odor detection ability of male Long-Evans rats was determined using high-precision olfactometry and a go/no-go operant task. Nonparametric signal detection measures of sensitivity and responsitivity, as well as measures of S+ response latency, the number of aborted trials, and session time were obtained in daily 200-trial test sessions prior to, during, and after 50 days of maintenance on 0.1% propylthiouracil (PTU). Similar determinations were made in control animals. Neither odor detection nor associated nonsensory performance measures were influenced by hypothyroidism. These results suggest that PTU-induced hypothyroidism does not affect the odor detection performance of rats.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Brosvic GM,Risser JM,Mackay-Sim A,Doty RL

doi

10.1016/0031-9384(95)00145-x

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

117-21

issue

1

eissn

0031-9384

issn

1873-507X

pii

003193849500145X

journal_volume

59

pub_type

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