REM sleep deprivation affects extinction of cued but not contextual fear conditioning.

Abstract:

:Previous research has demonstrated that rapid eye movement (REM), or paradoxical, sleep deprivation can interfere with the retention of certain types of learning tasks, particularly spatial learning. The present study investigated the effects of 6 h of REM sleep deprivation on the retention and extinction of both cued and contextual conditioning tasks in rats. Sleep-deprived animals showed normal retention of both types of conditioning tasks but retarded extinction of the cued task and a trend toward attenuated spontaneous recovery of the contextual task. The results provide further evidence for the involvement of REM sleep in learning and memory processes.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Silvestri AJ

doi

10.1016/j.physbeh.2004.11.011

subject

Has Abstract

pub_date

2005-03-16 00:00:00

pages

343-9

issue

3

eissn

0031-9384

issn

1873-507X

pii

S0031-9384(05)00005-3

journal_volume

84

pub_type

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