Abstract：
:Prenatal exposure to alcohol feminizes saccharin consumption patterns in adult male rats. To study the involvement of testosterone in this effect, testosterone propionate (TP) was administered to pregnant dams in an attempt to reverse that feminized saccharin consumption pattern in the male offspring. Female offspring were also studied to determine the effect of TP on saccharin preference in normal males and females. During the last week of gestation, dams were administered a liquid diet containing 35% ethanol derived calories, an isocaloric liquid diet containing no ethanol, or Purina Lab Chow. Half of the dams in each group received twice daily injections of TP, the other half were injected with the oil vehicle. Saccharin consumption of adult fetal alcohol exposed (FAE) males from dams administered oil or TP was significantly greater than controls, indicating that the feminized pattern of saccharin consumption of FAE males cannot be overcome with TP administration during the prenatal period. In controls, prenatal TP exposure alone was found to increase adult saccharin consumption in both sexes. Prenatal administration of TP was also found to markedly depress body weight of offspring of dams receiving the liquid diets compared to offspring from dams receiving the same diets plus oil injections. Body weights of offspring from TP or oil injected dams receiving the chow fed diets during pregnancy did not differ.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
McGivern RF,Holcomb C,Poland REdoi
10.1016/0031-9384(87)90016-3subject
Has Abstractpub_date
1987-01-01 00:00:00pages
241-6issue
2eissn
0031-9384issn
1873-507Xpii
0031-9384(87)90016-3journal_volume
39pub_type
杂志文章abstract：:Cardiovascular responses to moderate steady-state exercise were studied in Type A and Type B males and females. Eighteen men and 17 women, ages 20 to 40 years, were chosen for Type A (males = 10, females = 10) and Type B (males = 8, females = 7) groups by means of the Jenkins Activity Survey (JAS). Subjects exercised ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(96)00214-4
更新日期：1996-10-01 00:00:00
abstract：:Suckling rats were undernourished from birth by underfeeding their mothers. They were refed from 3 weeks of age. Detailed analyses were made of the walking locomotion of previously undernourished and well-fed control female rats at 10 weeks, using electronic, computer, and TV techniques. Previously undernourished rats...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90421-w
更新日期：1992-10-01 00:00:00
abstract：:Rats were chronically maintained on an ethanol liquid diet for 16 days. Three weeks after cessation of ethanol intake, animals were tested for the acquisition of shuttle box avoidance and the retention of passive avoidance behaviour. Alcohol consuming rats showed a significant impairment of acquisition in the shuttle ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(85)90099-x
更新日期：1985-02-01 00:00:00
abstract：:To investigate brain substrates of spatial memory, neuronal expression of c-Fos protein was studied. Two groups of rats were trained in two spatial memory tasks in the Morris water maze, where the rats have to apply a reference memory rule or a working memory rule. In addition to the experimental groups, two control g...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(03)00060-x
更新日期：2003-04-01 00:00:00
abstract：:The food intakes of male and female rats (Harvard strain) adapted to cold (5 degrees C) starting at weaning were studied in the cold and during reacclimation to 25 degrees C. Following 24 hr food deprivation, the male rats regained the weight they had lost without making up for the food they had missed (increased food...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90377-8
更新日期：1982-07-01 00:00:00
abstract：:Minimal hepatic encephalopathy (MHE), which represents the early stage of this condition, is not clinically apparent and is prevalent in up to 80% of patients. The poor outcomes of MHE encouraged us to identify more simple methods for early diagnosis of MHE. To this purpose, we evaluated the contemporary manifestation...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2017.01.033
更新日期：2017-05-01 00:00:00
abstract：:Olfactory bulbectomy (OBX) is a well known screening model for depression. Panax quinquefolium (PQ) is known for its therapeutic potential against several psychiatric disorders. Nitric oxide (NO), an intercellular messenger has been suggested to play a crucial role in the pathogenesis of depression. The present study ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.02.037
更新日期：2014-04-22 00:00:00
abstract：:Studies reported recently have shown that tumor necrosis factor-alpha (TNF-alpha) a cytokine released by macrophages and monocytes plays a key role in inflammatory processes and immune and neuro-endocrine regulation. TNF-alpha is also produced in the central nervous system (CNS). However, the role of this cytokine in ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00514-3
更新日期：1998-02-15 00:00:00
abstract：:Level of food restriction was manipulated in mice to assess its importance for the acquisition and expression of a conditioned odor discrimination. In training, animals were exposed to odors (either rose or lemon) presented on a piece of filter paper in a pot covered in bedding. For half of the conditioning trials, gr...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(00)00439-x
更新日期：2001-03-01 00:00:00
abstract：:There is a considerable literature on the neurobiology of reward, based largely on studies of addiction or substance abuse. This review considers the possibility that the neural circuits that mediate reward evolved for ethologically relevant cues, such as social attachment. Specifically, mesocorticolimbic dopamine app...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/s0031-9384(03)00148-3
更新日期：2003-08-01 00:00:00
abstract：:The ability to utilize oxygen has been shown to affect a wide variety of physiological factors often considered beneficial for survival. As the ability to learn can be seen as one of the core factors of survival in mammals, we studied whether selective breeding for endurance running, an indication of aerobic capacity,...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2012.01.011
更新日期：2012-05-15 00:00:00
abstract：:Hydrogen sulfide (H2S) is an endogenous neuromodulator produced mainly by the enzyme cystathionine gamma-lyase (CSE) in peripheral tissues. A pronociceptive role of endogenously produced H2S has been previously reported by our group in a model of orofacial inflammatory pain. Using the established persistent orofacial ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2018.02.007
更新日期：2018-05-01 00:00:00
abstract：:Physical restraint, like many other stressors, can block early pregnancy, but the underlying physiological mechanisms have not been established. Exogenous estrogens in minute doses will also block early pregnancy. In the present study, female rats were exposed to 5 h of restraint daily for the first 5 days after insem...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90446-9
更新日期：1992-07-01 00:00:00
abstract：:Although the habenula occupies a potentially important link between forebrain and midbrain, lesion of the complex produces little effect in most standard behavioral paradigms. More recently, it has been shown that such lesions may impair the ability to initiate or switch responses appropriate to environmental continge...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(91)90324-h
更新日期：1991-04-01 00:00:00
abstract：:Rats' voluntary ethanol intake varies with dispositional factors and energy status. The joint influences of these were of interest here. We previously reported that rats selectively bred for high voluntary saccharin intake (HiS) consume more ethanol and express more robust conditioning of preference for flavors paired...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2012.12.001
更新日期：2013-01-17 00:00:00
abstract：:The effects of chronic estrogen withdrawal and subsequent hormone replacement on the feeding and body weight of adult lean and genetically obese Zucker rats were investigated. Following confirmation of a delay in the vaginal canalization of the fatty rat, subgroups of each genotype received either ovariectomy or sham ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(79)90130-6
更新日期：1979-07-01 00:00:00
abstract：:The long-term consequences of a single social defeat on open field behaviour in rats were studied, with special emphasis on the time course of stress-induced changes. Animals were subjected to social defeat by placing them into the territory of an aggressive male conspecific for 1 h. After the defeat session experimen...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(95)02271-6
更新日期：1996-07-01 00:00:00
abstract：:Hypohydration is generally considered to have a negative effect on cognitive function, despite several studies reporting comparable findings between hydration states. Recommendations to avoid moderate dehydration (≥ 2% loss in body mass) are commonly made to athletes, on the provision that this deficit may impair opti...
journal_title：Physiology & behavior
pub_type： 杂志文章,meta分析
doi：10.1016/j.physbeh.2019.03.008
更新日期：2019-05-15 00:00:00
abstract：:Analyses of 4-8 Hz electrical activity (RSA) of the mid-ventral hippocampus, motor activity (M), and blood pressure were carried out during experiments in which three monkeys were operantly conditioned to slow heart rate (HR), to speed HR or during control, no feedback (FB) periods. The results showed that RSA activit...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90047-6
更新日期：1982-04-01 00:00:00
abstract：:The aim of the present study was to test the hypothesis that vesicular glutamate transporter 3 (VGluT3) deficiency is associated with cognitive impairments. Male VGluT3 knockout (KO) and wild type (WT) mice were exposed to a behavioral test battery covering paradigms based on spontaneous exploratory behavior and reinf...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.112688
更新日期：2019-12-01 00:00:00
abstract：:Rats housed in social isolation postweaning (isolates) show profound behavioral and neurobiological differences when compared to socially housed rats (socials). Fischer rats (F344) relative to Lewis rats are hyperresponsive and significantly more susceptible to stressful stimuli. This investigation tested the hypothes...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(99)00193-6
更新日期：2000-01-01 00:00:00
abstract：:By using the two-bottle, self-selection method it was found that an excess of thyroid hormone administration to rats increased water and sodium intake. Thyroidectomy changed the initial preference from water to sodium chloride. Oral treatment of the thyroidectomized rats with thyroid hormones brought salt ingestion ba...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(88)90231-4
更新日期：1988-01-01 00:00:00
abstract：:The startle behaviour of the fetus (both spontaneous and elicited) was examined in fetuses of mothers who drank alcohol and mothers who did not. Fetuses exposed to alcohol showed a higher frequency of spontaneous startles and were less likely to exhibit a normal startle in response to a vibroacoustic stimulus. These d...
journal_title：Physiology & behavior
pub_type： 临床试验,杂志文章
doi：10.1016/s0031-9384(02)00804-1
更新日期：2002-08-01 00:00:00
abstract：BACKGROUND:Defensive coping (DefS) was associated with a vulnerable cardiovascular profile in blacks. The copeptin/vasopressin system is a manifestation of hypothalamic-pituitary-adrenal-axis activity and may act as an acute compensatory mechanism when there is a disruption in volume-loading homeostasis, i.e. when card...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.05.012
更新日期：2019-08-01 00:00:00
abstract：:We have shown that vagotomy (VGX) attenuates the reduction of meal size (MS) produced by cholecystokinin (CCK) -8 and -33 and that celiaco-mesenteric ganglionectomy (CMGX) attenuates the prolongation of the intermeal interval (IMI) produced by CCK-33. Here, we report the following novel data. First, by determining the...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2011.10.018
更新日期：2012-02-01 00:00:00
abstract：:Effects of maternal separation on feeding behavior, particularly on rebound hyperphagia, in adult rats were examined. Time-restricted scheduled feeding (2 h per day for 6 days), was given at the age of 3, 6, 9 or 12 weeks in rats that were maternal separated from postnatal days (PD) 1-21 and control rats. Following th...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(00)00305-x
更新日期：2000-09-15 00:00:00
abstract：:Play fighting is a behavior exhibited by juveniles of many mammalian species, but the neurology of this behavior is poorly understood. In the present study lesions of the septal area or control operations were performed in rats at 23 days of age and social play was studied between the ages of 27-41 days of age. Septal...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90046-4
更新日期：1982-04-01 00:00:00
abstract：:Mixtures of compounds can often be tasted even when all of their components are too weak to be tasted separately. Such mixtures are said to be integrative. Integration was demonstrated by mixing compounds in concentrations proportional to their separate detection thresholds and then measuring the detection threshold o...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00270-9
更新日期：1997-11-01 00:00:00
abstract：:Three different techniques were used to study the effects of 72 hr deprivation of paradoxical sleep on percentages total sleep, light slow wave sleep, deep slow wave sleep and paradoxical sleep during deprivation and recovery periods in rats. The paradoxical sleep deprivation methods used were the classical platform, ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(86)90341-0
更新日期：1986-01-01 00:00:00
abstract：:A possible role of endogenous opioids in male copulatory behavior was examined in six experiments which studied the effects of opiate antagonists on the copulatory behavior of male hamsters (Mesocricetus auratus). In Experiment 1, the acute administration of naloxone hydrochloride (4 mg/kg, SC) ten minutes before test...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(86)90048-x
更新日期：1986-01-01 00:00:00
