Abstract：
:Binge eating disorders are characterized by discrete episodes of rapid and excessive food consumption. In rats, giving intermittent access to sweet fat food mimics this aspect of binge eating. These models typically employ solid food; however, the total amount consumed depends on motivation, palatability and satiety, which are difficult to dissociate with solid food. In contrast, lick microstructure analysis can be used to dissociate these parameters when the ingestant is a liquid. Therefore, we developed a binge model using a liquid emulsion composed of corn oil, heavy cream and sugar. We show that rats given intermittent access to this high-fat emulsion develop binge-like behavior comparable to that previously observed with solid high-fat food. One feature of this behavior was a gradual escalation in consumption across 2.5 weeks of intermittent access, which was not apparent in rats given lower-fat liquid on the same access schedule. Lick microstructure analysis suggests that this escalation was due at least in part to increases in both motivation to consume and palatability-driven consumption.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Lardeux S,Kim JJ,Nicola SMdoi
10.1016/j.physbeh.2013.03.005subject
Has Abstractpub_date
2013-04-10 00:00:00pages
21-31eissn
0031-9384issn
1873-507Xpii
S0031-9384(13)00055-3journal_volume
114-115pub_type
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更新日期：1977-07-01 00:00:00
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更新日期：1991-09-01 00:00:00
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更新日期：2014-08-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.physbeh.2004.10.022
更新日期：2005-01-31 00:00:00
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pub_type： 杂志文章
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更新日期：2001-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：2020-12-01 00:00:00
abstract：PURPOSE:To describe and evaluate behavioral models of binge-type eating. DATA IDENTIFICATION:Studies were identified using Medline and hand searches of bibliographies of identified articles. STUDY SELECTION:Isomorphic studies were selected that were judged to have some measure of construct validity. DATA EXTRACTION:...
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pub_type： 杂志文章,评审
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更新日期：2004-08-01 00:00:00
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更新日期：2012-05-15 00:00:00
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pub_type： 杂志文章,评审
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pub_type： 杂志文章
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journal_title：Physiology & behavior
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1987-01-01 00:00:00
abstract：:The effect of amylin injected IP on food intake in rats of different age (7-9 weeks, 3 months, 15-18 months) was investigated. The possible site of amylin action was investigated using vagotomized rats. Lastly, the influence of food composition on amylin's effect was investigated. In 12-h food-deprived old rats, food ...
journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1994-05-01 00:00:00
