Conditioned taste aversion to saccharin induced by 2, 4, 5-trichlorophenoxyacetic acid in albino rats.

Abstract:

:Four groups of Wistar rats were exposed either to saccharin + 2,4,5-T (taste-aversion group, T-A), saccharin + oil vehicle (taste-aversion control, T-A C), water + 2,4,5-T (enhanced neophobia, E-N), or water + oil (neophobia, N). Rats in the T-A group evidenced a marked aversion to saccharin in 3 consecutive preference tests, performed every third day, starting 3 days after exposure. The aversion was less pronounced, although statistically significant in 2 additional preference tests, performed respectively after a 9-day rest period of ad lib water drinking, and a 24 hr period of forced exposure to saccharin. An enhanced neophobia effect was found in the E-N group in the first preference test. Suggestions are made concerning the possible long-term effects on food preferences among wild-living animals as a result of large-scale application of 2,4,5-T-containing herbicides.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Sjödén PO,Archer T

doi

10.1016/0031-9384(77)90174-3

subject

Has Abstract

pub_date

1977-07-01 00:00:00

pages

159-61

issue

1

eissn

0031-9384

issn

1873-507X

pii

0031-9384(77)90174-3

journal_volume

19

pub_type

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