Abstract:
:Previous studies that examined the effects of knife cuts ventral to the septal area, or the pattern of anterograde degeneration after other obesity-inducing lesions or cuts, have implicated the septal area in feeding behavior. However, lesion studies have been inconsistent. In the present study, large electrolytic lesions that destroyed all or nearly all of the septal area resulted in excessive weight gain in female rats (25 g/20 days compared to 1 g/20 days for controls). Lesions confined to the ventral septum produced equal weight gains, but rats with lesions confined to the dorsal septum did not differ from controls. The excessive weight gains were accompanied by modest hyperphagia. The weight gains were not the result of incidental damage to adjacent structures such as the stria terminalis or the shell of the nucleus accumbens. It is concluded that the ventral portion of the septum is part of a limbic-hypothalamic circuitry regulating food intake in female rats.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Pankey EA,Shurley MR,King BMdoi
10.1016/j.physbeh.2007.07.019subject
Has Abstractpub_date
2008-01-28 00:00:00pages
8-12issue
1-2eissn
0031-9384issn
1873-507Xpii
S0031-9384(07)00355-1journal_volume
93pub_type
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journal_title:Physiology & behavior
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journal_title:Physiology & behavior
pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2015-12-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2001-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/0031-9384(86)90159-9
更新日期:1986-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/s0031-9384(99)00167-5
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journal_title:Physiology & behavior
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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更新日期:2001-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:1996-01-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章,随机对照试验
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更新日期:2018-07-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2007.03.012
更新日期:2007-06-08 00:00:00
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pub_type: 杂志文章
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更新日期:1995-03-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
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journal_title:Physiology & behavior
pub_type: 杂志文章
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更新日期:2014-06-22 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
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更新日期:1992-04-01 00:00:00