Abstract：
:Food intake and gastric emptying were measured simultaneously after cholecystokinin-octapeptide (CCK-8) and saline infusions in order to test the hypothesis that reduction in gastric emptying mediates the effect of CCK-8 on food intake. Each of twelve nonobese healthy men received intravenous infusions of CCK-8 and saline on separate nonconsecutive days after they had consumed 500 g of tomato soup tagged with technetium-99-DTPA. Intake of a test meal was measured 20 min after consumption of the soup while gastric emptying was simultaneously monitored by gamma emission scintigraphy of the soup. Food intake and gastric emptying of the soup were both significantly reduced by CCK-8 infusions in comparison to saline. There was a significant correlation between the amount of the test meal eaten and the amount of soup emptied during the period the test meal was being eaten, but not before the meal, only on days when CCK-8 was infused. Differences in intakes between days when saline was infused and days when CCK-8 was infused did not correlate with differences in gastric emptying of soup. These results suggest that CCK may amplify signals of satiety in proportion to the fullness of the stomach. Gastric emptying per se may not mediate the effects of CCK-8 on food intake.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Muurahainen N,Kissileff HR,Derogatis AJ,Pi-Sunyer FXdoi
10.1016/0031-9384(88)90330-7subject
Has Abstractpub_date
1988-01-01 00:00:00pages
645-9issue
4-5eissn
0031-9384issn
1873-507Xpii
0031-9384(88)90330-7journal_volume
44pub_type
杂志文章abstract：:Vitamin D has been shown in a wide variety of species to play critical roles in neurodevelopment. Vitamin D deficiency disrupts development of the brain and can cause lasting behavioral dysfunction. Zebrafish have become an important model for the study of development in general and neurodevelopment in particular. Zeb...
journal_title：Physiology & behavior
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更新日期：2020-10-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2006.03.035
更新日期：2006-07-30 00:00:00
abstract：:Restoration of memory by pretest reminder treatments following ECS-induced amnesia in principle could be mediated by nonassociative arousal and/or reactivation of information by the reminder stimuli. In the present research, arousal value of the reminder treatment was largely a function of the novelty of the context i...
journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1985-08-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(86)90261-1
更新日期：1986-01-01 00:00:00
abstract：:A longitudinal behavioral study was performed in mice exposed to the bovine brain phospholipid phosphatidylserine (BC-PS) from birth until sixty days. Examination of treated and control pups revealed no effect of the treatment on body weight nor on sensorimotor reflexes. At one and two months of age, when placed in an...
journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：1990-04-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
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更新日期：2018-10-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(89)90245-x
更新日期：1989-08-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(77)90166-4
更新日期：1977-07-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2009.09.012
更新日期：2009-12-07 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2005.08.057
更新日期：2005-12-15 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(02)00912-5
更新日期：2002-12-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(85)90099-x
更新日期：1985-02-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2016.11.010
更新日期：2017-02-01 00:00:00
abstract：:Triacylglycerols of varying chain lengths were tested for their effects on food intake in fasted Single-Comb White Leghorn cockerels 9-12 weeks of age. Tributyrin, tricaprylin, triolein, or saline were intubated intragastrically or infused intrahepatically. All triacylglycerol administrations were in 10 ml volumes wit...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90300-q
更新日期：1992-06-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(93)90374-o
更新日期：1993-06-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(00)00370-x
更新日期：2001-01-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2017.03.038
更新日期：2017-07-01 00:00:00
abstract：:The goal of this study was to investigate possible relationships between different aspects of behavioural decline in aged (17 months) NMRI mice by a multivariate analysis. These mice presented defects in spatial processing both in place learning in a Morris-type water maze and in spontaneous alternation in a Y-maze, a...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(93)90120-5
更新日期：1993-08-01 00:00:00
abstract：:Ingestion of placenta and amniotic fluid has been shown to enhance opioid-mediated analgesia produced by morphine injection, footshock, vaginal/cervical stimulation, and during late pregnancy in rats. The present study was designed to determine how soon after ingestion the enhancement begins and how long it lasts. Tai...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(89)90058-9
更新日期：1989-11-01 00:00:00
abstract：:Air righting results in an animal turning over when it is dropped from a height in an inverted position. In the rat, air righting is a complex set of movements that depends only on an intact labyrinth and the normal vestibular input. Visual modulation of air righting does not develop until adulthood; and the ability t...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(00)00208-0
更新日期：2000-06-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(96)00250-8
更新日期：1996-11-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.01.015
更新日期：2014-09-01 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(98)00077-8
更新日期：1998-06-15 00:00:00
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journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(95)00078-w
更新日期：1995-09-01 00:00:00
abstract：:Parents, and particularly mothers, can influence their offspring's development in non-genetic ways. Maternal effects can occur during the mothering phase as well as during the embryonic phase. Prenatal maternal effects in birds can be mediated by yolk steroid hormones that influence subsequent offspring development. S...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2011.08.009
更新日期：2012-01-18 00:00:00
abstract：:There is strong evidence from animal studies that prenatal stress has different effects on male and female offspring. In general, although not always, prenatal stress increases anxiety, depression and stress responses, both hypothalamic-pituitary-adrenal and cardiovascular, in female offspring rather than in male. Mal...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2012.02.011
更新日期：2012-07-16 00:00:00
abstract：:Pine voles (Microtus pinetorum) were given sipper tubes containing saccharin solution, and after drinking, were injected with 0.15 M LiCl. Subsequently, two-sipper tests were given to assure the presence of conditioned flavor avoidance (CFA), and then animals were presented with saccharin in carboxymethyl-cellulose on...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(85)90269-0
更新日期：1985-12-01 00:00:00
abstract：:Young-adult, female Binghamton Heterogeneous Stock (HET) mice either were exposed to lead via drinking water from birth, or not. Eight days after giving birth to their first litter of pups (at about 70-75 days of age), postpartum aggression tests were conducted. Unfamiliar Het male intruders were introduced to the pri...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(89)90053-x
更新日期：1989-11-01 00:00:00
abstract：:This study examined the behavioral responses of near-term rat fetuses to a range of chemosensory fluids that resemble constituents of milk or are present in the context of suckling immediately after birth. Milk and dimethyl disulfide (DMDS), a constituent of pup saliva that promotes postnatal nipple attachment, were e...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90411-t
更新日期：1992-10-01 00:00:00
abstract：:A short-term fluid-intake test is described which is directed at the study of individual variation in gustation in laboratory mice. To avoid position preferences associated with two-bottle tests, single graduated cylinders are used to present the solution. Intake of water and solutions is recorded for a 6-h period beg...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(98)00016-x
更新日期：1998-04-01 00:00:00
