Abstract：
:The effects of daily single injections of 20 mg/kg cocaine on locomotor activity, core temperature, and heart rate were determined by radiotelemetry. There was a progressive increase in locomotor activity over the 30-day treatment period. Cocaine-induced activity was 9-12-fold greater than that of saline-treated animals. Cocaine also caused increases in core temperature and heart rate. Tolerance did not develop to the locomotor, hyperthermic, and tachycardic responses resulting from repeated cocaine administration. Comparison of the time-course of the cocaine-induced responses revealed that, on Day 1 and 3, the peak locomotor activity was observed 15 min after cocaine administration, whereas the hyperthermic response peaked at 95 min on those days. The fact that the peak locomotor activity and the hyperthermic response occurred at different times suggests that different processes acting independently or interacting may be involved in these actions of cocaine.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Ansah TA,Wade LH,Shockley DCdoi
10.1016/s0031-9384(96)00250-8subject
Has Abstractpub_date
1996-11-01 00:00:00pages
1261-7issue
5eissn
0031-9384issn
1873-507Xpii
S0031938496002508journal_volume
60pub_type
杂志文章abstract：:Adapting behavior to dynamic stimulus-reward contingences is a core feature of reversal learning and a capacity thought to be critical to socio-emotional behavior. Impairment in reversal learning has been linked to multiple psychiatric outcomes, including depression, Parkinson's disorder, and substance abuse. A recent...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2016.03.034
更新日期：2016-07-01 00:00:00
abstract：:The renin-angiotensin system (RAS) is functional within adipose tissue and angiotensin II, the active component of RAS, has been implicated in adipose tissue hypertrophy and insulin resistance. In this study, captopril, an angiotensin converting enzyme (ACE) inhibitor that prevents angiotensin II formation, was used t...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2009.05.009
更新日期：2009-08-04 00:00:00
abstract：:Roux-en-Y gastric bypass (RYGB) surgery might modify the gut microbiota composition differently in the three distinct anatomical sections of the small intestine compared to sham surgery. We showed that RYGB induced changes in the microbiota of the alimentary limb and the common channel resembling those seen after preb...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2013.06.008
更新日期：2013-07-02 00:00:00
abstract：:Vitamin D has been shown in a wide variety of species to play critical roles in neurodevelopment. Vitamin D deficiency disrupts development of the brain and can cause lasting behavioral dysfunction. Zebrafish have become an important model for the study of development in general and neurodevelopment in particular. Zeb...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2020.113016
更新日期：2020-10-01 00:00:00
abstract：:Groups of intact male and female Wistar rats were exposed to a standard passive avoidance procedure. The intensity of the light bulb illuminating the platform during adaptation, pre- and post-shock trials was manipulated (5, 25 or 75 W). Entrance latencies during pre-shock trials were longer for males than for females...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(86)90084-3
更新日期：1986-01-01 00:00:00
abstract：:The activity of antioxidant enzymes was investigated in red blood cells of male and female Wistar rats 3-4 months of age. Superoxide dismutase (EC 1.15.1.1), catalase (EC 1.11.1.6), and glutathione peroxidase (EC 1.11.1.9) did not show any significant variation in the different phases of the estrous cycle. No differen...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(94)00234-v
更新日期：1995-02-01 00:00:00
abstract：:Visual information processing was investigated in the inferotemporal cortical (ITCx)-amygdalar (AM)-lateral hypothalamic (LHA) axis which contributes to food-nonfood discrimination. Neuronal activity was recorded from monkey AM and LHA during discrimination of sensory stimuli including sight of food or nonfood. The ta...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(89)90149-2
更新日期：1989-02-01 00:00:00
abstract：:Prolonged consumption of ketogenic diets (KD) has reported neuroprotective benefits. Several studies suggest KD interventions could be useful in the management of neurological and developmental disorders. Alterations in the Engrailed (En) genes, specifically Engrailed 2 (En2), have neurodevelopmental consequences and ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2016.04.001
更新日期：2016-07-01 00:00:00
abstract：:It has been recognized for some time that a number of different neuropeptides exert powerful effects on food intake. During the last few years, the neurocircuitry within which these peptides operate has also begun to be elucidated. Peptidergic feeding-regulatory neurones are found both in the hypothalamus and the brai...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/s0031-9384(01)00611-4
更新日期：2001-11-01 00:00:00
abstract：:The purpose of the present study was to investigate the effects of a high-fat diet (HFD) in previously trained rats that have been detrained for different periods. Two groups of female rats were, first, either treadmill trained for 8 weeks or remained sedentary (Sed). Trained animals, thereafter, remained inactive for...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2007.03.012
更新日期：2007-06-08 00:00:00
abstract：:Cardiovascular responses to moderate steady-state exercise were studied in Type A and Type B males and females. Eighteen men and 17 women, ages 20 to 40 years, were chosen for Type A (males = 10, females = 10) and Type B (males = 8, females = 7) groups by means of the Jenkins Activity Survey (JAS). Subjects exercised ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(96)00214-4
更新日期：1996-10-01 00:00:00
abstract：:The reward comparison hypothesis suggests that drugs of abuse-induced conditioned saccharin suppression intake is due to the reward value of drugs of abuse that outweighs that of a saccharin solution dissociating from the aversive LiCl-induced conditioned taste aversion (CTA). Huang and Hsiao (2008) provided some conf...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2015.07.022
更新日期：2015-11-01 00:00:00
abstract：:Hypothyroidal rats produced by low iodine diet or propylthiouracyl (PTU) were less active in the open field and received fewer food reinforcements than controls in a lever press situation at both 22 degrees C and 1 degree C. The hypothyroid rats also pressed less when heat was the reinforcer. On the other hand, hypert...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(87)90140-5
更新日期：1987-01-01 00:00:00
abstract：:Rats living in a laboratory foraging paradigm began each meal by bar pressing to procure access to food and then could eat any amount. In different conditions the procurement price changed from low (10 bar presses) to high (200 or 400 bar presses) every ten days, five days, or one day, or on schedules of one-day-low/t...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(94)00194-a
更新日期：1995-01-01 00:00:00
abstract：:Obesity is a world-wide problem, and a risk factor for cardiovascular disease, diabetes, cancer and other diseases. It is well established that sex differences influence fat storage. Males and females exhibit differences in anatomical fat distribution, utilization of fat stores, levels of adipose tissue-derived hormon...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2017.02.040
更新日期：2017-07-01 00:00:00
abstract：:Many socially relevant odors are detected in rodent species by the vomeronasal organ and subsequently processed by the accessory olfactory system (AOS). We previously found that gonadectomized male and female rats treated in adulthood with testosterone propionate (TP) showed equivalent Fos responses in the AOS to odor...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(01)00674-6
更新日期：2002-03-01 00:00:00
abstract：:In Experiment 1, an SC injection of 14 micrograms CRH greatly suppressed the vocalizing of isolated guinea pig pups 1 h later and produced highly elevated plasma cortisol levels. In Experiment 2, SC injection of 18 international units of ACTH produced similar cortisol elevations, but had a negligible effect on vocaliz...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(91)90492-7
更新日期：1991-07-01 00:00:00
abstract：:Lactic acid in arterial blood, systolic and diastolic blood pressures, and heart rates of baboons were examined for three naive subjects, and for five experimental subjects during baseline conditions and during training to elevate diastolic blood pressure through operant conditioning methodology. Lactic acid and cardi...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(82)90235-9
更新日期：1982-10-01 00:00:00
abstract：:Sleep is an important factor in relation to accidents, long-term health and mortality. Our group has had a long-term commitment to research on sleep regulation and its consequences. Over the years we have demonstrated pronounced effects of night work on sleep and alertness, including electroencephalographically determ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2007.05.044
更新日期：2007-09-10 00:00:00
abstract：:Snacking, like any dietary behavior, can be practiced in a manner that is healthful or not. The case presented in this critical review of the literature is that snacking is problematic, primarily due to its contribution to positive energy balance and promotion of overweight/obesity. There is strong evidence that snack...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2018.02.010
更新日期：2018-09-01 00:00:00
abstract：:The relationship between performance in an avoidance conditioning paradigm and the plasma glucose levels of Sprague-Dawley rats was examined in two experiments. In Experiment 1 we investigated whether glucose levels varied with the animal's relative success at acquiring the avoidance task. Results indicated that anima...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90108-e
更新日期：1992-04-01 00:00:00
abstract：UNLABELLED:Acute stress responses of women are typically more reactive than that of men. Women, compared to men, may be more vulnerable to posttraumatic stress disorder (PTSD). Whether there are differences between women and men with PTSD in levels of the stress hormone, cortisol, was investigated in a pilot study. ME...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2009.06.002
更新日期：2010-02-09 00:00:00
abstract：:Winning competitions has been shown to lead to higher testosterone (T) relative to losing in men and males of other species. In Experiment 1, 38 women and 37 men provided a saliva sample, completed a novel computer-based vocabulary competition task at which they won or lost based on their own ability, provided feedbac...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2006.11.017
更新日期：2007-03-16 00:00:00
abstract：:The effect of food texture on the development of schedule-induced polydipsia was examined in six groups of rats (n = 8), each receiving one of six grades of food granulation. A seventh group received pellets. By the end of 15 sessions of FT 60-sec food delivery, rats receiving pellets and the coarser granulations had ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(88)90202-8
更新日期：1988-01-01 00:00:00
abstract：:Sprague-Dawley rats over-consume calories over a 10 week period and develop diet-induced obesity (c. 100 g body weight differential vs controls) when fed a control pellet diet supplemented with chocolate Ensure liquid. Subsequent withdrawal of Ensure immediately reduces caloric intake by more than 50%, and results in ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2014.01.041
更新日期：2014-04-10 00:00:00
abstract：:Dried bonito dashi is often used in Japanese cuisine with a number of documented positive health effects. Its major taste is thought to be umami, elicited by inosine 5'-monophosphate (IMP) and L-amino acids. Previously we found that lactic acid, a major component of dried bonito dashi, enhanced the contribution of man...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2018.11.016
更新日期：2019-02-01 00:00:00
abstract：:Male and female brains have different structures, which can make genders produce various eye- movement patterns. This study presents the results of an eye tracking experiment in which we analyzed the eye movements of 25 male and 20 female participants during passive indoor picture viewing. We examined eye-movement par...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.03.023
更新日期：2019-07-01 00:00:00
abstract：:This study aimed to determine the relative efficacy of the macronutrients, protein, fat and carbohydrate to induce satiation and satiety in rats in relation to macronutrient activation of neurons in the nucleus of the solitary tract (NTS). Male Sprague Dawley rats were schedule-fed twice a day for 2 h, receiving 100% ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.04.022
更新日期：2019-08-01 00:00:00
abstract：:Recent evidence indicates that rats can learn to avoid aversive consequences of several hours of food deprivation by eating more of food having orosensory characteristics that predict a protracted fast. Two new studies tested if macronutrient composition of a flavoured meal before the reinforcing fast influences this ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2006.02.007
更新日期：2006-06-15 00:00:00
abstract：:Appetite and eating are not only controlled by energy needs, but also by extrinsic factors that are not directly related to energy balance. Environmental signals that acquire motivational properties through associative learning-learned cues-can override homeostatic signals and stimulate eating in sated states, or inhi...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2011.04.059
更新日期：2011-09-26 00:00:00
