Abstract:
:It has been recognized for some time that a number of different neuropeptides exert powerful effects on food intake. During the last few years, the neurocircuitry within which these peptides operate has also begun to be elucidated. Peptidergic feeding-regulatory neurones are found both in the hypothalamus and the brainstem, where they act as input stations for hormonal and gastrointestinal information, respectively. These cell populations both project to several other brain regions and interconnect extensively. The present review summarizes the neuroanatomy and connectivity of some prominent peptides involved in food intake control, including neuropeptide Y, melanocortin peptides, agouti gene-related protein, cocaine- and amphetamine-regulated transcript, orexin/hypocretin, melanin-concentrating hormone and cholecystokinin. Disturbances in the hypothalamic neuropeptide systems have been implicated in the phenotype of a genetic model of fatal hypophagia, the mouse anorexia (anx) mutation, which is also discussed.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Broberger C,Hökfelt Tdoi
10.1016/s0031-9384(01)00611-4subject
Has Abstractpub_date
2001-11-01 00:00:00pages
669-82issue
4-5eissn
0031-9384issn
1873-507Xpii
S0031938401006114journal_volume
74pub_type
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journal_title:Physiology & behavior
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pub_type: 杂志文章
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更新日期:1986-01-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2016-12-01 00:00:00
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journal_title:Physiology & behavior
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更新日期:2004-12-15 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90132-l
更新日期:1992-04-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
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更新日期:1982-11-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2006.05.020
更新日期:2006-07-30 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
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更新日期:1995-03-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(95)02119-1
更新日期:1996-04-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2013.06.005
更新日期:2013-07-02 00:00:00
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pub_type: 杂志文章
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更新日期:1998-06-01 00:00:00
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pub_type: 杂志文章
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journal_title:Physiology & behavior
pub_type: 杂志文章
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更新日期:2006-03-30 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
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更新日期:2014-05-10 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
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更新日期:2012-05-15 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(82)90108-1
更新日期:1982-01-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2015.09.019
更新日期:2015-12-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2012.01.013
更新日期:2012-05-15 00:00:00
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journal_title:Physiology & behavior
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1999-08-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(85)90399-3
更新日期:1985-11-01 00:00:00
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journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(97)00478-2
更新日期:1998-02-15 00:00:00