Abstract:
:Roux-en-Y gastric bypass (RYGB) surgery might modify the gut microbiota composition differently in the three distinct anatomical sections of the small intestine compared to sham surgery. We showed that RYGB induced changes in the microbiota of the alimentary limb and the common channel resembling those seen after prebiotic treatment or weight loss by dieting. These changes may be associated with altered production of intestinal hormones known to control energy balance. Postsurgical modulation of gut microbiota may significantly contribute to the beneficial metabolic effects of RYGB surgery.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Osto M,Abegg K,Bueter M,le Roux CW,Cani PD,Lutz TAdoi
10.1016/j.physbeh.2013.06.008subject
Has Abstractpub_date
2013-07-02 00:00:00pages
92-6eissn
0031-9384issn
1873-507Xpii
S0031-9384(13)00194-7journal_volume
119pub_type
杂志文章abstract:BACKGROUND:This cohort study evaluates whether the association between low-grade inflammation and incident depressive symptoms is independent of abdominal obesity and metabolic disturbances. METHODS:A cohort of 1167 non-depressed men aged 35 to 80 years were followed up over 5 years to assess incident depressive sympt...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2014.11.058
更新日期:2015-02-01 00:00:00
abstract::Earlier research has demonstrated that opioid involvement in drinking is primarily mediated centrally [8,10]. Drinking is attenuated by the centrally and peripherally active opioid antagonists naloxone and naltrexone in doses as low as 1.0 mg/kg, but not by the quaternary forms of these antagonists [4]. Peripherally a...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(87)90099-0
更新日期:1987-01-01 00:00:00
abstract::Our prior study showed that the basal blood pressure level and pressor response to peripheral angiotensin II of adult Sprague-Dawley rats were enhanced by perinatal exposure to a high NaCl diet. The purpose of the present study was to assess further the relationship between NaCl-sensitivity of blood pressure and perin...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90164-w
更新日期:1992-03-01 00:00:00
abstract::In order to determine the respective roles of conditioned food aversion, satiety and palatability, we studied behavioral responses to a 50% total milk protein diet, compared with those to a normal protein diet containing 14% total milk protein. Different paradigms were employed, including meal pattern analysis, two-ch...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(02)00977-0
更新日期:2003-02-01 00:00:00
abstract::Female hamsters (Mesocricetus auratus) exposed to a short photoperiod for 8 weeks were ovariectomized, as were hamsters that were maintained in a long photoperiod. We then tested the effect of photoperiod on the ability of progesterone (P) to reduce aggression, as well as on the effects of estrogen (E), alone and with...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90307-n
更新日期:1992-06-01 00:00:00
abstract::Rats exposed to a relatively high dose (7.5 g/kg body weight) of alcohol on either the fifth or tenth postnatal day of age have been reported to have long-lasting deficits in spatial learning ability as tested on the Morris water maze task. The question arises concerning the level of alcohol required to achieve this e...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(97)00424-1
更新日期:1998-01-01 00:00:00
abstract::In this paper we investigated the effect of sex and season on baseline and post-GnRH challenge luteinising hormone (LH) levels in a solitary, seasonally breeding mole-rat. Circulating basal concentrations of luteinising hormone (LH) were found to differ significantly with season in both sexes. However, no significant ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2006.05.020
更新日期:2006-07-30 00:00:00
abstract::The influence of caloric load and nutrient composition on small intestinal satiety was investigated in six dogs with chronic esophageal fistulas. Dogs received small bowel infusion of a mixed nutrient liquid meal, a fat, carbohydrate, and a protein solution over two hours. Each infusion was given over a range of calor...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(97)00107-8
更新日期:1997-07-01 00:00:00
abstract::The present study used the context preexposure facilitation effect (CPFE) to examine long-term retention of incidental context learning in periweanling, adolescent and adult rats. The CPFE is a variant of contextual fear conditioning in which encoding the context representation, associating this representation with sh...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2014.12.033
更新日期:2015-09-01 00:00:00
abstract::Large meals scheduled at greater-than-circadian periods (such as T = 31 h) tend to elicit enhanced activity approximately 24 h subsequent to receipt. These studies characterized the process responsible for this meal-engendered "circadian ensuing activity" (meal CEA). Female Sprague-Dawley rats were housed in stations ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(98)00211-x
更新日期:1999-01-01 00:00:00
abstract::The effects of denervation of fungiform taste buds on preference behavior were studied. Presurgery, 0.01, 0.1, 0.2, and 0.4 M NaCl, and 0.1, 0.2, and 0.4 M KCl were strongly avoided relative to water as measured with 48-h intakes. Bilateral cuts of the chorda tympani nerve (CT) resulted in a decrease in the strength o...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:
更新日期:1996-08-01 00:00:00
abstract::A group (N = 8) of restrained, baroreceptor denervated rats and a sham-operated-control group (n = 8) received discriminated classical conditioning consisting of 30 reinforced trials in which a CS+ was paired with an electric shock US and 30 non-reinforced trials in which a different CS (CS-) was presented alone. The ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(84)90009-x
更新日期:1984-07-01 00:00:00
abstract::Intermittent exposure to the same stressor can lead to a gradual decline in physiological, neuroendocrine and behavioral stress responses (habituation). We investigated possible habituation of cardiac autonomic responsiveness and susceptibility to cardiac arrhythmias in male rats exposed to either intermittent social ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(01)00455-3
更新日期:2001-06-01 00:00:00
abstract::The naturally occurring tendency to compete with other rats for territorial space has been used to study individual behavior characteristics and blood pressure reactivity to social stimuli in adult male TMD-S3 rats. The competitive characteristics of the individual rats are consistent in two different social situation...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(85)90073-3
更新日期:1985-01-01 00:00:00
abstract::Thyroid hormones (TH) are essential for normal development and function of mammalian central nervous system (CNS); TH dysregulation has been implicated in several cognitive and behavioral deficits related to dysfunctions of neurotransmitter systems. In the present study, we investigated the effects of adult onset hypo...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2016.06.016
更新日期:2016-10-01 00:00:00
abstract::Animals were assigned to three experimental groups, conditioned (cyclophosphamide-glucose treatment; C group), non-conditioned (cyclophosphamide-commercial pellet treatment; NC group) and placebo (saline solution-glucose treatment; P group). The three groups were injected intraperitoneally (i.p.) with sheep red blood ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(98)00093-6
更新日期:1998-06-01 00:00:00
abstract::The influence of endogenous opioid peptides (EOPs) on plasma luteinizing hormone (LH) levels in subordinate female highveld mole-rats (Cryptomys hottentotus pretoriae) was investigated to elucidate the physiological mechanisms responsible for inhibiting their gonadotropin-releasing hormone (GnRH) and/or LH release. Th...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2006.02.005
更新日期:2006-05-30 00:00:00
abstract::Searching for food by extensive digging is one of the most important aspects of life of subterranean rodents. We studied the effect of extrinsic (substrate quality) and intrinsic factors (sex and body mass) upon the cost of burrowing, expressed as digging metabolic rate (DMR) in two African mole-rat species (Bathyergi...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2009.10.007
更新日期:2010-01-12 00:00:00
abstract::Naltrexone, a potent opioid antagonist, was given to preweaning rats in order to explore the influence of endogenous opioid systems on organogenesis. Sprague-Dawley rats were injected (SC) daily with either 1 or 50 mg/kg naltrexone to invoke a temporary or complete blockade, respectively, of opioid receptors; animals ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(85)90041-1
更新日期:1985-04-01 00:00:00
abstract::In earlier work, we found that following lipopolysaccharide (LPS) injection at an ambient temperature (Ta) of 23 degrees C, old rats developed blunted fevers compared with those of young rats. However, the old rats did become febrile if placed in a thermally graded alleyway: they spent more time in the warm end of the...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(03)00046-5
更新日期:2003-04-01 00:00:00
abstract::PN200-110 is a recently introduced 1,4-dihydropyridine which has been demonstrated to be a potent calcium channel blocker. 3HPN has been shown to bind in a specific saturable manner to P2 fractions obtained from brain homogenates from male Sprague-Dawley rats. 3HPN binding was found to be temperature-dependent. Specif...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(89)90330-2
更新日期:1989-07-01 00:00:00
abstract::Current study attempted to determine whether repeated smooth pursuit trials using theta motion, in which the directions of retinal image-motion and object-motion are opposed, yield pursuit adaptation. Adaptation trials consisted of 350 step-ramp trials using theta motion, and pre- and post-trials using first-order mot...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2020.113245
更新日期:2021-02-01 00:00:00
abstract::The effects of vomeronasal organ removal (VNX) on male mouse urine marking and aggressive behaviors were investigated. In three different stimulus conditions VNX male marking rates were about half that of sham-operated males. Aggressive behavior was tested by pairing males with male-urine-swabbed castrate males. Only ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(86)90300-8
更新日期:1986-01-01 00:00:00
abstract::The aim of this study was to link parameters describing oral physiology and anatomy of consumers varying in age, gender and ethnicity to food oral processing behavior. Three groups of healthy consumers were compared: Dutch, Caucasian adults (18-30 yrs, n =32), Chinese, Asian adults (18-30 yrs, n =32) and Dutch, Caucas...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2019.112766
更新日期:2020-03-01 00:00:00
abstract::Hippocampal unit responses to conditioned stimuli were analyzed in intact rats and in rats deprived of the input from the entorhinal cortex to the hippocampus. Cells in normal rats responded more intensely to a conditioned stimulus when it was applied within 1 min from a previous one. The rats with lesions had smaller...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(75)90108-0
更新日期:1975-09-01 00:00:00
abstract::The effects of an irreversible long term opioid antagonism on circadian rhythms in body temperature (Tb), locomotor activity (Act) and feeding under normal conditions and following lipopolysaccharide administration (LPS; 2.5 mg/kg) have been investigated in unrestrained mice housed at their thermoneutral zone (30 degr...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(95)00067-s
更新日期:1995-08-01 00:00:00
abstract::The consumption of a large food bolus leads to stomach distension. Gastric distension potently signals the termination of a meal by stimulating gastric mechanoreceptors and activating neuroendocrine circuitry. The ability to terminate a meal is altered in disorders such as bulimia nervosa (BN), binge-eating disorder (...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2011.11.006
更新日期:2012-02-28 00:00:00
abstract:PURPOSE:The aim of this observational study was to identify biomechanical differences, as measured by pharyngeal manometric pressure patterns, between discrete and continuous water swallowing, as well as volitionally initiated and reflexive swallowing. METHODS:Using pharyngeal manometry, swallowing-related pressures f...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2014.12.029
更新日期:2015-03-01 00:00:00
abstract::Evidence suggests that animals are selected to make accurate choices and prioritize goals within the constraints of a given social environment to maximize fitness. These decisions are mostly based on complex processes in which value is linked to reward and cues may carry variable incentive salience. However, the level...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2016.11.028
更新日期:2017-02-01 00:00:00
abstract::Women were divided into those eating at a decelerated or linear rate. Eating rate was then experimentally increased or decreased by asking the women to adapt their rate of eating to curves presented on a computer screen and the effect on food intake and satiety was studied. Decelerated eaters were unable to eat at an ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2008.10.011
更新日期:2009-02-16 00:00:00