Chemesthesis from volatile organic compounds: Psychophysical and neural responses.

Abstract:

:In Experiment 1, subjects sought to localize the nostril stimulated, left or right, in tests with nine esters (acetates, propionates, and butyrates) at concentrations meant to trigger chemesthesis (pungency, irritation). The task produced psychometric functions for chemesthetic detection unconfounded by olfactory sensations. The functions indicated a sharp transition from no detection to perfect detection, rather uniform across the esters, which themselves varied in potency by two log units. The correlation between the thresholds for the eight materials that yielded thresholds and predictions from a published linear free energy relationship (LFER) equaled 0.99. In Experiment 2, amplitude of the negative mucosal potential (NMP) was recorded from the septum. The resulting functions also increased with concentration sharply. Against a criterion amplitude of the NMP, thresholds measured in the first experiment (and predictions from the LFER) correlated 0.99. The NMP seems to offer an adequate objective measure of sensory irritation. The LFER, although effective predictively, could stand to have a parameter to anticipate that molecules beyond a certain size fail to trigger irritation. In the present case, a cut-off of chemesthetic potency occurred between butyl butyrate and hexyl butyrate for the group of subjects, with some variation of the boundary among individuals.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Cain WS,Lee NS,Wise PM,Schmidt R,Ahn BH,Cometto-Muñiz JE,Abraham MH

doi

10.1016/j.physbeh.2006.03.035

subject

Has Abstract

pub_date

2006-07-30 00:00:00

pages

317-24

issue

4-5

eissn

0031-9384

issn

1873-507X

pii

S0031-9384(06)00221-6

journal_volume

88

pub_type

杂志文章
  • Mood and appetite: Their relationship with discretionary and total daily energy intake.

    abstract:BACKGROUND:Negative affect is shown consistently to promote unhealthy food choices and dietary intake in laboratory studies. However, this relationship in naturalistic settings is less clear and previous research is limited by dietary assessment methodology and neglects to account for several important moderating varia...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2019.05.011

    authors: Fong M,Li A,Hill AJ,Cunich M,Skilton MR,Madigan CD,Caterson ID

    更新日期:2019-08-01 00:00:00

  • Salivary IgA secretion rate in young and elderly persons.

    abstract::Immunoglobulin A (IgA) is the dominant immunoglobulin isotype on all mucosal surfaces where it acts as a first line of defense against microbial invasion. Recent investigations suggest that secretory IgA (sIgA) concentrations vary over the day due to a range of variables including dietary factors, daily mood, and exer...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(95)02161-2

    authors: Miletic ID,Schiffman SS,Miletic VD,Sattely-Miller EA

    更新日期:1996-07-01 00:00:00

  • Beta-endorphin-like immunoreactivity levels in the hypothalamus, the periaqueductal grey and the pituitary of the DBA mouse: determination by ELISA and relationship to nociception.

    abstract::The present paper describes the development and application of an enzyme-linked immunosorbent assay (ELISA) for the assessment of beta-endorphin-like immunoreactivity (beta-ELIR) level in the hypothalamus, the periaqueductal grey (PAG) and the pituitary of DBA/2 mice that were subjected to mild social stress (aggressi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(89)90315-6

    authors: Külling P,Siegfried B,Frischknecht HR,Messiha FS,Pasi A

    更新日期:1989-07-01 00:00:00

  • Behavioral and physiological responses to stocking density in sea bream (Sparus aurata): Do coping styles matter?

    abstract::Stocking density is considered a stress factor for fish and is therefore one of the numerous concerns about fish welfare in an aquaculture context. Stress coping styles (SCS) are defined as a coherent set of individual physiological and behavioral differences in stress responses that are consistent across time and con...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2019.112698

    authors: Carbonara P,Alfonso S,Zupa W,Manfrin A,Fiocchi E,Pretto T,Spedicato MT,Lembo G

    更新日期:2019-12-01 00:00:00

  • Inert gas narcosis disrupts encoding but not retrieval of long term memory.

    abstract::Exposure to increased ambient pressure causes inert gas narcosis of which one symptom is long-term memory (LTM) impairment. Narcosis is posited to impair LTM by disrupting information encoding, retrieval (self-guided search), or both. The effect of narcosis on the encoding and retrieval of LTM was investigated by test...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2015.02.043

    authors: Hobbs M,Kneller W

    更新日期:2015-05-15 00:00:00

  • Maze performance in rats with hippocampal perforant paths lesions: some aspects of functional recovery.

    abstract::The performance of two experimental groups--one with lesions of the perforant paths projecting to the dorsal hippocampus (the D group) and one with lesions of the perforant paths to both the dorsal and ventral hippocampus (the DV group)--was compared with the performance of a lesioned control group and an intact contr...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(75)90210-3

    authors: Myhrer T

    更新日期:1975-10-01 00:00:00

  • Mate choice could be random in female rats (Rattus norvegicus).

    abstract::Female mate choice is often investigated in terms of reproductive success in order to understand how male characteristics contribute to sexual attractiveness. Previous studies have found that females rats prefer mating with their first encounter rather than males visited subsequently, suggesting that the rewarding val...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2017.10.031

    authors: Le Moëne O,Snoeren EM

    更新日期:2018-02-01 00:00:00

  • Early weaning predisposes rats to exacerbated activity-stress ulcer formation.

    abstract::Rats were weaned early (Day 15), normally (Day 21) or late (Day 27). When they reached 200 g (+/- 10) they were placed into the activity-stress paradigm. Half the rats in each weaning group were housed in activity-wheel cages and fed only 1 hr each day. The remaining rats served as food-yoked home cage controls and we...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(85)90012-5

    authors: Glavin GB,Pare WP

    更新日期:1985-06-01 00:00:00

  • Effects of substantia nigra stimulation on hypothalamic rage reaction in cats.

    abstract::The effects of substantia nigra (SN) (pars compacta) stimulation on the rage reaction elicited by ventromedial hypothalamic nucleus (VMH) were investigated in the cat. The studied parameters of the rage reaction were: the current and the frequency threshold for the appearance of the hissing and the hissing latency. A ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(86)90395-1

    authors: Crescimanno G,Piazza P,Benigno A,Amato G

    更新日期:1986-01-01 00:00:00

  • Blood pressure and heart rate reactivity to mental strain in adolescent judo athletes.

    abstract::This exploratory investigation examined the association between maximal aerobic power (VO2max) and blood pressure (BP) and heart rate (HR) reactivity to mental challenge. Adolescent male judo athletes (n = 20) performed a 2-min mental arithmetic. Heart rate was recorded before, during, and after the arithmetic, and BP...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(94)90187-2

    authors: Szabó A,Péronnet F,Frenkl R,Farkas A,Petrekanits M,Mészáros J,Hetényi A,Szabó T

    更新日期:1994-08-01 00:00:00

  • Thermal comfort following immersion.

    abstract::Unlike thermal comfort in air, little research has been undertaken exploring thermal comfort around water sports. We investigated the impact of swimming and cooling in air after swimming on thermal comfort. After 10 min of swimming-and-resting cycles in 28°C water, volunteers wearing two types of garments or in swim b...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2014.12.016

    authors: Guéritée J,Redortier B,House JR,Tipton MJ

    更新日期:2015-02-01 00:00:00

  • Effects of drinks sweetened with sucrose or aspartame on hunger, thirst and food intake in men.

    abstract::Forty-two nondieting adult males were given 8 or 16 oz of lemonade, sweetened to equal intensity with either aspartame or sucrose, or the same volumes of water, or no drink. Subjects were separated into three groups receiving the drinks at different times: with a self-selection lunch, or 30, or 60 min before lunch. Fo...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(90)90254-2

    authors: Rolls BJ,Kim S,Fedoroff IC

    更新日期:1990-07-01 00:00:00

  • Fluoxetine-maintained obese humans: effect on food intake and body weight.

    abstract::The effects of fluoxetine on food intake, body weight, and mood of obese individuals was examined in a 16-week inpatient/outpatient study. Six male and eight female obese volunteers began the study (four male and five females completed all phases of the study). They lived in a residential laboratory during three one-w...

    journal_title:Physiology & behavior

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0031-9384(99)00020-7

    authors: Ward AS,Comer SD,Haney M,Fischman MW,Foltin RW

    更新日期:1999-07-01 00:00:00

  • Female mice seek refuge from castrated males, but not intact or vasectomized males, mitigating a socially-induced glucocorticoid response.

    abstract::Sexual conflict may be manifested during social interactions, shaping the costs of reproduction in sexually reproducing species. This conflict, and the physical necessity of intromission, can intensify the already costly nature of reproduction for female mammals. To identify and partition the costs that males inflict ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2019.112678

    authors: Gale TJ,Garratt M,Brooks RC

    更新日期:2019-11-01 00:00:00

  • Delta-9-tetrahydrocannabinol and cannabidiol, but not ondansetron, interfere with conditioned retching reactions elicited by a lithium-paired context in Suncus murinus: An animal model of anticipatory nausea and vomiting.

    abstract::Chemotherapy patients report not only acute nausea and vomiting during the treatment itself, but also report anticipatory nausea and vomiting upon re-exposure to the cues associated with the treatment. We present a model of anticipatory nausea based on the emetic reactions of the Suncus murinus (musk shrew). Following...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2005.08.045

    authors: Parker LA,Kwiatkowska M,Mechoulam R

    更新日期:2006-01-30 00:00:00

  • Plasma corticosterone levels during repeated presentation of two intensities of restraint stress: chronic stress and habituation.

    abstract::This study measured plasma corticosterone levels in male rats during repeated daily presentations of two intensities of restraint stress. The corticosterone response to a stress session was defined as the change from pre-stress levels to levels after 60 minutes of restraint. With the relatively intense stress imposed ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(88)90097-2

    authors: Pitman DL,Ottenweller JE,Natelson BH

    更新日期:1988-01-01 00:00:00

  • Blood glucose levels in portal and peripheral circulation and their relation to food intake in the rat.

    abstract::Rats weighing about 450 g were provided with permanent catheters in the portal vein and the right auricle. This method allows blood sampling from the portal and peripheral circulation at the same moment in the nondisturbed unanesthetized rat. In the ad lib condition the portal glucose level was higher than that in the...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(77)90342-0

    authors: Strubbe JH,Steffens AB

    更新日期:1977-08-01 00:00:00

  • U.S food insecurity and population trends with a focus on adults with disabilities.

    abstract::Food insecurity is a key indicator of well-being. This article provides an overview of food security measurement and population trends with a focus on adults with disabilities and their risk for food insecurity. Food-insecure households had difficulty providing enough food for all their members due to a lack of resour...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2020.112865

    authors: Coleman-Jensen A

    更新日期:2020-06-01 00:00:00

  • Circadian rhythms of body temperature and metabolic rate in naked mole-rats.

    abstract::Body temperature (T(b)) and metabolic rate (O(2) consumption) were measured continuously in naked mole-rats. Circadian rhythms were observed for both parameters. Body temperature increased at the end of the light phase in a 12L:12D cycle in three of four animals. The remaining animal exhibited a freerunning rhythm of ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(00)00280-8

    authors: Riccio AP,Goldman BD

    更新日期:2000-10-01 00:00:00

  • Working memory deficits in BXSB mice with neocortical ectopias.

    abstract::Approximately 40-60% of BXSB/MpJ-Yaa mice exhibit neocortical ectopias, which are misplaced clusters of neurons in layer I of cortex. These ectopias are usually located in the prefrontal and/or motor region of cortex in BXSB mice, and are similar in appearance to those found in postmortem analyses of the brains of dys...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(00)00239-0

    authors: Hyde LA,Sherman GF,Hoplight BJ,Denenberg VH

    更新日期:2000-07-01 00:00:00

  • Strain differences in consumption of saline solutions by mice.

    abstract::Intake of saline (NaCl) solutions and water by males of two inbred strains of mice [C57BL/6J (C57) and 129/J] were examined using 48-h, two-bottle preference tests. There was a large strain difference in saline intake: at moderate concentrations (0.075-0.150 M) C57 mice tended to reject saline relative to water, where...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(93)90063-l

    authors: Beauchamp GK,Fisher AS

    更新日期:1993-07-01 00:00:00

  • Effects of medroxyprogesterone acetate on plasma testosterone and sexual behavior in male cynomolgus monkeys (Macaca fascicularis).

    abstract::Medroxyprogesterone acetate (MPA), a synthetic progestin with androgen-depleting activity, is used to treat the deviant sexual behavior of men. To investigate the effects of MPA in another anthropoid primate, 16 oppositely-sexed pairs of cynomolgus monkeys were observed in one-hour behavior tests during 15 successive ...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(88)90275-2

    authors: Zumpe D,Michael RP

    更新日期:1988-01-01 00:00:00

  • Does sex mediate the affective response to high intensity interval exercise?

    abstract::High intensity interval exercise (HIIE) is identified as an alternative to moderate intensity continuous exercise (MICE) due to its similar effects on outcomes including maximal oxygen uptake and glycemic control. Nevertheless, its widespread implementation in adults is questioned because acute HIIE elicits more avers...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2019.02.005

    authors: Astorino TA,Sheard AC

    更新日期:2019-05-15 00:00:00

  • Wrist activity in a woman: daily, weekly, menstrual, lunar, annual cycles?

    abstract::Wrist activity was monitored continuously for one year in a woman who went about her normal life. The year of data were analyzed for changes and rhythms--daily, weekly, menstrual, lunar, annual. For each day, average motions/5 minutes, activity onset, activity offset, alpha (duration of activity), and acrophase were m...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(92)90326-w

    authors: Binkley S

    更新日期:1992-09-01 00:00:00

  • Novel findings in the cephalic phase of digestion: a role for microcirculation?

    abstract::The cephalic phase of digestion (CPD) has been extensively investigated in terms of digestion and metabolism. Nevertheless, microcirculatory changes required to prepare peripheral tissues in order to dispose nutrients have never been assessed. In this study, microvascular function has been evaluated to determine its b...

    journal_title:Physiology & behavior

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.physbeh.2011.12.004

    authors: Buss C,Kraemer-Aguiar LG,Maranhão PA,Marinho C,de Souza Md,Wiernsperger N,Bouskela E

    更新日期:2012-02-28 00:00:00

  • Effects of interleukin-1 on sexual attractivity in a model of sickness behavior.

    abstract::Interleukin-1 (IL-1), a cytokine secreted by activated macrophages, inhibits sexual behavior in female but not male rats. The present study examined the effects of IL-1 on sexual attractiveness of the injected animal and on the sexual responses exhibited by its mating partner. In Experiment 1, a male rat was placed wi...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/s0031-9384(97)00381-8

    authors: Avitsur R,Cohen E,Yirmiya R

    更新日期:1997-12-31 00:00:00

  • Effect of brain lesions on rat shuttle behavior in four different tests.

    abstract::Rats were trained to perform shuttle responses to a buzzer in four different situations: pseudoconditioning or D test (buzzers and footshocks presented at random), classical conditioning or DP test (buzzers and footshocks paired on every trial), avoidance without stimulus pairing or DC test (buzzer-shock intervals var...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(79)90128-8

    authors: Schütz RA,Izquierdo I

    更新日期:1979-07-01 00:00:00

  • Of fish and mirrors: Fluoxetine disrupts aggression and learning for social rewards.

    abstract::Aggressive signaling is a key social behavior of male Siamese fighting fish (Betta splendens). Successfully establishing a territory and defending it from intruders has direct fitness effects, making Betta splendens a prime model for studies examining the biological underpinnings of aggressive behavior. Current resear...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/j.physbeh.2017.02.021

    authors: Eisenreich BR,Greene S,Szalda-Petree A

    更新日期:2017-05-01 00:00:00

  • Adapting to phase shifts, I. An experimental model for jet lag and shift work.

    abstract::An experimental model was developed to measure various behavioral and physiological parameters in a laboratory paradigm mimicking phase shifts that could occur in time-zone transitions and shift work rotas. Volunteers were exposed to 9-h pulses of bright light (1,200 lx) as follows: day (D)1: 1800-0300 h, D2: 2100-060...

    journal_title:Physiology & behavior

    pub_type: 临床试验,杂志文章

    doi:10.1016/0031-9384(95)02147-7

    authors: Deacon S,Arendt J

    更新日期:1996-04-01 00:00:00

  • Alpha 2-adrenoceptor antagonists and male sexual behavior: II. Erectile and ejaculatory reflexes.

    abstract::Three alpha 2-adrenoceptor antagonists, yohimbine, idazoxan, and imiloxan, all shown to have stimulatory effects on sexual arousal/motivation, were studied to identify their possible effects on the other two major components of male copulatory behavior: erection and ejaculation. Genital reflex ex copula tests were use...

    journal_title:Physiology & behavior

    pub_type: 杂志文章

    doi:10.1016/0031-9384(87)90124-7

    authors: Smith ER,Lee RL,Schnur SL,Davidson JM

    更新日期:1987-01-01 00:00:00