Maze performance in rats with hippocampal perforant paths lesions: some aspects of functional recovery.

Abstract:

:The performance of two experimental groups--one with lesions of the perforant paths projecting to the dorsal hippocampus (the D group) and one with lesions of the perforant paths to both the dorsal and ventral hippocampus (the DV group)--was compared with the performance of a lesioned control group and an intact control group during two test sessions in the Hebb-Williams maze. Both experimental groups displayed impaired maze learning in Session I. The DV group showed some recovery of function in Session II, and the D group was indistinguishable from controls. The results are discussed in terms of reduced sensory information to the hippocampal formation resulting from perforant paths lesions. It is suggested that the hippocampus is involved in relating new stimuli to previous experience.

journal_name

Physiol Behav

journal_title

Physiology & behavior

authors

Myhrer T

doi

10.1016/0031-9384(75)90210-3

subject

Has Abstract

pub_date

1975-10-01 00:00:00

pages

433-7

issue

5

eissn

0031-9384

issn

1873-507X

pii

0031-9384(75)90210-3

journal_volume

15

pub_type

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