Abstract：
:Post-exertional exacerbation of symptoms is one of the major characteristics of chronic fatigue syndrome (CFS). In this study, we evaluated the hypothesis that disturbances in circadian chronobiological regulation may play a role in generating this phenomenon. We recorded physical activity for 6-day periods in 16 women (10 CFS and 6 sedentary healthy controls, CON) before and after performing a maximal treadmill test. We calculated activity rhythms by computing autocorrelation coefficients by cutting 1 day apart from the data as a template and sliding it sequentially through each of the other days; all of 6 days were used as the templates. The peak value of autocorrelation coefficient (R) and the time between peak R's (circadian period, CP) were calculated. CFS patients had a lengthening (P < .05) of mean circadian period (MCP) that was longer than 24 h (P < .05), while MCP in CON remained unchanged. No difference was found in the standard error of each subject's MCP (circadian period variability, CPV) before and after exercise for both groups. We interpret this increase in circadian rest-activity period seen in CFS patients following exercise to indicate that exhaustive exercise interferes with normal entrainment to 24-h zeitgeber(s). This effect may be associated in part with the common patient complaint of symptom worsening following exertion.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Ohashi K,Yamamoto Y,Natelson BHdoi
10.1016/s0031-9384(02)00808-9subject
Has Abstractpub_date
2002-09-01 00:00:00pages
39-44issue
1eissn
0031-9384issn
1873-507Xpii
S0031938402008089journal_volume
77pub_type
杂志文章abstract：:Two experiments were performed to examine the acute effects of thirst-inducing stimuli upon the intake of tap water and ethanol solutions by golden hamsters, a species which avidly consumes ethanol solutions. In Experiment 1, three groups of adult male hamsters (n = 6/group) were maintained on Purina chow and tap wate...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(90)90353-6
更新日期：1990-06-01 00:00:00
abstract：:Rats were trained to perform shuttle responses to a buzzer in four different situations: pseudoconditioning or D test (buzzers and footshocks presented at random), classical conditioning or DP test (buzzers and footshocks paired on every trial), avoidance without stimulus pairing or DC test (buzzer-shock intervals var...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(79)90128-8
更新日期：1979-07-01 00:00:00
abstract：:Environmental temperature can strongly affect sleep. The habitual sleep phase is usually located between evening decline and morning rise of the circadian rhythm of core body temperature (CBT). However, the thermophysiological mechanisms promoting or disturbing sleep are not yet fully understood. The purpose of this s...
journal_title：Physiology & behavior
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.physbeh.2017.12.014
更新日期：2018-03-01 00:00:00
abstract：:Following training with distinctively flavored solutions which differ in calories and thus in their postingestive effects, rats demonstrate flavor-postingestive consequence learning by preferentially consuming one of the flavors in two-bottle tests (both flavors presented in nutrient-identical solutions). The directio...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00345-4
更新日期：1997-12-01 00:00:00
abstract：:A new demand feeder was designed for the automatic and accurate feeding of fish. The feeding device is microcomputer controlled and permits the continuous recording of feeding behaviour. The electromechanical feeder consists of a sliding door powered by a solenoid which provides only one weighed pellet when activated ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(94)90244-5
更新日期：1994-10-01 00:00:00
abstract：:The predatory behavior of female ferrets shows seasonal fluctuations which appear to be affected by estradiol. Under natural lighting conditions in the laboratory the annual rhythm of the behavior was observed during anestrus, estrus, pregnancy, pseudopregnancy and lactating period. Females in heat failed to show pred...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(86)90287-8
更新日期：1986-01-01 00:00:00
abstract：:The feeding response following administration of the anti-metabolic glucose analogue, 2-deoxy-d-glucose (2DG), is conceptualized as an experimental model of glucoprivation, which may contribute to the understanding of inter-individual differences in glucose and carbohydrate intake and, ultimately, obesity. Although va...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2005.12.002
更新日期：2006-03-30 00:00:00
abstract：:Prenatal stress (heat and restraint) reduced pregnancy-induced and elevated postpartum aggression in Rockland-Swiss (R-S) albino female mice. Though prenatally-stressed females were indistinguishable from control animals with respect to parental behavior during the virgin state, the former displayed slightly lower lev...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(88)90252-1
更新日期：1988-01-01 00:00:00
abstract：:The aim of the study was to investigate the illuminance selected in the morning by subjects whose face was cooled and whose tympanic temperature has been lowered by 0.15-0.25 degrees C. The hypothesis tested was that a difference between the actual core temperature and its set point (load error) will influence the pre...
journal_title：Physiology & behavior
pub_type： 临床试验,杂志文章
doi：10.1016/j.physbeh.2003.12.015
更新日期：2004-03-01 00:00:00
abstract：:The reactions elicited by nociceptive stimulations were studied in mice exposed to the presence of different odors: positive (attractive), negative (aversive), or neutral. In a first set of experiments, the animals were not habituated to the odors before the nociceptive stimuli were applied; in this case, the olfactor...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00024-3
更新日期：1997-08-01 00:00:00
abstract：:This study mainly explored the thermal comfort from the perspective of physiology. Three physiological parameters, including skin temperature (local and mean), electrocardiograph (ECG) and electroencephalogram (EEG), were investigated to see how they responded to the ambient temperature and how they were related to th...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2007.09.012
更新日期：2008-01-28 00:00:00
abstract：:Today, there are still uncertainties about the role of exogenous fat on body fat regulation. Early models of energy utilization (for example, Kleiber's, early 20th century) failed to take into account the nature of substrate oxidized in the control of food intake, whereas more recent models (e.g., Flatt's model, end o...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2004.09.015
更新日期：2004-12-30 00:00:00
abstract：:The obesity epidemic is a major health and economic burden facing both developed and developing countries worldwide. Interrogation of the central and peripheral mechanisms regulating ingestive behaviors have primarily focused on food intake, and in the process uncovered a detailed neuroanatomical framework controlling...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2017.10.006
更新日期：2018-06-01 00:00:00
abstract：:Rats were weaned early (Day 15), normally (Day 21) or late (Day 27). When they reached 200 g (+/- 10) they were placed into the activity-stress paradigm. Half the rats in each weaning group were housed in activity-wheel cages and fed only 1 hr each day. The remaining rats served as food-yoked home cage controls and we...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(85)90012-5
更新日期：1985-06-01 00:00:00
abstract：:The palatability of food has been shown to influence the cephalic phase reflexes. To determine if food palatability affects the magnitude of cephalic phase insulin release (CPIR) in humans, normal-weight women were asked to list foods that they found palatable and unpalatable. Subjects then stayed overnight in the hos...
journal_title：Physiology & behavior
pub_type： 临床试验,杂志文章
doi：10.1016/s0031-9384(96)80033-3
更新日期：1996-08-01 00:00:00
abstract：:Using microdialysis, we showed recently that hypothalamic immuno-reactive insulin (IRI) levels increased after a meal of chow and decreased in response to a fat meal. In the present study, we have compared extracellular hypothalamic and extrahypothalamic basal IRI levels and investigated the effect of meals composed e...
journal_title：Physiology & behavior
pub_type： 更正并重新发布的文章,杂志文章
doi：10.1016/s0031-9384(99)00061-x
更新日期：1999-03-01 00:00:00
abstract：:The role of maternal care in mediating variation in offspring phenotype has been examined in the rat and demonstrates that mother-infant interactions are critical for inducing long-term changes in behavior. Though phenotypic differences between mice strains are often attributed to genetic factors, the influence of ear...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2007.03.014
更新日期：2007-06-08 00:00:00
abstract：:This study examined the effects of a fungal infection on body temperature (Tb) and sleep states. Tb and sleep were recorded in male rats for 24 hr after a saline injection and 48 hr after a subcutaneous injection of live brewer's yeast, at ambient temperatures (Ta's) of 20 degrees and 30 degrees C. Peak fevers of 1.6-...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(88)90051-0
更新日期：1988-01-01 00:00:00
abstract：:Rats' ability to discriminate their hormonal states was examined by observing the effects of ovarian steroids on state-dependent learning using a drug discrimination task. A rat's entry into the correct arm (left or right) of a Y-maze terminated mild foot shock. The arm designated as correct was alternated daily, but ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(95)00146-a
更新日期：1995-11-01 00:00:00
abstract：:Studied were isolation induced effects in guinea pigs. Males (CM) living in two colonies (12 males, 12 females, each) were compared to males (IM) born in the colonies and kept isolated from their 2nd month of age. The findings were: At 19 months of age CM showed higher testosterone and cortisol titers, higher adrenal ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(86)90129-0
更新日期：1986-01-01 00:00:00
abstract：:Patients suffering from depression-associated cognitive impairments often recover incompletely after remission from the core symptoms of depression (lack of energy, depressed mood and anhedonia). This study aimed to set the basis for clinically relevant testing of cognitive impairments in a preclinical model of depres...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2017.11.010
更新日期：2018-02-01 00:00:00
abstract：:Parkinson's disease (PD) is the second most common neurodegenerative disorder characterized by the specific and massive loss of dopamine (DA) containing neurons in the substantia nigra pars compacta (SNpc) and aggregation of protein α-synuclein. There are a few animal studies, which indirectly implicate the neuroprote...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2015.08.025
更新日期：2015-11-01 00:00:00
abstract：:Rats housed in social isolation postweaning (isolates) show profound behavioral and neurobiological differences when compared to socially housed rats (socials). Fischer rats (F344) relative to Lewis rats are hyperresponsive and significantly more susceptible to stressful stimuli. This investigation tested the hypothes...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(99)00193-6
更新日期：2000-01-01 00:00:00
abstract：:Bulimia nervosa (BN) is a psychiatric illness characterized by eating binges followed by inappropriate behavioral attempts to compensate for the binges, usually vomiting or laxative abuse. Patients with BN have disturbances in the development of satiety during a meal as well as disturbances in functions of the upper g...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2005.11.010
更新日期：2006-02-28 00:00:00
abstract：:Rats placed as intruders in a long-established colony showed significant elevations of plasma corticosterone after 10-20 minutes of intruding. This rise was prevented by 5 days pretreatment with chlordiazepoxide (5 mg/kg). The rats resident in the colony had significantly higher basal corticosterone concentrations com...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(84)90152-5
更新日期：1984-09-01 00:00:00
abstract：:The effects of central infusion of naloxone into the midbrain periaqueductal gray (PAG) upon predatory attack behavior in the cat were studied in 12 cats. Initially, quiet biting attack was elicited by electrical stimulation of sites within the lateral hypothalamus using monopolar electrodes. Then cannula-electrodes w...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(91)90337-n
更新日期：1991-06-01 00:00:00
abstract：:The effect of exercise on central nervous system function was investigated in relation to the mechanism of calcium-calmodulin-dependent dopamine synthesis in the brain. It is shown here through animal experiments that exercise leads to an increase in the calcium level in the brain. This in turn enhances brain dopamine...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(96)00011-x
更新日期：1996-07-01 00:00:00
abstract：:A large part of domestic food intake may be determined by retail food purchase behavior, and it is commonly believed that this may be significantly influenced by the shopper's state of food deprivation. In the present study, 198 subjects recruited just prior to shopping at a large supermarket completed questionnaires ...
journal_title：Physiology & behavior
pub_type： 临床试验,杂志文章
doi：10.1016/s0031-9384(96)00241-7
更新日期：1996-11-01 00:00:00
abstract：:In nature the degu has been observed to deposit and to investigate scents. This study employed a captive group of these animals to investigate their responses to conspecific urinary marks in a neutral arena. Both sex classes served as subjects. They were presented with urine obtained from males, from females and a sal...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(85)90027-7
更新日期：1985-06-01 00:00:00
abstract：:General arousal has been operationally defined as an enhanced motor activity and enhanced intensity of response to sensory stimuli. Even though the effects of gonadal hormones on mating behavior have been much studied, their potential effect on generalized arousal, as defined above, has never been evaluated. In the pr...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2015.04.053
更新日期：2015-08-01 00:00:00
