Effect of marital status on duodenal adenocarcinoma survival: A Surveillance Epidemiology and End Results population analysis.

abstract：:Pristimerin is an active compound isolated from the traditional Chinese herbs Celastraceae and Hippocrateaceae. It has been reported to exert antitumor effects under experimental and clinical conditions; however, the antitumor effects and underlying mechanisms of pristimerin in oral cancer cells have not yet been iden...

journal_title：Oncology letters

authors： Wu H,Li L,Ai Z,Yin J,Chen L

更新日期：2019-03-01 00:00:00

abstract：:Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy, and it is often observed to overexpress epidermal growth factor receptor (EGFR). Previous research has indicated that EH domain-containing 1 (EHD1) is associated with EGFR-mediated endocytotic recycling in multiple tumor types. The objective...

journal_title：Oncology letters

authors： Liu Y,Liang Y,Li M,Liu D,Tang J,Yang W,Tong D,Jin X

更新日期：2018-10-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) exhibit an important function in extracellular matrix degradation. MMPs modulate the activation of growth factors, cytokines and metastasis. At present, the effect of exercise on serum levels of MMP-2 and -9 remains unclear. The aim of the present study was to investigate the effect of...

journal_title：Oncology letters

authors： Giganti MG,Tresoldi I,Sorge R,Melchiorri G,Triossi T,Masuelli L,Lido P,Albonici L,Foti C,Modesti A,Bei R

更新日期：2016-09-01 00:00:00

abstract：:Serine/threonine kinase 39 (STK39) is associated with hypertension, autism, Parkinson's disease and various types of cancer in recent years. This study investigated STK39 expression and possible roles in osteosarcoma using qPCR and western blot analysis. Compared to normal bone tissues, the mRNA and protein expression...

journal_title：Oncology letters

authors： Huang T,Zhou Y,Cao Y,Tao J,Zhou ZH,Hang DH

更新日期：2017-10-01 00:00:00

abstract：:The aim of the present study was to investigate the association between methylation of cyclin-dependent kinase inhibitor 2B (CDKN2B) CpG islands and telomerase activity in children with acute lymphoblastic leukemia (ALL). A total of 72 children with ALL and 12 children with immune thrombocytopenia (ITP) were subjected...

journal_title：Oncology letters

authors： Hu Q,Chen X,Liu S,Wen R,Yuan X,Xu D,Liu G,Wen F

更新日期：2017-04-01 00:00:00

abstract：:A 39-year-old female presented to The First Affiliated Hospital of Jishou University (Jishou, Hunan) with a fever of unknown origin and progressive abdominal distension. Physical examination revealed generalized lymphadenopathy, multiple non-tender cutaneous nodules, hepatomegaly, splenomegaly and abdominal edema. An ...

journal_title：Oncology letters

authors： Song K,Li M

更新日期：2015-05-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) are enzymes for extracellular matrix remodeling that are involved in tumor growth, progression and metastasis. Among them, MMP-9 has been implicated in tumor angiogenesis. Tissue inhibitor of matrix metalloproteinase (TIMP)-2, a member of the family of MMP inhibitors, induces apoptosis...

journal_title：Oncology letters

authors： Wajner SM,Capp C,Brasil BA,Meurer L,Maia AL

更新日期：2014-03-01 00:00:00

abstract：:TERT is the main functional unit of telomerase, which maintains telomere length and chromosome structure stability. TERT has been shown to act as a key factor in various biological processes, such as cell proliferation, via uncharacterized mechanisms. We transfected HEp-2 laryngeal carcinoma cells with a TERT overexpr...

journal_title：Oncology letters

authors： Jiang Y,Chen C,Chen SM,Wang YQ,Xu Y,Wang Y,Chen Z,Xiao BK,Tao ZZ

更新日期：2013-07-01 00:00:00

abstract：:Cervical cancer is the third most common malignancy worldwide, accounting for 250,000 mortalities annually. Notch1, an important regulator of cell-fate decisions and differentiation, has been found to be overexpressed in certain types of cancer. However, the role of Notch1 in cervical carcinogenesis remains unclear. I...

journal_title：Oncology letters

authors： Sun Y,Zhang R,Zhou S,Ji Y

更新日期：2015-06-01 00:00:00

abstract：:Notch signaling is well-known for its role in regulating cell self-renewal and differentiation. Within the cancer research field, it has been identified that dysregulated Notch signaling is involved directly with various types of cancer. Although Notch signaling is generally considered as oncogenic, it sometimes acts ...

journal_title：Oncology letters

authors： Jia D,Underwood J,Xu Q,Xie Q

更新日期：2019-06-01 00:00:00

abstract：:TACC3, a member of the transforming acidic coiled-coil protein (TACC) family, is a multifunctional protein that is involved in various biological functions, including proliferation and differentiation of tumor cells, cancer progression and metastasis. The aims of the present study were to examine whether TACC3 express...

journal_title：Oncology letters

authors： Zhao C,He X,Li H,Zhou J,Han X,Wang D,Tian G,Sui F

更新日期：2018-05-01 00:00:00

abstract：:Aryl hydrocarbon receptor nuclear translocator (ARNT) is a transcription factor that has been reported to play a vital role in regulating glycolysis, angiogenesis and apoptosis. Recently, ARNT has been reported to a play role in pancreatic-islet function in type 2 diabetes. However, the role of ARNT in kidney cancer h...

journal_title：Oncology letters

authors： Zhao Y,Han F,Zhang X,Zhou C,Huang D

更新日期：2020-10-01 00:00:00

abstract：:To aim of the present study was to investigate the association between special AT-rich DNA-binding protein-1 (SATB1) expression and liver cancer metastasis. SATB1 mRNA and protein expression in hepatocellular carcinoma tissues was analyzed by immunohistochemistry, and in two hepatocellular cancer cell lines, MHCC-97H ...

journal_title：Oncology letters

authors： Wu D,Zeng L,Liu F,Zhong Q,Zhang D,Cai C,Zhang W,Wu L,Chen H

更新日期：2016-12-01 00:00:00

abstract：:MicroRNA (miR)-29a has been associated with carcinogenesis in humans; however, its functional significance in esophageal squamous cell carcinoma (ESCC) is yet to be determined. In the present study, the expression of miR-29a was markedly downregulated in ESCC tissue and the ESCC TE-1 cell line, compared with normal es...

journal_title：Oncology letters

authors： Liu C,Duan P,Li B,Huang C,Jing Y,Yan W

更新日期：2015-01-01 00:00:00

abstract：:Multifocal epithelial hyperplasia (MEH), also known as Heck's disease, manifests as a papulonodular lesion in the oral mucosa and has been associated with the human papillomavirus, a virus related to various precancerous diseases in the oral cavity. It has a predisposition for the female gender and for children. Altho...

journal_title：Oncology letters

authors： Bascones-Martínez A,Cok S,Bascones-Ilundáin C,Arias-Herrera S,Gomez-Font R,Bascones-Ilundáin J

更新日期：2012-02-01 00:00:00

abstract：:Imaging techniques of upper tract urothelial carcinoma (UTUC) are presently limited. Upconversion particles (UCPs) could be used to target tumors for imaging. The present study aimed to assess the value of a nano-UCP as a diagnostic probe for deep tumor tissue, including UTUC. Polymer-coated water-soluble UCPs were sy...

journal_title：Oncology letters

authors： Liao G,Wang L,Yu W

更新日期：2018-11-01 00:00:00

abstract：:Ganglioneuromas (GNs) arising from neural crest sympathogonia are rare benign neurogenic tumors. The most commonly affected sites are the posterior mediastinum, the retroperitoneum and the adrenal gland. GNs often present as a solitary, painless and slow-growing mass, and multiple occurrences in the cervical region ar...

journal_title：Oncology letters

authors： Ma J,Liang L,Liu H

更新日期：2012-09-01 00:00:00

abstract：:Despite advances in the diagnosis and treatment in recent years, lung cancer is still one of the primary causes of cancer-associated morbidity and mortality in globally. Abnormally expressed microRNAs (miRNAs/miRs) in tumor tissues serve vital roles in the pathological mechanism of tumors and have become prospective b...

journal_title：Oncology letters

authors： Zhuo E,Cai C,Liu W,Li K,Zhao W

更新日期：2020-12-01 00:00:00

abstract：:In recent decades, thyroid cancer (TC) has become one of the most common endocrine malignancies. Next-generation sequencing of paired TC and adjacent healthy thyroid tissues demonstrated that polycystic kidney and hepatic disease 1-like 1 (PKHD1L1) may serve as a tumour suppressor gene in thyroid cancer. However, the ...

journal_title：Oncology letters

authors： Zheng C,Quan R,Xia EJ,Bhandari A,Zhang X

更新日期：2019-09-01 00:00:00

abstract：:Urothelial cancer is the most frequently diagnosed type of malignant tumor in the bladder, of which primary adenocarcinoma accounts for a small percentage. Secondary malignancies, in particular metastatic adenocarcinoma from the lung, are exceedingly rare, with only six cases previously reported in the literature. The...

journal_title：Oncology letters

authors： Ye HJ,Ma J,Liu YJ,Ye XF,Zhang LW,Li JG

更新日期：2015-09-01 00:00:00

abstract：:Protease-activated receptor 4 (PAR4), a member of the G-protein-coupled receptor family, was previously identified to be involved in the progression of cancer. Previous study revealed that the expression of PAR4 was increased in colorectal cancer tissues compared with the associated normal tissues, particularly in pos...

journal_title：Oncology letters

authors： Zhang H,Jiang P,Zhang C,Lee S,Wang W,Zou H

更新日期：2018-11-01 00:00:00

abstract：:Hepatic epithelioid angiomyolipoma (EAML) is a rare type of hepatic tumor. Due to a lack of adequate understanding about this tumor, hepatic EAML is often misdiagnosed as other diseases with similar clinical characteristics such as hepatic cancer. In the present study, 3 cases of hepatic EAML are reported, and the mai...

journal_title：Oncology letters

authors： Liu W,Meng Z,Liu H,Li W,Wu Q,Zhang X,E C

更新日期：2016-06-01 00:00:00

abstract：:Transcriptional co-activator with PDZ-binding motif (TAZ) is a transcriptional co-activator which binds to a variety of transcription factors. An increasing number of studies have provided evidence that TAZ may be a positive regulator of cell proliferation and tumorigenesis. To reveal the underlying mechanisms by whic...

journal_title：Oncology letters

authors： Yang L,Huang M,Tan J,Hou J,He J,Wang F,Cui H,Yi L

更新日期：2017-06-01 00:00:00

abstract：:Abnormal regulation of long non-coding RNAs (lncRNAs) appears to be a primary feature of numerous types of human cancer. However, the association between the dysregulation of lncRNAs and functional alterations in gastric cancer (GC) remains unclear. In previous studies, we applied microarray and bioinformatics analyse...

journal_title：Oncology letters

authors： Li CY,Liang GY,Yao WZ,Sui J,Shen X,Zhang YQ,Ma SM,Ye YC,Zhang ZY,Zhang WH,Yin LH,Pu YP

更新日期：2018-06-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDA) is an aggressive malignant disease that is resistant to various chemotherapeutic agents and commonly relapses. Efficient elimination of metastasized PDA is critical for a positive post-surgical treatment outcome. The present study analyzed the effect of the B-cell lymphoma-2 (Bcl...

journal_title：Oncology letters

authors： Kasai S,Sasaki T,Watanabe A,Nishiya M,Yasuhira S,Shibazaki M,Maesawa C

更新日期：2017-07-01 00:00:00

abstract：:Keloids are a type of benign hyperplasia that cause dermatologic dysfunction and esthetic deformity by invading adjacent normal tissues. Little is known about their etiology, therefore, they are a challenge to treat using plastic surgery. In a previous study, it was demonstrated that the expression of the long non-cod...

journal_title：Oncology letters

authors： Li Y,Liang X,Wang P,Long X,Wang X,Meng Z

更新日期：2018-07-01 00:00:00

abstract：:The aim of the present study was to identify and characterize side population (SP) cells in primary cervical cancer. A primary culture was successfully established, and the SP cells were isolated via fluorescence-activated cell sorting. Subsequently, in vitro analysis of clonogenic capacity by soft agar assay and in v...

journal_title：Oncology letters

authors： Wei ZT,Yu XW,He JX,Liu Y,Zhang SL

更新日期：2017-09-01 00:00:00

abstract：:Nordihydroguaiaretic acid (NDGA) and its derivatives possess anti-cancer effects on various types of cancer via the induction of apoptosis or cell cycle arrest. This study proved that NDGA inhibited cervical cancer SiHa cell growth and induced cell cycle arrest at the G(1) phase, which may be a consequence of cell cyc...

journal_title：Oncology letters

authors： Gao P,Zhai F,Guan L,Zheng J

更新日期：2011-01-01 00:00:00

abstract：:Hyperbaric oxygenation (HBO) on postoperative rehabilitation of brain tumors and effects on tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) levels were explored. A retrospective analysis of 132 patients with brain tumors treated in the People's Hospital of Rizhao from October 2014 to October 2017 was performe...

journal_title：Oncology letters

authors： Hou S,Wu G,Liang J,Cheng H,Chen C

更新日期：2019-03-01 00:00:00

abstract：:Metabolic reprogramming is a hallmark of cancer cells and is used by cancer cells for growth and survival. Pyruvate kinase muscle isozyme M2 (PKM2) is a limiting glycolytic enzyme that catalyzes the final step in glycolysis, which is key in tumor metabolism and growth. The present review discusses the expression and r...

journal_title：Oncology letters

authors： Dong G,Mao Q,Xia W,Xu Y,Wang J,Xu L,Jiang F

更新日期：2016-03-01 00:00:00