Long non-coding RNA CACNA1G-AS1 promotes calcium channel protein expression and positively affects human keloid fibroblast migration.

abstract：:Lichen sclerosus is a chronic and inflammatory disease. Extensive studies have focused on the epidermis, with the dermis or epidermis-dermis receiving less attention. To investigate the role of galectin-7, a keratinocyte protein, in vulvar lichen sclerosus (VLS) and its potential effects on dermal fibroblasts, immunoh...

journal_title：Oncology letters

authors： Zhao Y,Zhao S,Li H,Qin X,Wu X

更新日期：2018-08-01 00:00:00

abstract：:Expression of claudin-6 (CLDN6) in the tissues of gastric cancer patients and its association with clinical pathology and prognosis were investigated. A retrospective analysis was performed on 213 gastric cancer patients diagnosed and surgically treated in the Central Hospital of Zibo from January 2010 to January 2013...

journal_title：Oncology letters

authors： Gao F,Li M,Xiang R,Zhou X,Zhu L,Zhai Y

更新日期：2019-05-01 00:00:00

abstract：:Small cell lung cancer (SCLC) is a type of lung cancer characterized by a rapid disease progression and poor prognosis. Its diagnosis is often accompanied by distant metastasis. A literature review revealed that metastases to the stomach from breast, lung and esophageal cancer are frequently reported. While SCLC is a ...

journal_title：Oncology letters

authors： Peng Y,Liu Q,Wang Y,Song A,Duan H,Qiu Y,Li Q,Cui HJ

更新日期：2019-08-01 00:00:00

abstract：:Severe hemorrhage following a prostatectomy is a rare and serious complication. A 63-year-old male with severe hemorrhage following radical prostatectomy which led to hypovolemic shock presented at our department and was treated with superselective internal iliac arterial embolization. At 6 months follow-up, the patie...

journal_title：Oncology letters

authors： Cheng S,Xu L,Li G,Chen Y,Hu H,Zhang Z,Ding G

更新日期：2012-09-01 00:00:00

abstract：:The transient receptor potential melastatin member 8 (TRPM8) is a newly characterized oncoprotein involved in various malignant tumors. However, its expression pattern and biological function in osteosarcoma remain unclear. The present study aimed to explore the expression and prognostic significance of TRPM8 in osteo...

journal_title：Oncology letters

authors： Zhao W,Xu H

更新日期：2016-08-01 00:00:00

abstract：:Micheliolide (MCL), a sesquiterpene lactone isolated from Michelia compressa and Michelia champaca, has been used previously to inhibit the NF-κB signaling pathway. MCL has exerted various therapeutic effects in numerous types of disease, such as inflammatory and cancer. However, to the best of our knowledge, its unde...

journal_title：Oncology letters

authors： Feng D,Liu M,Liu Y,Zhao X,Sun H,Zheng X,Zhu J,Shang F

更新日期：2020-10-01 00:00:00

abstract：:2',4'-dihydroxy-6'-methoxychalcone (cardamonin) is a natural compound with anti-proliferative effects on several cancer types including nasopharyngeal carcinoma. The effects of cardamonin on melanoma cells are unknown. The present study investigated the anti-proliferative effect of cardamonin on human melanoma cell li...

journal_title：Oncology letters

authors： Yue Y,Liu L,Liu P,Li Y,Lu H,Li Y,Zhang G,Duan X

更新日期：2020-02-01 00:00:00

abstract：:The aim of the present study was to analyze potential therapy targets for prostate cancer using integrated analysis of two gene expression profiles. First, gene expression profiles GSE38241 and GSE3933 were downloaded from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) between prostate can...

journal_title：Oncology letters

authors： Zhao R,Wang Y,Zhang M,Gu X,Wang W,Tan J,Wei X,Jin N

更新日期：2017-11-01 00:00:00

abstract：:Myelolipoma is a rare, benign neoplasm composed of mature adipocytes and hematopoietic tissue, mainly occurring in the adrenal glands. The majority of extra-adrenal myelolipomas have been identified in the presacral region and primary mediastinal myelolipoma is very rare. Computed tomography (CT) and magnetic resonanc...

journal_title：Oncology letters

authors： Geng C,Liu N,Yang G,Qi M,Chen W

更新日期：2013-03-01 00:00:00

abstract：:Toll-like receptor 4 (TLR4) and the interleukin (IL)-23/IL-17A axis serve an important role in tumor immunology. In the present study, the activation of the TLR4/myeloid differentiation primary response 88 (MyD88)-mediated signal transduction pathway in human hepatocellular carcinoma (HCC) cells was examined using imm...

journal_title：Oncology letters

authors： Kang Y,Su G,Sun J,Zhang Y

更新日期：2018-06-01 00:00:00

abstract：:Preoperative radiotherapy improves local disease control and disease-free survival in patients with advanced rectal cancer; however, a reliable predictive biomarker for the effectiveness of irradiation has yet to be elucidated. Phosphorylation of H2A histone family member X (H2AX) to γ-H2AX is induced by DNA double-st...

journal_title：Oncology letters

authors： Kawashima S,Kawaguchi N,Taniguchi K,Tashiro K,Komura K,Tanaka T,Inomata Y,Imai Y,Tanaka R,Yamamoto M,Inoue Y,Lee SW,Kawai M,Tanaka K,Okuda J,Uchiyama K

更新日期：2020-09-01 00:00:00

abstract：:Pancreatic cancer is a deadly disease that is frequently associated with mortality at the time of diagnosis due to rapid metastasis, which makes it unsuitable for operative surgery, and resistant to chemotherapy and radiation therapy. Isochorismatase domain-containing protein 1 (ISOC1) has putative isochorismatase act...

journal_title：Oncology letters

authors： Cheng L,Zhao Y,Tang M,Luo Z,Wang X

更新日期：2019-05-01 00:00:00

abstract：:Microcystic adnexal carcinoma (MAC) is extremely rare among Asians, with the majority of cases presenting in Caucasian individuals. The current study describes the case of a 38-year-old Chinese woman who presented with a 10 year history of a mass in the upper lip. A biopsy resulted in a diagnosis of MAC. The patient u...

journal_title：Oncology letters

authors： Chen J,Yang S,Chen J,Liao T,Deng W,Li W

更新日期：2016-04-01 00:00:00

abstract：:The present study evaluated the expression of p53, pRb, hMLH1 and MDM2 prior to preoperative chemoradiotherapy (CRT) in patients with rectal cancer, and attempted to determine any correlation with treatment outcome. Forty-five patients with available pretreatment biopsy tissues and who received preoperative CRT were e...

journal_title：Oncology letters

authors： Nam TK,Lee JS,Kim HR,Ahn SJ,Song JY,Yoon MS

更新日期：2010-01-01 00:00:00

abstract：:This study investigated whether microRNA-183 and microRNA-141 in nasopharyngeal carcinoma (NPC) lesions are potential risk factors for poor prognosis. A total of 317 NPC patients admitted to Zhengzhou Central Hospital Affiliated to Zhengzhou University from January 2010 to March 2015 were included. Reverse transcripti...

journal_title：Oncology letters

authors： Lian J,Li Y,Yu M

更新日期：2019-01-01 00:00:00

abstract：:The aim of the present study was to detect the amplification of the human epidermal growth factor receptor 2 (HER2) gene in esophageal squamous cell carcinoma (ESCC), gastroesophageal junction adenocarcinoma (GEJAC) and gastric cancer (GC), as well as to understand the pathological meaning of HER2 gene amplification w...

journal_title：Oncology letters

authors： Huang JX,Zhao K,Lin M,Wang Q,Xiao W,Lin MS,Yu H,Chen P,Qian RY

更新日期：2013-07-01 00:00:00

abstract：:Pancreatic cancer is one of the most frequently occurring malignancies worldwide and it is the fourth most common cause of cancer-associated mortality in Western countries. Thalidomide (THD) plays an important role in tumor therapy, as it is able to promote early stage apoptosis and inhibit the process of angiogenesis...

journal_title：Oncology letters

authors： Qiao Z,Yuan J,Shen J,Wang C,He Z,Hu Y,Zhang M,Xu C

更新日期：2015-05-01 00:00:00

abstract：:Intramuscular myxoma (IM) is a benign intramuscular neoplasm composed of fibroblasts and abundant myxoid stroma. IMs most commonly affect larger skeletal muscles, while those affecting the oral and maxillofacial regions are rare, with a small number of documented cases in the available literature. The aim of the prese...

journal_title：Oncology letters

authors： Li G,Jiang W,Li W,Li J

更新日期：2014-05-01 00:00:00

abstract：:Numerous studies have suggested that microRNAs (miRNAs) potently affect hepatocarcinogenesis. However, the miRNA expression profiling in patients with hepatocellular carcinoma (HCC) of familial aggregation and hepatitis B virus (HBV) infection has not been elucidated. In the present study, the plasma miRNA expression ...

journal_title：Oncology letters

authors： Zhang EL,Gu J,Zhang ZY,Dong KS,Liang BY,Huang ZY

更新日期：2017-07-01 00:00:00

abstract：:Bone metastasis is an uncommon event in advanced gastric cancer patients and bone metastases are rarely detected as isolated lesions. However, eleven years after treatment for locally advanced gastric cancer, including total gastrectomy followed by adjuvant chemotherapy, a 49-year-old female was admitted to the IX Div...

journal_title：Oncology letters

authors： Iovino F,Orditura M,Auriemma PP,Ciorra FR,Giordano G,Orabona C,Bara F,Sergio R,Savastano B,Fabozzi A,Laterza MM,Ventriglia J,Petrillo A,Della Corte CM,DE Vita F

更新日期：2015-03-01 00:00:00

abstract：:In clinical practice ionizing radiation (IR) is primarily applied to cancer treatment in the form of fractionated dose (FD) irradiation. Despite this fact, a substantially higher amount of current knowledge in the field of radiobiology comes from in vitro studies based on the cellular response to single dose (SD) irra...

journal_title：Oncology letters

authors： Stankevicius V,Kuodyte K,Schveigert D,Bulotiene D,Paulauskas T,Daniunaite K,Suziedelis K

更新日期：2017-06-01 00:00:00

abstract：:Lung cancer is one of the most common malignant cancers in the Czech Republic in men, with the highest mortality rate of all the malignant diseases. The development of biological treatment enables study into novel personalized treatment options. This type of treatment is usually of high quality, and is often demanding...

journal_title：Oncology letters

authors： Stanek L,Springer D,Konopasek B,Vocka M,Tesarova P,Syrucek M,Petruzelka L,Vicha A,Musil Z

更新日期：2017-12-01 00:00:00

abstract：:Numerous studies have shown that marital status may be a prognostic factor in various malignancies, but little is known about its effect on duodenal adenocarcinoma. The aim of the present study was to determine the association between marital status and survival in patients with duodenal adenocarcinoma. The Surveillan...

journal_title：Oncology letters

authors： Wang N,Bu Q,Liu Q,Yang J,He H,Liu J,Ren X,Lyu J

更新日期：2019-08-01 00:00:00

abstract：:Hepcidin and ferroportin, which are known as key iron regulators, may be used in future treatments of pancreatic ductal adenocarcinoma. Iron is essential for life support; it helps oxygen molecules bind to hemoglobin and acts as an important catalytic enzyme center. However, iron overload is a risk factor for cancer, ...

journal_title：Oncology letters

authors： Toshiyama R,Konno M,Eguchi H,Asai A,Noda T,Koseki J,Asukai K,Ohashi T,Matsushita K,Iwagami Y,Yamada D,Asaoka T,Wada H,Kawamoto K,Gotoh K,Kudo T,Satoh T,Doki Y,Mori M,Ishii H

更新日期：2018-05-01 00:00:00

abstract：:Synchronous or metachronous occurrence of gastrointestinal stromal tumors (GISTs) and other primary gastrointestinal neoplasms has previously been reported. However, to the best of our knowledge, there are few studies regarding metachronous multiple GISTs and adenocarcinoma of the colon. The current case of an 80-year...

journal_title：Oncology letters

authors： Wang YP,Li Y,Song C

更新日期：2014-09-01 00:00:00

abstract：:It has been widely reported that patient-derived tumor xenografts (PDXs) are more similar to tumor tissues than conventional cancer cell lines. Kinetochore-associated protein 2 (KNTC2) is known to be upregulated specifically in tumor tissues of cancer patients and is recognized as a potential target for cancer therapy...

journal_title：Oncology letters

authors： Makita Y,Teratani M,Murata S,Hoashi Y,Matsumoto S,Kawamata Y

更新日期：2018-04-01 00:00:00

abstract：:Autophagy is an intracellular protein transport process leading to the degradation of organelles and long-lived proteins in eukaryotes. The down-regulation of autophagy observed in cancer cells has been associated with tumor progression. This study investigated autophagy induced by resveratrol, a natural compound, in ...

journal_title：Oncology letters

authors： Yamamoto M,Suzuki SO,Himeno M

更新日期：2010-05-01 00:00:00

abstract：:Periosteal chondrosarcoma is an extremely rare low-grade malignant cartilaginous tumor arising from the external bone surface. Diagnosis of periosteal chondrosarcomas may be challenging, since this condition closely resembles periosteal chondromas. It has been reported that positron emission tomography (PET) is useful...

journal_title：Oncology letters

authors： Morimoto S,Futani H,Tsuchiyama K,Fukunaga S,Tsukamoto Y,Yoshiya S

更新日期：2014-06-01 00:00:00

abstract：:Angiosarcoma is a rare and deadly malignancy originating from the vascular endothelial cells. Surgery is the most effective method to cure this disease, but for metastatic angiosarcoma, a chemotherapy-based treatment is the main therapeutic choice. However, there is currently no standard chemotherapy regimen. The curr...

journal_title：Oncology letters

authors： Ye J,Li XF,Wang YD,Yuan Y

更新日期：2015-04-01 00:00:00

abstract：:Colorectal cancer (CRC) is the third leading cause of cancer-associated mortalities. Long non-coding RNAs (lncRNAs) have been identified as key regulators in the occurrence and development of CRC. The lncRNA urothelial cancer associated 1 (UCA1) has been demonstrated to promote the development of numerous different ty...

journal_title：Oncology letters

authors： Zhang L,Zheng C,Sun Z,Wang H,Wang F

更新日期：2019-10-01 00:00:00