Hyperbaric oxygen on rehabilitation of brain tumors after surgery and effects on TNF-α and IL-6 levels.

abstract：:Inflammatory myofibroblastic tumor (IMT) is a rare type of mesenchymal tumor, which may affect various organs. The preferential site for IMT in the genitourinary system is the urinary bladder, while the presence of IMT in the kidney, and particularly in the renal pelvis, is rare. In the present report, the case of a 4...

journal_title：Oncology letters

authors： Wu S,Xu R,Zhao H,Zhu X,Zhang L,Zhao X

更新日期：2015-12-01 00:00:00

abstract：:Lung cancer is one of the most lethal types of cancer, and its poor prognosis is primarily due to drug resistance and cancer recurrence. As it is associated with a low five-year survival rate, lung cancer stem cells (LCSCs) have been the subject of numerous recent studies. For these studies of LCSCs, lung cancer cell ...

journal_title：Oncology letters

authors： Wang Y,Jiang M,Du C,Yu Y,Liu Y,Li M,Luo F

更新日期：2018-05-01 00:00:00

abstract：:Cancer/testis (CT) antigens are promising targets for immunotherapy due to their restricted expression in the germ cells of the testis in healthy tissue and high immunogenicity. The aim of the present study was to determine whether transmembrane protein 31 (TMEM31) is a CT antigen and to investigate the pattern of TME...

journal_title：Oncology letters

authors： Li J,Zou X,Li C,Zhong J,Chen Y,Zhang X,Qi F,Li M,Cai Z,Tang A

更新日期：2017-04-01 00:00:00

abstract：:In our previous study, we demonstrated that type II cGMP-dependent protein kinase (PKG II) was expressed at lower levels in different human cancer cell lines and that exogenous PKG II inhibited epidermal growth factor (EGF)-induced MAPK/ERK signaling. In order to investigate its functions further in this signaling pat...

journal_title：Oncology letters

authors： Tao Y,Gu YJ,Cao ZH,Bian XJ,Lan T,Sang JR,Jiang L,Wang Y,Qian H,Chen YC

更新日期：2012-11-01 00:00:00

abstract：:Hypermethylated in cancer 1 (HIC1) is a putative suppressor gene, cooperating with TP53 in the regulation of apoptosis. The promoter site of this gene contains CpG islands susceptible to methylation. Altered methylation leads to the silencing of HIC1. Persistent loss of HIC1 function reflects the attenuation of proapo...

journal_title：Oncology letters

authors： Markowski J,Sieroń AL,Kasperczyk K,Ciupińska-Kajor M,Auguściak-Duma A,Likus W

更新日期：2015-05-01 00:00:00

abstract：:The present study aimed to measure the expression of WNT1 in ameloblastoma (AB). Immunohistochemistry was used to observe changes in WNT1 expression in 80 AB samples, 10 keratocystic odontogenic tumor (KCOT) samples and 10 normal oral mucosa (NOM) samples. Western blotting and reverse transcription-quantitative polyme...

journal_title：Oncology letters

authors： Wang GN,Zhong M,Chen Y,Ji J,Gao XQ,Wang TF

更新日期：2018-08-01 00:00:00

abstract：:The safety and immunological responsiveness of a peptide vaccine of ring finger protein 43 and 34-kDa translocase of the outer mitochondrial membrane combined with uracil-tegafur/leucovorin (UFT/LV) was previously demonstrated in metastatic colorectal cancer (CRC) in a phase I clinical trial. To clarify the survival b...

journal_title：Oncology letters

authors： Kawamura J,Sugiura F,Sukegawa Y,Yoshioka Y,Hida JI,Hazama S,Okuno K

更新日期：2018-04-01 00:00:00

abstract：:To detect the expression levels of the lethal-7 (let-7) and K-ras genes in non-small cell lung cancer (NSCLC) and investigate their significance, the expression of let-7 and K-ras was determined in cancerous tissues and pericancerous normal tissues of 31 NSCLC patients using reverse transcription-polymerase chain reac...

journal_title：Oncology letters

authors： Xia XM,Jin WY,Shi RZ,Zhang YF,Chen J

更新日期：2010-11-01 00:00:00

abstract：:The aim of this study was to examine the effects of compound Radix Sophorae Flavescentis on the proliferation of esophageal carcinoma TE-8 cells and to elucidate the mechanisms involved. For this purpose, we incubated TE-8 cells in medium containing various concentrations (0, 0.0125, 0.025, 0.05, 0.1, 0.2, 0.4 and 0.8...

journal_title：Oncology letters

authors： Yang X,Cai W,Yang Q,Lu Z,Li J,Yu J

更新日期：2015-10-01 00:00:00

abstract：:The clinicopathological characteristics of squamous cell/adenosquamous carcinoma (SC/ASC) are currently not well documented, and as the prevalence of SC/ASC is uncommon in gallbladder cancers, a prognostic marker has not yet been found. In the present study, the expression of tumor susceptibility gene (TSG) 101 and pa...

journal_title：Oncology letters

authors： Liu Z,Yang Z,Liu D,Li D,Zou Q,Yuan Y,Li J,Liang L,Chen M,Chen S

更新日期：2014-04-01 00:00:00

abstract：:Endotracheal intubation (ETI) and laryngeal mask airway (LMA) in terms of hemodynamics and reaction were compared. A total of 54 general anesthesia patients were randomized into two groups with 27 cases in each group. Acceleration index (ACI), cardiac index (CI), cardiac output (CO), left cardiac work (LCW), systemic ...

journal_title：Oncology letters

authors： Song Z,Tan J,Fang J,Bian Q,Gu L

更新日期：2019-02-01 00:00:00

abstract：:Dopamine receptor 2 (DR2) may be a biomarker for various types of cancer. Ovarian cancer cells overexpress DR2; therefore, blocking DR2 may be a novel treatment strategy for ovarian cancer. Thioridazine, a DR2 blocker, has antineoplastic activity in a variety of cancer cells. In view of the requirement for novel thera...

journal_title：Oncology letters

authors： Yong M,Yu T,Tian S,Liu S,Xu J,Hu J,Hu L

更新日期：2017-12-01 00:00:00

abstract：:As a member of the tripartite motif family, tripartite motif-containing protein 59 (TRIM59) serves as an E3 ubiquitin ligase in various cellular processes, including intracellular signaling, development, apoptosis, protein quality control, innate immunity, autophagy and carcinogenesis. The present study aimed to inves...

journal_title：Oncology letters

authors： Lou M,Gao Z,Zhu T,Mao X,Wang Y,Yuan K,Tong J

更新日期：2020-02-01 00:00:00

abstract：:Actinomycosis is a chronic disease characterized by slow progression, abscess formation, tissue fibrosis and draining sinuses. Occurrence originating from the nasopharynx is extremely low. The present study described the case of a 46-year-old otherwise healthy female, with no remarkable history of mucosal injury or te...

journal_title：Oncology letters

authors： Lin YH,Hu C,Chuang HW,Lin MY

更新日期：2015-07-01 00:00:00

abstract：:MicroRNA (miRNA or miR)-298 has been reported to be downregulated and to modify the expression of the polycomb protein enhancer of zeste 2 (EZH2) in recurrent epithelial ovarian cancer (EOC). To date, no functional evidence of a miR-298-EZH2 axis in EOC has been documented. The present study aimed to investigate the a...

journal_title：Oncology letters

authors： Zhou F,Chen J,Wang H

更新日期：2016-11-01 00:00:00

abstract：:Targeted therapy of non-small cell lung cancer (NSCLC) patients with mutations in the epidermal growth factor receptor (EGFR) gene has been associated with improved prognosis. However, there is a shortage on data from real-world clinical practice in management of EGFR-positive NSCLC patients in Poland. The present stu...

journal_title：Oncology letters

authors： Ramlau R,Krawczyk P,Dziadziuszko R,Chmielewska I,Milanowski J,Olszewski W,Stencel K,Ramlau-Piątek K,Segiet A,Skroński M,Grudny J,Chorostowska-Wynimko J

更新日期：2017-11-01 00:00:00

abstract：:The aim of the present study was to identify and characterize side population (SP) cells in primary cervical cancer. A primary culture was successfully established, and the SP cells were isolated via fluorescence-activated cell sorting. Subsequently, in vitro analysis of clonogenic capacity by soft agar assay and in v...

journal_title：Oncology letters

authors： Wei ZT,Yu XW,He JX,Liu Y,Zhang SL

更新日期：2017-09-01 00:00:00

abstract：:Imiquimod is an imidazoquinoline immune response modifier that is used in antiviral and antiallergic creams. Combination therapy using transcutaneous imiquimod and oral sorafenib was previously demonstrated to reduce the tumor burden of renal cell carcinoma growing cutaneously in a mouse model. In the present study, a...

journal_title：Oncology letters

authors： Karashima T,Udaka K,Niimura M,Suzuki K,Osakabe H,Shimamoto T,Fukata S,Inoue K,Kuroda N,Seiki M,Shuin T

更新日期：2017-07-01 00:00:00

abstract：:Pyruvate kinase isoenzyme M2 (PKM2) has previously been identified as a tumor biomarker and as a potential target for cancer therapy. In this study, F§FJ-5, a characterized naphthoquinone modifier of mollugin, was synthesized in order to investigate its anticancer activity and the potential mechanisms. It was observed...

journal_title：Oncology letters

authors： Wei X,Li M,Ma M,Jia H,Zhang Y,Kang W,Wang T,Shi X

更新日期：2017-02-01 00:00:00

abstract：:This study investigated the mRNA levels of thymidylate synthetase (TYMS) and dihydropyrimidine dehydrogenase (DPYD) in esophageal squamous cell carcinoma (ESCC). TYMS and DPYD gene expression was quantified using real-time RT-PCR in 56 patients with ESCC, co-amplified with glyceraldehyde-3-phosphate dehydrogenase as a...

journal_title：Oncology letters

authors： Kimura M,Kuwabara Y,Mitsui A,Ishiguro H,Sugito N,Tanaka T,Shiozaki M,Naganawa Y,Takeyama H

更新日期：2011-03-01 00:00:00

abstract：:The RAS/RAF and PI3K/PTEN signaling pathways play central roles in hepatocarcinogenesis. KRAS, NRAS, HRAS, BRAF, PIK3CA, PIK3R1 and PTEN are key cancer-related genes in the RAS/RAF and PI3K/PTEN signaling pathways. Genetic alterations in these genes often lead to the dysregulation of the two cascades. Little is known ...

journal_title：Oncology letters

authors： Hou W,Liu J,Chen P,Wang H,Ye BC,Qiang F

更新日期：2014-09-01 00:00:00

abstract：:Increasing number of microRNAs (miRNAs) have been reported to play an important role in the development and progression of non-small cell lung cancer (NSCLC). In particular, microRNA-497-5p (miR-497-5p) has been proposed as a tumor suppressor miRNA in human cancers. However, the role of miR-497-5p and its potential mo...

journal_title：Oncology letters

authors： Huang X,Wang L,Liu W,Li F

更新日期：2019-03-01 00:00:00

abstract：:Dermatofibrosarcoma protuberans (DFSP) is a relatively rare low-grade sarcoma that occasionally exhibits melanin-containing spindle cells within the tumor. Fibrosarcomatous DFSP (FS-DFSP) is a variant that is characterized by areas which are histopathologically indistinguishable from fibrosarcoma. In the present study...

journal_title：Oncology letters

authors： Ishida M,Okabe H

更新日期：2012-09-01 00:00:00

abstract：:Non-small cell lung cancer (NSCLC) is the most frequent cancer worldwide with a poor 5-year survival. miR-650 acts as an oncogene and regulates tumor progress in various cancers. Molecular mechanisms of miR-650 in NSCLC cell proliferation and invasion was studied. The mRNA levels of miR-650 and special genes were calc...

journal_title：Oncology letters

authors： Tang X,Ding Y,Wang X,Wang X,Zhao L,Bi H

更新日期：2019-11-01 00:00:00

abstract：:The soluble urokinase-type plasminogen activator receptor (suPAR) and the urokinase-type plasminogen activator receptor (uPAR) have been proposed as useful biomarkers of tumor progression. Recently, suPAR was associated with chemoresistance in lung cancer. However, its clinical significance in leukemia has not previou...

journal_title：Oncology letters

authors： Guo H,Zhou LX,Ma H,Liu B,Cheng J,Ma YY,Zhao L

更新日期：2017-07-01 00:00:00

abstract：:The aim of the present study was to investigate the effects of the mammalian target of rapamycin (mTOR) inhibitor, RAD001, on the growth of human endometrial cancer cells. The effects of RAD001 on human endometrial cancer Ishikawa and HEC-1A cell proliferation were determined by MTT assay. Green fluorescent protein mi...

journal_title：Oncology letters

authors： Wang H,Li D,Li X,Ou X,Liu S,Zhang Y,Ding J,Xie B

更新日期：2016-12-01 00:00:00

abstract：:Pleomorphic adenomas (PAs) of salivary glands are the most frequent entity of solid parotid tumors. Nonetheless, their genetics is not yet well understood. Thus, the current study characterized 14 PAs using a unique combination of cytogenetic, molecular cytogenetic and/or molecular karyotyping based approaches. The cu...

journal_title：Oncology letters

authors： Thielker J,Weise A,Othman MAK,Carreria IM,Melo JB,Von Eggeling F,Guntinas-Lichius O,Ziegler M,Liehr T

更新日期：2020-02-01 00:00:00

abstract：:Segmental ureterectomy (SU) represents a promising alternative for the treatment of upper tract urothelial carcinomas (UTUCs) as it is a less invasive procedure and guarantees the preservation of renal units. The present study evaluated oncological outcomes and renal functions following SU when compared with radical n...

journal_title：Oncology letters

authors： Kato T,Nakayama R,Haba T,Kawaguchi M,Komiya A,Koike H

更新日期：2018-11-01 00:00:00

abstract：:The present study aimed to evaluate the expression of hypoxia-inducible factor-1α (HIF-1α) and MDR1/P-glycoprotein (P-gp) in human laryngeal squamous cell carcinoma (LSCC) tissues, and also to investigate the regulation of MDR1 gene expression by HIF-1α in Hep-2 cells under hypoxic conditions. The expression of HIF-1α...

journal_title：Oncology letters

authors： Xie J,Li DW,Chen XW,Wang F,Dong P

更新日期：2013-07-01 00:00:00

abstract：:The frequency of deficient mismatch repair (dMMR) or microsatellite instability-high colorectal cancer (CRC) is estimated to be ~15% of all patients with CRC; however, the patients reported are limited to surgical cases, and the frequency of patients exhibiting stage 0 disease is not considered, despite the currently ...

journal_title：Oncology letters

authors： Sugiyama T,Iwaizumi M,Kaneko M,Tani S,Yamade M,Hamaya Y,Furuta T,Miyajima H,Osawa S,Baba S,Maekawa M,Sugimoto K

更新日期：2020-09-01 00:00:00